-
1
-
-
43049122505
-
11β-Hydroxysteroid dehydrogenase type 1 and obesity
-
Morton N.M., and Seckl J.R. 11β-Hydroxysteroid dehydrogenase type 1 and obesity. Front Horm Res 36 (2008) 146-164
-
(2008)
Front Horm Res
, vol.36
, pp. 146-164
-
-
Morton, N.M.1
Seckl, J.R.2
-
2
-
-
0028973283
-
11β-Hydroxysteroid dehydrogenase is an exclusive 11β-reductase in primary cultures of rat hepatocytes: effect of physicochemical and hormonal manipulations
-
Jamieson P.M., Chapman K.E., Edwards C.R., et al. 11β-Hydroxysteroid dehydrogenase is an exclusive 11β-reductase in primary cultures of rat hepatocytes: effect of physicochemical and hormonal manipulations. Endocrinology 136 (1995) 4754-4761
-
(1995)
Endocrinology
, vol.136
, pp. 4754-4761
-
-
Jamieson, P.M.1
Chapman, K.E.2
Edwards, C.R.3
-
3
-
-
2342510149
-
Metabolic syndrome without obesity: hepatic overexpression of 11β-hydroxysteroid dehydrogenase type 1 in transgenic mice
-
Paterson J.M., Morton N.M., Fievet C., et al. Metabolic syndrome without obesity: hepatic overexpression of 11β-hydroxysteroid dehydrogenase type 1 in transgenic mice. Proc Natl Acad Sci U S A 101 (2004) 7088-7093
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 7088-7093
-
-
Paterson, J.M.1
Morton, N.M.2
Fievet, C.3
-
4
-
-
0035798621
-
Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11β-hydroxysteroid dehydrogenase type 1 null mice
-
Morton N.M., Holmes M.C., Fievet C., et al. Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11β-hydroxysteroid dehydrogenase type 1 null mice. J Biol Chem 276 (2001) 41293-41300
-
(2001)
J Biol Chem
, vol.276
, pp. 41293-41300
-
-
Morton, N.M.1
Holmes, M.C.2
Fievet, C.3
-
5
-
-
35148876079
-
11β-Hydroxysteroid dehydrogenase type 1 inhibition improves triglyceridemia through reduced liver secretion and partitions lipids towards oxidative tissues
-
Berthiaume M., Laplante M., Festuccia W.T., et al. 11β-Hydroxysteroid dehydrogenase type 1 inhibition improves triglyceridemia through reduced liver secretion and partitions lipids towards oxidative tissues. Am J Physiol Endocrinol Metab 293 (2007) E1045-E1052
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
-
-
Berthiaume, M.1
Laplante, M.2
Festuccia, W.T.3
-
6
-
-
26844460594
-
Discovery of 4-heteroarylbicyclo[2.2.2]octyltriazoles as potent and selective inhibitors of 11β-HSD1: novel therapeutic agents for the treatment of metabolic syndrome
-
Gu X., Dragovic J., Koo G.C., et al. Discovery of 4-heteroarylbicyclo[2.2.2]octyltriazoles as potent and selective inhibitors of 11β-HSD1: novel therapeutic agents for the treatment of metabolic syndrome. Bioorg Med Chem Lett 15 (2005) 5266-5269
-
(2005)
Bioorg Med Chem Lett
, vol.15
, pp. 5266-5269
-
-
Gu, X.1
Dragovic, J.2
Koo, G.C.3
-
7
-
-
0028825991
-
Intravenous lipid emulsions: removal mechanisms as compared to chylomicrons
-
Hultin M., Carneheim C., Rosenqvist K., et al. Intravenous lipid emulsions: removal mechanisms as compared to chylomicrons. J Lipid Res 36 (1995) 2174-2184
-
(1995)
J Lipid Res
, vol.36
, pp. 2174-2184
-
-
Hultin, M.1
Carneheim, C.2
Rosenqvist, K.3
-
8
-
-
67349178689
-
Additive action of 11β-HSD1 inhibition and PPAR-gamma agonism on hepatic steatosis and triglyceridemia in diet-induced obese rats
-
Berthiaume M., Laplante M., Festuccia W.T., et al. Additive action of 11β-HSD1 inhibition and PPAR-gamma agonism on hepatic steatosis and triglyceridemia in diet-induced obese rats. Int J Obes (Lond) 33 (2009) 601-604
-
(2009)
Int J Obes (Lond)
, vol.33
, pp. 601-604
-
-
Berthiaume, M.1
Laplante, M.2
Festuccia, W.T.3
-
9
-
-
12144291638
-
Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11β-hydroxysteroid dehydrogenase type 1-deficient mice
-
Morton N.M., Paterson J.M., Masuzaki H., et al. Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11β-hydroxysteroid dehydrogenase type 1-deficient mice. Diabetes 53 (2004) 931-938
-
(2004)
Diabetes
, vol.53
, pp. 931-938
-
-
Morton, N.M.1
Paterson, J.M.2
Masuzaki, H.3
-
10
-
-
23944493717
-
11β-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice
-
Hermanowski-Vosatka A., Balkovec J.M., Cheng K., et al. 11β-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice. J Exp Med 202 (2005) 517-527
-
(2005)
J Exp Med
, vol.202
, pp. 517-527
-
-
Hermanowski-Vosatka, A.1
Balkovec, J.M.2
Cheng, K.3
-
11
-
-
33646516612
-
Inhibition of 11β-hydroxysteroid dehydrogenase type 1 reduces food intake and weight gain but maintains energy expenditure in diet-induced obese mice
-
Wang S.J., Birtles S., de Schoolmeester J., et al. Inhibition of 11β-hydroxysteroid dehydrogenase type 1 reduces food intake and weight gain but maintains energy expenditure in diet-induced obese mice. Diabetologia 49 (2006) 1333-1337
-
(2006)
Diabetologia
, vol.49
, pp. 1333-1337
-
-
Wang, S.J.1
Birtles, S.2
de Schoolmeester, J.3
-
12
-
-
0030956006
-
Glucocorticoids inhibit mitochondrial matrix acyl-CoA dehydrogenases and fatty acid β-oxidation
-
Letteron P., Brahimi-Bourouina N., Robin M.A., et al. Glucocorticoids inhibit mitochondrial matrix acyl-CoA dehydrogenases and fatty acid β-oxidation. Am J Physiol 272 (1997) G1141-G1150
-
(1997)
Am J Physiol
, vol.272
-
-
Letteron, P.1
Brahimi-Bourouina, N.2
Robin, M.A.3
-
13
-
-
0028033268
-
The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression
-
Gulick T., Cresci S., Caira T., et al. The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression. Proc Natl Acad Sci U S A 91 (1994) 11012-11016
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 11012-11016
-
-
Gulick, T.1
Cresci, S.2
Caira, T.3
-
14
-
-
32644443742
-
Peroxisome proliferator-activated receptor α mediates the effects of high-fat diet on hepatic gene expression
-
Patsouris D., Reddy J.K., Muller M., et al. Peroxisome proliferator-activated receptor α mediates the effects of high-fat diet on hepatic gene expression. Endocrinology 147 (2006) 1508-1516
-
(2006)
Endocrinology
, vol.147
, pp. 1508-1516
-
-
Patsouris, D.1
Reddy, J.K.2
Muller, M.3
-
15
-
-
0034694515
-
PPARα agonists reduce 11β-hydroxysteroid dehydrogenase type 1 in the liver
-
Hermanowski-Vosatka A., Gerhold D., Mundt S.S., et al. PPARα agonists reduce 11β-hydroxysteroid dehydrogenase type 1 in the liver. Biochem Biophys Res Commun 279 (2000) 330-336
-
(2000)
Biochem Biophys Res Commun
, vol.279
, pp. 330-336
-
-
Hermanowski-Vosatka, A.1
Gerhold, D.2
Mundt, S.S.3
-
16
-
-
0030060358
-
Expression of the peroxisome proliferator-activated receptor α gene is stimulated by stress and follows a diurnal rhythm
-
Lemberger T., Saladin R., Vazquez M., et al. Expression of the peroxisome proliferator-activated receptor α gene is stimulated by stress and follows a diurnal rhythm. J Biol Chem 271 (1996) 1764-1769
-
(1996)
J Biol Chem
, vol.271
, pp. 1764-1769
-
-
Lemberger, T.1
Saladin, R.2
Vazquez, M.3
-
17
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
Yamauchi T., Kamon J., Minokoshi Y., et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 8 (2002) 1288-1295
-
(2002)
Nat Med
, vol.8
, pp. 1288-1295
-
-
Yamauchi, T.1
Kamon, J.2
Minokoshi, Y.3
-
18
-
-
33847733103
-
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions
-
Yamauchi T., Nio Y., Maki T., et al. Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions. Nat Med 13 (2007) 332-339
-
(2007)
Nat Med
, vol.13
, pp. 332-339
-
-
Yamauchi, T.1
Nio, Y.2
Maki, T.3
|