Suggestive linkage at 9p22 in bipolar disorder weighted by alcohol abuse

American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

Volumn 150, Issue 8, 2009, Pages 1133-1138

  Saunders, Erika F H ^a,b,c   Zhang, Peng ^a   Copeland, J Nathan ^a   McInnis, Melvin G ^a,b   Zöllner, Sebastian ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Alcoholism; Bipolar disorder; Genetics; Linkage analysis; Mood disorder

Indexed keywords

ADULT; ALCOHOL ABUSE; ALCOHOLISM; ARTICLE; BIPOLAR DISORDER; CHROMOSOME 9P; COMORBIDITY; FAMILY STUDY; FEMALE; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ALCOHOLISM; BIPOLAR DISORDER; CHROMOSOMES, HUMAN, PAIR 9; FAMILY HEALTH; FEMALE; HUMANS; LINKAGE (GENETICS); MALE; MODELS, STATISTICAL; RISK FACTORS; UNITED STATES;

EID: 72049127778     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.30937     Document Type: Article

References (42)

1. APA. 2000. Diagnostic and statistical manual of mental disorders: DSM-IV-TR. Washington, DC:American Psychiatric Association. p 943.
2. Badner JA, Gershon ES. 2002. Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia. Mol Psychiatry 7:405-411.
3. Baldassano CF. 2006. Illness course, comorbidity, gender, and suicidality in patients with bipolar disorder. J Clin Psychiatry 67(Suppl11): 8-11. (Pubitemid 44439682)
4. Bennett P, Segurado R, Jones I, Bort S, McCandless F, Lambert D, Heron J, Comerford C, Middle F, Corvin A, Pelios G, Kirov G, Larsen B, Mulcahy T, Williams N, O'Connell R, O'Mahony E, Payne A, Owen M, Holmans P, Craddock N, Gill M. 2002. The Wellcome trust UK-Irish bipolar affective disorder sibling-pair genome screen: First stage report. Mol Psychiatry 7:189-200. (Pubitemid 34177787)
5. Bertelsen A, Harvald B, Hauge M. 1977. A Danish twin study of manicdepressive disorders. Br J Psychiatry 130:330-351. (Pubitemid 8061978)
6. Cassidy F, Ahearn EP, Carroll BJ. 2001. Substance abuse in bipolar disorder. Bipolar Disord 3:181-188.
7. Cheng R, Juo SH, Loth JE, Nee J, Iossifov I, Blumenthal R, Sharpe L, Kanyas K, Lerer B, Lilliston B, Smith M, Trautman K, Gilliam TC, Endicott J, Baron M. 2006. Genome-wide linkage scan in a large bipolar disorder sample from the national institute of mental health genetics initiative suggests putative loci for bipolar disorder, psychosis, suicide, and panic disorder. Mol Psychiatry 11:252-260. (Pubitemid 43316056)
8. Dick DM, Foroud T, Flury L, Bowman ES, Miller MJ, Rau NL, Moe PR, Samavedy N, El-Mallakh R, Manji H, Glitz DA, Meyer ET, Smiley C, Hahn R, Widmark C, McKinney R, Sutton L, Ballas C, Grice D, Berrettini W, Byerley W, Coryell W, DePaulo R, MacKinnon DF, Gershon ES, Kelsoe JR, McMahon FJ, McInnis M, Murphy DL, Reich T, Scheftner W, Nurnberger JI Jr. 2003. Genomewide linkage analyses of bipolar disorder: A new sample of 250 pedigrees from the national institute of mental health genetics initiative. Am J Hum Genet 73:107-114. (Pubitemid 36793784)
9. Faraone SV, Glatt SJ, Su J, Tsuang MT. 2004. Three potential susceptibility loci shown by a genome-wide scan for regions influencing the age at onset of mania. Am J Psychiatry 161:625-630. (Pubitemid 38445505)
10. Goldberg JF, Garno JL, Leon AC, Kocsis JH, Portera L. 1999. A history of substance abuse complicates remission from acute mania in bipolar disorder. J Clin Psychiatry 60:733-740.
11. Goodwin FK, Jamison KR. 2007. Manic-depressive illness: Bipolar disorders and recurrent depression. New York, NY:Oxford University Press. p 1262.
12. Hasin DS, Stinson FS, Ogburn E, Grant BF. 2007. Prevalence, correlates, disability, and comorbidity of DSM-IV alcohol abuse and dependence in the United States: Results from the national epidemiologic survey on alcohol and related conditions. Arch Gen Psychiatry 64:830-842. (Pubitemid 47026379)
13. Kelsoe JR. 2003. Arguments for the genetic basis of the bipolar spectrum. J Affect Disord 73:183-197.
14. Kong A, Cox NJ. 1997. Allele-sharing models: LOD scores and accurate linkage tests. Am J Hum Genet 61:1179-1188. (Pubitemid 27492328)
15. Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES. 1996. Parametric and nonparametric linkage analysis: A unified multipoint approach. Am J Hum Genet 58:1347-1363. (Pubitemid 26153846)
16. Lander E, Kruglyak L. 1995. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results. Nat Genet 11:241-247.
17. Leckman JF, Sholomskas D, Thompson WD, Belanger A, Weissman MM. 1982. Best estimate of lifetime psychiatric diagnosis: A methodological study. Arch Gen Psychiatry 39:879-883. (Pubitemid 12042853)
18. Lin PI, McInnis MG, Potash JB, Willour VL, Mackinnon DF, Miao K, Depaulo JR, Zandi PP. 2005. Assessment of the effect of age at onset on linkage to bipolar disorder: Evidence on chromosomes 18p and 21q. Am J Hum Genet 77:545-555.
19. MacKinnon DF, Xu J, McMahon FJ, Simpson SG, Stine OC, McInnis MG, DePaulo JR. 1998. Bipolar disorder and panic disorder in families: An analysis of chromosome 18 data. Am J Psychiatry 155:829-831. (Pubitemid 28252666)
20. McInnis MG, Dick DM, Willour VL, Avramopoulos D, MacKinnon DF, Simpson SG, Potash JB, Edenberg HJ, Bowman ES, McMahon FJ, Smiley C, Chellis JL, Huo Y, Diggs T, Meyer ET, Miller M, Matteini AT, Rau NL, DePaulo JR, Gershon ES, Badner JA, Rice JP, Goate AM, Detera- Wadleigh SD, Nurnberger JI, Reich T, Zandi PP, Foroud TM. 2003. Genome-wide scan and conditional analysis in bipolar disorder: Evidence for genomic interaction in the national institute of mental health genetics initiative bipolar pedigrees. Biol Psychiatry 54:1265-1273. (Pubitemid 37464872)
21. McKowen JW, Frye MA, Altshuler LL, Gitlin MJ. 2005. Patterns of alcohol consumption in bipolar patients comorbid for alcohol abuse or dependence. Bipolar Disord 7:377-381. (Pubitemid 41065239)
22. McQueen MB,Devlin B, Faraone SV, Nimgaonkar VL, Sklar P, Smoller JW, Abou Jamra R, Albus M, Bacanu SA, Baron M, Barrett TB, Berrettini W, Blacker D, Byerley W, Cichon S, Coryell W, Craddock N, Daly MJ, Depaulo JR, Edenberg HJ, Foroud T, Gill M, Gilliam TC, Hamshere M, Jones I, Jones L, Juo SH, Kelsoe JR, Lambert D, Lange C, Lerer B, Liu J, Maier W, Mackinnon JD, McInnis MG, McMahon FJ, Murphy DL, Nothen MM, Nurnberger JI, Pato CN, Pato MT, Potash JB, Propping P, Pulver AE, Rice JP, Rietschel M, Scheftner W, Schumacher J, Segurado R, Van Steen K, Xie W, Zandi PP, Laird NM. 2005. Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet 77:582-595. (Pubitemid 41361605)
23. Merikangas KR, Akiskal HS, Angst J, Greenberg PE, Hirschfeld RM, Petukhova M, Kessler RC. 2007. Lifetime and 12-month prevalence of bipolar spectrum disorder in the national comorbidity survey replication. Arch Gen Psychiatry 64:543-552. (Pubitemid 46718287)
24. Merikangas KR, Herrell R, Swendsen J, RosslerW,Ajdacic-Gross V, Angst J. 2008. Specificity of bipolar spectrum conditions in the comorbidity of mood and substance use disorders: Results from the Zurich cohort study. Arch Gen Psychiatry 65:47-52.
25. Nurnberger JI Jr, Blehar MC, Kaufmann CA, York-Cooler C, Simpson SG, Harkavy-Friedman J, Severe JB, Malaspina D, Reich T. 1994. Diagnostic interview for genetic studies. rationale, unique features, and training. NIMH genetics initiative. Arch Gen Psychiatry 51:849-859; discussion 863-864
26. Nurnberger JI Jr, Wiegand R, Bucholz K, O'Connor S, Meyer ET, Reich T, Rice J, Schuckit M, King L, Petti T, Bierut L, Hinrichs AL, Kuperman S, Hesselbrock V, Porjesz B. 2004. A family study of alcohol dependence: Coaggregation of multiple disorders in relatives of alcohol-dependent probands. Arch Gen Psychiatry 61:1246-1256. (Pubitemid 39602841)
27. Nurnberger JI Jr, Kuperman S, Flury-Wetherill L, Meyer ET, Lawson WB, Mackinnon DF. 2007. Genetics of comorbid mood disorder and alcohol dependence. J Dual Diagnosis 3:31-46. (Pubitemid 46953126)
28. Potash JB, Kane HS, Chiu YF, Simpson SG, MacKinnon DF, McInnis MG, McMahon FJ, DePaulo JR Jr. 2000. Attempted suicide and alcoholism in bipolar disorder: Clinical and familial relationships. Am J Psychiatry 157:2048-2050.
29. Potash JB, Zandi PP, Willour VL, Lan TH, Huo Y, Avramopoulos D, Shugart YY, MacKinnon DF, Simpson SG, McMahon FJ, DePaulo JR Jr, McInnis MG. 2003. Suggestive linkage to chromosomal regions 13q31 and 22q12 in families with psychotic bipolar disorder. Am J Psychiatry 160:680-686. (Pubitemid 41079600)
30. Potash JB, Toolan J, Steele J, Miller EB, Pearl J, Zandi PP, Schulze TG, Kassem L, Simpson SG, Lopez V, MacKinnon DF, McMahon FJ. 2007. The bipolar disorder phenome database: A resource for genetic studies. Am J Psychiatry 164:1229-1237. (Pubitemid 47292412)
31. Potash JB, Buervenich S, Cox NJ, Zandi PP, Akula N, Steele J, Rathe JA, Avramopoulos D, Detera-Wadleigh SD, Gershon ES, DePaulo JR Jr, Feinberg AP, McMahon FJ. 2008. Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: Association with HMG2L1 and TOM1. Am J Med Genet Part B 147B:59-67.
32. Prescott CA. 2001. The genetic epidemiology of alcoholism: Sex differences and future directions. In: Agarwal DP SH, editor. Alcohol in health and disease. New York and Basel:Marcel Dekker, Inc. pp 125-149.
33. Saunders EH, Scott LJ, McInnis MG, Burmeister M. 2008. Familiality and diagnostic patterns of subphenotypes in the national institutes of mental health bipolar sample. Am J Med Genet Part B 147B:18-26.
34. Schuckit MA, Smith TL, Danko GP, Bucholz KK, Reich T, Bierut L. 2001. Five-year clinical course associated with DSM-IV alcohol abuse or dependence in a large group of men and women. Am J Psychiatry 158:1084-1090. (Pubitemid 32623112)
35. Schulze TG, Ohlraun S, Czerski PM, Schumacher J, Kassem L, Deschner M, Gross M, Tullius M, Heidmann V, Kovalenko S, Jamra RA, Becker T, Leszczynska-Rodziewicz A, Hauser J, Illig T, Klopp N, Wellek S, Cichon S, HennFA,McMahonFJ, MaierW,Propping P, NothenMM,Rietschel M. 2005. Genotype-phenotype studies in bipolar disorder showing association between theDAOA/G30locus and persecutory delusions:Afirst step toward a molecular genetic classification of psychiatric phenotypes. Am J Psychiatry 162:2101-2108. (Pubitemid 41598264)
36. Schulze T, Hedeker D, Zandi P, Rietschel M, McMahon F. 2006. What is familial about familial bipolar disorder? Resemblance among relatives across a broad spectrum of phenotypic characteristics. Arch Gen Psychiatry 63:1368-1376. (Pubitemid 44878520)
37. Segurado R, Detera-Wadleigh SD, Levinson DF, Lewis CM, Gill M, Nurnberger JI Jr, Craddock N, DePaulo JR, Baron M, Gershon ES, Ekholm J, Cichon S, Turecki G, Claes S, Kelsoe JR, Schofield PR, Badenhop RF, Morissette J, Coon H, Blackwood D, McInnes LA, Foroud T, Edenberg HJ, Reich T, Rice JP, Goate A, McInnis MG, McMahon FJ, Badner JA, Goldin LR, Bennett P, Willour VL, Zandi PP, Liu J, Gilliam C, Juo SH, Berrettini WH, Yoshikawa T, Peltonen L, Lonnqvist J, Nothen MM, Schumacher J, Windemuth C, Rietschel M, Propping P, Maier W, Alda M, Grof P, Rouleau GA, Del-Favero J, Van Broeckhoven C, Mendlewicz J, Adolfsson R, Spence MA, Luebbert H, Adams LJ, Donald JA, Mitchell PB, Barden N, Shink E, Byerley W, Muir W, Visscher PM, Macgregor S, Gurling H, Kalsi G, McQuillin A, EscamillaMA,Reus VI, Leon P, Freimer NB, Ewald H, Kruse TA, Mors O, Radhakrishna U, Blouin JL, Antonarakis SE, Akarsu N. 2003. Genome scan meta-analysis of schizophrenia and bipolar disorder. Part III. Bipolar disorder. Am J Hum Genet 73:49-62. (Pubitemid 36793779)
38. Smoller JW, Finn CT. 2003. Family, twin, and adoption studies of bipolar disorder. Am J Med Genet Part C 123C:48-58. (Pubitemid 37356432)
39. Willour VL, Zandi PP, Badner JA, Steele J, Miao K, Lopez V, MacKinnon DF, Mondimore FM, Schweizer B, McInnis MG, Miller EB, Depaulo JR Jr, Gershon ES, McMahon FJ, Potash JB. 2007. Attempted suicide in bipolar disorder pedigrees: Evidence for linkage to 2p12. Biol Psychiatry 61:725-727. (Pubitemid 46343540)
40. Winokur G, Coryell W, Endicott J, Keller M, Akiskal H, Solomon D. 1996. Familial alcoholism in manic-depressive (bipolar) disease. Am J Med Genet 67:197-201. (Pubitemid 126467177)
41. Winokur G, Turvey C, Akiskal H, Coryell W, Solomon D, Leon A, Mueller T, Endicott J, Maser J, Keller M. 1998. Alcoholism and drug abuse in three groups-Bipolar I, unipolars and their acquaintances. J Affect Disord 50:81-89. (Pubitemid 28551777)
42. Zandi PP, Badner JA, Steele J, Willour VL, Miao K, MacKinnon DF, Mondimore FM, Schweizer B, McInnis MG, DePaulo JR Jr, Gershon E, McMahon FJ, Potash JB. 2007. Genome-wide linkage scan of 98 bipolar pedigrees and analysis of clinical covariates. Mol Psychiatry 12:630-639. (Pubitemid 46998258)