Challenges in prevention and management of diabetes mellitus and metabolic syndrome in India

Current Science

Volumn 97, Issue 3, 2009, Pages 356-366

  Desai, Ankush ^a   Tandon, Nikhil ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Diabetes mellitus; Epidemiology and risk factors; Metabolic syndrome; Prevention and management

Indexed keywords

EID: 71849107539     PISSN: 00113891     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (92)

1. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of t0he expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care, Suppl. 1, 2003, S5-S20.
2. Leahy, J. L., β cell dysfunction in Type 2 diabetes mellitus. In Joslin's Diabetes Medicine (ed. Kahn, R. C.), 2005, 14th edn, pp. 449-461.
3. Hawkins, M. and Rossetti, L., Insulin resistance and its role in pathogenesis of Type 2 diabetes mellitus. In Joslin's Diabetes Medicine (ed. Kahn, R. C.), 2005, 14th edn, pp. 425-448.
4. Reaven, G. M., Banting lecture Role of insulin resistance in human disease. Diabetes, 1988, 37, 1595-1607.
5. Lemieux, I. et al., Hypertriglyceridemic waist: A marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL) in men? Circulation, 2000, 102, 179-184.
6. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. JAMA, 2001, 85, 2486-2497.
7. Alberti, K. G. and Zimmet, P. Z., Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabetic Med., 1998, 7, 539-553.
8. Einhorn, D. et al., American College of Endocrinology position statement on the insulin resistance syndrome. Endocr. Pract., 2003, 9, 237-252.
9. Alberti, K. G., Zimmet, P. and Shaw, J., IDF Epidemiology Task Force Consensus Group. The metabolic syndrome - a new worldwide definition. Lancet, 2005, 366, 1059-1062.
10. Chandalia, M., Abate, N., Garg, A., Stray-Gundersen, J. and Grundy, S. M., Relationship between generalized and upper body obesity to insulin resistance in Asian Indian men. J. Clin. Endocrinol. Metab., 1999, 84, 2329-2335.
11. Mohan, V., Deepa, M., Farooq, S., Narayan, K. M., Datta, M. and Deepa, R., Anthropometric cut points for identification of cardiometabolic risk factors in an urban Asian Indian population. Metabolism, 2007, 56, 961-968.
12. Wild, S., Roglic, G., Green, A., Sicree, R. and King, H., Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care, 2004, 27, 1047-1053.
13. Ahuja, M. M. S. (ed.), Epidemiological studies on diabetes mellitus in India. Epidemiology of Diabetes in Developing Countries, Interprint, New Delhi, 1979, pp. 29-38.
14. Ahuja, M. M. S., Recent contributions to the epidemiology of diabetes mellitus in India. Int. J. Diabetes Dev. Countries, 1991, 11, 5-9.
15. Ramachandran, A., Snehalatha, C., Dharmaraj, D. and Viswanathan, M., Prevalence of glucose intolerance in Asian Indians. Urban-rural difference and significance of upper body adiposity. Diabetes Care, 1992, 10, 1348-1355.
16. Ramachandran, A., Snehalatha, C., Latha, E., Vijay, V. and Viswanathan, M., Rising prevalence of NIDDM in an urban population in India. Diabetologia, 1997, 40, 232-237.
17. Ramachandran, A. et al., Diabetes Epidemiology Study Group in India (DESI). High prevalence of diabetes and impaired glucose tolerance in India: National Urban Diabetes Survey. Diabetologia, 2001, 44, 1094-1101.
18. Asha Bai, P. V., Murthy, B. N., Chellamariappan, M., Gupte, M. D. and Krishnaswami, C. V., Prevalence of known diabetes in Chennai city. J. Assoc. Physicians India, 2001, 49, 974-981.
19. Sadikot, S. M. et al., DiabetesIndia. The burden of diabetes and impaired glucose tolerance in India using the WHO 1999 criteria: prevalence of diabetes in India study (PODIS). Diabetes Res. Clin. Pract., 2004, 66, 301-307.
20. Mohan, V., Deepa, M., Deepa, R., Shanthirani, C. S., Farooq, S., Ganesan, A. and Datta, M., Secular trends in the prevalence of diabetes and impaired glucose tolerance in urban South India - the Chennai Urban Rural Epidemiology Study (CURES-17). Diabetologia, 2006, 49, 1175-1178.
21. Reddy, K. S. et al., Methods for establishing a surveillance system for cardiovascular diseases in Indian industrial populations. Bull. WHO, 2006, 84, 461-469.
22. Menon, V. U., Kumar, K. V., Gilchrist, A., Sugathan, T. N., Sundaram, K. R., Nair, V. and Kumar, H., Prevalence of known and undetected diabetes and associated risk factors in central Kerala - ADEPS. Diabetes Res. Clin. Pract., 2006, 74, 289-294.
23. Mohan, V. et al., Urban rural differences in prevalence of selfreported diabetes in India - the WHO-ICMR Indian NCD risk factor surveillance. Diabetes Res. Clin. Pract., 2008, 80, 159-168.
24. Zargar, A. H., Khan, A. K., Masoodi, S. R., Laway, B. A., Wani, A. I., Bashir, M. I. and Dar, F. A., Prevalence of type 2 diabetes mellitus and impaired glucose tolerance in the Kashmir Valley of the Indian subcontinent. Diabetes Res. Clin. Pract., 2000, 47, 135-146.
25. Dunstan, D. W. et al., The rising prevalence of diabetes and impaired glucose tolerance: the Australian Diabetes, Obesity and Lifestyle Study. Diabetes Care, 2002, 25, 829-834.
26. Deepa, R., Shanthirani, C. S., Premalatha, G., Sastry, N. G. and Mohan, V., Prevalence of insulin resistance syndrome in a selected south Indian population - the Chennai urban population study-7 [CUPS-7]. Indian J. Med. Res., 2002, 115, 118-127.
27. Ramachandran, A., Snehalatha, C., Satyavani, K., Sivasankari, S. and Vijay, V., Metabolic syndrome in urban Asian Indian adults - a population study using modified ATP III criteria. Diabetes Res. Clin. Pract., 2003, 60, 199-204.
28. Gupta, R., Deedwania, P. C., Gupta, A., Rastogi, S., Panwar, R. B. and Kothari, K., Prevalence of metabolic syndrome in an Indian urban population. Int. J. Cardiol., 2004, 97, 257-261.
29. Prabhakaran, D., Chaturvedi, V., Shah, P., Manhapra, A., Jeemon, P., Shah, B. and Reddy, K. S., Differences in the prevalence of metabolic syndrome in urban and rural India: a problem of urbanization. Chronic Illn., 2007, 3, 8-19.
30. Deepa, M., Farooq, S., Datta, M., Deepa, R. and Mohan, V., Prevalence of metabolic syndrome using WHO, ATPIII and IDF definitions in Asian Indians: the Chennai Urban Rural Epidemiology Study (CURES-34). Diabetes Metab. Res. Rev., 2007, 23, 127-134.
31. Misra, A. et al., High prevalence of insulin resistance in postpubertal Asian Indian children is associated with adverse truncal body fat patterning, abdominal adiposity and excess body fat. Int. J. Obes. Relat. Metab. Disord., 2004, 28, 1217-1226.
32. Radha, V., Role of genetic polymorphism peroxisome proliferatoractivated receptor-gamma2 Pro12Ala on ethnic susceptibility to diabetes in South-Asian and Caucasian subjects: evidence for heterogeneity. Diabetes Care, 2004, 29, 1046-1051.
33. Vimaleswaran, K. S. et al., Peroxisome proliferator-activated receptor-gamma co-activator-1alpha (PGC-1alpha) gene polymorphisms and their relationship to Type 2 diabetes in Asian Indians. Diabetic Med., 2005, 22, 1516-1521.
34. Vimaleswaran, K. S. et al., Effect of polymorphisms in the PPARGC1A gene on body fat in Asian Indians. Int. J. Obes. (London), 2006, 30, 884-891.
35. Reddy, K. S. and Yusuf, S., Emerging epidemic of cardiovascular disease in developing countries. Circulation, 1998, 97, 596-601.
36. Mohan, V., Shanthirani, S., Deepa, R., Premalatha, G., Sastry, N. G. and Saroja, R., Chennai Urban Population Study (CUPS No. 4). Intra-urban differences in the prevalence of the metabolic syndrome in southern India - the Chennai Urban Population Study (CUPS No. 4). Diabetic Med., 2001, 18, 280-287.
37. Mohan, V., Gokulakrishnan, K., Deepa, R., Shanthirani, C. S. and Datta, M., Association of physical inactivity with components of metabolic syndrome and coronary artery disease - the Chennai Urban Population Study (CUPS No. 15). Diabetic Med., 2005, 22, 1206-1211.
38. Mohan, V., Sudha, V., Radhika, G., Radha, V., Rema, M. and Deepa, R., Gene-environment interactions and the diabetes epidemic in India. Forum Nutr., 2007, 60, 118-126.
39. Schulze, M. B., Manson, J. E., Ludwig, D. S., Colditz, G. A., Stampfer, M. J., Willett, W. C. and Hu, F. B., Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women. JAMA, 2004, 292, 927-934.
40. Lee, D. H., Lee, I. K., Song, K., Steffes, M., Toscano, W., Baker, B. A. and Jacobs Jr, D. R., A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999-2002. Diabetes Care, 2006, 29, 1638-1644.
41. Zittermann, A., Vitamin D in preventive medicine: are we ignoring the evidence? Br. J. Nutr., 2003, 89, 552-572.
42. Reddy, K. S. et al., Educational status and cardiovascular risk profile in Indians. Proc. Natl. Acad. Sci. USA, 2007, 104, 16263-16268.
43. Mohan, V., Sandeep, S., Deepa, M., Gokulakrishnan, K., Datta, M. and Deepa, R., A diabetes risk score helps identify metabolic syndrome and cardiovascular risk in Indians - the Chennai Urban Rural Epidemiology Study (CURES-38). Diabetes Obes. Metab., 2007, 9, 337-343.
44. Barker, D. J., Hales, C. N., Fall, C. H., Osmond, C., Phipps, K. and Clark, P. M., Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia, 1993, 36, 62-67.
45. Barker, D. J. P., Mothers, Babies and Health in Later Life, Churchill Livingstone, London, 1998.
46. Hattersley, A. T. and Tooke, J. E., The fetal insulin hypothesis: an alternative explanation of the association of low birth weight with diabetes and vascular disease. Lancet, 1999, 353, 1789-1792.
47. Yajnik, C. S. et al., Fetal growth and glucose and insulin metabolism in four-year-old Indian children. Diabetic Med., 1995, 12, 330-336.
48. Bavdekar, A. et al., Insulin resistance syndrome in 8-year-old Indian children: small at birth, big at 8 years, or both? Diabetes, 1999, 48, 2422-2429.
49. Bhargava, S. K. et al., Relation of serial changes in childhood body-mass index to impaired glucose tolerance in young adulthood. N. Engl. J. Med., 2004, 350, 865-875.
50. Sachdev, H. S. et al., Anthropometric indicators of body composition in young adults: relation to size at birth and serial measurements of body mass index in childhood in the New Delhi birth cohort. Am. J. Clin. Nutr., 2005, 82, 456-466.
51. Fall, C. H., Stein, C. E., Kumaran, K., Cox, V., Osmond, C., Barker, D. J. and Hales, C. N., Size at birth, maternal weight, and type 2 diabetes in South India. Diabetic. Med., 1998, 15, 220-227.
52. Yajnik, C. S., Obesity epidemic in India: intrauterine origins? Proc. Nutr. Soc., 2004, 63, 387-396.
53. Nathan, D. M., Long-term complications of diabetes mellitus. N. Engl. J. Med., 1993, 328, 1676-1685.
54. Kapur, A., Economic analysis of diabetes care. Indian J. Med. Res., 2007, 125, 473-482.
55. Rayappa, P. H., Raju, K. N. M., Kapur, A., Bjork, S., Sylvist, C. and Dilip Kumar, K. M., Economic costs of diabetes care - the Bangalore Urban District Diabetes Study. Int. J. Diabetes Dev. Countries, 1999, 19, 87-96.
56. Grover, S., Avasthi, A., Bhansali, A., Chakrabarti, S. and Kulhara, P., Cost of ambulatory care of diabetes mellitus: a study from north India. Postgrad, Med. J., 2005, 81, 391-395.
57. Kapur, A., Cost of diabetes in India - the CODI study. In Proceedings of the Novo Nordisk Diabetes Update (eds Kapur, A. and Joshi, J. K.), Healthcare Communications Ltd, Bangalore, 2000, pp. 71-77.
58. Rose, G., Sick individuals and sick populations. Int. J. Epidemiol., 1985, 14, 32-38.
59. Green, L., Daniel, M. and Novick, L., Partnerships and coalitions for community-based research. Public Health Rep. (Suppl. 1), 2001, 116, 20-31.
60. Pan, X. R. et al., Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study. Diabetes Care, 1997, 20, 537-544.
61. Tuomilehto, J. et al., Finnish Diabetes Prevention Study Group. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N. Engl. J. Med., 2001, 344, 1343-1350.
62. Knowler, W. C., Barrett-Connor, E., Fowler, S. E., Hamman, R. F., Lachin, J. M., Walker, E. A. and Nathan, D. M., Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N. Engl. J. Med., 2002, 346, 393-403.
63. Chiasson, J. L., Josse. R. G., Gomis, R., Hanefeld, M., Karasik, A. and Laakso, M., STOP-NIDDM Trail Research Group. Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet, 2002, 359, 2072-2077.
64. Torgerson, J. S., Hauptman, J., Boldrin, M. N. and Sjöström, L., XENical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Diabetes Care, 2004, 27, 155-161.
65. Buchanan, T. A. et al., Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk hispanic women. Diabetes, 2002, 51, 2796-2803.
66. DREAM Trial Investigators, Bosch, J. et al., Effect of ramipril on the incidence of diabetes. N. Engl. J. Med., 2006, 355, 1551-1562.
67. DREAM (Diabetes Education Assessment with ramipril and rosiglitazone Medication) Trial Investigators, Gerstein, H. C. et al., Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial. Lancet, 2006, 368, 1096-1105.
68. Ramachandran, A., Snehalatha, C., Mary, S., Mukesh, B., Bhaskar, A. D. and Vijay, V., Indian Diabetes Prevention Programme (IDPP). The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1). Diabetologia, 2006, 49, 289-297.
69. Ramachandran, A., Snehalatha, C., Vijay, V., Wareham, N. J. and Colagiuri, S., Derivation and validation of diabetes risk score for urban Asian Indians. Diabetes Res. Clin. Pract., 2005, 70, 63-70.
70. The Diabetes Prevention Program Research Group, The Diabetes Prevention Program (DPP): Description of lifestyle intervention. Diabetes Care, 2002, 25, 2165-2171.
71. The Diabetes Prevention Program Research Group, Within-trial cost-effectiveness of lifestyle intervention or metformin for the primary prevention of Type 2 diabetes. Diabetes Care, 2003, 26, 2518-2523.
72. Herman, W. H. et al., Diabetes Prevention Program Research Group. The cost-effectiveness of lifestyle modification or metformin in preventing type 2 diabetes in adults with impaired glucose tolerance. Ann. Intern. Med., 2005, 142, 323-332.
73. Eddy, D. M., Schlessinger, L. and Kahn, R., Clinical outcomes and cost-effectiveness of strategies for managing people at high risk for diabetes. Ann. Intern. Med., 2005, 143, 251-264.
74. Ramachandran, A., Snehalatha, C., Yamuna, A., Mary, S. and Ping, Z., Cost-effectiveness of the interventions in the primary prevention of diabetes among Asian Indians: within-trial results of the Indian Diabetes Prevention Programme (IDPP). Diabetes Care, 2007, 30, 2548-2552.
75. Satterfield, D. W. et al., Community-based lifestyle interventions to prevent type 2 diabetes. Diabetes Care, 2003, 26, 2643-2652.
76. Mohan, V., Shanthirani, C. S., Deepa, M., Datta, M., Williams, O. D. and Deepa, R., Community empowerment - a successful model for prevention of non-communicable diseases in India - the Chennai Urban Population Study (CUPS-17). J. Assoc. Physicians India, 2006, 54, 858-862.
77. Balagopal, P., Kamalamma, N., Patel, T. G. and Misra, R., A community-based diabetes prevention and management education program in a rural village in India. Diabetes Care, 2008, Mar 3, Epub ahead of print.
78. UK Prospective Diabetes Study (UKPDS) Group: intensive bloodglucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet, 1998, 352, 837-853.
79. American Diabetes Association, Standards of medical care in diabetes - 2008. Diabetes Care (Suppl. 1), 2008, 31, S12-S54.
80. Ong, K. L., Cheung, B. M., Man, Y. B., Wong, L. Y., Wat, N. M., Tan, K. C. and Lam, K. S., Treatment and control of diabetes mellitus in the United States National Health and Nutrition Examination Survey, 1999-2002. J. Cardiometab. Syndr., 2006, 1, 301-307.
81. Raheja, B. S. et al., DiabCare Asia-India Study: diabetes care in India - current status. J. Assoc. Physicians India, 2001, 49, 717-722.
82. Nagpal, J. and Bhartia, A., Quality of diabetes care in the middle - and high-income group populace: the Delhi Diabetes Community (DEDICOM) survey. Diabetes Care, 2006, 29, 2341-2348.
83. Sharma, H., Chandola, H. M., Singh, G. and Basisht, G., Utilization of Ayurveda in health care: an approach for prevention, health promotion, and treatment of disease. Part 2 - Ayurveda in primary health care. J. Altern. Complement. Med., 2007, 13, 1135-1150.
84. Elder, C., Ayurveda for diabetes mellitus: a review of the biomedical literature. Altern. Ther. Health Med., 2004, 10, 44-50.
85. Manyam, B. V., Diabetes mellitus, Ayurveda, and yoga. J. Altern. Complement. Med., 2004, 10, 223-225.
86. Takano, T., Nakamura, K. and Watanabe, M., Urban residential environments and senior citizens' longevity in megacity areas: the importance of walkable green spaces. J. Epidemiol. Community Health, 2002, 56, 913-918.
87. Booth, M. L., Owen, N., Bauman, A., Clavisi, O. and Leslie, E., Social-cognitive and perceived environment influences associated with physical activity in older Australians. Prev. Med., 2000, 31, 15-22.
88. Marwaha, R. K., Tandon, N., Singh, Y., Aggarwal, R., Grewal, K. and Mani, K., A study of growth parameters and prevalence of overweight and obesity in school children from Delhi. Indian Pediatr., 2006, 43, 943-952.
89. Sachdev, H. P., Nutritional transition in the backdrop of early life origin of adult diseases: a challenge for the future. Indian J. Med. Res., 2004, 119, iii-v.
90. Wald, N. J. and Law, M. R., A strategy to reduce cardiovascular disease by more than 80%. BMJ, 2003, 326, 1419.
91. Reddy, K. S., The preventive polypill - much promise, insufficient evidence. N. Engl. J. Med., 2007, 356, 212.
92. Kuehn, B. M., 'Polypill' could slash diabetes risks. JAMA, 2006, 296, 377-380.