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Volumn 20, Issue 1, 2010, Pages 87-91
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Design and synthesis of a hybrid potentiator-corrector agonist of the cystic fibrosis mutant protein ΔF508-CFTR
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Author keywords
F508 CFTR; Correctors; Cystic fibrosis transmembrane conductance regulator protein (CFTR); Hybrids; Multi ligand drug; Potentiators
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Indexed keywords
BITHIAZOLE;
ETHYLENE GLYCOL;
MUTANT PROTEIN;
PHENYLGLYCINE;
PROTEIN DELTA F508;
PYRROLE DERIVATIVE;
TRANSMEMBRANE CONDUCTANCE REGULATOR;
UNCLASSIFIED DRUG;
ARTICLE;
BROMINATION;
DRUG ACTIVITY;
DRUG DESIGN;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HYDROLYSIS;
LUNG FIBROSIS;
STRUCTURE ACTIVITY RELATION;
CYSTIC FIBROSIS;
CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR;
DRUG DESIGN;
GLYCINE;
HUMANS;
ION CHANNEL GATING;
MUTATION;
PROTEIN FOLDING;
SMALL MOLECULE LIBRARIES;
STRUCTURE-ACTIVITY RELATIONSHIP;
THIAZOLES;
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EID: 72049120101
PISSN: 0960894X
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmcl.2009.11.020 Document Type: Article |
Times cited : (27)
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References (22)
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