Recovery of airway protective behaviors after spinal cord injury

Respiratory Physiology and Neurobiology

Volumn 169, Issue 2, 2009, Pages 150-156

  Bolser, Donald C ^a   Jefferson, Stephanie C ^a,b   Rose, Melanie J ^a   Tester, Nicole J ^a,b   Reier, Paul J ^a   Fuller, David D ^a   Davenport, Paul W ^a,b   Howland, Dena R ^a,b  

^a UNIVERSITY OF FLORIDA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Augmented breath, Control of breathing; Cough; Premotor; Spinal cord injury

Indexed keywords

AIRWAY; ARTICLE; BREATHING; BREATHING MECHANICS; BREATHING MUSCLE; COMPENSATION; CONVALESCENCE; COUGHING; EXPIRATORY FLOW; FUNCTIONAL STATUS; HUMAN; INTERNEURON; MOTOR PERFORMANCE; NERVE CELL; NERVE FIBER; NONHUMAN; PLASTICITY; PREMOTOR CORTEX; PRIORITY JOURNAL; REHABILITATION; SIGHING; SPINAL CORD INJURY; THORACIC SPINAL CORD;

AIRWAY REMODELING; ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; RECOVERY OF FUNCTION; RESPIRATORY MUSCLES; RESPIRATORY PARALYSIS; SPINAL CORD; SPINAL CORD INJURIES; THORACIC VERTEBRAE;

EID: 72049108085     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2009.07.018     Document Type: Article

References (75)

1. Baekey D.M., Morris K.F., Gestreau C., Li Z., Lindsey B.G., and Shannon R. Medullary respiratory neurones and control of laryngeal motoneurones during fictive eupnoea and cough in the cat. J. Physiol. 534 (2001) 565-581
2. Basser P.J., McMahon T.A., and Griffith P. The mechanism of mucus clearance in cough. J. Biomech. Eng. 111 (1989) 288-297
3. Bell H.J., Ferguson C., Kehoe V., and Haouzi P. Hypocapnia increases the prevalence of hypoxia-induced augmented breaths. Am. J. Physiol. Regul. Integr. Comp. Physiol. 296 (2009) R334-344
4. Billig I., Card J.P., and Yates B.J. Neurochemical phenotypes of MRF neurons influencing diaphragm and rectus abdominis activity. J. Appl. Physiol. 94 (2003) 391-398
5. Bolser D.C. Fictive cough in the cat. J. Appl. Physiol. 71 (1991) 2325-2331
6. Bolser D.C., and DeGennaro F.C. Effect of codeine on the inspiratory and expiratory burst pattern during fictive cough in cats. Brain Res. 662 (1994) 25-30
7. Bolser D.C., Reier P.J., and Davenport P.W. Responses of the anterolateral abdominal muscles during cough and expiratory threshold loading in the cat. J. Appl. Physiol. 88 (2000) 1207-1214
8. Brown R., DiMarco A.F., Hoit J.D., and Garshick E. Respiratory dysfunction and management in spinal cord injury. Respir. Care 51 (2006) 853-868 (discussion 869-870)
9. Cameron W.E., Averill D.B., and Berger A.J. Morphology of cat phrenic motoneurons as revealed by intracellular injection of horseradish peroxidase. J. Comp. Neurol. 219 (1983) 70-80
10. Cherniack N.S., von Euler C., Glogowska M., and Homma I. Characteristics and rate of occurrence of spontaneous and provoked augmented breaths. Acta Physiol. Scand. 111 (1981) 349-360
11. Cohen M.I., Feldman J.L., and Sommer D. Caudal medullary expiratory neurone and internal intercostal nerve discharges in the cat: effects of lung inflation. J. Physiol. 368 (1985) 147-178
12. Collazos-Castro J.E., Soto V.M., Gutierrez-Davila M., and Nieto-Sampedro M. Motoneuron loss associated with chronic locomotion impairments after spinal cord contusion in the rat. J. Neurotrauma 22 (2005) 544-558
13. Davis J.N., and Plum F. Separation of descending spinal pathways to respiratory motoneurons. Exp. Neurol. 34 (1972) 78-94
14. De Troyer A., Estenne M., Ninane V., Van Gansbeke D., and Gorini M. Transversus abdominis muscle function in humans. J. Appl. Physiol. 68 (1990) 1010-1016
15. De Troyer A., Estenne M., and Vincken W. Rib cage motion and muscle use in high tetraplegics. Am. Rev. Respir. Dis. 133 (1986) 1115-1119
16. De Troyer A., Sampson M., Sigrist S., and Kelly S. How the abdominal muscles act on the rib cage. J. Appl. Physiol. 54 (1983) 465-469
17. Dicpinigaitis P.V., Spungen A.M., Bauman W.A., Absgarten A., and Almenoff P.L. Bronchial hyperresponsiveness after cervical spinal cord injury. Chest 105 (1994) 1073-1076
18. DiMarco A.F., Romaniuk J.R., and Supinski G.S. Electrical activation of the expiratory muscles to restore cough. Am. J. Respir. Crit. Care Med. 151 (1995) 1466-1471
19. Engelhorn R., and Weller E. Central representation of cough effecting afferent impulses in the medulla oblongata in the cat. Pflugers Arch. Gesamte Physiol. Menschen Tiere 284 (1965) 224-239
20. Estenne M., and De Troyer A. The effects of tetraplegia on chest wall statics. Am. Rev. Respir. Dis. 134 (1986) 121-124
21. Estenne M., and De Troyer A. Cough in tetraplegic subjects: an active process. Ann. Intern. Med. 112 (1990) 22-28
22. Estenne M., and Gorini M. Action of the diaphragm during cough in tetraplegic subjects. J. Appl. Physiol. 72 (1992) 1074-1080
23. Evans H., and Christensen G.C. Miller's Anatomy of the Dog (1979), W.B Saunders, Philadelphia
24. Farkas G.A., Schroeder M.A., and De Troyer A. Effect of midline laparotomy on the cough reflex in dogs. Neurosci. Lett. 107 (1989) 120-124
25. Feldman J.L. Neurophysiology of breathing in mammals. Handbook of Physiology. The Nervous System. Intrinsic Regulatory Systems of the Brain (1986), American Physiological Society, Bethesda pp. 463-524
26. Floyd W.F., and Silver P.H. Electromyographic study of patterns of activity of the anterior abdominal wall muscles in man. J. Anat. 84 (1950) 132-145
27. Ford T.W., Vaughan C.W., and Kirkwood P.A. Changes in the distribution of synaptic potentials from bulbospinal neurones following axotomy in cat thoracic spinal cord. J. Physiol. 524 Pt 1 (2000) 163-178
28. Fuller D.D., Doperalski N.J., Dougherty B.J., Sandhu M.S., Bolser D.C., and Reier P.J. Modest spontaneous recovery of ventilation following chronic high cervical hemisection in rats. Exp. Neurol. 211 (2008) 97-106
29. Glogowska M., Richardson P.S., Widdicombe J.G., and Winning A.J. The role of the vagus nerves, peripheral chemoreceptors and other afferent pathways in the genesis of augmented breaths in cats and rabbits. Respir. Physiol. 16 (1972) 179-196
30. Golder F.J., Davenport P.W., Johnson R.D., Reier P.J., and Bolser D.C. Augmented breath phase volume and timing relationships in the anesthetized rat. Neurosci. Lett. 373 (2005) 89-93
31. Goshgarian H.G., and Rafols J.A. The phrenic nucleus of the albino rat: a correlative HRP and Golgi study. J. Comp. Neurol. 201 (1981) 441-456
32. Hayes K.C., and Kakulas B.A. Neuropathology of human spinal cord injury sustained in sports-related activities. J. Neurotrauma 14 (1997) 235-248
33. Holstege G., van Neerven J., and Evertse F. Spinal cord location of the motoneurons innervating the abdominal, cutaneous maximus, latissimus dorsi and longissimus dorsi muscles in the cat. Exp. Brain Res. 67 (1987) 179-194
34. Jaeger R.J., Turba R.M., Yarkony G.M., and Roth E.J. Cough in spinal cord injured patients: comparison of three methods to produce cough. Arch. Phys. Med. Rehabil. 74 (1993) 1358-1361
35. Jakus J., Tomori Z., and Stransky A. Activity of bulbar respiratory neurones during cough and other respiratory tract reflexes in cats. Physiol. Bohemoslov. 34 (1985) 127-136
36. Jefferson S.C., Rose M.J., Tester N.J., Blum A.E., Bolser D.C., and Howland D.R. Influence of chronic T10 spinal hemisection on the cough reflex in cats: functional manifestations of crossed spinal pathways. FASEB J. 20 (2006) A1213
37. Johnson M.A., Polgar J., Weightman D., and Appleton D. Data on the distribution of fibre types in thirty-six human muscles. An autopsy study. J. Neurol. Sci. 18 (1973) 111-129
38. Kirkwood P.A. Synaptic excitation in the thoracic spinal cord from expiratory bulbospinal neurones in the cat. J. Physiol. 484 Pt 1 (1995) 201-225
39. Kirkwood P.A., Munson J.B., Sears T.A., and Westgaard R.H. Respiratory interneurones in the thoracic spinal cord of the cat. J. Physiol. 395 (1988) 161-192
40. Kirkwood P.A., Schmid K., Otto M., and Sears T.A. Focal blockade of single unit synaptic transmission by iontophoresis of antagonists. Neuroreport 2 (1991) 185-188
41. Kirkwood P.A., Schmid K., and Sears T.A. Functional identities of thoracic respiratory interneurones in the cat. J. Physiol. 461 (1993) 667-687
42. Kondo T., Bishop B., and Shaw C.F. Phasic stretch reflex of the abdominal muscles. Exp. Neurol. 94 (1986) 120-140
43. Korpas J., and Tomori Z. Cough and Other Respiratory Reflexes (1979), S. Karger, Basel, New York
44. Lane M.A., White T.E., Coutts M.A., Jones A.L., Sandhu M.S., Bloom D.C., Bolser D.C., Yates B.J., Fuller D.D., and Reier P.J. Cervical prephrenic interneurons in the normal and lesioned spinal cord of the adult rat. J. Comp. Neurol. 511 (2008) 692-709
45. Langlands J. The dynamics of cough in health and in chronic bronchitis. Thorax 22 (1967) 88-96
46. Leith D.E., Butler J.P., Sneddon S.L., and Brain J.D. Cough. Handbook of Physiology. The Respiratory System, V. III. Mechanics of Breathing, Part I (1986), American Physiological Society, Bethesda pp. 315-336
47. Lipski J., Zhang X., Kruszewska B., and Kanjhan R. Morphological study of long axonal projections of ventral medullary inspiratory neurons in the rat. Brain Res. 640 (1994) 171-184
48. Loveridge B., Sanii R., and Dubo H.I. Breathing pattern adjustments during the first year following cervical spinal cord injury. Paraplegia 30 (1992) 479-488
49. Loveridge B.M., and Dubo H.I. Breathing pattern in chronic quadriplegia. Arch. Phys. Med. Rehabil. 71 (1990) 495-499
50. McKinley W., Santos K., Meade M., and Brooke K. Incidence and outcomes of spinal cord injury clinical syndromes. J. Spinal Cord Med. 30 (2007) 215-224
51. Merrill E.G., and Lipski J. Inputs to intercostal motoneurons from ventrolateral medullary respiratory neurons in the cat. J. Neurophysiol. 57 (1987) 1837-1853
52. Mier A., Brophy C., Estenne M., Moxham J., Green M., and De Troyer A. Action of abdominal muscles on rib cage in humans. J. Appl. Physiol. 58 (1985) 1438-1443
53. Miller A.D. Localization of motoneurons innervating individual abdominal muscles of the cat. J. Comp. Neurol. 256 (1987) 600-606
54. Mills C.D., Hains B.C., Johnson K.M., and Hulsebosch C.E. Strain and model differences in behavioral outcomes after spinal cord injury in rat. J. Neurotrauma 18 (2001) 743-756
55. Moore B.J., Verburgt L.M., King G.G., and Pare P.D. The effect of deep inspiration on methacholine dose-response curves in normal subjects. Am. J. Respir. Crit. Care Med. 156 (1997) 1278-1281
56. Reier P.J., Golder F.J., Bolser D.C., Hubscher C., Johnson R., Schrimsher G.W., and Velardo M.J. Grey matter repair in the cervical spinal cord. In: Mckerracher L., Doucet G., and Rossignol S. (Eds). Spinal Cord Trauma: Regeneration, Neural Repair and Functional Recovery (2002), Elsevier 49-70
57. Routal R.V., and Pal G.P. Location of the phrenic nucleus in the human spinal cord. J. Anat. 195 Pt 4 (1999) 617-621
58. Russell J.A., Bishop B.P., and Hyatt R.E. Discharge of abdominal muscle alpha and gamma motoneurons during expiratory loading in cats. Exp. Neurol. 97 (1987) 179-192
59. Saywell S.A., Anissimova N.P., Ford T.W., Meehan C.F., and Kirkwood P.A. The respiratory drive to thoracic motoneurones in the cat and its relation to the connections from expiratory bulbospinal neurones. J. Physiol. 579 (2007) 765-782
60. Schilero G.J., Spungen A.M., Bauman W.A., Radulovic M., and Lesser M. Pulmonary function and spinal cord injury. Respir. Physiol. Neurobiol. 166 (2009) 129-141
61. Schmid K., Kirkwood P.A., Munson J.B., Shen E., and Sears T.A. Contralateral projections of thoracic respiratory interneurones in the cat. J. Physiol. 461 (1993) 647-665
62. Schmitt J., Midha M., and McKenzie N. Medical complications of spinal cord disease. Neurol. Clin. 9 (1991) 779-795
63. Schrimsher G.W., and Reier P.J. Forelimb motor performance following cervical spinal cord contusion injury in the rat. Exp. Neurol. 117 (1992) 287-298
64. Sekizawa S., Chen C.Y., Bechtold A.G., Tabor J.M., Bric J.M., Pinkerton K.E., Joad J.P., and Bonham A.C. Extended secondhand tobacco smoke exposure induces plasticity in nucleus tractus solitarius second-order lung afferent neurons in young guinea pigs. Eur. J. Neurosci. 28 (2008) 771-781
65. Shannon R., Baekey D.M., Morris K.F., and Lindsey B.G. Brainstem respiratory networks and cough. Pulm. Pharmacol. 9 (1996) 343-347
66. Shannon R., Baekey D.M., Morris K.F., and Lindsey B.G. Ventrolateral medullary respiratory network and a model of cough motor pattern generation. J. Appl. Physiol. 84 (1998) 2020-2035
67. Shannon R., Baekey D.M., Morris K.F., Nuding S.C., Segers L.S., and Lindsey B.G. Production of reflex cough by brainstem respiratory networks. Pulm. Pharmacol. Ther. 17 (2004) 369-376
68. Siebens A.A., Kirby N.A., and Poulos D.A. Cough following transection of spinal cord at C-6. Arch. Phys. Med. Rehabil. 45 (1964) 1-8
69. Sieck G.C., and Fournier M. Diaphragm motor unit recruitment during ventilatory and nonventilatory behaviors. J. Appl. Physiol. 66 (1989) 2539-2545
70. Skloot G., Permutt S., and Togias A. Airway hyperresponsiveness in asthma: a problem of limited smooth muscle relaxation with inspiration. J. Clin. Invest. 96 (1995) 2393-2403
71. Strohl K.P., Mead J., Banzett R.B., Loring S.H., and Kosch P.C. Regional differences in abdominal muscle activity during various maneuvers in humans. J. Appl. Physiol. 51 (1981) 1471-1476
72. Tomori Z., and Widdicombe J.G. Muscular, bronchomotor and cardiovascular reflexes elicited by mechanical stimulation of the respiratory tract. J. Physiol. 200 (1969) 25-49
73. van Lunteren E., Daniels R., Deal Jr. E.C., and Haxhiu M.A. Role of costal and crural diaphragm and parasternal intercostals during coughing in cats. J. Appl. Physiol. 66 (1989) 135-141
74. van Lunteren E., Haxhiu M.A., Cherniack N.S., and Arnold J.S. Role of triangularis sterni during coughing and sneezing in dogs. J. Appl. Physiol. 65 (1988) 2440-2445
75. van Lunteren E., Prabhakar N.R., Cherniack N.S., Haxhiu M.A., and Dick T.E. Inhibition of expiratory muscle EMG and motor unit activity during augmented breaths in cats. Respir. Physiol. 72 (1988) 303-314