Synthesis of a new cytotoxic cephalostatin/ritterazine analogue from hecogenin and 22-epi-hippuristanol

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 1, 2010, Pages 58-63

  Poza, Javier Jesús ^a   Rodríguez, Jaime ^a   Jiménez, Carlos ^a  

^a UNIVERSITY OF A CORUÑA   (Spain)

Author keywords

22 epi Hippuristanol; Cephalostatin ritterazine analogue; Cytotoxic activity; Tumor cell lines

Indexed keywords

2 AMINO 22 EPI HIPPURIST 1 EN 3,11 DIONE; 2 AMINOHECOGENIN 1 EN 3 ONE; 22 EPI HIPPURISTAN 3,11 DIONE; 22 EPI HIPPURISTANOL; 2ALPHA BROMO 22 EPI HIPPURISTAN 3,11 DIONE; 2ALPHA BROMOHECOGENIN 3 ONE; 2ALPHA HYDROXYHECOGENIN 3 ONE; ANTINEOPLASTIC AGENT; HECOGENIN 3 ONE; HECOGENIN ACETATE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CARCINOMA; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; CYTOTOXINS; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; LUNG NEOPLASMS; PHENAZINES; SAPOGENINS; SPIRO COMPOUNDS; STEROIDS; STEROLS;

EID: 72049089815     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.11.018     Document Type: Article

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