In Vivo protein transduction: Delivery of PEP-1-SOD1 fusion protein into myocardium efficiently protects against ischemic insult

Molecules and Cells

Volumn 27, Issue 2, 2009, Pages 159-166

  Zhang, You En ^a   Wang, Jia Ning ^a   Tang, Jun Ming ^a   Guo, Ling Yun ^a   Yang, Jian Ye ^a   Huang, Yong Zhang ^a   Tan, Yan ^a   Fu, Shou Zhi ^a   Kong, Xia ^a   Zheng, Fei ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

Cu; Free radicals; Myocardial reperfusion injury; PEP 1 peptide; Zn SOD cell penetrating peptide

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; CREATINE KINASE; HYBRID PROTEIN; LACTATE DEHYDROGENASE; MALONALDEHYDE; OXYGEN RADICAL; DRUG DERIVATIVE; MERCAPTAMINE; PEP 1 PEPTIDE; PEP-1 PEPTIDE; PEPTIDE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEMODYNAMICS; IMMUNOFLUORESCENCE TEST; IN VIVO STUDY; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; ANIMAL; ENZYMOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; HEART MUSCLE CELL; METABOLISM; PATHOLOGY;

RATTUS;

ANIMALS; APOPTOSIS; CREATINE KINASE; CYSTEAMINE; FLUORESCENT ANTIBODY TECHNIQUE; L-LACTATE DEHYDROGENASE; MALE; MALONDIALDEHYDE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; OXIDATIVE STRESS; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECOMBINANT FUSION PROTEINS; SUPEROXIDE DISMUTASE;

EID: 66149152276     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10059-009-0020-4     Document Type: Article

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