-
1
-
-
0033545541
-
Rising incidence of hepatocellular carcinoma in the United States
-
Mar 11
-
El-Serag HB, Mason AC. Rising incidence of hepatocellular carcinoma in the United States. N Engl J Med 1999 Mar 11; 340 (10): 745-750
-
(1999)
N Engl J Med
, vol.340
, Issue.10
, pp. 745-750
-
-
El-Serag, H.B.1
Mason, A.C.2
-
2
-
-
18144411666
-
Updated treatment approach to hepatocellular carcinoma
-
Mar
-
Llovet JM. Updated treatment approach to hepatocellular carcinoma. J Gastroenterol 2005 Mar; 40 (3): 225-235
-
(2005)
J Gastroenterol
, vol.40
, Issue.3
, pp. 225-235
-
-
Llovet, J.M.1
-
3
-
-
0026378112
-
Hepatic resection versus transplantation for hepatocellular carcinoma
-
Sep discussion 8-9
-
Iwatsuki S, Starzl TE, Sheahan DG, et al. Hepatic resection versus transplantation for hepatocellular carcinoma. Ann Surg 1991 Sep; 214 (3): 221-28; discussion 8-9.
-
(1991)
Ann Surg
, vol.214
, Issue.3
, pp. 221-28
-
-
Iwatsuki, S.1
Starzl, T.E.2
Sheahan, D.G.3
-
4
-
-
0033498334
-
An analysis of 412 cases of hepatocellular carcinoma at a Western center
-
Jun, discussion 9-800
-
Fong Y, Sun RL, Jarnagin W, et al. An analysis of 412 cases of hepatocellular carcinoma at a Western center. Ann Surg 1999 Jun; 229 (6): 790-9; discussion 9-800.
-
(1999)
Ann Surg
, vol.229
, Issue.6
, pp. 790-9
-
-
Fong, Y.1
Sun, R.L.2
Jarnagin, W.3
-
5
-
-
0034941503
-
Improving survival results after resection of hepatocellular carcinoma: A prospective study of 377 patients over 10 years
-
Jul
-
Poon RT, Fan ST, Lo CM, et al. Improving survival results after resection of hepatocellular carcinoma: a prospective study of 377 patients over 10 years. Ann Surg 2001 Jul; 234 (1): 63-70.
-
(2001)
Ann Surg
, vol.234
, Issue.1
, pp. 63-70
-
-
Poon, R.T.1
Fan, S.T.2
Lo, C.M.3
-
6
-
-
6444219980
-
High pathological risk of recurrence after surgical resection for hepatocellular carcinoma: An indication for salvage liver transplantation
-
Oct
-
Sala M, Fuster J, Llovet JM, et al. High pathological risk of recurrence after surgical resection for hepatocellular carcinoma: an indication for salvage liver transplantation. Liver Transpl 2004 Oct; 10 (10): 1294-1300
-
(2004)
Liver Transpl
, vol.10
, Issue.10
, pp. 1294-1300
-
-
Sala, M.1
Fuster, J.2
Llovet, J.M.3
-
7
-
-
0029557319
-
Liver regeneration 2: Role of growth factors and cytokines in hepatic regeneration
-
Dec
-
Fausto N, Laird AD, Webber EM. Liver regeneration 2: role of growth factors and cytokines in hepatic regeneration. FASEB J 1995 Dec; 9 (15): 1527-1536
-
(1995)
FASEB J
, vol.9
, Issue.15
, pp. 1527-1536
-
-
Fausto, N.1
Laird, A.D.2
Webber, E.M.3
-
8
-
-
0027942871
-
Expression of heparin-binding epidermal growth factor in human hepatocellular carcinoma
-
Inui Y, Higashiyama S, Kawata S, et al. Expression of heparin-binding epidermal growth factor in human hepatocellular carcinoma. Gastroenterology 1994 Dec; 107 (6): 1799-1804 (Pubitemid 24357636)
-
(1994)
Gastroenterology
, vol.107
, Issue.6
, pp. 1799-1804
-
-
Inui, Y.1
Higashiyama, S.2
Kawata, S.3
Tamura, S.4
Miyagawa, J.-I.5
Taniguchi, N.6
Matsuzawa, Y.7
-
9
-
-
0030857813
-
Analysis of transforming growth factor (TGF)-alpha/epidermal growth factor receptor hepatocyte growth Factor/c-metTGF-beta receptor type II and p53 expression in human hepatocellular carcinomas
-
Jul
-
Kiss A, Wang NJ, Xie JP, et al. Analysis of transforming growth factor (TGF)-alpha/epidermal growth factor receptor, hepatocyte growth Factor/c-met,TGF-beta receptor type II, and p53 expression in human hepatocellular carcinomas. Clin Cancer Res 1997 Jul; 3 (7): 1059-1066
-
(1997)
Clin Cancer Res
, vol.3
, Issue.7
, pp. 1059-1066
-
-
Kiss, A.1
Wang, N.J.2
Xie, J.P.3
-
10
-
-
0022401482
-
Hypomethyla-tion of c-myc and epidermal growth factor receptor genes in human hepatocellular carcinoma and fetal liver
-
Dec
-
Kaneko Y, Shibuya M, Nakayama T, et al. Hypomethyla-tion of c-myc and epidermal growth factor receptor genes in human hepatocellular carcinoma and fetal liver. Jpn J Cancer Res 1985 Dec; 76 (12): 1136-1140
-
(1985)
Jpn J Cancer Res
, vol.76
, Issue.12
, pp. 1136-1140
-
-
Kaneko, Y.1
Shibuya, M.2
Nakayama, T.3
-
11
-
-
0028942819
-
Concomitant and isolated expression of TGF-alpha and EGF-R in human hepatoma cells supports the hypothesis of autocrine, paracrine, and endocrine growth of human hepatoma
-
Apr
-
Yamaguchi K, Carr BI, Nalesnik MA. Concomitant and isolated expression of TGF-alpha and EGF-R in human hepatoma cells supports the hypothesis of autocrine, paracrine, and endocrine growth of human hepatoma. J Surg Oncol 1995 Apr; 58 (4): 240-245
-
(1995)
J Surg Oncol
, vol.58
, Issue.4
, pp. 240-245
-
-
Yamaguchi, K.1
Carr, B.I.2
Nalesnik, M.A.3
-
12
-
-
0029117186
-
Nodules of less-differentiated tumor within or adjacent to hepatocellular carcinoma: Relative expression of transforming growth factor-alpha and its receptor in the different areas of tumor
-
Oct
-
Morimitsu Y, Hsia CC, Kojiro M, et al. Nodules of less-differentiated tumor within or adjacent to hepatocellular carcinoma: relative expression of transforming growth factor-alpha and its receptor in the different areas of tumor. Hum Pathol 1995 Oct; 26 (10): 1126-1132
-
(1995)
Hum Pathol
, vol.26
, Issue.10
, pp. 1126-1132
-
-
Morimitsu, Y.1
Hsia, C.C.2
Kojiro, M.3
-
13
-
-
19144366561
-
Clinical significance of vascular endothelial growth factor and basic fibroblast growth factor gene expression in liver tumor
-
Mar
-
Mise M, Arii S, Higashituji H, et al. Clinical significance of vascular endothelial growth factor and basic fibroblast growth factor gene expression in liver tumor. Hepatology 1996 Mar; 23 (3): 455-464
-
(1996)
Hepatology
, vol.23
, Issue.3
, pp. 455-464
-
-
Mise, M.1
Arii, S.2
Higashituji, H.3
-
14
-
-
8944243078
-
Expression of vascular permeability factor/vascular endothelial growth factor in human hepatocellular carcinoma
-
Jul 1
-
Suzuki K, Hayashi N, Miyamoto Y, et al. Expression of vascular permeability factor/vascular endothelial growth factor in human hepatocellular carcinoma. Cancer Res 1996 Jul 1; 56 (13): 3004-3009
-
(1996)
Cancer Res
, vol.56
, Issue.13
, pp. 3004-3009
-
-
Suzuki, K.1
Hayashi, N.2
Miyamoto, Y.3
-
15
-
-
0031807538
-
Expression of vas-cular endothelial growth factor in human hepatocellular carcinoma
-
Jul
-
Yamaguchi R, Yano H, Iemura A, et al. Expression of vas-cular endothelial growth factor in human hepatocellular carcinoma. Hepatology 1998 Jul; 28 (1): 68-77.
-
(1998)
Hepatology
, vol.28
, Issue.1
, pp. 68-77
-
-
Yamaguchi, R.1
Yano, H.2
Iemura, A.3
-
16
-
-
0030723789
-
Increased expression of vascular endothelial growth factor in human hepatocellular carcinoma
-
DOI 10.1016/S0168-8278(97)80323-6
-
Miura H, Miyazaki T, Kuroda M, et al. Increased expres-sion of vascular endothelial growth factor in human he-patocellular carcinoma. J Hepatol 1997 Nov; 27 (5): 854-861 (Pubitemid 27454829)
-
(1997)
Journal of Hepatology
, vol.27
, Issue.5
, pp. 854-861
-
-
Miura, H.1
Miyazaki, T.2
Kuroda, M.3
Oka, T.4
Machinami, R.5
Kodama, T.6
Shibuya, M.7
Makuuchi, M.8
Yazaki, Y.9
Ohnishi, S.10
-
17
-
-
0034011580
-
Expression of vascular endothelial growth factor in surgical specimens of hepato-cellular carcinoma
-
Mar
-
An FQ, Matsuda M, Fujii H, et al. Expression of vascular endothelial growth factor in surgical specimens of hepato-cellular carcinoma. J Cancer Res Clin Oncol 2000 Mar; 126 (3): 153-160
-
(2000)
J Cancer Res Clin Oncol
, vol.126
, Issue.3
, pp. 153-160
-
-
An, F.Q.1
Matsuda, M.2
Fujii, H.3
-
18
-
-
0031775790
-
Circulating vascular endothelial growth factor (VEGF) is a possible tumor marker for metastasis in human hepatocellular carcinoma
-
Jun
-
Jinno K, Tanimizu M, Hyodo I, et al. Circulating vascular endothelial growth factor (VEGF) is a possible tumor marker for metastasis in human hepatocellular carcinoma. J Gastroenterol 1998 Jun; 33 (3): 376-382
-
(1998)
J Gastroenterol
, vol.33
, Issue.3
, pp. 376-382
-
-
Jinno, K.1
Tanimizu, M.2
Hyodo, I.3
-
19
-
-
0031955570
-
Significance of vascular endothelial growth factor mRNA expression in invasion and metastasis of hepatocellular carcinoma
-
Mar
-
Li XM, Tang ZY, Zhou G, et al. Significance of vascular endothelial growth factor mRNA expression in invasion and metastasis of hepatocellular carcinoma. J Exp Clin Cancer Res 1998 Mar; 17 (1): 13-17
-
(1998)
J Exp Clin Cancer Res
, vol.17
, Issue.1
, pp. 13-17
-
-
Li, X.M.1
Tang, Z.Y.2
Zhou, G.3
-
20
-
-
10344254872
-
Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas
-
Dec 7
-
Colnot S, Decaens T, Niwa-Kawakita M, et al. Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas. Proc Natl Acad Sci U S A 2004 Dec 7; 101 (49): 17216-17221
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.49
, pp. 17216-17221
-
-
Colnot, S.1
Decaens, T.2
Niwa-Kawakita, M.3
-
21
-
-
36549013178
-
Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection
-
Jan
-
Schmitz KJ, Wohlschlaeger J, Lang H, et al. Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection. J Hepatol 2008 Jan; 48 (1): 83-90.
-
(2008)
J Hepatol
, vol.48
, Issue.1
, pp. 83-90
-
-
Schmitz, K.J.1
Wohlschlaeger, J.2
Lang, H.3
-
22
-
-
34547593907
-
Modulation of MAPK pathways and cell cycle by replicating hepatitis B virus: Factors contributing to hepatocarcinogenesis
-
Sep
-
Chin R, Earnest-Silveira L, Koeberlein B, et al. Modulation of MAPK pathways and cell cycle by replicating hepatitis B virus: factors contributing to hepatocarcinogenesis. J Hepatol 2007 Sep; 47 (3): 325-337
-
(2007)
J Hepatol
, vol.47
, Issue.3
, pp. 325-337
-
-
Chin, R.1
Earnest-Silveira, L.2
Koeberlein, B.3
-
23
-
-
0033547371
-
Close correlation be-tween beta-catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinomas
-
Nov 11
-
Terris B, Pineau P, Bregeaud L, et al. Close correlation be-tween beta-catenin gene alterations and nuclear accumulation of the protein in human hepatocellular carcinomas. Oncogene 1999 Nov 11; 18 (47): 6583-6588
-
(1999)
Oncogene
, vol.18
, Issue.47
, pp. 6583-6588
-
-
Terris, B.1
Pineau, P.2
Bregeaud, L.3
-
24
-
-
39849087850
-
Immunohistochemical ex-pression of components of the Akt-mTORC1 pathway is associated with hepatocellular carcinoma in patients with chronic liver disease
-
Mar
-
Cotler SJ, Hay N, Xie H, et al. Immunohistochemical ex-pression of components of the Akt-mTORC1 pathway is associated with hepatocellular carcinoma in patients with chronic liver disease. Dig Dis Sci 2008 Mar; 53 (3): 844-849
-
(2008)
Dig Dis Sci
, vol.53
, Issue.3
, pp. 844-849
-
-
Cotler, S.J.1
Hay, N.2
Xie, H.3
-
25
-
-
0025732215
-
Mutational hotspot in the p53 gene in human hepatocellular carcinomas
-
Apr 4
-
Hsu IC, Metcalf RA, Sun T, et al. Mutational hotspot in the p53 gene in human hepatocellular carcinomas. Nature 1991 Apr 4; 350 (6317): 427-428
-
(1991)
Nature
, vol.350
, Issue.6317
, pp. 427-428
-
-
Hsu, I.C.1
Metcalf, R.A.2
Sun, T.3
-
26
-
-
0026553679
-
Infrequent point muta-tions in codons 12 and 61 of ras oncogenes in human hepa-tocellular carcinomas
-
Mar
-
Challen C, Guo K, Collier JD, et al. Infrequent point muta-tions in codons 12 and 61 of ras oncogenes in human hepa-tocellular carcinomas. J Hepatol 1992 Mar; 14 (2-3): 342-346
-
(1992)
J Hepatol
, vol.14
, Issue.2-3
, pp. 342-346
-
-
Challen, C.1
Guo, K.2
Collier, J.D.3
-
27
-
-
0028289313
-
Mutagenesis of the H-ras protooncogene and the p53 tumor suppressor gene
-
Apr 1
-
Cerutti P, Hussain P, Pourzand C, et al. Mutagenesis of the H-ras protooncogene and the p53 tumor suppressor gene. Cancer Res 1994 Apr 1; 54 (7 Suppl.): 1934-8s.
-
(1994)
Cancer Res
, vol.54
, Issue.7 SUPPL.
-
-
Cerutti, P.1
Hussain, P.2
Pourzand, C.3
-
28
-
-
0037288792
-
Codon 64 of K-ras gene mutation pattern in hepatocellular carcinomas induced by bleomycin and 1-nitropyrene in A/J mice
-
Bai F, Nakanishi Y, Takayama K, et al. Codon 64 of K-ras gene mutation pattern in hepatocellular carcinomas induced by bleomycin and 1-nitropyrene in A/J mice. Teratog Carcinog Mutagen 2003; Suppl. 1: 161-170
-
(2003)
Teratog Carcinog Mutagen
, Issue.SUPPL. 1
, pp. 161-170
-
-
Bai, F.1
Nakanishi, Y.2
Takayama, K.3
-
29
-
-
33645742425
-
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells
-
Apr
-
Lee JS, Heo J, Libbrecht L, et al. A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells. Nat Med 2006 Apr; 12 (4): 410-416
-
(2006)
Nat Med
, vol.12
, Issue.4
, pp. 410-416
-
-
Lee, J.S.1
Heo, J.2
Libbrecht, L.3
-
30
-
-
0031048958
-
Treatment of hepatocellular carcinoma: A systematic review of randomized controlled trials
-
Feb
-
Simonetti RG, Liberati A, Angiolini C, et al. Treatment of hepatocellular carcinoma: a systematic review of randomized controlled trials. Ann Oncol 1997 Feb; 8 (2): 117-136
-
(1997)
Ann Oncol
, vol.8
, Issue.2
, pp. 117-136
-
-
Simonetti, R.G.1
Liberati, A.2
Angiolini, C.3
-
31
-
-
27144557565
-
A randomized phase III study of doxorubicin versus cisplatin/interferon alpha-2b/ doxorubicin/fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma
-
Oct 19
-
Yeo W, Mok TS, Zee B, et al. A randomized phase III study of doxorubicin versus cisplatin/interferon alpha-2b/ doxorubicin/fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma. J Natl Cancer Inst 2005 Oct 19; 97 (20): 1532-1538
-
(2005)
J Natl Cancer Inst
, vol.97
, Issue.20
, pp. 1532-1538
-
-
Yeo, W.1
Mok, T.S.2
Zee, B.3
-
32
-
-
0032765871
-
Complete pathological remission is possible with systemic combination chemotherapy for inoperable hepatocellular carcinoma
-
Jul
-
Leung TW, Patt YZ, Lau WY, et al. Complete pathological remission is possible with systemic combination chemotherapy for inoperable hepatocellular carcinoma. Clin Cancer Res 1999 Jul; 5 (7): 1676-1681
-
(1999)
Clin Cancer Res
, vol.5
, Issue.7
, pp. 1676-1681
-
-
Leung, T.W.1
Patt, Y.Z.2
Lau, W.Y.3
-
33
-
-
63449111025
-
Evolution of systemic therapy of advanced hepatocellular carcinoma
-
Nov 14
-
Yau T, Chan P, Epstein R, et al. Evolution of systemic therapy of advanced hepatocellular carcinoma. World J Gastroenterol 2008 Nov 14; 14 (42): 6437-6441
-
(2008)
World J Gastroenterol
, vol.14
, Issue.42
, pp. 6437-6441
-
-
Yau, T.1
Chan, P.2
Epstein, R.3
-
34
-
-
34547662913
-
Phase III randomized con-trolled trial comparing the survival of patients with un-resectable hepatocellular carcinoma treated with nolatrexed or doxorubicin
-
Jul 20
-
Gish RG, Porta C, Lazar L, et al. Phase III randomized con-trolled trial comparing the survival of patients with un-resectable hepatocellular carcinoma treated with nolatrexed or doxorubicin. J Clin Oncol 2007 Jul 20; 25 (21): 3069-3075
-
(2007)
J Clin Oncol
, vol.25
, Issue.21
, pp. 3069-3075
-
-
Gish, R.G.1
Porta, C.2
Lazar, L.3
-
35
-
-
0344667601
-
Gemcitabine plus ox-aliplatin for patients with advanced hepatocellular carcinoma using two different schedules
-
Dec 15
-
Taieb J, Bonyhay L, Golli L, et al. Gemcitabine plus ox-aliplatin for patients with advanced hepatocellular carcinoma using two different schedules. Cancer 2003 Dec 15; 98 (12): 2664-2670
-
(2003)
Cancer
, vol.98
, Issue.12
, pp. 2664-2670
-
-
Taieb, J.1
Bonyhay, L.2
Golli, L.3
-
36
-
-
33947495362
-
Gemcitabine plus oxaliplatin (GEMOX) in patients with advanced hepato-cellular carcinoma (HCC): Results of a phase II study
-
Apr 1
-
Louafi S, Boige V, Ducreux M, et al. Gemcitabine plus oxaliplatin (GEMOX) in patients with advanced hepato-cellular carcinoma (HCC): results of a phase II study. Cancer 2007 Apr 1; 109 (7): 1384-1390
-
(2007)
Cancer
, vol.109
, Issue.7
, pp. 1384-1390
-
-
Louafi, S.1
Boige, V.2
Ducreux, M.3
-
37
-
-
0043163428
-
Prognostic significance of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin in patients with resectable hepato-cellular carcinoma after surgery
-
May
-
Chao Y, Li CP, Chau GY, et al. Prognostic significance of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin in patients with resectable hepato-cellular carcinoma after surgery. Ann Surg Oncol 2003 May; 10 (4): 355-362
-
(2003)
Ann Surg Oncol
, vol.10
, Issue.4
, pp. 355-362
-
-
Chao, Y.1
Li, C.P.2
Chau, G.Y.3
-
38
-
-
33750621103
-
Significance of circulating endothelial progenitor cells in hepatocellular carcinoma
-
Oct
-
Ho JW, Pang RW, Lau C, et al. Significance of circulating endothelial progenitor cells in hepatocellular carcinoma. Hepatology 2006 Oct; 44 (4): 836-843
-
(2006)
Hepatology
, vol.44
, Issue.4
, pp. 836-843
-
-
Ho, J.W.1
Pang, R.W.2
Lau, C.3
-
39
-
-
34249900712
-
High serum vascular endo-thelial growth factor levels predict poor prognosis after radiofrequency ablation of hepatocellular carcinoma: Importance of tumor biomarker in ablative therapies
-
Jun
-
Poon RT, Lau C, Pang R, et al. High serum vascular endo-thelial growth factor levels predict poor prognosis after radiofrequency ablation of hepatocellular carcinoma: importance of tumor biomarker in ablative therapies. Ann Surg Oncol 2007 Jun; 14 (6): 1835-1845
-
(2007)
Ann Surg Oncol
, vol.14
, Issue.6
, pp. 1835-1845
-
-
Poon, R.T.1
Lau, C.2
Pang, R.3
-
40
-
-
33645740560
-
Expression pattern of angiogenic factors and prognosis after hepatic resection in hepatocellular carcinoma: Importance of angiopoietin-2 and hypoxia-induced factor-1 alpha
-
May
-
Wada H, Nagano H, Yamamoto H, et al. Expression pattern of angiogenic factors and prognosis after hepatic resection in hepatocellular carcinoma: importance of angiopoietin-2 and hypoxia-induced factor-1 alpha. Liver Int 2006 May; 26 (4): 414-423
-
(2006)
Liver Int
, vol.26
, Issue.4
, pp. 414-423
-
-
Wada, H.1
Nagano, H.2
Yamamoto, H.3
-
41
-
-
46449091500
-
Phase II trial evaluating the clinical and biologic effects of bevacizumab in un-resectable hepatocellular carcinoma
-
Jun 20
-
Siegel AB, Cohen EI, Ocean A, et al. Phase II trial evaluating the clinical and biologic effects of bevacizumab in un-resectable hepatocellular carcinoma. J Clin Oncol 2008 Jun 20; 26 (18): 2992-2998
-
(2008)
J Clin Oncol
, vol.26
, Issue.18
, pp. 2992-2998
-
-
Siegel, A.B.1
Cohen, E.I.2
Ocean, A.3
-
42
-
-
10844248554
-
Phase II study of thalidomide in patients with unresectable hepatocellular carcinoma
-
Jan 1
-
Lin AY, Brophy N, Fisher GA, et al. Phase II study of thalidomide in patients with unresectable hepatocellular carcinoma. Cancer 2005 Jan 1; 103 (1): 119-125
-
(2005)
Cancer
, vol.103
, Issue.1
, pp. 119-125
-
-
Lin, A.Y.1
Brophy, N.2
Fisher, G.A.3
-
43
-
-
13444303839
-
Thalidomide in the treatment of patients with hepatocellular carcinoma: A phase II trial
-
Feb 15
-
Patt YZ, Hassan MM, Lozano RD, et al. Thalidomide in the treatment of patients with hepatocellular carcinoma: a phase II trial. Cancer 2005 Feb 15; 103 (4): 749-755
-
(2005)
Cancer
, vol.103
, Issue.4
, pp. 749-755
-
-
Patt, Y.Z.1
Hassan, M.M.2
Lozano, R.D.3
-
44
-
-
71849105918
-
Sunitinib mono-therapy in patients with advanced hepatocellular carcinoma (HCC): Insights from a multidisciplinary phase II study
-
abstract no. 4521 Jan 25-27; Orlando (FL)
-
Zhu AX, Sahani DV, di Tomaso E, et al. Sunitinib mono-therapy in patients with advanced hepatocellular carcinoma (HCC): insights from a multidisciplinary phase II study [abstract no. 4521]. 2008 ASCO Gastrointestinal Cancers Symposium; 2008 Jan 25-27; Orlando (FL).
-
(2008)
2008 ASCO Gastrointestinal Cancers Symposium
-
-
Zhu, A.X.1
Sahani, D.V.2
Di Tomaso, E.3
-
45
-
-
58049201181
-
Phase II study of sunitinib malate in adult pts (pts) with metastatic or surgically unresectable hepatocellular carcinoma (HCC)
-
abstract no. 267 Jan 25-27; Orlando (FL)
-
Hoda D, Catherine C, Strosberg J, et al. Phase II study of sunitinib malate in adult pts (pts) with metastatic or surgically unresectable hepatocellular carcinoma (HCC) [abstract no. 267]. 2008 ASCO Gastrointestinal Cancers Symposium; 2008 Jan 25-27; Orlando (FL).
-
(2008)
2008 ASCO Gastrointestinal Cancers Symposium
-
-
Hoda, D.1
Catherine, C.2
Strosberg, J.3
-
46
-
-
67651165187
-
Safety and efficacy of sunitinib in patients with advanced hepatocellular carcinoma: An open-label, multicentre, phase II study
-
Faivre S, Raymond E, Boucher E, et al. Safety and efficacy of sunitinib in patients with advanced hepatocellular carcinoma: an open-label, multicentre, phase II study. Lancet Oncol 2009; 10 (8): 794-800.
-
(2009)
Lancet Oncol
, vol.10
, Issue.8
, pp. 794-800
-
-
Faivre, S.1
Raymond, E.2
Boucher, E.3
-
47
-
-
80052828056
-
-
Pfizer [ClinicalTrials.gov identifier NCT00699374]. US National Institutes of Health, ClinicalTrials.gov [online]. Available from URL Accessed 2009 Oct 23
-
Pfizer. Study of sunitinib malate versus sorafenib in patients with inoperable liver cancer [ClinicalTrials.gov identifier NCT00699374]. US National Institutes of Health, ClinicalTrials.gov [online]. Available from URL: http:// www.clinicaltrials.gov [Accessed 2009 Oct 23].
-
Study of Sunitinib Malate Versus Sorafenib in Patients with Inoperable Liver Cancer
-
-
-
48
-
-
33749017926
-
Phase II study of sorafenib in patients with advanced hepatocellular carcinoma
-
Sep 10
-
Abou-Alfa GK, Schwartz L, Ricci S, et al. Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. J Clin Oncol 2006 Sep 10; 24 (26): 4293-4300
-
(2006)
J Clin Oncol
, vol.24
, Issue.26
, pp. 4293-4300
-
-
Abou-Alfa, G.K.1
Schwartz, L.2
Ricci, S.3
-
49
-
-
47949116252
-
Sorafenib in ad-vanced hepatocellular carcinoma
-
Jul 24
-
Llovet JM, Ricci S, Mazzaferro V, et al. Sorafenib in ad-vanced hepatocellular carcinoma. N Engl J Med 2008 Jul 24; 359 (4): 378-390
-
(2008)
N Engl J Med
, vol.359
, Issue.4
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
-
50
-
-
57749189578
-
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial
-
Jan
-
Cheng AL, Kang YK, Chen Z, et al. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 2009 Jan; 10 (1): 25-34.
-
(2009)
Lancet Oncol
, vol.10
, Issue.1
, pp. 25-34
-
-
Cheng, A.L.1
Kang, Y.K.2
Chen, Z.3
-
51
-
-
33646351795
-
Phase II study of gemcitabine and oxaliplatin in combination with bev-acizumab in patients with advanced hepatocellular carcinoma
-
Apr 20
-
Zhu AX, Blaszkowsky LS, Ryan DP, et al. Phase II study of gemcitabine and oxaliplatin in combination with bev-acizumab in patients with advanced hepatocellular carcinoma. J Clin Oncol 2006 Apr 20; 24 (12): 1898-1903
-
(2006)
J Clin Oncol
, vol.24
, Issue.12
, pp. 1898-1903
-
-
Zhu, A.X.1
Blaszkowsky, L.S.2
Ryan, D.P.3
-
52
-
-
34548150925
-
Phase 2 study of erlotinib in patients with unresectable hepatocellular carcinoma
-
Sep 1
-
Thomas MB, Chadha R, Glover K, et al. Phase 2 study of erlotinib in patients with unresectable hepatocellular carcinoma. Cancer 2007 Sep 1; 110 (5): 1059-1067
-
(2007)
Cancer
, vol.110
, Issue.5
, pp. 1059-1067
-
-
Thomas, M.B.1
Chadha, R.2
Glover, K.3
-
53
-
-
27244447373
-
Phase II study of erlotinib (OSI-774) in patients with advanced hepatocel-lular cancer
-
Sep 20
-
Philip PA, Mahoney MR, Allmer C, et al. Phase II study of erlotinib (OSI-774) in patients with advanced hepatocel-lular cancer. J Clin Oncol 2005 Sep 20; 23 (27): 6657-6663
-
(2005)
J Clin Oncol
, vol.23
, Issue.27
, pp. 6657-6663
-
-
Philip, P.A.1
Mahoney, M.R.2
Allmer, C.3
-
54
-
-
60849124241
-
Phase II trial of the combination of bevacizumab and erlotinib in patients who have advanced hepatocellular carcinoma
-
Feb 20
-
Thomas MB, Morris JS, Chadha R, et al. Phase II trial of the combination of bevacizumab and erlotinib in patients who have advanced hepatocellular carcinoma. J Clin Oncol 2009 Feb 20; 27 (6): 843-850
-
(2009)
J Clin Oncol
, vol.27
, Issue.6
, pp. 843-850
-
-
Thomas, M.B.1
Morris, J.S.2
Chadha, R.3
-
55
-
-
46049097410
-
Gemcitabine plus oxaliplatin (GEMOX) combined with cetuximab in patients with progressive advanced stage hepatocellular carcinoma: Results of a multicenter phase 2 study
-
Jun 15
-
Asnacios A, Fartoux L, Romano O, et al. Gemcitabine plus oxaliplatin (GEMOX) combined with cetuximab in patients with progressive advanced stage hepatocellular carcinoma: results of a multicenter phase 2 study. Cancer 2008 Jun 15; 112 (12): 2733-2739
-
(2008)
Cancer
, vol.112
, Issue.12
, pp. 2733-2739
-
-
Asnacios, A.1
Fartoux, L.2
Romano, O.3
-
56
-
-
48249092297
-
Final results from a phase II (PhII), randomized, double-blind study of sor-afenib plus doxorubicin (S+D) versus placebo plus doxor-ubicin (P+D) in patients (pts) with advanced hepatocellular carcinoma (AHCC)
-
abstract no. 128 Jan 25-27; Orlando (FL)
-
Abou-Alfa GK, Johnson P, Knox J, et al. Final results from a phase II (PhII), randomized, double-blind study of sor-afenib plus doxorubicin (S+D) versus placebo plus doxor-ubicin (P+D) in patients (pts) with advanced hepatocellular carcinoma (AHCC) [abstract no. 128]. 2008 ASCO Gastrointestinal Cancers Symposium; 2008 Jan 25-27; Orlando (FL).
-
(2008)
2008 ASCO Gastrointestinal Cancers Symposium
-
-
Abou-Alfa, G.K.1
Johnson, P.2
Knox, J.3
-
57
-
-
34547102484
-
Phase 2 study of cetuximab in patients with advanced hepatocellular carcinoma
-
Aug 1
-
Zhu AX, Stuart K, Blaszkowsky LS, et al. Phase 2 study of cetuximab in patients with advanced hepatocellular carcinoma. Cancer 2007 Aug 1; 110 (3): 581-589
-
(2007)
Cancer
, vol.110
, Issue.3
, pp. 581-589
-
-
Zhu, A.X.1
Stuart, K.2
Blaszkowsky, L.S.3
-
58
-
-
55749088393
-
Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling
-
Oct
-
Wilhelm SM, Adnane L, Newell P, et al. Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling. Mol Cancer Ther 2008 Oct; 7 (10): 3129-3140
-
(2008)
Mol Cancer Ther
, vol.7
, Issue.10
, pp. 3129-3140
-
-
Wilhelm, S.M.1
Adnane, L.2
Newell, P.3
-
59
-
-
71849118553
-
-
Food and Drug Administration [online]. Available from URL Accessed 2009 Oct 22
-
Food and Drug Administration. FDA approves sorafenib (Nexavar) for the treatment of unresectable hepatocellular carcinoma [online]. Available from URL: http://www.asco. org/ascov2/Practice+&+Guidelines/Practice+Management+ &+Reimbursement/FDA+Drug+Alerts/FDA+approves+ sorafenib+(NEXAVAR%5BR%5D) +for+the+treatment+ of+patients+with+unresectable+hepatocellular+carcinoma [Accessed 2009 Oct 22].
-
FDA Approves Sorafenib (Nexavar) for the Treatment of Unresectable Hepatocellular Carcinoma
-
-
-
60
-
-
84961209454
-
-
[ClinicalTrials.gov identifier NCT00692770]. US National Institutes of Health, ClinicalTrials.gov [online]. Available from URL Accessed 2009 Oct 23
-
Bayer. Sorafenib as adjuvant treatment in the prevention of recurrence of hepatocellular carcinoma (STORM) [ClinicalTrials.gov identifier NCT00692770]. US National Institutes of Health, ClinicalTrials.gov [online]. Available from URL: http://www.clinicaltrials.gov [Accessed 2009 Oct 23].
-
Sorafenib As Adjuvant Treatment in the Prevention of Recurrence of Hepatocellular Carcinoma (STORM)
-
-
Bayer1
-
61
-
-
59849120213
-
Prospective, randomized, double-blind, multi-center, phase III clinical study on transarterial chemoembolization (TACE) combined with sorafenib versus TACE plus placebo in patients with hepatocellular cancer before liver transplantation-HeiLivCa [ISRCTN24081794]
-
Hoffmann K, Glimm H, Radeleff B, et al. Prospective, randomized, double-blind, multi-center, phase III clinical study on transarterial chemoembolization (TACE) combined with sorafenib versus TACE plus placebo in patients with hepatocellular cancer before liver transplantation-HeiLivCa [ISRCTN24081794]. BMC Cancer 2008; 8: 349.
-
(2008)
BMC Cancer
, vol.8
, pp. 349
-
-
Hoffmann, K.1
Glimm, H.2
Radeleff, B.3
-
62
-
-
37149017305
-
A phase II study of sunitinib in patients with advanced hepatocellular carcinoma [abstract]
-
Zhu A, Sahani D, Tomaso E. A phase II study of sunitinib in patients with advanced hepatocellular carcinoma [abstract]. Proc Am Soc Clin Oncol 2007: 4637.
-
(2007)
Proc Am Soc Clin Oncol
, pp. 4637
-
-
Zhu, A.1
Sahani, D.2
Tomaso, E.3
-
63
-
-
33750929534
-
Gefitinib in advanced unresectable hepatocellular carcinoma: Results from the Eastern Cooperative Oncology Group's Study E1203
-
abstract no. 4143 Jun 2-6; Atlanta (GA)
-
O'Dwyer PJ, Giantonio BJ, Levy DE, et al. Gefitinib in advanced unresectable hepatocellular carcinoma: results from the Eastern Cooperative Oncology Group's Study E1203 [abstract no. 4143]. 2006 ASCO Annual Meeting; 2006 Jun 2-6; Atlanta (GA).
-
(2006)
2006 ASCO Annual Meeting
-
-
O'Dwyer, P.J.1
Giantonio, B.J.2
Levy, D.E.3
-
64
-
-
68149164263
-
A phase II study of lapatinib in patients with advanced biliary tree and hepatocellular cancer
-
Sep
-
Ramanathan RK, Belani CP, Singh DA, et al. A phase II study of lapatinib in patients with advanced biliary tree and hepatocellular cancer. Cancer Chemother Pharmacol 2009 Sep; 64 4: 777-83.
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, Issue.4
, pp. 777-83
-
-
Ramanathan, R.K.1
Belani, C.P.2
Singh, D.A.3
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