-
1
-
-
0030017532
-
EMD 57445: A selective sigma receptor ligand with the profile of an atypical neuroleptic
-
Bartoszyk, G.D., Bender, H., Hellmann, J., Schnorr, C. and Seyfried, C.A. (1996) EMD 57445: a selective sigma receptor ligand with the profile of an atypical neuroleptic, CNS Drug Rev. 2, 175-196.
-
(1996)
CNS Drug Rev.
, vol.2
, pp. 175-196
-
-
Bartoszyk, G.D.1
Bender, H.2
Hellmann, J.3
Schnorr, C.4
Seyfried, C.A.5
-
2
-
-
0001417950
-
Pharmacological profile of the atypical neuroleptic drug EMD 57445
-
#230.8
-
Bartoszyk, G.D., Greiner, H.E., Harting, J., Stohrer, M. and Seyfried, C.A. (1992) Pharmacological profile of the atypical neuroleptic drug EMD 57445. Soc. Neurosci. Abstr. 18, 548 (#230.8).
-
(1992)
Soc. Neurosci. Abstr.
, vol.18
, pp. 548
-
-
Bartoszyk, G.D.1
Greiner, H.E.2
Harting, J.3
Stohrer, M.4
Seyfried, C.A.5
-
3
-
-
0025826148
-
Does sigma receptor antagonism predict clinical antipsychotic efficacy?
-
Borison, R.L., Diamond, B.T. and Dren, A.T. (1991) Does sigma receptor antagonism predict clinical antipsychotic efficacy? Psychopharmacol. Bull. 27(2), 103-106.
-
(1991)
Psychopharmacol. Bull.
, vol.27
, Issue.2
, pp. 103-106
-
-
Borison, R.L.1
Diamond, B.T.2
Dren, A.T.3
-
4
-
-
0025274410
-
Metabolites of haloperidol display preferential activity at sigma receptors compared to dopamine D-2 receptors
-
Bowen, W.D., Moses, E.L., Tolentino, P.J. and Walker, J.M. (1990) Metabolites of haloperidol display preferential activity at sigma receptors compared to dopamine D-2 receptors. Eur. J. Pharmacol. 177, 111-118.
-
(1990)
Eur. J. Pharmacol.
, vol.177
, pp. 111-118
-
-
Bowen, W.D.1
Moses, E.L.2
Tolentino, P.J.3
Walker, J.M.4
-
5
-
-
0011794918
-
σ-1 and σ-2 binding sites of rat kidney
-
Bowen, W.D., Feinstein, G. and Wolfe, S.A. (1992) σ-1 and σ-2 binding sites of rat kidney. Soc. Neurosci. Abstr. 18, 456.
-
(1992)
Soc. Neurosci. Abstr.
, vol.18
, pp. 456
-
-
Bowen, W.D.1
Feinstein, G.2
Wolfe, S.A.3
-
8
-
-
0027272875
-
Current hypotheses on sigma receptors and their physiological role: Possible implications in psychiatry
-
Debonnel, G. (1993) Current hypotheses on sigma receptors and their physiological role: possible implications in psychiatry. J. Psychiatr. Neurosci. 18, 157-172.
-
(1993)
J. Psychiatr. Neurosci.
, vol.18
, pp. 157-172
-
-
Debonnel, G.1
-
9
-
-
0028115888
-
A new approach to the design of σ-2-selective ligands: Synthesis and evaluation of N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidin)ethylamine-related polyamines at σ1 and σ2 receptor subtypes
-
De Costa, B.R., Xiao-shu, H., Dominguez, C., Cutts, J., Williams, W. and Bowen, W.D. (1994) A new approach to the design of σ-2-selective ligands: synthesis and evaluation of N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidin)ethylamine-related polyamines at σ1 and σ2 receptor subtypes. J. Med. Chem. 37, 314-321.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 314-321
-
-
De Costa, B.R.1
Xiao-Shu, H.2
Dominguez, C.3
Cutts, J.4
Williams, W.5
Bowen, W.D.6
-
10
-
-
0023908860
-
The sigma receptor: A novel site implicated in psychosis and antipsychotic drug efficacy
-
Deutch, S.I., Weizmann, A., Goldmann, M.E. and Morihisa, J.M. (1988) The sigma receptor: a novel site implicated in psychosis and antipsychotic drug efficacy. Clin. Neuropharmacol. 11, 105-119.
-
(1988)
Clin. Neuropharmacol.
, vol.11
, pp. 105-119
-
-
Deutch, S.I.1
Weizmann, A.2
Goldmann, M.E.3
Morihisa, J.M.4
-
11
-
-
0025306048
-
MK-801 induces c-fos protein in thalamic and neocortical neurons of rat brain
-
Dragunow, M. and Faull, R.L.M. (1990) MK-801 induces c-fos protein in thalamic and neocortical neurons of rat brain. Neurosci. Lett. 111, 39-45.
-
(1990)
Neurosci. Lett.
, vol.111
, pp. 39-45
-
-
Dragunow, M.1
Faull, R.L.M.2
-
12
-
-
0023245615
-
Kindling stimulation induces c-fos protein(s) in granule cells of the rat dentate gyrus
-
Dragunow, M. and Robertson, H.A. (1987) Kindling stimulation induces c-fos protein(s) in granule cells of the rat dentate gyrus. Nature 329, 441-442.
-
(1987)
Nature
, vol.329
, pp. 441-442
-
-
Dragunow, M.1
Robertson, H.A.2
-
13
-
-
0025790046
-
3H]tolyl])guanidine with σ-2 binding sites in rat heart membrane preparations
-
3H]tolyl])guanidine with σ-2 binding sites in rat heart membrane preparations. Eur. J. Pharmacol. 209, 245-248.
-
(1991)
Eur. J. Pharmacol.
, vol.209
, pp. 245-248
-
-
Dumont, M.1
Lemaire, S.2
-
14
-
-
0028214032
-
Stimulant-induced psychosis, the dopamine theory of schizophrenia, and the habenula
-
Ellison, G. (1994) Stimulant-induced psychosis, the dopamine theory of schizophrenia, and the habenula. Brain Res. Rev. 19, 223-239.
-
(1994)
Brain Res. Rev.
, vol.19
, pp. 223-239
-
-
Ellison, G.1
-
15
-
-
0028170769
-
Effects of typical and atypical neuroleptics on Fos protein expression in the rat forbain
-
Fink-Jensen, A. and Kristensen, P. (1994) Effects of typical and atypical neuroleptics on Fos protein expression in the rat forbain. Neurosci. Lett. 182, 115-118.
-
(1994)
Neurosci. Lett.
, vol.182
, pp. 115-118
-
-
Fink-Jensen, A.1
Kristensen, P.2
-
16
-
-
0028211481
-
BMY 14802, a sigma receptor ligand for the treatment of schizophrenia
-
Gewirtz, G.R., German, J.M., Volavka, J., Macaluso, J., Gribkoff, G., Taylor, D.P. and Borison, R. (1994) BMY 14802, a sigma receptor ligand for the treatment of schizophrenia. Neuropsychopharmacology 10(1), 37-40.
-
(1994)
Neuropsychopharmacology
, vol.10
, Issue.1
, pp. 37-40
-
-
Gewirtz, G.R.1
German, J.M.2
Volavka, J.3
Macaluso, J.4
Gribkoff, G.5
Taylor, D.P.6
Borison, R.7
-
19
-
-
0023277535
-
Induction of c-fos like protein in spinal cord neurons following sensory stimulation
-
Hunt, S., Pnin, A. and Evan, G. (1987) Induction of c-fos like protein in spinal cord neurons following sensory stimulation. Nature 328, 632-634.
-
(1987)
Nature
, vol.328
, pp. 632-634
-
-
Hunt, S.1
Pnin, A.2
Evan, G.3
-
21
-
-
0028261604
-
Clozapine and haloperidol produce a differential pattern of immediate early gene expression in rat caudate-putamen, nucleus accumbens, lateral septum and islands of Calleja
-
MacGibbon, G.A., Lawlor, P.A., Bravo, R. and Dragunow, M. (1994) Clozapine and haloperidol produce a differential pattern of immediate early gene expression in rat caudate-putamen, nucleus accumbens, lateral septum and islands of Calleja. Mol. Brain Res. 23, 21-32.
-
(1994)
Mol. Brain Res.
, vol.23
, pp. 21-32
-
-
MacGibbon, G.A.1
Lawlor, P.A.2
Bravo, R.3
Dragunow, M.4
-
22
-
-
0017064976
-
The effects of morphine-and nalorphine-like drugs in the non-dependent and morphine-dependent chronic spinal dog
-
Martin, W.R., Eades, C.G., Thompson, J.A., Huppler, R.E. and Gilbert, P.E. (1976) The effects of morphine-and nalorphine-like drugs in the non-dependent and morphine-dependent chronic spinal dog. J. Pharmacol. Exp. Ther. 197, 517-532.
-
(1976)
J. Pharmacol. Exp. Ther.
, vol.197
, pp. 517-532
-
-
Martin, W.R.1
Eades, C.G.2
Thompson, J.A.3
Huppler, R.E.4
Gilbert, P.E.5
-
23
-
-
0026459402
-
Sigma receptors are associated with cortical limbic areas in the primate brain
-
Mash, D.C. and Zabetian, C.P. (1992) Sigma receptors are associated with cortical limbic areas in the primate brain. Synapse 12, 195.
-
(1992)
Synapse
, vol.12
, pp. 195
-
-
Mash, D.C.1
Zabetian, C.P.2
-
24
-
-
0011832194
-
Anatomical and subcellular distribution of 'sigma-1' and 'sigma-2' sites present in rat brain
-
McCann, D.J., Weissman, A.D. and Su, T.P. (1992) Anatomical and subcellular distribution of 'sigma-1' and 'sigma-2' sites present in rat brain. Soc. Neurosci. Abstr. 18, 22.
-
(1992)
Soc. Neurosci. Abstr.
, vol.18
, pp. 22
-
-
McCann, D.J.1
Weissman, A.D.2
Su, T.P.3
-
25
-
-
0023912240
-
Autoradiographic visualisation of haloperidol-sensitive sigma receptors in guinea-pig brain
-
McLean, S. and Weber, E. (1988) Autoradiographic visualisation of haloperidol-sensitive sigma receptors in guinea-pig brain. Neuroscience 25, 259-269.
-
(1988)
Neuroscience
, vol.25
, pp. 259-269
-
-
McLean, S.1
Weber, E.2
-
26
-
-
0026608061
-
Differential expression of c-Fos and zif268 in rat striatum after haloperidol, clozapine and amphetamine
-
Nguyen, T.V., Kosofsky, B.E., Birnbaum, R., Cohen, B.M. and Hyman, S.E. (1992) Differential expression of c-Fos and zif268 in rat striatum after haloperidol, clozapine and amphetamine. Proc. Natl. Acad. Sci. USA 89, 4270-4274.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 4270-4274
-
-
Nguyen, T.V.1
Kosofsky, B.E.2
Birnbaum, R.3
Cohen, B.M.4
Hyman, S.E.5
-
27
-
-
18544402362
-
70-kDa heat shock protein and c-fos gene expression after transient ischemia
-
Nowak Jr., T.S., Ikeda, J. and Nakajima, T. (1990) 70-kDa heat shock protein and c-fos gene expression after transient ischemia. Stroke 21 (Suppl.), 107S-111S.
-
(1990)
Stroke
, vol.21
, Issue.SUPPL.
-
-
Nowak T.S., Jr.1
Ikeda, J.2
Nakajima, T.3
-
28
-
-
0024577194
-
Proto-oncogene c-fos is transiently induced in the rat cerebral cortex after forebrain ischemia
-
Onodera, H., Kogure, K., Ono, Y., Igarashi, K., Kiota, Y. and Nagaoka, A. (1989) Proto-oncogene c-fos is transiently induced in the rat cerebral cortex after forebrain ischemia. Neurosci. Lett. 98, 101-104.
-
(1989)
Neurosci. Lett.
, vol.98
, pp. 101-104
-
-
Onodera, H.1
Kogure, K.2
Ono, Y.3
Igarashi, K.4
Kiota, Y.5
Nagaoka, A.6
-
29
-
-
0027503098
-
Increases in rat striatal extracellular dopamine and vacuous chewing produced by two sigma receptor ligands
-
Patrick, S.L., Walker, J.M., Perkel, J.M., Lockwood, M. and Patrick, R.L. (1993) Increases in rat striatal extracellular dopamine and vacuous chewing produced by two sigma receptor ligands. Eur. J. Pharmacol. 231, 243-249.
-
(1993)
Eur. J. Pharmacol.
, vol.231
, pp. 243-249
-
-
Patrick, S.L.1
Walker, J.M.2
Perkel, J.M.3
Lockwood, M.4
Patrick, R.L.5
-
30
-
-
0026565729
-
Neuroleptics increase c-fos expression in the forebrain: Contrasting effects of haloperidol and clozapine
-
Robertson, G.S. and Fibiger, H.C. (1992) Neuroleptics increase c-fos expression in the forebrain: contrasting effects of haloperidol and clozapine. Neuroscience 46, 315-328.
-
(1992)
Neuroscience
, vol.46
, pp. 315-328
-
-
Robertson, G.S.1
Fibiger, H.C.2
-
31
-
-
0028135046
-
Induction patterns of fos-like immunoreactivity in the forebrain as predictors of atypical antipsychotic activity
-
Robertson, G.S., Matsumura, H. and Fibiger, H.C. (1994) Induction patterns of fos-like immunoreactivity in the forebrain as predictors of atypical antipsychotic activity. J. Pharmacol. Exp. Ther. 271, 1058-1066.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.271
, pp. 1058-1066
-
-
Robertson, G.S.1
Matsumura, H.2
Fibiger, H.C.3
-
32
-
-
0024364925
-
Autographic localisation of sigma-opioid receptors in the gastrointestinal tract of the guinea pig
-
Roman, F.J., Pascaud, X., Chomette, G., Bueno, L. and Junien, J.L. (1989) Autographic localisation of sigma-opioid receptors in the gastrointestinal tract of the guinea pig. Gastroenterology 97, 76-82.
-
(1989)
Gastroenterology
, vol.97
, pp. 76-82
-
-
Roman, F.J.1
Pascaud, X.2
Chomette, G.3
Bueno, L.4
Junien, J.L.5
-
33
-
-
0027418153
-
The sigma receptor ligand 1,3-di(2-tolyl)guanidine in animal models of schizophrenia
-
Ruckert, N.G. and Schmidt, W.J. (1993) The sigma receptor ligand 1,3-di(2-tolyl)guanidine in animal models of schizophrenia. Eur. J. Pharmacol. 233, 261-267.
-
(1993)
Eur. J. Pharmacol.
, vol.233
, pp. 261-267
-
-
Ruckert, N.G.1
Schmidt, W.J.2
-
34
-
-
0023891990
-
Expression of c-fos protein in the brain: Metabolic mapping at the cellular level
-
Sagar, S., Sharp, F. and Curran, T. (1988) Expression of c-fos protein in the brain: metabolic mapping at the cellular level. Science 240, 1328-1331.
-
(1988)
Science
, vol.240
, pp. 1328-1331
-
-
Sagar, S.1
Sharp, F.2
Curran, T.3
-
36
-
-
0026631524
-
Sigma receptors in schizophrenic cerebral cortices
-
Shibuya, H., Mori, H. and Toru, M. (1992) Sigma receptors in schizophrenic cerebral cortices. Neurochem. Res. 17, 983-990.
-
(1992)
Neurochem. Res.
, vol.17
, pp. 983-990
-
-
Shibuya, H.1
Mori, H.2
Toru, M.3
-
37
-
-
0013578424
-
Phencyclidine and sigma receptor abnormalities in schizophrenic post mortem brain
-
Simpson, M.D.C., Royston, M.C., Slater, P. and Deakin, J.F.W. (1990) Phencyclidine and sigma receptor abnormalities in schizophrenic post mortem brain. Schizophr. Res. 17, 983-990.
-
(1990)
Schizophr. Res.
, vol.17
, pp. 983-990
-
-
Simpson, M.D.C.1
Royston, M.C.2
Slater, P.3
Deakin, J.F.W.4
-
38
-
-
0025179967
-
Molecular cloning and characterisation of a novel dopamine receptor (D3) as a target for neuroleptics
-
Sokoloff, P., Giros, B., Martres, M.-P., Bouthenet, M.-L. and Schwartz, J.-C, (1990) Molecular cloning and characterisation of a novel dopamine receptor (D3) as a target for neuroleptics. Nature 347, 146-151.
-
(1990)
Nature
, vol.347
, pp. 146-151
-
-
Sokoloff, P.1
Giros, B.2
Martres, M.-P.3
Bouthenet, M.-L.4
Schwartz, J.-C.5
-
39
-
-
0019423594
-
Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques
-
Su, S.-M., Raine, L. and Fanger, H. (1981) Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques. J. Histochem. Cytochem. 29, 577-580.
-
(1981)
J. Histochem. Cytochem.
, vol.29
, pp. 577-580
-
-
Su, S.-M.1
Raine, L.2
Fanger, H.3
-
40
-
-
0027853934
-
Delineating biochemical and functional properties of sigma receptors: Emerging concepts
-
Su, T.-P. (1993) Delineating biochemical and functional properties of sigma receptors: emerging concepts. Crit. Rev. Neurobiol. 7(3/4), 187-203.
-
(1993)
Crit. Rev. Neurobiol.
, vol.7
, Issue.3-4
, pp. 187-203
-
-
Su, T.-P.1
-
41
-
-
0007957168
-
3H]haloperidol binding in guinea pig brain membranes
-
3H]haloperidol binding in guinea pig brain membranes. Proc. Natl. Acad. Sci. USA 81, 5618-5621.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 5618-5621
-
-
Tam, S.W.1
Cook, L.2
-
42
-
-
0025651756
-
Sigma receptors: Biology and function
-
Walker, J.M., Bowen, W.D., Walker, F.O., Matsumoto, R.R., De Costa, B. and Rice, K.C. (1990) Sigma receptors: biology and function. Pharmacol. Rev. 42, 355-402.
-
(1990)
Pharmacol. Rev.
, vol.42
, pp. 355-402
-
-
Walker, J.M.1
Bowen, W.D.2
Walker, F.O.3
Matsumoto, R.R.4
De Costa, B.5
Rice, K.C.6
-
43
-
-
0023743170
-
Sigma receptors in post-mortem brain
-
Weissmann, A.D., Su, T.P., Hedreen, J.C. and London. E.D. (1988) Sigma receptors in post-mortem brain. J. Pharmacol. Exp. Ther. 247, 29-33.
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.247
, pp. 29-33
-
-
Weissmann, A.D.1
Su, T.P.2
Hedreen, J.C.3
London, E.D.4
-
44
-
-
0026031867
-
Selective loss of cerebral cortical sigma, but not pcp binding sites in schizophrenia
-
Weissmann, A.D., Casanova, M.F., Kleinmann, J.E., London, E.D. and De Souza, E.B. (1991) Selective loss of cerebral cortical sigma, but not PCP binding sites in schizophrenia. Biol. Psychiatry 29, 41-54.
-
(1991)
Biol. Psychiatry
, vol.29
, pp. 41-54
-
-
Weissmann, A.D.1
Casanova, M.F.2
Kleinmann, J.E.3
London, E.D.4
De Souza, E.B.5
-
45
-
-
0024518488
-
Sigma-receptors in endocrine organs: Identification, characterization and autoradiographic localisazion in rat pituitary, adrenal, testis and ovary
-
Wolfe, S.A., Culp, S.G. and De Souza, E.B. (1989) Sigma-receptors in endocrine organs: identification, characterization and autoradiographic localisazion in rat pituitary, adrenal, testis and ovary. Endocrinology 124, 1160-1172.
-
(1989)
Endocrinology
, vol.124
, pp. 1160-1172
-
-
Wolfe, S.A.1
Culp, S.G.2
De Souza, E.B.3
|