-
1
-
-
0017064976
-
The effects of morphine-and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog
-
Martin, W.R., Eades, C.G., Thompson, J.A., Huppler, R.E., and Gilbert, P.E., The effects of morphine-and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog, J. Pharmacol. Exp. Ther., 197, 517, 1976.
-
(1976)
J. Pharmacol. Exp. Ther.
, vol.197
, pp. 517
-
-
Martin, W.R.1
Eades, C.G.2
Thompson, J.A.3
Huppler, R.E.4
Gilbert, P.E.5
-
2
-
-
0014897817
-
Subjective effects of narcotic antagonists cyclazocine and nalorphine on the addiction research center inventory
-
Haerzten, C.A., Subjective effects of narcotic antagonists cyclazocine and nalorphine on the addiction research center inventory, Psychopharmacology, 18, 366, 1970.
-
(1970)
Psychopharmacology
, vol.18
, pp. 366
-
-
Haerzten, C.A.1
-
3
-
-
85057274356
-
Stereoisomers of N-allylnormetazocine: Phencyclidinelike behavioral effects in squirrel monkeys and rats
-
Brady, K. T, Balster, R.L., and May, E.L., Stereoisomers of N-allylnormetazocine: phencyclidinelike behavioral effects in squirrel monkeys and rats, Science, 8, 215, 1982.
-
(1982)
Science
, vol.8
, pp. 215
-
-
Brady, K.T.1
Balster, R.L.2
May, E.L.3
-
4
-
-
0021646668
-
Stereoisomers of [3H]-N-allylnormetazocine bind to different sites in mouse brain
-
Martin, B.R., Katzen, J.S., Woods, J.A., Tripathi, H.L., Harris, L.S., and May, E.L., Stereoisomers of [3H]-N-allylnormetazocine bind to different sites in mouse brain, J. Pharmacol. Exp. Ther., 213, 539, 1984.
-
(1984)
J. Pharmacol. Exp. Ther.
, vol.213
, pp. 539
-
-
Martin, B.R.1
Katzen, J.S.2
Woods, J.A.3
Tripathi, H.L.4
Harris, L.S.5
May, E.L.6
-
5
-
-
0019935002
-
Evidence for sigma opioid receptor: Binding of [3H]SKF 10047 to etorphine-inaccesible sites in guinea-pig brain
-
Su, T.P., Evidence for sigma opioid receptor: binding of [3H]SKF 10047 to etorphine-inaccesible sites in guinea-pig brain, J. Pharmacol. Exp. Ther., 223, 284, 1982.
-
(1982)
J. Pharmacol. Exp. Ther.
, vol.223
, pp. 284
-
-
Su, T.P.1
-
6
-
-
0021284195
-
Sigma receptors mediated the psychotomimetic efforts of N-allylnormetazocine (SKF 1007), but not its opioid agonistic properties
-
Khazan, N., Young, G.A., El-Fakany, E.E., Hong, O., and Calligaro, D., Sigma receptors mediated the psychotomimetic efforts of N-allylnormetazocine (SKF 1007), but not its opioid agonistic properties, Neuropharmacology, 23, 983, 1984.
-
(1984)
Neuropharmacology
, vol.23
, pp. 983
-
-
Khazan, N.1
Young, G.A.2
El-Fakany, E.E.3
Hong, O.4
Calligaro, D.5
-
7
-
-
0141610329
-
Naloxone-inaccessible sigma receptor in rat central nervous system
-
Tam, S.W., Naloxone-inaccessible sigma receptor in rat central nervous system, Proc. Natl. Acad. Sci. U.S.A., 80, 6703, 1983.
-
(1983)
Proc. Natl. Acad. Sci. U.S.A.
, vol.80
, pp. 6703
-
-
Tam, S.W.1
-
8
-
-
0020619765
-
Naltrexone falls to antagonize the σ effects of PCP and SKF 10047 in the dog
-
Vaupel, D.B., Naltrexone falls to antagonize the σ effects of PCP and SKF 10047 in the dog, Eur. J. Pharmacol., 92, 269, 1983.
-
(1983)
Eur. J. Pharmacol.
, vol.92
, pp. 269
-
-
Vaupel, D.B.1
-
9
-
-
0019619625
-
Phencyclidine (angel dust)/sigma “opiate” receptor: Visualization by tritium-sensitive film
-
Quirion, R., Hammer, R.P., Herkenham, M., and Pert, C.B., Phencyclidine (angel dust)/sigma “opiate” receptor: visualization by tritium-sensitive film, Proc. Natl. Acad. Sci. U.S.A., 78, 5881, 1981.
-
(1981)
Proc. Natl. Acad. Sci. U.S.A.
, vol.78
, pp. 5881
-
-
Quirion, R.1
Hammer, R.P.2
Herkenham, M.3
Pert, C.B.4
-
10
-
-
0022931475
-
Agonistic and antagonistic effects of PCP-derivatives and sigma opioids in PCP behavioral and receptor assays
-
Contreras, P.C., Quirion, R., and O’Donohue, T.L., Agonistic and antagonistic effects of PCP-derivatives and sigma opioids in PCP behavioral and receptor assays, National Institute on Drug Abuse Res. Monogr., 64, 80, 1986.
-
(1986)
National Institute on Drug Abuse Res. Monogr.
, vol.64
, pp. 80
-
-
Contreras, P.C.1
Quirion, R.2
O’Donohue, T.L.3
-
11
-
-
0022485688
-
Pharmacological and autoradiographic discrimination of sigma and phencyclidine receptor binding sites in brain with (+)-[3H]SKF 10,047, (+)-[3H]-3-[3-hydroxyphenyl]-N-(1-propyl)piperidine and [3H]-1-[1-(2-thienyl)cyclohexyl]piperidine
-
Largent, B.L., Gundlach, A.L., and Snyder, S.H., Pharmacological and autoradiographic discrimination of sigma and phencyclidine receptor binding sites in brain with (+)-[3H]SKF 10,047, (+)-[3H]-3-[3-hydroxyphenyl]-N-(1-propyl)piperidine and [3H]-1-[1-(2-thienyl)cyclohexyl]piperidine, J. Pharmacol. Exp. Ther., 238, 739, 1986.
-
(1986)
J. Pharmacol. Exp. Ther.
, vol.238
, pp. 739
-
-
Largent, B.L.1
Gundlach, A.L.2
Snyder, S.H.3
-
12
-
-
0030221291
-
Induction of c-fos gene expression by the selective sigma receptor ligand EMD 57445 in rat brain
-
Dahmen, N., Fischer, V., Hodl, P., Rujescu, D., Reuss, S., Bartoszyk, G.D., and Hiemke, C., Induction of c-fos gene expression by the selective sigma receptor ligand EMD 57445 in rat brain, Eur. Neuropsychopharmacol., 6, 237, 1996.
-
(1996)
Eur. Neuropsychopharmacol.
, vol.6
, pp. 237
-
-
Dahmen, N.1
Fischer, V.2
Hodl, P.3
Rujescu, D.4
Reuss, S.5
Bartoszyk, G.D.6
Hiemke, C.7
-
13
-
-
0026459402
-
Sigma receptors are associated with cortical limbic areas in the primate brain
-
Mash, D.C. and Zabetian, C.P., Sigma receptors are associated with cortical limbic areas in the primate brain, Synapse, 12, 195, 1992.
-
(1992)
Synapse
, vol.12
, pp. 195
-
-
Mash, D.C.1
Zabetian, C.P.2
-
14
-
-
0032054096
-
Synthesis and preliminary evaluation of [11C]NE-100 labeled in two different positions as a PET sigma receptor ligand
-
Ishiwata, K., Noguchi, J., Ishii, S., Hatano, K., Ito, K., Nabeshima, T., and Senda, M., Synthesis and preliminary evaluation of [11C]NE-100 labeled in two different positions as a PET sigma receptor ligand, Nucl. Med. Biol., 25, 195, 1998.
-
(1998)
Nucl. Med. Biol.
, vol.25
, pp. 195
-
-
Ishiwata, K.1
Noguchi, J.2
Ishii, S.3
Hatano, K.4
Ito, K.5
Nabeshima, T.6
Senda, M.7
-
15
-
-
0025009458
-
Sigma-binding sites in the brain - an emerging concept for multiple sites and their relevance for psychiatric disorders
-
Itzhak, Y. and Stein, I., Sigma-binding sites in the brain - an emerging concept for multiple sites and their relevance for psychiatric disorders, Life Sci., 47, 1073, 1990.
-
(1990)
Life Sci.
, vol.47
, pp. 1073
-
-
Itzhak, Y.1
Stein, I.2
-
16
-
-
0025881278
-
Sigma receptors. Putative links between nervous, endocrine and immune systems
-
Su, T.P., Sigma receptors. Putative links between nervous, endocrine and immune systems, Eur. J. Biochem., 200, 633, 1991.
-
(1991)
Eur. J. Biochem.
, vol.200
, pp. 633
-
-
Su, T.P.1
-
17
-
-
0001866602
-
Role of sigma binding sites in the modulation of endocrine and immune functions
-
Itzhak, Y., Ed., Academic Press, London
-
Wolfe, S.A. and De Souza, E.B., Role of sigma binding sites in the modulation of endocrine and immune functions, in Sigma Receptors, Itzhak, Y., Ed., Academic Press, London, 1994, 287.
-
(1994)
Sigma Receptors
, pp. 287
-
-
Wolfe, S.A.1
De Souza, E.B.2
-
18
-
-
0030694838
-
Neuropeptide Y and the calcitonin gene-related peptide attenuate learning impairments induced by MK-801 via a sigma receptor-related mechanism
-
Bouchard, P., Maurice, T., St. Pierre, S., Privat, A., and Quirion, R., Neuropeptide Y and the calcitonin gene-related peptide attenuate learning impairments induced by MK-801 via a sigma receptor-related mechanism, Eur. J. Neurosci., 9, 2142, 1997.
-
(1997)
Eur. J. Neurosci.
, vol.9
, pp. 2142
-
-
Bouchard, P.1
Maurice, T.2
St Pierre, S.3
Privat, A.4
Quirion, R.5
-
19
-
-
0031968154
-
Modulation of the neuronal response to N-methyl-D-aspartate by selective sigma(2) ligands
-
Couture, S. and Debonnel, G., Modulation of the neuronal response to N-methyl-D-aspartate by selective sigma(2) ligands, Synapse, 29, 62, 1998.
-
(1998)
Synapse
, vol.29
, pp. 62
-
-
Couture, S.1
Debonnel, G.2
-
20
-
-
0032487669
-
Biphasic modulatory action of the selective sigma receptor ligand SR 31742A on N-methyl-D-aspartate-induced neuronal responses in the frontal cortex
-
Liang, X. and Wang, R.Y., Biphasic modulatory action of the selective sigma receptor ligand SR 31742A on N-methyl-D-aspartate-induced neuronal responses in the frontal cortex, Brain Res., 5, 208, 1998.
-
(1998)
Brain Res.
, vol.5
, pp. 208
-
-
Liang, X.1
Wang, R.Y.2
-
21
-
-
0032102934
-
Regulation of NMDA-induced [H-3]dopamine release from rat hippocampal slices through sigma-1 binding sites
-
Chaki, S., Okuyama, S., Ogawa, S., and Tomisawa, K., Regulation of NMDA-induced [H-3]dopamine release from rat hippocampal slices through sigma-1 binding sites, Neurochem. Int., 33, 29, 1998.
-
(1998)
Neurochem. Int.
, vol.33
, pp. 29
-
-
Chaki, S.1
Okuyama, S.2
Ogawa, S.3
Tomisawa, K.4
-
22
-
-
0032482110
-
Neuropeptide Y-mediated enhancement of NMDA-stimulated [3H]dopamine release from rat prefrontal cortex is reversed by sigma1 receptor antagonists
-
Ault, D.T. and Werling, L.L., Neuropeptide Y-mediated enhancement of NMDA-stimulated [3H]dopamine release from rat prefrontal cortex is reversed by sigma1 receptor antagonists, Schizopr. Res., 31, 27, 1998.
-
(1998)
Schizopr. Res.
, vol.31
, pp. 27
-
-
Ault, D.T.1
Werling, L.L.2
-
23
-
-
0024518488
-
Sigma-receptors in endocrine organs - identification, characterization, and autoradiographic localization in rat pituitary, adrenal, testis, and ovary
-
Wolfe, S.A., Culp, S.G., and Desouza, E.B., Sigma-receptors in endocrine organs - identification, characterization, and autoradiographic localization in rat pituitary, adrenal, testis, and ovary, Endocrinology, 124, 1160, 1989.
-
(1989)
Endocrinology
, vol.124
, pp. 1160
-
-
Wolfe, S.A.1
Culp, S.G.2
Desouza, E.B.3
-
24
-
-
0032510506
-
Comparison between the effects of sigma receptor ligand JO 1784 and neuropeptide Y on immune functions
-
Song, C. and Leonard, B.E., Comparison between the effects of sigma receptor ligand JO 1784 and neuropeptide Y on immune functions, Eur. J. Pharmacol., 345, 79, 1998.
-
(1998)
Eur. J. Pharmacol.
, vol.345
, pp. 79
-
-
Song, C.1
Leonard, B.E.2
-
25
-
-
0032963297
-
Characterization of the sigma ligand panamesine, a potential antipsychotic by immune response in patients with schizophrenia and by sleep-EEG changes in normal controls
-
Frieboes, R.M., Murck, H., Antonijevic, I.A., Kraus, T., Hinze-Selch, D., Pollmächer, T., and Steiger, A., Characterization of the sigma ligand panamesine, a potential antipsychotic by immune response in patients with schizophrenia and by sleep-EEG changes in normal controls, Psychopharmacology, 141, 107, 1999.
-
(1999)
Psychopharmacology
, vol.141
, pp. 107
-
-
Frieboes, R.M.1
Murck, H.2
Antonijevic, I.A.3
Kraus, T.4
Hinze-Selch, D.5
Pollmächer, T.6
Steiger, A.7
-
26
-
-
0027340609
-
Sigma and phencyclidine receptors in the brain-endocrine-immune axis
-
Wolfe, S.A. and De Souza, E.B., Sigma and phencyclidine receptors in the brain-endocrine-immune axis, National Institute on Drug Abuse Res. Monogr., 133, 95, 1993.
-
(1993)
National Institute on Drug Abuse Res. Monogr.
, vol.133
, pp. 95
-
-
Wolfe, S.A.1
De Souza, E.B.2
-
27
-
-
0025038801
-
Different profile of electrocortical power spectrum changes after micro-infusion into the locus coeruleus of selective agonists at various opioid receptor subtypes in rats
-
Bagetta, G., De Sarro, G.B., Sakurada, S., Rispoli, V., and Nistico, G., Different profile of electrocortical power spectrum changes after micro-infusion into the locus coeruleus of selective agonists at various opioid receptor subtypes in rats, Br. J. Pharmacol., 101, 655, 1990.
-
(1990)
Br. J. Pharmacol.
, vol.101
, pp. 655
-
-
Bagetta, G.1
De Sarro, G.B.2
Sakurada, S.3
Rispoli, V.4
Nistico, G.5
-
28
-
-
0019855733
-
Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle
-
Aston-Jones, G. and Bloom, F.E., Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle, J. Neurosci., 1, 876, 1981.
-
(1981)
J. Neurosci.
, vol.1
, pp. 876
-
-
Aston-Jones, G.1
Bloom, F.E.2
-
29
-
-
0027458693
-
Interactions between U-50,488H and sigma receptor antagonists: EEG, EEG power spectral and behavioral correlates
-
Young, G.A., Hudson, G.M., Stamidis, H., and Steinfels, G.F., Interactions between U-50,488H and sigma receptor antagonists: EEG, EEG power spectral and behavioral correlates, Eur. J. Pharmacol., 231, 473, 1993.
-
(1993)
Eur. J. Pharmacol.
, vol.231
, pp. 473
-
-
Young, G.A.1
Hudson, G.M.2
Stamidis, H.3
Steinfels, G.F.4
-
30
-
-
0030754562
-
Cortical and hippocampal EEG power spectra in animal models of schizophrenia produced with methamphetamine, cocaine, and phencyclidine
-
Yamamoto, J., Cortical and hippocampal EEG power spectra in animal models of schizophrenia produced with methamphetamine, cocaine, and phencyclidine, Psychopharmacology, 131, 379, 1997.
-
(1997)
Psychopharmacology
, vol.131
, pp. 379
-
-
Yamamoto, J.1
-
31
-
-
0030293802
-
The electroencephalographic sleep pattern in schizophrenic patients treated with clozapine or classical antipsychotic drugs
-
Wetter, T.C., Lauer, C.J., Gillich, G., and Pollmächer, T., The electroencephalographic sleep pattern in schizophrenic patients treated with clozapine or classical antipsychotic drugs, J. Psychiatr. Res., 30, 411, 1996.
-
(1996)
J. Psychiatr. Res.
, vol.30
, pp. 411
-
-
Wetter, T.C.1
Lauer, C.J.2
Gillich, G.3
Pollmächer, T.4
-
32
-
-
0030790714
-
Effects of clozapine on sleep: A longitudinal study
-
Hinze-Selch, D., Mullington, J., Orth, A., Laucer, C.J., and Pollmächer, T., Effects of clozapine on sleep: a longitudinal study, Biol. Psychiatry, 42, 260, 1997.
-
(1997)
Biol. Psychiatry
, vol.42
, pp. 260
-
-
Hinze-Selch, D.1
Mullington, J.2
Orth, A.3
Laucer, C.J.4
Pollmächer, T.5
-
33
-
-
0027493098
-
Autoimmunity in schizophrenia: A review of recent findings
-
Ganguli, R., Brar, J.S., Chengappa, K.N., Yang, Z.W., Nimgaonkar, V.L., and Rabin, B.S., Autoimmunity in schizophrenia: a review of recent findings, Ann. Med., 25, 489, 1993.
-
(1993)
Ann. Med.
, vol.25
, pp. 489
-
-
Ganguli, R.1
Brar, J.S.2
Chengappa, K.N.3
Yang, Z.W.4
Nimgaonkar, V.L.5
Rabin, B.S.6
-
34
-
-
0010421159
-
Endocrine mechanisms in sleep regulation
-
Inoué, S. and Krueger, J.M., Eds., SPB Academic Publishing bv, The Hague
-
Obál, F., Jr., Opp, M., Sary, G., and Krueger, J.M., Endocrine mechanisms in sleep regulation, in Endogenous Sleep Factors, Inoué, S. and Krueger, J.M., Eds., SPB Academic Publishing bv, The Hague, 1990, 109.
-
(1990)
Endogenous Sleep Factors
, pp. 109
-
-
Obál, F.1
Opp, M.2
Sary, G.3
Krueger, J.M.4
-
35
-
-
0027311923
-
Growth hormone-releasing hormone and interleukin-1 in sleep regulation
-
Krueger, J.M. and Obál, F., Jr., Growth hormone-releasing hormone and interleukin-1 in sleep regulation, FASEB J., 7, 645, 1993.
-
(1993)
FASEB J.
, vol.7
, pp. 645
-
-
Krueger, J.M.1
Obál, F.2
-
36
-
-
0030738237
-
Open clinical trial on the sigma ligand panamesine in patients with schizophrenia
-
Frieboes, R.M., Murck, H., Wiedemann, K., Holsboer, F., and Steiger, A., Open clinical trial on the sigma ligand panamesine in patients with schizophrenia, Psychopharmacology, 132, 82, 1997.
-
(1997)
Psychopharmacology
, vol.132
, pp. 82
-
-
Frieboes, R.M.1
Murck, H.2
Wiedemann, K.3
Holsboer, F.4
Steiger, A.5
-
37
-
-
0031017222
-
Sleep in schizophrenia: A polysomnographic study on drug-naive patients
-
Lauer, C.J., Schreiber, W., Pollmächer, T., Holsboer, F., and Krieg, J.C., Sleep in schizophrenia: a polysomnographic study on drug-naive patients, Neuropsychopharmacology, 16, 51, 1997.
-
(1997)
Neuropsychopharmacology
, vol.16
, pp. 51
-
-
Lauer, C.J.1
Schreiber, W.2
Pollmächer, T.3
Holsboer, F.4
Krieg, J.C.5
-
38
-
-
0020086084
-
Stereoisomers of N-allylnormetazocine: Phencyclidinelike behavioral effects in squirrel monkeys and rats
-
Brady, K.T., Balster, R.L., and May, E.L., Stereoisomers of N-allylnormetazocine: phencyclidinelike behavioral effects in squirrel monkeys and rats, Science, 215, 178, 1982.
-
(1982)
Science
, vol.215
, pp. 178
-
-
Brady, K.T.1
Balster, R.L.2
May, E.L.3
-
39
-
-
0027984912
-
Effect of NE-100, a novel sigma receptor ligand, on phencyclidine-induced cognitive dysfunction
-
Ogawa, S., Okuyama, S., Araki, H., and Otomo, S., Effect of NE-100, a novel sigma receptor ligand, on phencyclidine-induced cognitive dysfunction, Eur. J. Pharmacol., 263, 9, 1994.
-
(1994)
Eur. J. Pharmacol.
, vol.263
, pp. 9
-
-
Ogawa, S.1
Okuyama, S.2
Araki, H.3
Otomo, S.4
-
40
-
-
0000476908
-
NE-100, a novel sigma receptor ligand: In vivo tests
-
Okuyama, S., Imagawa, Y., Ogawa, S., Araki, H., Ajima, A., Tanaka, M., Muramatsu, M., Nakazato, A., Yamaguchi, K., Yoshida, M., et al., NE-100, a novel sigma receptor ligand: in vivo tests, Life Sci., 53, PL 285-PL 290, 1993.
-
(1993)
Life Sci.
, vol.53
, pp. PL285-PL290
-
-
Okuyama, S.1
Imagawa, Y.2
Ogawa, S.3
Araki, H.4
Ajima, A.5
Tanaka, M.6
Muramatsu, M.7
Nakazato, A.8
Yamaguchi, K.9
Yoshida, M.10
-
41
-
-
0027418153
-
The sigma receptor ligand 1,3-di-(2-tolyl)guanidine in animal models of schizophrenia
-
Rückert, N.G. and Schmidt, W.J., The sigma receptor ligand 1,3-di-(2-tolyl)guanidine in animal models of schizophrenia, Eur. J. Pharmacol., 233, 261, 1993.
-
(1993)
Eur. J. Pharmacol.
, vol.233
, pp. 261
-
-
Rückert, N.G.1
Schmidt, W.J.2
-
42
-
-
0028802129
-
The sigma ligand BMY-14802 as a potential antipsychotic: Evidence from the latent inhibition model in rats
-
Weiner, I., Traub, A., Rawlins, J., Smith, A., and Feldon, J., The sigma ligand BMY-14802 as a potential antipsychotic: evidence from the latent inhibition model in rats, Behav. Pharmacol., 6, 46, 1995.
-
(1995)
Behav. Pharmacol.
, vol.6
, pp. 46
-
-
Weiner, I.1
Traub, A.2
Rawlins, J.3
Smith, A.4
Feldon, J.5
-
43
-
-
0017816468
-
Phencyclidine-induced psychosis
-
Allen, R.M. and Young, S.J., Phencyclidine-induced psychosis, Am. J. Psychiatry, 135, 1081, 1978.
-
(1978)
Am. J. Psychiatry
, vol.135
, pp. 1081
-
-
Allen, R.M.1
Young, S.J.2
-
44
-
-
45949118722
-
Classification and nomenclature of phencyclidine and sigma receptor sites
-
Quirion, R., Chicheportiche, R., Contreras, P., Johnson, K., Lodge, D., Tam, S., Woods, J., and Zukin, S., Classification and nomenclature of phencyclidine and sigma receptor sites, Trends Neurosci., 10, 444, 1987.
-
(1987)
Trends Neurosci.
, vol.10
, pp. 444
-
-
Quirion, R.1
Chicheportiche, R.2
Contreras, P.3
Johnson, K.4
Lodge, D.5
Tam, S.6
Woods, J.7
Zukin, S.8
-
45
-
-
0002766710
-
Schizophrenia and glutamate
-
Bloom, F.E. and Kupfer, D.J., Eds., Raven Press, New York
-
Bunney, B.G., Bunney, W.E., and Carlsson, A., Schizophrenia and glutamate, in Psychopharmacology: The 4th Generation of Progress, Bloom, F.E. and Kupfer, D.J., Eds., Raven Press, New York, 1995, 1205.
-
(1995)
Psychopharmacology: The 4th Generation of Progress
, pp. 1205
-
-
Bunney, B.G.1
Bunney, W.E.2
Carlsson, A.3
-
46
-
-
0029880412
-
NMDA-dependent modulation of CA1 local circuit inhibition
-
Grunze, H.C., Rainnie, D.G., Hasselmo, M.E., Barkai, E., Hearn, E.F., McCarley, R.W., and Greene, R.W., NMDA-dependent modulation of CA1 local circuit inhibition, J. Neurosci., 16, 2034, 1996.
-
(1996)
J. Neurosci.
, vol.16
, pp. 2034
-
-
Grunze, H.C.1
Rainnie, D.G.2
Hasselmo, M.E.3
Barkai, E.4
Hearn, E.F.5
McCarley, R.W.6
Greene, R.W.7
-
47
-
-
0032553577
-
Association between polymorphisms in the type 1 sigma receptor gene and schizophrenia
-
Ishiguro, H., Ohtsuki, T., Toru, M., Itokawa, M., Aoki, J., Shibuya, H., Kurumaji, A., Okubo, Y., Iwawaki, A., Ota, K., Shimizu, H., Hamaguchi, H., and Arinami, T., Association between polymorphisms in the type 1 sigma receptor gene and schizophrenia, Neurosci. Lett., 257, 45, 1998.
-
(1998)
Neurosci. Lett.
, vol.257
, pp. 45
-
-
Ishiguro, H.1
Ohtsuki, T.2
Toru, M.3
Itokawa, M.4
Aoki, J.5
Shibuya, H.6
Kurumaji, A.7
Okubo, Y.8
Iwawaki, A.9
Ota, K.10
Shimizu, H.11
Hamaguchi, H.12
Arinami, T.13
-
48
-
-
0007957168
-
Sigma opiates and certain antipsychotic drugs mutually inhibit (+)-[3H] SKF 10,047 and [3H]haloperidol binding in guinea pig brain membranes
-
Tam, S.W. and Cook, L., Sigma opiates and certain antipsychotic drugs mutually inhibit (+)-[3H] SKF 10,047 and [3H]haloperidol binding in guinea pig brain membranes, Proc. Natl. Acad. Sci. U.S.A., 81, 5618, 1984.
-
(1984)
Proc. Natl. Acad. Sci. U.S.A.
, vol.81
, pp. 5618
-
-
Tam, S.W.1
Cook, L.2
-
49
-
-
0011190242
-
1,3-Di(2-[5-3H]tolyl)guanidine: A selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs
-
Weber, E., Sonders, M., Quarum, M., McLean, S., Pou, S., and Keana, J.F., 1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs, Proc. Natl. Acad. Sci. U.S.A., 83, 8784, 1986.
-
(1986)
Proc. Natl. Acad. Sci. U.S.A.
, vol.83
, pp. 8784
-
-
Weber, E.1
Sonders, M.2
Quarum, M.3
McLean, S.4
Pou, S.5
Keana, J.F.6
-
50
-
-
0030017532
-
EMD 57445: A selective sigma receptor ligand with the profile of an atypical neuroleptic
-
Bartoszyk, G.D., Bender, H.M., Hellmann, J., Schnorr, C., and Seyfried, C.A., EMD 57445: a selective sigma receptor ligand with the profile of an atypical neuroleptic, Central Nerv. Syst. Drug Rev., 2, 175, 1996.
-
(1996)
Central Nerv. Syst. Drug Rev.
, vol.2
, pp. 175
-
-
Bartoszyk, G.D.1
Bender, H.M.2
Hellmann, J.3
Schnorr, C.4
Seyfried, C.A.5
-
51
-
-
0023471367
-
Structural determinants of sigma receptor affinity
-
Largent, B.L., Wikstrom, H., Gundlach, A.L., and Snyder, S.H., Structural determinants of sigma receptor affinity, Mol. Pharmacol., 32, 772, 1987.
-
(1987)
Mol. Pharmacol.
, vol.32
, pp. 772
-
-
Largent, B.L.1
Wikstrom, H.2
Gundlach, A.L.3
Snyder, S.H.4
-
52
-
-
0027272875
-
Current hypotheses on sigma receptors and their physiological role: Possible implications in psychiatry
-
Debonnel, G., Current hypotheses on sigma receptors and their physiological role: possible implications in psychiatry, J. Psychiatry Neurosci., 18, 157, 1993.
-
(1993)
J. Psychiatry Neurosci.
, vol.18
, pp. 157
-
-
Debonnel, G.1
-
53
-
-
2642705876
-
Effect of EMD 57445, the selective sigma receptor ligand, on the turnover and release of dopamine
-
Skuza, G., Golembiowska, K., and Wedzony, K., Effect of EMD 57445, the selective sigma receptor ligand, on the turnover and release of dopamine, Pol. J. Pharmacol., 50, 61, 1998.
-
(1998)
Pol. J. Pharmacol.
, vol.50
, pp. 61
-
-
Skuza, G.1
Golembiowska, K.2
Wedzony, K.3
-
54
-
-
0030608952
-
Release of [3H]dopamine from guinea pig striatal slices is modulated by sigma1 receptor agonists
-
Gonzalez, G.M. and Werling, L.L., Release of [3H]dopamine from guinea pig striatal slices is modulated by sigma1 receptor agonists, Naunyn Schmiedebergs Arch. Pharmacol., 356, 455, 1997.
-
(1997)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.356
, pp. 455
-
-
Gonzalez, G.M.1
Werling, L.L.2
-
55
-
-
0032055209
-
The cerebral cortex: A case for a common site of action of antipsychotics
-
Lidow, M.S., Williams, G.V., and Goldman-Rakic, P.S., The cerebral cortex: a case for a common site of action of antipsychotics, Trends Pharm. Sci., 19, 136, 1998.
-
(1998)
Trends Pharm. Sci.
, vol.19
, pp. 136
-
-
Lidow, M.S.1
Williams, G.V.2
Goldman-Rakic, P.S.3
-
56
-
-
0026031867
-
Selective loss of cerebral cortical sigma, but not PCP binding sites in schizophrenia
-
Weissman, A.D., Casanova, M.F., Kleinman, J.E., London, E.D., and De Souza, E.B., Selective loss of cerebral cortical sigma, but not PCP binding sites in schizophrenia, Biol. Psychiatry, 29, 41, 1991.
-
(1991)
Biol. Psychiatry
, vol.29
, pp. 41
-
-
Weissman, A.D.1
Casanova, M.F.2
Kleinman, J.E.3
London, E.D.4
De Souza, E.B.5
-
57
-
-
0024547561
-
Differential regulation of sigma and PCP receptors after chronic administration of haloperidol and phencyclidine in mice
-
Itzhak, Y. and Alerhand, S., Differential regulation of sigma and PCP receptors after chronic administration of haloperidol and phencyclidine in mice, FASEB J., 3, 1868, 1989.
-
(1989)
FASEB J.
, vol.3
, pp. 1868
-
-
Itzhak, Y.1
Alerhand, S.2
-
58
-
-
0025924981
-
[3H]ditolylguanidine binding to human brain sigma sites is diminished after haloperidol treatment
-
Reynolds, G.P., Brown, J.E., and Middlemiss, D.N., [3H]ditolylguanidine binding to human brain sigma sites is diminished after haloperidol treatment, Eur. J. Pharmacol., 194, 235, 1991.
-
(1991)
Eur. J. Pharmacol.
, vol.194
, pp. 235
-
-
Reynolds, G.P.1
Brown, J.E.2
Middlemiss, D.N.3
-
59
-
-
0030758498
-
Differential labeling of dopamine and sigma sites by [H-3]nemonapride and [H-3]raclopride in postmortem human brains
-
Tang, S.W., Helmeste, D.M., Fang, H., Li, M., Vu, R., Bunney, W., Potkin, S., and Jones, E.G., Differential labeling of dopamine and sigma sites by [H-3]nemonapride and [H-3]raclopride in postmortem human brains, Brain Res., 765, 7, 1997.
-
(1997)
Brain Res.
, vol.765
, pp. 7
-
-
Tang, S.W.1
Helmeste, D.M.2
Fang, H.3
Li, M.4
Vu, R.5
Bunney, W.6
Potkin, S.7
Jones, E.G.8
-
60
-
-
0022455440
-
Evidence that evidence that the potential antipsychotic agent rimcazole (BW U-234) is a specific, competitive antagonist of sigma-sites in brain
-
Ferris, R.M., Tang, F.L.M., Chang, K.J., and Russel, A., Evidence that evidence that the potential antipsychotic agent rimcazole (BW U-234) is a specific, competitive antagonist of sigma-sites in brain, Life Sci., 38, 2329, 1986.
-
(1986)
Life Sci.
, vol.38
, pp. 2329
-
-
Ferris, R.M.1
Tang, F.L.M.2
Chang, K.J.3
Russel, A.4
-
61
-
-
0020428691
-
The first clinical study of BW-234U in schizophrenia
-
Davidson, J., Miller, R., Wingfield, M., Zung, W., and Dren, A.T., The first clinical study of BW-234U in schizophrenia, Psychopharmacol. Bull., 18, 173, 1982.
-
(1982)
Psychopharmacol. Bull.
, vol.18
, pp. 173
-
-
Davidson, J.1
Miller, R.2
Wingfield, M.3
Zung, W.4
Dren, A.T.5
-
62
-
-
0021224644
-
An early phase-II clinical trial of BW234U in the treatment of acute schizophrenia in newly admitted patients
-
Chouinard, G. and Annable, L., An early phase-II clinical trial of BW234U in the treatment of acute schizophrenia in newly admitted patients, Psychopharmacology, 84, 282, 1984.
-
(1984)
Psychopharmacology
, vol.84
, pp. 282
-
-
Chouinard, G.1
Annable, L.2
-
63
-
-
0024324034
-
Rimcazole (BW234U) in the maintenance treatment of outpatients with schizophrenia
-
Munetz, M.R., Schulz, S.C., Bellin, M., and Harty, I., Rimcazole (BW234U) in the maintenance treatment of outpatients with schizophrenia, Drug Dev. Res., 16, 79, 1989.
-
(1989)
Drug Dev. Res.
, vol.16
, pp. 79
-
-
Munetz, M.R.1
Schulz, S.C.2
Bellin, M.3
Harty, I.4
-
64
-
-
0040470880
-
Clinical efficacy of sigma antagonists in schizophrenia
-
Meltzer, H.Y., Ed., Raven Press, New York
-
Borison, R.L., Pathiraja, A.P., and Diamond, B.I., Clinical efficacy of sigma antagonists in schizophrenia, in Novel Antipsychotic Drugs, Meltzer, H.Y., Ed., Raven Press, New York, 1992, 203.
-
(1992)
Novel Antipsychotic Drugs
, pp. 203
-
-
Borison, R.L.1
Pathiraja, A.P.2
Diamond, B.I.3
-
65
-
-
0028211481
-
BMY 14802, a sigma receptor ligand for the treatment of schizophrenia
-
Gewirtz, G.R., Gorman, J.M., Volavka, J., Macaluso, J., Gribkoff, G., Taylor, D.P., and Borison, R., BMY 14802, a sigma receptor ligand for the treatment of schizophrenia, Neuropsychopharmacology, 10, 37, 1994.
-
(1994)
Neuropsychopharmacology
, vol.10
, pp. 37
-
-
Gewirtz, G.R.1
Gorman, J.M.2
Volavka, J.3
Macaluso, J.4
Gribkoff, G.5
Taylor, D.P.6
Borison, R.7
-
66
-
-
0026987960
-
DuP 734 [1-(cyclopropylmethyl)-4-(2'(4''-fluorophenyl)-2'-oxoethyl)piperidine HBr], a sigma and 5-hydroxytryptamine 2 receptor antagonist: Receptor-binding, electrophysiological and neuropharmacological profiles
-
Tam, S.W., Steinfels, G.F., Gilligan, P.J., Schmidt, W.K., and Cook, L., DuP 734 [1-(cyclopropylmethyl)-4-(2'(4''-fluorophenyl)-2'-oxoethyl)piperidine HBr], a sigma and 5-hydroxytryptamine 2 receptor antagonist: receptor-binding, electrophysiological and neuropharmacological profiles, J. Pharmacol. Exp. Ther., 263, 1167, 1992.
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.263
, pp. 1167
-
-
Tam, S.W.1
Steinfels, G.F.2
Gilligan, P.J.3
Schmidt, W.K.4
Cook, L.5
-
67
-
-
84914603374
-
The sigma receptor antagonist antipsychotic DuP 734 preferentially increased dopamine turnover in the frontal cortex in rat brains
-
Rominger, C. and Tam, S.W., The sigma receptor antagonist antipsychotic DuP 734 preferentially increased dopamine turnover in the frontal cortex in rat brains, Soc. Neurosci. Abstr., 17, 333, 1991.
-
(1991)
Soc. Neurosci. Abstr.
, vol.17
, pp. 333
-
-
Rominger, C.1
Tam, S.W.2
-
68
-
-
0027006077
-
DuP 734 [1-(cyclopropylmethyl)-4-(2'(4“fluorophenyl)-2'-oxoethyl)piperidine HBr], a potential antipsychotic agent: Preclinical behavioral effects
-
Cook, L., Tam, S.W., and Rohrbach, K.W., DuP 734 [1-(cyclopropylmethyl)-4-(2'(4“fluorophenyl)-2'-oxoethyl)piperidine HBr], a potential antipsychotic agent: preclinical behavioral effects, J. Pharmacol. Exp. Ther., 263, 1159, 1992.
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.263
, pp. 1159
-
-
Cook, L.1
Tam, S.W.2
Rohrbach, K.W.3
-
69
-
-
85038174620
-
Treatment of schizophrenia with the sigma ligand EMD 57445: High degree of striatial D2-like dopamine receptor occupancy without extrapyramidal side effects
-
Gründer, G., Müller, M., Schlegel, S., Andreas, J., Wetzel, H., Schlösser, R., Eissner, D., and Benkert, O., Treatment of schizophrenia with the sigma ligand EMD 57445: high degree of striatial D2-like dopamine receptor occupancy without extrapyramidal side effects, Pharmacopsychiatry, 30, 172, 1997.
-
(1997)
Pharmacopsychiatry
, vol.30
, pp. 172
-
-
Gründer, G.1
Müller, M.2
Schlegel, S.3
Andreas, J.4
Wetzel, H.5
Schlösser, R.6
Eissner, D.7
Benkert, O.8
-
70
-
-
0025033133
-
Testing the efficacy of new neuroleptic drugs
-
Benkert, O., Maier, W., and Rickels, K., Eds., Springer, Berlin
-
Hirsch, S.R. and Barnes, T.R.E., Testing the efficacy of new neuroleptic drugs, in Methodology of the Evaluation of Psychotropic Drugs, Benkert, O., Maier, W., and Rickels, K., Eds., Springer, Berlin, 1990, 26.
-
(1990)
Methodology of the Evaluation of Psychotropic Drugs
, pp. 26
-
-
Hirsch, S.R.1
Barnes, T.R.E.2
-
71
-
-
0032922010
-
Efficacy and safety of the sigma receptor ligand EMD 57445 (Panamesine) in patients with schizophrenia: An open clinical trial
-
Huber, M.T., Gotthardt, U., Schreiber, W., and Krieg, J.C., Efficacy and safety of the sigma receptor ligand EMD 57445 (Panamesine) in patients with schizophrenia: an open clinical trial, Pharmacopsychiatry, 32, 68, 1999.
-
(1999)
Pharmacopsychiatry
, vol.32
, pp. 68
-
-
Huber, M.T.1
Gotthardt, U.2
Schreiber, W.3
Krieg, J.C.4
-
72
-
-
0030985614
-
Characterization of haloperidol and trifluperidol as subtypeselective N-methyl-D-aspartate (NMDA) receptor antagonists using [H-3]TCP and [H-3]ifenprodil binding in rat brain membranes
-
Coughenour, L.L. and Cordon, J.J., Characterization of haloperidol and trifluperidol as subtypeselective N-methyl-D-aspartate (NMDA) receptor antagonists using [H-3]TCP and [H-3]ifenprodil binding in rat brain membranes, J. Pharmacol. Exp. Ther., 280, 584, 1997.
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.280
, pp. 584
-
-
Coughenour, L.L.1
Cordon, J.J.2
-
73
-
-
0029918017
-
Efficacy and safety of an opiate sigma-receptor antagonist (SL 82.0715) in schizophrenic patients with negative symptoms: An open dose-range study
-
Modell, S., Naber, D., and Holzbach, R., Efficacy and safety of an opiate sigma-receptor antagonist (SL 82.0715) in schizophrenic patients with negative symptoms: an open dose-range study, Pharmacopsychiatry, 29, 63, 1996.
-
(1996)
Pharmacopsychiatry
, vol.29
, pp. 63
-
-
Modell, S.1
Naber, D.2
Holzbach, R.3
-
74
-
-
0032545520
-
The effects of E-5842, a sigma receptor ligand and potential atypical antipsychotic, on Fos expression in rat forebrain
-
Guitart, X. and Farre, A.J., The effects of E-5842, a sigma receptor ligand and potential atypical antipsychotic, on Fos expression in rat forebrain, Eur. J. Pharmacol., 363, 127, 1998.
-
(1998)
Eur. J. Pharmacol.
, vol.363
, pp. 127
-
-
Guitart, X.1
Farre, A.J.2
-
75
-
-
0029846298
-
Effects of clozapine on plasma cytokine and soluble cytokine receptor levels
-
Pollmächer, T., Hinze-Selch, D., and Mullington, J., Effects of clozapine on plasma cytokine and soluble cytokine receptor levels, J. Clin. Psychopharmacol., 16, 403, 1996.
-
(1996)
J. Clin. Psychopharmacol.
, vol.16
, pp. 403
-
-
Pollmächer, T.1
Hinze-Selch, D.2
Mullington, J.3
-
76
-
-
1842328036
-
Plasma levels of cytokines and soluble cytokine receptors during treatment with haloperidol
-
Pollmächer, T., Hinze-Selch, D., Fenzel, T., Kraus, T., Schuld, A., and Mullington, J., Plasma levels of cytokines and soluble cytokine receptors during treatment with haloperidol, Am. J. Psychiatry, 154, 1763, 1997.
-
(1997)
Am. J. Psychiatry
, vol.154
, pp. 1763
-
-
Pollmächer, T.1
Hinze-Selch, D.2
Fenzel, T.3
Kraus, T.4
Schuld, A.5
Mullington, J.6
-
77
-
-
0026505429
-
Neuroendocrinological and neurochemical effects of sigma ligands
-
Gudelsky, G.A. and Nash, J.F., Neuroendocrinological and neurochemical effects of sigma ligands, Neuropharmacology, 31, 157, 1992.
-
(1992)
Neuropharmacology
, vol.31
, pp. 157
-
-
Gudelsky, G.A.1
Nash, J.F.2
-
78
-
-
0029927536
-
Mechanisms of action of atypical antipsychotic drugs: A critical analysis
-
Kinon, B.J. and Lieberman, J.A., Mechanisms of action of atypical antipsychotic drugs: a critical analysis, Psychopharmacology, 124, 2, 1996.
-
(1996)
Psychopharmacology
, vol.124
, pp. 2
-
-
Kinon, B.J.1
Lieberman, J.A.2
-
79
-
-
0027313217
-
Prevention by eliprodil (SL-82.0715) of traumatic brain damage in the rat - existence of a large (18-h) therapeutic window
-
Toulmond, S., Serrano, A., Benavides, J., and Scatton, B., Prevention by eliprodil (SL-82.0715) of traumatic brain damage in the rat - existence of a large (18-h) therapeutic window, Brain Res., 620, 32, 1993.
-
(1993)
Brain Res.
, vol.620
, pp. 32
-
-
Toulmond, S.1
Serrano, A.2
Benavides, J.3
Scatton, B.4
-
80
-
-
0031283066
-
The selective sigma2-ligand Lu 28-179 has potent anxiolytic-like effects in rodents
-
Sanchez, C., Arnt, J., Costall, B., Kelly, M.E., Meier, E., Naylor, R.J., and Perregaard, J., The selective sigma2-ligand Lu 28-179 has potent anxiolytic-like effects in rodents, J. Pharmacol. Exp. Ther., 283, 1323, 1997.
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.283
, pp. 1323
-
-
Sanchez, C.1
Arnt, J.2
Costall, B.3
Kelly, M.E.4
Meier, E.5
Naylor, R.J.6
Perregaard, J.7
-
81
-
-
0029867876
-
(+)-SKF-10,047 and dextromethorphan ameliorate conditioned fear stress through the activation of phenytoin-regulated sigma 1 sites
-
Kamei, H., Kameyama, T., and Nabeshima, T., (+)-SKF-10,047 and dextromethorphan ameliorate conditioned fear stress through the activation of phenytoin-regulated sigma 1 sites, Eur. J. Pharmacol., 299, 21, 1996.
-
(1996)
Eur. J. Pharmacol.
, vol.299
, pp. 21
-
-
Kamei, H.1
Kameyama, T.2
Nabeshima, T.3
|