Chemical profiling of Nothapodytes nimmoniana populations in the Western Ghats, India for anti-cancer compound, camptothecin

Current Science

Volumn 92, Issue 8, 2007, Pages 1142-1147

  Suhas, S ^a   Ramesha, B T ^a   Ravikanth, G ^a,b   Gunaga, Rajesh P ^c   Vasudeva, R ^b,c   Ganeshaiah, K N ^a,b,d   Uma Shaanker, R ^a,b,d  

^a UNIVERSITY OF AGRICULTURAL SCIENCES   (India)

^b ASHOKA TRUST FOR RESEARCH IN ECOLOGY AND THE ENVIRONMENT   (India)

^c College of Forestry   (India)

^d JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

Author keywords

Camptothecin; Chemical profiling; Conservation; Icacinaceae; Nothapodytes nimmoniana; Western Ghats

Indexed keywords

ICACINACEAE; NOTHAPODYTES;

EID: 34248371209     PISSN: 00113891     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Li, S. Y. and Adair, K. T., Camptotheca acuminata Decaisne Xi Shu (Chinese Happy Tree) - A Promising Anti-tumour and Antiviral Tree for the 21st Century (ed. Stephen, F.), A Henry M. Rockwell Monograph, Austin State University, Texas, 1994.
2. Wall, M. E., Wani, M. C., Cook, C. E., Palmer, K. H., McPhail, A. T. and Sim, G. A., Plant antitumour agents-I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumour inhibitor from Camptotheca acuminata. J. Am. Chem. Soc., 1966, 88, 3888-3890.
3. Cragg, G. M. et al., International collaboration in drug discovery and development: the NCI experience. Pure Appl. Chem., 1999, 71, 1619-1633.
4. Nalawade, S. M., Abhay, P. S., Chen-Yue Lee, Chao-Lin Kao and Hsin-Sheng Tsay, Studies on tissue culture of Chinese medicinal plant resources in Taiwan and their sustainable utilization. Bot. Bull. Acad. Sin., 2003, 44, 79-98.
5. Yan, Xiu-Feng, Yang Wang, Tao Yu, Yu-Hong, Zhang and Shao-Jun Dai, Variation in camptothecin content in Camptotheca acuminata leaves. Bot. Bull. Acad. Sin., 2003, 44, 99-105.
6. Lorence, A. and Craig, L. N., Camptothecin, over four decades of surprising findings. Phytochemistry, 2004, 65, 2731-2841.
7. Lilenbaum, R. C. et al., Phase I study of paclitaxel and topotecan in patients with advanced tumours: A cancer and leukemia group B study. J. Clin. Oncol., 1995, 13, 2230-2237.
8. Romanelli, S. P., Perego, G., Pratesi, N., Carenini, M. and Tortoreto Zunino, F., In vitro and in vivo interaction between cisplatin and topotecan in ovarian carcinoma systems. Cancer Chemother. Pharmacol., 1998, 41, 385-390.
9. Vladu, B. et al., 7- and 10-Substituted camptothecins: Dependence of topoisomerase I-DNA cleavable complex formation and stability on the 7- and 10-substituents. Mol. Pharmacol., 2000, 57, 243-251.
10. Raskin, I. et al., Plants and human health in the twenty-first century. Trends Biotechnol., 2002, 12, 522-531.
11. Wall, M. E. and Wani, M. C., Plant antitumour agents II: The structure of two new alkaloids from Camptotheca acuminata. J. Org. Chem., 1968, 34, 1364-1367.
12. Govindachari, T. R. and Viswanathan, N., Alkaloids of Mappia foetida. Phytochemistry, 1972, 11, 3529-3531.
13. Hombe Gowda, H. C., Vasudeva, R., Mathachen, G. P., Uma Shaanker, R. and Ganeshaiah, K. N., Breeding types in Nothapodytes nimmoniana Graham. Curr. Sci., 2002, 83, 1077-1078.
14. Ravi Kumar and Ved, D. K., 100 Red listed medicinal plants of conservation concern in southern India. Foundation for Revitalization of Local Health Traditions, Bangalore, 2000, pp. 261-263.
15. Ved, D. K., Trade in medicinal plants - the state of our ignorance. Amruth, 1997, 1, 2-8.
16. Ciddi, V. and Shuler, M. L., Camptothecin from callus cultures of Nothapodytes foetida. Biotech. Lett., 2000, 22, 129-132.
17. Thengane, S. R., Kulkarni, D. K., Shrikhande, V. A. and Krishnamurthy, K. V., Effect of thidiazuron on adventitious shoot regeneration from seedling explants of Nothapodytes foetida. In Vitro Cell Dev. Biol. (Plant), 2001, 37, 206-210.
18. Fulzele, D. P., Satdive, R. K. and Pol, B. B., Growth and production of camptothecin by cell suspension cultures of Nothapodytes foetida. Planta Med., 2001, 67, 150-152.
19. Sundervelan, R. B., Desireddy and Ciddi, V., Camptothecine - A novel anti-cancer agent from tissue cultures of Nothapodytes foetida. Indian J. Pharm. Sci., 2002, 65, 101-105.
20. Fulzele, D. P. and Satdive, R. K., Somatic embryogenesis, plant regeneration and the evaluation of the camptothecin content in Nothapodytes foetida. Soc. In Vitro Biol., 2003, 39, 212-216.
21. Thengane, S. R., Kulkarni, D. K., Shrikhande, V. A., Joshi, S. P., Sonawane, K. B. and Krishnamurthy, K. V., Influence of medium composition on callus induction and camptothecin(s) accumulation in Nothapodytes foetida. Plant Cell Tissue Organ Cult., 2003, 72, 247-251.
22. Roja, G. and Heble, M. R., The quinoline alkaloids camptothecin and 9-methoxycamptothecin from tissue cultures and mature trees of Nothapodytes nimmoniana. Phytochemistry, 1994, 36, 65-66.
23. Padmanabha, B. V. et al., Patterns of accumulation of camptothecin, an anti-cancer alkaloid in Nothapodytes nimmoniana Graham., in the Western Ghats, India: Implications for identifying high-yielding sources of the alkaloid. Curr. Sci., 2006, 90, 95-100.
24. Ganeshaiah, K. N., Digital database of plant resources of Western Ghats, India. University of Agricultural Sciences, Bangalore, 2002.
25. Geographical coordinate database; http://www.mapsofindia.com/lat_long/ index.html.
26. Mapinfo Professional Version 7.0, Mapinfo Corporation, 1985-2002.
27. Gunasekera, S. P., Badawi, M. M., Cordell, G. A., Farnsworth, N. R. and Chitnis, M., Plant anticancer agents X. Isolation of camptothecin and 9-methoxycamptothecin from Ervatamia heyneana. J. Nat. Prod., 1979, 42, 475-477.
28. Statistica ver 4.5. Statsoft, Inc., USA, 1993.
29. Vasudeva, R., Hombe Gowda, H. C. and Raghu, H. B., Suitability of Nothapodytes nimmoniana as a profitable medicinal tree component for agroforestry systems of hill and transition zones of Karnataka. My Forest, 2004, 40, 39-44.
30. Puri, S. C., Handa, G., Gupta, R. K., Srivastava, T. N., Somal, P. and Sharma, S. N., Quantitation of camptothecin in Nothapodytes foetida. J. Indian Chem. Soc., 1999, 76, 370-371.
31. Swapna, M., Biswajit, G., Timir, B. J. and Sumita, J., Variation in content of taxol and related taxanes in Eastern Himalayan population of Taxol wallichiana. Planta Med., 2002, 68, 757-759.
32. Poupat, C., Ingrid, H., Francoise, G., Alain, A., Daniel, G. and Pierre, P., Neutral and basic taxoids in the needles of Taxus species. Planta Med., 2000, 66, 580-584.
33. Rita, M. M., Bedir, E., Barrett, H., Burandt Jr C., Canel, C. and Khan, I. A., Evaluation of Podophyllum peltatum accessions for podophyllotoxin production. Planta Med., 2002, 68, 341-344.
34. Rita, M. M., Hemanth, L., Ebru, B., Muhammed, M. and Kent, C., The American May apple and its potential for podophyllotoxin production. Trends New Crops New Uses, 2001, 36, 527-632.