Endophytic fungal strains of Fusarium solani, from Apodytes dimidiata E. Mey. ex Arn (Icacinaceae) produce camptothecin, 10-hydroxycamptothecin and 9-methoxycamptothecin

Phytochemistry

Volumn 71, Issue 1, 2010, Pages 117-122

  Shweta, S ^a   Zuehlke, S ^b   Ramesha, B T ^a   Priti, V ^a,c   Mohana Kumar, P ^a   Ravikanth, G ^a,c   Spiteller, M ^b   Vasudeva, R ^a   Uma Shaanker, R ^a,c  

^a UNIVERSITY OF AGRICULTURAL SCIENCES   (India)

^b TU DORTMUND UNIVERSITY   (Germany)

^c ASHOKA TRUST FOR RESEARCH IN ECOLOGY AND THE ENVIRONMENT   (India)

Author keywords

10 Hydroxycamptothecin; 9 Methoxycamptothecin; Apodytes dimidiata; Endophytic fungi; Fusarium solani camptothecin; Icacinaceae

Indexed keywords

10 HYDROXYCAMPTOTHECIN; 10-HYDROXYCAMPTOTHECIN; 9 METHOXYCAMPTOTHECIN; 9-METHOXYCAMPTOTHECIN; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; DRUG DERIVATIVE; RIBOSOME DNA;

ANGIOSPERM; ARTICLE; CHEMISTRY; FUSARIUM; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGY; MYCORRHIZA; NUCLEOTIDE SEQUENCE; TREE;

ANGIOSPERMS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BASE SEQUENCE; CAMPTOTHECIN; DNA, RIBOSOMAL; FUSARIUM; MYCORRHIZAE; TREES;

APODYTES DIMIDIATA; BACTERIA (MICROORGANISMS); FUNGI; FUSARIUM SOLANI; ICACINACEAE;

EID: 72149094874     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2009.09.030     Document Type: Article

References (32)

1. Amna T., Puri S.C., Verma V., Sharma J.P., Khajuria R.K., Musarrat J., Spiteller M., and Qazi G.N. Bioreactor studies on the endophytic fungus Entrophospora infrequens for the production of an anti-cancer alkaloid camptothecin. Can. J. Microbiol. 52 3 (2006) 189-196
2. Darzynkiewicz Z., Bruno S., Del Bino G., and Traganos F. The cell cycle effects of camptothecin. Ann. NY Acad. Sci. 803 (1996) 93-100
3. Ganeshaiah K.N. Digital Database of Plant Resources of Western Ghats India (2002), University of Agricultural Sciences, Bangalore
4. Gao D., Hyde K.D., and Liew E.C.Y. Detection and taxonomic placement of endophytic fungi within frond tissues of Livistona chinensis based on rDNA sequences. Mol. Phylogenet. Evol. 20 (2001) 1-13
5. Geoffrey, A.L., Michael, J.C., Christopher, O.M., 2000. Co-evolution of fungal endophytes with grasses: the significance of secondary metabolites. In: Charles, W.B., James, F.W., Marcel, D. (Eds.), Microbial Endophytes. New York, 487pp, ISBN:0-8247-8831-1.
6. Hombe Gowda H.C., Vasudeva R., Georgi P., Mathachen A., Uma Shaanker R., and Ganeshaiah K.N. Breeding types in Nothapodytes nimmoniana Graham: an important medicinal tree. Curr. Sci. 83 9 (2002) 1077-1078
7. Hsiang Y.H., Hertzberg R., Hecht S., and Liu L.F. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase-I. J. Biol. Chem. 260 27 (1985) 14873-14878
8. Kauh E.A., and Bjornsti M.A. SCT1 Mutants suppress the camptothecin sensitivity of yeast cells expressing wild-type DNA topoisomerase-I. Proc. Natl. Acad. Sci. USA 92 (1995) 6299-6303
9. Kusari S., Zuehlke S., and Spiteller M. An endophytic fungus from Camptotheca acuminata that produces camptothecin and analogues. J. Nat. Prod. 72 1 (2009) 2-7
10. Li J.Y., Sidhu R.S., Ford E.J., Long D.M., Hess W.M., and Strobel G.A. The induction of taxol production in the endophytic fungus-Periconia sp. from Torreya grandifolia. J. Ind. Microbiol. Biotech. 20 (1998) 259-264
11. Lorence A., and Nessler C.L. Camptothecin: over four decades of surprising findings. Phytochemistry 65 20 (2004) 2731-2841
12. Milan P., and Pinedo H.M. Camptothecins: New Anticancer Agents (1994), CRC Press, Boca Raton pp. 123-138
13. Pinkerton F., and Strobel G. Serinol as an activator of toxin production in attenuated cultures of Helminthosporium sacchari. Proc. Natl. Acad. Sci. USA 73 (1976) 4007-4011
14. Pizzolato J.F., and Saltz L.B. The camptothecins. Lancet 361 9376 (2003) 2235-2242
15. Priti V., Ramesha B.T., Shweta Singh, Ravikanth G., Ganeshaiah K.N., Suryanarayanan T.S., and Uma Shaanker R. How promising are endophytic fungi as alternative sources of plant secondary metabolites?. Curr. Sci. 97 4 (2009) 477-478
16. Puri S.C., Verma V., Amina T., Qazi G.N., and Spiteller M. An endophytic fungus from Nothapodytes foetida that produces camptothecin. J. Nat. Prod. 68 12 (2005) 1717-1719
17. Sawada S., Yokokura T., and Miyasaka Y. A-ring or E-lactone modified water-soluble prodrugs of 20(S)-camptothecin. Curr. Pharm. Des. 1 (1995) 113-132
18. Schulz B., Boyle C., Draeger S., Rommert A.K., and Krohn K. Endophytic fungi: a source of novel biologically active secondary metabolites. Mycol. Res. 106 (2002) 996-1004
19. Srivastava V., Negi A.S., Kumar J.K., Gupta M.M., and Khanuja S.P.S. Plant-based anticancer molecules: a chemical and biological profile of some important leads. Bioorg. Med. Chem. 13 21 (2005) 5892-5908
20. Stierle A., Strobel G., and Stierle D. Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of pacific yew. Science 260 (1993) 214-216
21. Strobel G.A. Microbial gifts from the rainforests. Can. J. Phyto. 24 (2002) 14-20
22. Strobel G., and Daisy B. Bioprospecting for microbial endophytes and their natural products. Microbiol. Mol. Biol. Rev. 67 (2003) 491-502
23. Suhas S., Ramesha B.T., Ravikanth G., Gunaga R.P., Vasudeva R., Ganeshaiah K.N., and Uma Shaanker R. Chemical profiling of Nothapodytes nimmoniana populations in the Western Ghats, India for anti-cancer compound. Camptothecin. Curr. Sci. 92 (2007) 1142-1147
24. Tan R.X., and Zou W.X. Endophytes: a rich source of functional metabolites. Nat. Prod. Rep. 18 (2001) 448-459
25. Torck M., and Pinkas M. Camptothecin and derivatives: a new class of antitumor agents. J. Pharm. Belg. 51 (1996) 200-207
26. Uma Shaanker R., Ramesha B.T., Ravikanth G., Rajesh P.G., Vasudeva R., and Ganeshaiah K.N. Chemical profiling of N. nimmoniana for camptothecin, an important anticancer alkaloid: towards the development of a sustainable production system. In: Ramawat K.G., and Merillion J. (Eds). Bioactive Molecules and Medicinal Plants (2008), Springer-Verlag, Berlin, Heidelberg 198-210
27. Vainio E.J., Korhonen K., and Hantula J. Genetic variation in Phlebiopsis gigantea as detected with random amplified microsatellite (RAMS) markers. Mycol. Res. 102 (1998) 187-192
28. Ved D.K. Trade in medicinal plants-the state of our ignorance. Amruth 1 10 (1997) 2-8
29. Wang A., and Li S. Hydroxy camptothecin-loaded nanoparticles enhance target drug delivery and anticancer effect. BMC Biotech. 8 (2008) 46-53
30. White T.J., Bruns T., Lee S., and Taylor J.W. Amplification and direct sequencing of fungal ribosomal RNA genes for phylogenetics. In: Innis M.A., Gelfand D.H., Sninsky J.J., and White T.J. (Eds). PCR Protocols: A Guide to Methods and Applications (1990), Academic Press, San Diego 315-322
31. Wijesekera R.O.B. The Medicinal Plant Industry (1991), CRC Press pp. 185-205
32. Yuan J.I., Jian-Nan B.I., Bing Yan., and Xu-Dong Zhu. Taxol-producing fungi: a new approach to industrial production of Taxol. Chin. J. Biotech. 22 1 (2006) 1-6