메뉴 건너뛰기




Volumn 207, Issue 4, 2010, Pages 671-679

Administration of neurotoxic doses of MDMA reduces sensitivity to ethanol and increases GAT-1 immunoreactivity in mice striatum

Author keywords

Ecstasy; Ethanol; GABA accumulation; GABA transporter; Hypothermia; Neurotoxicity; Sedation

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; 4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOBUTYRIC ACID; ALCOHOL; CARRIER PROTEIN; GAMMA AMINOBUTYRIC ACID TRANSPORTER 1; UNCLASSIFIED DRUG;

EID: 72049110226     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-009-1699-9     Document Type: Article
Times cited : (5)

References (58)
  • 1
    • 0024419358 scopus 로고
    • A new alcohol antagonist: Phaclofen
    • Allan AM, Harris RA (1989) A new alcohol antagonist: phaclofen. Life Sci 45:1771-1779
    • (1989) Life Sci , vol.45 , pp. 1771-1779
    • Allan, A.M.1    Harris, R.A.2
  • 2
    • 33947104638 scopus 로고    scopus 로고
    • 1 receptor facilitation of depolarization-induced release of gamma-amino-butyric acid in rat striatum is mediated by the cAMP/PKA pathway and involves P/Q-type calcium channels
    • DOI 10.1002/syn.20372
    • Arias-Montaño JA, Floran B, Floran L, Aceves J, Young JM (2007) Dopamine D(1) receptor facilitation of depolarization-induced release of gamma-amino-butyric acid in rat striatum is mediated by the cAMP/PKA pathway and involves P/Q-type calcium channels. Synapse 61:310-319 (Pubitemid 46412171)
    • (2007) Synapse , vol.61 , Issue.5 , pp. 310-319
    • Arias-Montano, J.-A.1    Floran, B.2    Floran, L.3    Aceves, J.4    Young, J.M.5
  • 3
    • 9344236027 scopus 로고    scopus 로고
    • Ethanol potentiation of GABAergic synaptic transmission may be self-limiting: Role of presynaptic GABA(B) receptors
    • Ariwodola OJ, Weiner JL (2004) Ethanol potentiation of GABAergic synaptic transmission may be self-limiting: role of presynaptic GABA(B) receptors. J Neurosci 24:10679-10686
    • (2004) J Neurosci , vol.24 , pp. 10679-10686
    • Ariwodola, O.J.1    Weiner, J.L.2
  • 4
    • 0020041198 scopus 로고
    • The use of inhibitors of GABA-transaminase for the determination of GABA turnover in mouse brain regions: An evaluation of aminooxyacetic acid and gabaculine
    • Bernasconi R, Maitre L, Martin P, Raschdorf F (1982) The use of GABA-transaminase for the determination of GABA turnover in mouse brain regions: na evaluation of aminooxyacetic acid and gabaculine. J Neurochem 38:57-66 (Pubitemid 12189194)
    • (1982) Journal of Neurochemistry , vol.38 , Issue.1 , pp. 57-66
    • Bernasconi, R.1    Maitre, L.2    Martin, P.3    Raschdorf, F.4
  • 7
    • 0036315898 scopus 로고    scopus 로고
    • Studies, using in vivo microdialysis, on the effect of the dopamine uptake inhibitor GBR 12909 on 3,4-methylenedioxymethamphetamine ('ecstasy')-induced dopamine release and free radical formation in the mouse striatum
    • DOI 10.1046/j.1471-4159.2002.00879.x
    • Camarero J, Sanchez V, O'Shea E, Green AR, Colado MI (2002) Studies, using in vivo microdialysis, on the effect of the dopamine uptake inhibitor GBR 12909 on 3, 4-methylenedioxymethamphetamine ('ecstasy') - induced dopamine release and free radical formation in the mouse striatum. J Neurochem 81:961-972 (Pubitemid 34809278)
    • (2002) Journal of Neurochemistry , vol.81 , Issue.5 , pp. 961-972
    • Camarero, J.1    Sanchez, V.2    O'Shea, E.3    Green, A.R.4    Colado, M.I.5
  • 8
    • 1942425652 scopus 로고    scopus 로고
    • Alcohol Enhances GABAergic Transmission to Cerebellar Granule Cells via an Increase in Golgi Cell Excitability
    • DOI 10.1523/JNEUROSCI.0067-04.2004
    • Carta M, Mameli M, Valenzuela CF (2004) Alcohol enhances GABAergic transmission to cerebellar granule cells via an increase in Golgi cell excitability. J Neurosci 24:3746-3751 (Pubitemid 38509403)
    • (2004) Journal of Neuroscience , vol.24 , Issue.15 , pp. 3746-3751
    • Carta, M.1    Mameli, M.2    Valenzuela, C.F.3
  • 9
    • 0035679302 scopus 로고    scopus 로고
    • A study of the mechanisms involved in the neurotoxic action of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') on dopamine neurones in mouse brain
    • Colado MI, Camarero J, Mechan AO, Sanchez V, Esteban B, Elliott JM et al (2001) A study of the mechanisms involved in the neurotoxic action of 3, 4-methylenedioxymethamphetamine (MDMA, 'ecstasy') on dopamine neurones in mouse brain. Br J Pharmacol 134:1711-1723 (Pubitemid 34038105)
    • (2001) British Journal of Pharmacology , vol.134 , Issue.8 , pp. 1711-1723
    • Colado, M.I.1    Camarero, J.2    Mechan, A.O.3    Sanchez, V.4    Esteban, B.5    Elliott, J.M.6    Green, A.R.7
  • 11
    • 0028281897 scopus 로고
    • Tolerance to ethanol hypothermia in HOT and COLD mice
    • Crabbe JC (1994) Tolerance to ethanol hypothermia in HOT and COLD mice. Alcohol Clin Exp Res 18:42-46
    • (1994) Alcohol Clin Exp Res , vol.18 , pp. 42-46
    • Crabbe, J.C.1
  • 14
    • 23844475447 scopus 로고    scopus 로고
    • A conceptualization of integrated actions of ethanol contributing to its GABAmimetic profile: A commentary
    • Criswell HE, Breese GR (2005) A conceptualization of integrated actions of ethanol contributing to its GABAmimetic profile: a commentary. Neuropsychopharmacology 30:1407-1425
    • (2005) Neuropsychopharmacology , vol.30 , pp. 1407-1425
    • Criswell, H.E.1    Breese, G.R.2
  • 15
    • 0021987684 scopus 로고
    • GABA mediation of the central effects of acute and chronic ethanol in mice
    • Dar MS, Wooles WR (1985) GABA mediation of the central effects of acute and chronic ethanol in mice. Pharmacol Biochem Behav 22:77-84
    • (1985) Pharmacol Biochem Behav , vol.22 , pp. 77-84
    • Dar, M.S.1    Wooles, W.R.2
  • 16
    • 13444269027 scopus 로고    scopus 로고
    • A comparative study on the acute and long-term effects of MDMA and 3,4-dihydroxymethamphetamine (HHMA) on brain monoamine levels after i.p. or striatal administration in mice
    • DOI 10.1038/sj.bjp.0706071
    • Escobedo I, O'Shea E, Orio L, Sanchez V, Segura M, de la Torre R et al (2005) A comparative study on the acute and long-term effects of MDMA and 3, 4-dihydroxymethamphetamine (HHMA) on brain monoamine levels after i.p. or striatal administration in mice. Br J Pharmacol 144:231-241 (Pubitemid 40216121)
    • (2005) British Journal of Pharmacology , vol.144 , Issue.2 , pp. 231-241
    • Escobedo, I.1    O'Shea, E.2    Orio, L.3    Sanchez, V.4    Segura, M.5    De La Torre, R.6    Farre, M.7    Green, A.R.8    Colado, M.I.9
  • 18
    • 0020391538 scopus 로고
    • GABAergic modulation of ethanol-induced motor impairment
    • Frye GD, Breese GR (1982) GABAergic modulation of ethanol-induced motor impairment. J Pharmacol Exp Ther 223:750-756
    • (1982) J Pharmacol Exp Ther , vol.223 , pp. 750-756
    • Frye, G.D.1    Breese, G.R.2
  • 19
    • 0020555276 scopus 로고
    • Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: Blockade of audiogenic seizures but not forelimb tremors
    • Frye GD, McCown TJ, Breese GR (1983) Differential sensitivity of ethanol withdrawal signs in the rat to gamma-aminobutyric acid (GABA)mimetics: blockade of audiogenic seizures but not forelimb tremors. J Pharmacol Exp Ther 226:720-725
    • (1983) J Pharmacol Exp Ther , vol.226 , pp. 720-725
    • Frye, G.D.1    McCown, T.J.2    Breese, G.R.3
  • 20
    • 0031578748 scopus 로고    scopus 로고
    • The effect of GABAergic system activity on hyperthermia-induced seizures in rats
    • DOI 10.1016/S0165-3806(97)00157-0, PII S0165380697001570
    • Fukuda M, Morimoto T, Nagao H, Kida K (1997) The effect of GABAergic system activity on hyperthermia-induced seizures in rats. Brain Res Dev Brain Res 104:197-199 (Pubitemid 28035728)
    • (1997) Developmental Brain Research , vol.104 , Issue.1-2 , pp. 197-199
    • Fukuda, M.1    Morimoto, T.2    Nagao, H.3    Kida, K.4
  • 21
    • 0019973185 scopus 로고
    • GABA turnover in mouse brain: Agreement between the rate of GABA accumulation after aminooxyacetic acid and the rate of disappearance after 3-mercaptopropionic acid
    • Gomes C, Trolin G (1982) GABA turnover in mouse brain: agreement between the rate of GABA accumulation after aminooxyacetic acid and the rate of disappearance after 3-mercaptopropionic acid. J Neural Transm 54:265-274
    • (1982) J Neural Transm , vol.54 , pp. 265-274
    • Gomes, C.1    Trolin, G.2
  • 22
    • 36348951506 scopus 로고    scopus 로고
    • Early loss of dopaminergic terminals in striosomes after MDMA administration to mice
    • DOI 10.1002/syn.20466
    • Granado N, Escobedo I, O'Shea E, Colado I, Moratalla R (2008a) Early loss of dopaminergic terminals in striosomes after MDMA administration to mice. Synapse 62:80-84 (Pubitemid 350156147)
    • (2008) Synapse , vol.62 , Issue.1 , pp. 80-84
    • Granado, N.1    Escobedo, I.2    O'Shea, E.3    Colado, Ma.I.4    Moratalla, R.5
  • 23
    • 54349116574 scopus 로고    scopus 로고
    • Persistent MDMA-induced dopaminergic neurotoxicity in the striatum and substantia nigra of mice
    • Granado N, O'Shea E, Bove J, Vila M, Colado MI, Moratalla R (2008b) Persistent MDMA-induced dopaminergic neurotoxicity in the striatum and substantia nigra of mice. J Neurochem 107:1102-1112
    • (2008) J Neurochem , vol.107 , pp. 1102-1112
    • Granado, N.1    O'Shea, E.2    Bove, J.3    Vila, M.4    Colado, M.I.5    Moratalla, R.6
  • 24
    • 0041466261 scopus 로고    scopus 로고
    • The pharmacology and clinical pharmacology of 3,4- methylenedioxymethamphetamine (MDMA, "ecstasy")
    • DOI 10.1124/pr.55.3.3
    • Green AR, Mechan AO, Elliott JM, O'Shea E, Colado MI (2003) The pharmacology and clinical pharmacology of 3, 4-methylenedioxymethamphetamine (MDMA, "ecstasy"). Pharmacol Rev 55:463-508 (Pubitemid 37013213)
    • (2003) Pharmacological Reviews , vol.55 , Issue.3 , pp. 463-508
    • Green, A.R.1    Mechan, A.O.2    Elliott, J.M.3    O'Shea, E.4    Colado, M.I.5
  • 25
    • 0028999763 scopus 로고
    • Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors
    • Harris RA, McQuilkin SJ, Paylor R, Abeliovich A, Tonegawa S, Wehner JM (1995) Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors. Proc Natl Acad Sci U S A 92:3658-3662
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 3658-3662
    • Harris, R.A.1    McQuilkin, S.J.2    Paylor, R.3    Abeliovich, A.4    Tonegawa, S.5    Wehner, J.M.6
  • 26
    • 0024786578 scopus 로고
    • GABA turnover in the brain of rat lines developed for differential ethanol-induced motor impairment
    • Hellewuo K, Kiianmaa K (1989) GABA turnover in the brain of rat lines developed for differential ethanol-induced motor impairment. Pharmacol Biochem Behav 34:905-909
    • (1989) Pharmacol Biochem Behav , vol.34 , pp. 905-909
    • Hellewuo, K.1    Kiianmaa, K.2
  • 28
    • 0021697277 scopus 로고
    • Ethanol-induced inhibition of GABA release from LS and SS mouse brain slices
    • Howerton TC, Collins AC (1984) Ethanol-induced inhibition of GABA release from LS and SS mouse brain slices. Alcohol 1:471-477
    • (1984) Alcohol , vol.1 , pp. 471-477
    • Howerton, T.C.1    Collins, A.C.2
  • 29
    • 1642482428 scopus 로고    scopus 로고
    • Up-regulation of gamma-aminobutyric acid transporter I mediates ethanol sensitivity in mice
    • DOI 10.1016/j.neuroscience.2003.11.018
    • Hu JH, Ma YH, Yang N, Mei ZT, Zhang MH, Fei J, Guo LH (2004) Up-regulation of gamma-aminobutyric acid transporter I mediates ethanol sensitivity in mice. Neuroscience 123:807-812 (Pubitemid 38130091)
    • (2004) Neuroscience , vol.123 , Issue.4 , pp. 807-812
    • Hu, J.-H.1    Ma, Y.-H.2    Yang, N.3    Mei, Z.-T.4    Zhang, M.-H.5    Fei, J.6    Guo, L.-H.7
  • 30
    • 0018165678 scopus 로고
    • GABA and benzodiazepine receptors
    • Iversen LL (1978) GABA and benzodiazepine receptors. Nature 275:477
    • (1978) Nature , vol.275 , pp. 477
    • Iversen, L.L.1
  • 32
    • 4644342311 scopus 로고    scopus 로고
    • A role for GABA mechanisms in the motivational effects of alcohol
    • Koob GF (2004) A role for GABA mechanisms in the motivational effects of alcohol. Biochem Pharmacol 68:1515-1525
    • (2004) Biochem Pharmacol , vol.68 , pp. 1515-1525
    • Koob, G.F.1
  • 33
    • 0019979756 scopus 로고
    • Effects of GABAergic agonists and antagonists on various ethanol-induced behavioral changes
    • DOI 10.1007/BF00470592
    • Liljequist S, Engel J (1982) Effects of GABAergic agonists and antagonists on various ethanol-induced behavioral changes. Psychopharmacology 78:71-75 (Pubitemid 12036025)
    • (1982) Psychopharmacology , vol.78 , Issue.1 , pp. 71-75
    • Liljequist, S.1    Engel, J.2
  • 34
    • 0023722481 scopus 로고
    • Differences between rats and mice in MDMA (methylenedioxymethylamphetamine) neurotoxicity
    • DOI 10.1016/0014-2999(88)90717-0
    • Logan BJ, Laverty R, Sanderson WD, Yee YB (1988) Differences between rats and mice in MDMA (methylenedioxymethylamphetamine) neurotoxicity. Eur J Pharmacol 152:227-234 (Pubitemid 18199600)
    • (1988) European Journal of Pharmacology , vol.152 , Issue.3 , pp. 227-234
    • Logan, B.J.1    Laverty, R.2    Sanderson, W.D.3    Yee, Y.B.4
  • 36
    • 0030832634 scopus 로고    scopus 로고
    • Differential toxic effects of methamphetamine (METH) and methylenedioxymethamphetamine (MDMA) in multidrug-resistant (mdr1a) knockout mice
    • DOI 10.1016/S0006-8993(97)00754-3, PII S0006899397007543
    • Mann H, Ladenheim B, Hirata H, Moran TH, Cadet JL (1997) Differential toxic effects of methamphetamine (METH) and methylenedioxymethamphetamine (MDMA) in multidrug-resistant (mdr1a) knockout mice. Brain Res 769:340-346 (Pubitemid 27461470)
    • (1997) Brain Research , vol.769 , Issue.2 , pp. 340-346
    • Mann, H.1    Ladenheim, B.2    Hirata, H.3    Moran, T.H.4    Cadet, J.L.5
  • 37
    • 0020539998 scopus 로고
    • Behavioral evidence for the involvement of gamma-aminobutyric acid in the actions of ethanol
    • Martz A, Deitrich RA, Harris RA (1983) Behavioral evidence for the involvement of gamma-aminobutyric acid in the actions of ethanol. Eur J Pharmacol 89:53-62 (Pubitemid 13133369)
    • (1983) European Journal of Pharmacology , vol.89 , Issue.1-2 , pp. 53-62
    • Martz, A.1    Deitrich, R.2    Harris, R.A.3
  • 38
    • 0036897362 scopus 로고    scopus 로고
    • 2A receptors
    • Naassila M, Ledent C, Daoust M (2002) Low ethanol sensitivity and increased ethanol consumption in mice lacking adenosine A2A receptors. J Neurosci 22:10487-10493 (Pubitemid 35416885)
    • (2002) Journal of Neuroscience , vol.22 , Issue.23 , pp. 10487-10493
    • Naassila, M.1    Ledent, C.2    Daoust, M.3
  • 39
    • 0347480441 scopus 로고    scopus 로고
    • Decreased alcohol self-administration and increased alcohol sensitivity and withdrawal in CB1 receptor knockout mice
    • DOI 10.1016/j.neuropharm.2003.09.002
    • Naassila M, Pierrefiche O, Ledent C, Daoust M (2004) Decreased alcohol self-administration and increased alcohol sensitivity and withdrawal in CB1 receptor knockout mice. Neuropharmacology 46:243-253 (Pubitemid 37532832)
    • (2004) Neuropharmacology , vol.46 , Issue.2 , pp. 243-253
    • Naassila, M.1    Pierrefiche, O.2    Ledent, C.3    Daoust, M.4
  • 41
    • 0027931499 scopus 로고
    • Neurotoxicity profiles of substituted amphetamines in the C57BL/6 J mouse
    • O'Callaghan JP, Miller DB (1994) Neurotoxicity profiles of substituted amphetamines in the C57BL/6 J mouse. J Pharmacol Exp Ther 270:741-751
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 741-751
    • O'Callaghan, J.P.1    Miller, D.B.2
  • 42
    • 0035227059 scopus 로고    scopus 로고
    • Effect of GBR 12909 and fluoxetine on the acute and long term changes induced by MDMA ('ecstasy') on the 5-HT and dopamine concentrations in mouse brain
    • PII S0028390800001064
    • O'Shea E, Esteban B, Camarero J, Green AR, Colado MI (2001) Effect of GBR 12909 and fluoxetine on the acute and long term changes induced by MDMA ('ecstasy') on the 5-HT and dopamine concentrations in mouse brain. Neuropharmacology 40:65-74 (Pubitemid 33779801)
    • (2001) Neuropharmacology , vol.40 , Issue.1 , pp. 65-74
    • O'Shea, E.1    Esteban, B.2    Camarero, J.3    Green, A.R.4    Colado, M.I.5
  • 44
    • 0141676728 scopus 로고    scopus 로고
    • Dynamic equilibrium of neurotransmitter transporters: Not just for reuptake anymore
    • Richerson GB, Wu Y (2003) Dynamic equilibrium of neurotransmitter transporters: not just for reuptake anymore. J Neurophysiol 90:1363-1374
    • (2003) J Neurophysiol , vol.90 , pp. 1363-1374
    • Richerson, G.B.1    Wu, Y.2
  • 45
    • 8544225739 scopus 로고    scopus 로고
    • Increased GABA release in the central amygdala of ethanol-dependent rats
    • DOI 10.1523/JNEUROSCI.3004-04.2004
    • Roberto M, Madamba SG, Stouffer DG, Parsons LH, Siggins GR (2004) Increased GABA release in the central amygdala of ethanol-dependent rats. J Neurosci 24:10159-10166 (Pubitemid 39492041)
    • (2004) Journal of Neuroscience , vol.24 , Issue.45 , pp. 10159-10166
    • Roberto, M.1    Madamba, S.G.2    Stouffer, D.G.3    Parsons, L.H.4    Siggins, G.R.5
  • 47
    • 0023719331 scopus 로고
    • Reactions to alcohol in sons of alcoholics and controls
    • Schuckit MA (1988) Reactions to alcohol in sons of alcoholics and controls. Alcohol Clin Exp Res 12:465-470
    • (1988) Alcohol Clin Exp Res , vol.12 , pp. 465-470
    • Schuckit, M.A.1
  • 48
    • 0028107317 scopus 로고
    • Low level of response to alcohol as a predictor of future alcoholism
    • Schuckit MA (1994) Low level of response to alcohol as a predictor of future alcoholism. Am J Psychiatry 151:184-189
    • (1994) Am J Psychiatry , vol.151 , pp. 184-189
    • Schuckit, M.A.1
  • 49
    • 0029866658 scopus 로고    scopus 로고
    • An 8-year follow-up of 450 sons of alcoholic and control subjects
    • Schuckit MA, Smith TL (1996) An 8-year follow-up of 450 sons of alcoholic and control subjects. Arch Gen Psychiatry 53:202-210
    • (1996) Arch Gen Psychiatry , vol.53 , pp. 202-210
    • Schuckit, M.A.1    Smith, T.L.2
  • 50
    • 0642308240 scopus 로고    scopus 로고
    • Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge
    • DOI 10.1038/sj.npp.1300247
    • Segal DS, Kuczenski R, O'Neil ML, Melega WP, Cho AK (2003) Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge. Neuropsychopharmacology 28:1730-1740 (Pubitemid 41070838)
    • (2003) Neuropsychopharmacology , vol.28 , Issue.10 , pp. 1730-1740
    • Segal, D.S.1    Kuczenski, R.2    O'Neil, M.L.3    Melega, W.P.4    Cho, A.K.5
  • 51
    • 0019278544 scopus 로고
    • Electrophysiological correlates of ethanol-induced sedation in differentially sensitive lines of mice
    • Sorensen S, Palmer M, Dunwiddie T, Hoffer B (1980) Electrophysiological correlates of ethanol-induced sedation in differentially sensitive lines of mice. Science 210:1143-1145 (Pubitemid 11166026)
    • (1980) Science , vol.210 , Issue.4474 , pp. 1143-1145
    • Sorensen, S.1    Palmer, M.2    Dunwiddie, T.3    Hoffer, B.4
  • 53
    • 0023522125 scopus 로고
    • Differences in the central serotoneric effects of methylenedioxymethamphetamine (MDMA) in mice and rats
    • DOI 10.1016/0028-3908(87)90017-7
    • Stone DM, Hanson GR, Gibb JW (1987) Differences in the central serotonergic effects of methylenedioxymethamphetamine (MDMA) in mice and rats. Neuropharmacology 26:1657-1661 (Pubitemid 18008368)
    • (1987) Neuropharmacology , vol.26 , Issue.11 , pp. 1657-1661
    • Stone, D.M.1    Hanson, G.R.2    Gibb, J.W.3
  • 54
    • 0019216193 scopus 로고
    • Ethanol and other CNS depressants decrease GABA synthesis in mouse cerebral cortex and cerebellum in vivo
    • DOI 10.1016/0024-3205(80)90026-0
    • Supavilai P, Karobath M (1980) Ethanol and other CNS depressants decrease GABA synthesis in mouse cerebral cortex and cerebellum in vivo. Life Sci 27:1035-1040 (Pubitemid 11252512)
    • (1980) Life Sciences , vol.27 , Issue.12 , pp. 1035-1040
    • Supavilai, P.1    Karobath, M.2
  • 55
    • 0021752510 scopus 로고
    • Studies on tolerance development in inbred and heterogeneous stock National Institutes of Health rats
    • Tabakoff B, Culp SG (1984) Studies on tolerance development in inbred and heterogeneous stock National Institutes of Health rats. Alcohol Clin Exp Res 8:495-499 (Pubitemid 15206895)
    • (1984) Alcoholism: Clinical and Experimental Research , vol.8 , Issue.5 , pp. 495-499
    • Tabakoff, B.1    Culp, S.G.2
  • 57
    • 0019274475 scopus 로고
    • Effect of acute and chronic ethanol treatment on gamma-aminobutyric acid levels and on aminooxyacetic acid-induced GABA accumulation
    • Wixon HN, Hunt WA (1980) Effect of acute and chronic ethanol treatment on gamma-aminobutyric acid levels and on aminooxyacetic acid-induced GABA accumulation. Subst Alcohol Actions Misuse 1:481-491 (Pubitemid 11127052)
    • (1980) Substance and Alcohol Actions/Misuse , vol.1 , Issue.5-6 , pp. 481-491
    • Wixon, H.N.1    Hunt, W.A.2
  • 58
    • 46549083590 scopus 로고    scopus 로고
    • Time-course of SKF-81297-induced increase in glutamic acid decarboxylase 65 and 67 mRNA levels in striatonigral neurons and decrease in GABA(A) receptor alpha1 subunit mRNA levels in the substantia nigra, pars reticulata, in adult rats with a unilateral 6-hydroxydopamine lesion
    • Yamamoto N, Soghomonian JJ (2008) Time-course of SKF-81297-induced increase in glutamic acid decarboxylase 65 and 67 mRNA levels in striatonigral neurons and decrease in GABA(A) receptor alpha1 subunit mRNA levels in the substantia nigra, pars reticulata, in adult rats with a unilateral 6-hydroxydopamine lesion. Neuroscience 154:1088-1099
    • (2008) Neuroscience , vol.154 , pp. 1088-1099
    • Yamamoto, N.1    Soghomonian, J.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.