Effects of low-magnitude, high-frequency mechanical stimulation in the rat osteopenia model

Osteoporosis International

Volumn 20, Issue 12, 2009, Pages 1999-2008

  Sehmisch, S ^a   Galal, R ^a   Kolios, L ^a   Tezval, M ^a   Dullin, C ^a   Zimmer, S ^a   Stuermer, K M ^a   Stuermer, E K ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Mechanical stimuli; Osteoporosis; Trabecular bone; Whole body vibration

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOMECHANICS; BONE DENSITY; BONE MASS; BONE STRENGTH; CLINICAL EVALUATION; COMPARATIVE STUDY; CONTROLLED STUDY; CORTICAL BONE; EXPERIMENTAL MODEL; FEMALE; FREQUENCY MODULATION; GROUPS BY AGE; MECHANICAL STIMULATION; MORPHOMETRICS; NONHUMAN; OSTEOPENIA; OSTEOPOROSIS; OVARIECTOMY; PRIORITY JOURNAL; RAT; SHAM PROCEDURE; SPRAGUE DAWLEY RAT; TRABECULAR BONE; WHOLE BODY VERTICAL VIBRATION; YOUNG MODULUS;

ALKALINE PHOSPHATASE; ANIMALS; BONE DENSITY; DISEASE MODELS, ANIMAL; ELASTIC MODULUS; FEMALE; OSTEOPOROSIS; PHYSICAL STIMULATION; RATS; RATS, SPRAGUE-DAWLEY; VIBRATION; WEIGHT-BEARING;

EID: 71849099138     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-009-0892-3     Document Type: Article

References (40)

1. E Siris JD Adachi Y Lu, et al. 2002 Effects of raloxifene on fracture severity in postmenopausal women with osteoporosis: results from the MORE study. Multiple Outcomes of Raloxifene Evaluation Osteoporos Int 13 907 913 10.1007/s001980200125 1:CAS:528:DC%2BD38Xot12mur8%3D 12415439 (Pubitemid 35364793)
2. R Lindsay JC Gallagher M Kleerekoper, et al. 2005 Bone response to treatment with lower doses of conjugated estrogens with and without medroxyprogesterone acetate in early postmenopausal women Osteoporos Int 16 372 379 10.1007/s00198-004-1773-4 1:CAS:528:DC%2BD2MXisVCitrg%3D 15654581 (Pubitemid 40487394)
3. HK Genant PD Delmas P Chen, et al. 2007 Severity of vertebral fracture reflects deterioration of bone microarchitecture Osteoporos Int 18 69 76 10.1007/s00198-006-0199-6 1:STN:280:DC%2BD28jgtFWlug%3D%3D 17028792 (Pubitemid 44885497)
4. Marcus R, Feldman D, Kelsey J (eds) (2007) Osteoporosis. Elsevier Science & Technology, St. Louis
5. CH Turner Y Takano I Owan 1995 Aging changes mechanical loading thresholds for bone formation in rats J Bone Miner Res 10 1544 1549 1:STN:280:DyaK287hsF2rsQ%3D%3D 8686511
6. H Oxlund NB Andersen G Ortoft, et al. 1998 Growth hormone and mild exercise in combination markedly enhance cortical bone formation and strength in old rats Endocrinology 139 1899 1904 10.1210/en.139.4.1899 1:CAS:528: DyaK1cXitVKltrY%3D 9528976
7. C Rubin AS Turner R Müller, et al. 2002 Quantity and quality of trabecular bone in the femur are enhanced by a strongly anabolic, noninvasive mechanical intervention J Bone Miner Res 17 349 357 10.1359/jbmr.2002.17.2.349 11811566
8. C Rubin AS Turner C Mallinckrodt, et al. 2002 Mechanical strain, induced noninvasively in the high-frequency domain, is anabolic to cancellous bone, but not cortical bone Bone 30 445 452 10.1016/S8756-3282(01)00689-5 1:STN:280:DC%2BD387otVegsg%3D%3D 11882457 (Pubitemid 34204118)
9. J Flieger T Karachalios L Khaldi, et al. 1998 Mechanical stimulation in the form of vibration prevents postmenopausal bone loss in ovariectomized rats Calcif Tissue Int 63 510 514 10.1007/s002239900566 1:CAS:528:DyaK1cXnsVOhtr8%3D 9817946 (Pubitemid 28531801)
10. S Judex X Lei D Han, et al. 2007 Low-magnitude mechanical signals that stimulate bone formation in the ovariectomized rat are dependent on the applied frequency but not on the strain magnitude J Biomech 40 1333 1339 10.1016/j.jbiomech.2006.05.014 16814792 (Pubitemid 46483448)
11. M Hadjiargyrou K McLeod JP Ryaby, et al. 1998 Enhancement of fracture healing by low intensity ultrasound Clin Orthop Relat Res 355 216 229 10.1097/00003086-199810001-00022
12. AE Goodship 2008 Genetically modified mechanostats: implications for skeletal competence? J Musculoskelet Neuronal Interact 8 10 11 1:STN:280:DC%2BD1c3jvVGhuw%3D%3D 18398251
13. DD Thompson HA Simmons CM Pirie, et al. 1995 FDA guidelines and animal models for osteoporosis Bone 17 125 133 10.1016/8756-3282(95)97353-H
14. TJ Wronski PL Lowry CC Walsh, et al. 1985 Skeletal alterations in ovarectomized rats Calcif Tiss Int 37 324 328 10.1007/BF02554882 1:STN:280:DyaL2M3lsVSmuw%3D%3D (Pubitemid 15034552)
15. EK Stürmer D Seidlová-Wuttke S Sehmisch, et al. 2006 Standardized bending and breaking test for the normal and osteoporotic metaphyseal tibias of the rat: effect of estradiol, testosterone, and raloxifene J Bone Miner Res 21 89 96 10.1359/JBMR.050913 16355277 (Pubitemid 43023230)
16. KM Sturmer 1980 Mikroradiographie des Knochens, Technik, Aussagekraft und Planimetrie Hefte Unfallheilk 148 247 251
17. AM Parfitt MK Drezner FH Glorieux, et al. 1987 Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee J Bone Miner Res 2 595 610 1:STN:280:DyaL1czjvVemsQ%3D%3D 3455637
18. Sehmisch S, Dullin C, Zaroban A et al. (2008) The use of flat panel volumetric computed tomography (fpVCT) in osteoporosis research. Academic Radiology in press
19. S Ikeda H Tsurukami M Ito, et al. 2001 Effect of trabecular bone contour on ultimate strength of lumbar vertebra after bilateral ovariectomy in rats Bone 28 625 633 10.1016/S8756-3282(01)00462-8 1:STN:280:DC%2BD3MzmsFSgtg%3D%3D 11425651 (Pubitemid 32577379)
20. W Yao T Hadi Y Jiang, et al. 2005 Basic fibroblast growth factor improves trabecular bone connectivity and bone strength in the lumbar vertebral body of osteopenic rats Osteoporos Int 16 1939 1947 10.1007/s00198-005-1969-2 1:CAS:528:DC%2BD2MXhtlWkt7zE 16086094 (Pubitemid 41790911)
21. HZ Ke VW Shen H QI, et al. 1998 Prostaglandin E2 increase bone strength in intact rats and in ovarectomized rats with established osteopenia Bone 23 249 255 10.1016/S8756-3282(98)00102-1 1:CAS:528:DyaK1cXlvF2hurg%3D 9737347 (Pubitemid 28434669)
22. L Mosekilde JS Thomsen PB Orhii, et al. 1999 Additive effect of voluntary exercise and growth hormone treatment on bone strength assessed at four different skeletal sites in an aged rat model Bone 24 71 80 10.1016/S8756- 3282(98)00169-0 1:CAS:528:DyaK1MXhtVejtrk%3D 9951773 (Pubitemid 29070796)
23. D Chachra M Kasra CM Vanin, et al. 1995 The effect of different hormone replacement therapy regimes on the mechanical properties of rat vertebra Calcif Tissue Int 56 130 134 10.1007/BF00296344 1:CAS:528:DyaK2MXkvVylu7k%3D 7736321
24. SM Verschueren M Roelants C Delecluse, et al. 2004 Effect of 6-month whole body vibration training on hip density, muscle strength, and postural control in postmenopausal women: a randomized controlled pilot study J Bone Miner Res 19 352 359 10.1359/JBMR.0301245 15040822 (Pubitemid 38787389)
25. C Rubin R Recker D Cullen, et al. 2004 Prevention of postmenopausal bone loss by a low-magnitude, high-frequency mechanical stimuli: a clinical trial assessing compliance, efficacy, and safety J Bone Miner Res 19 343 351 10.1359/JBMR.0301251 15040821 (Pubitemid 38787388)
26. V Gilsanz TA Wren M Sanchez, et al. 2006 Low-level, high-frequency mechanical signals enhance musculoskeletal development of young women with low BMD J Bone Miner Res 21 1464 1474 10.1359/jbmr.060612 16939405 (Pubitemid 44300053)
27. A Rubinacci M Marenzana F Cavani, et al. 2008 Ovariectomy sensitizes rat cortical bone to whole-body vibration Calcif Tissue Int 82 316 326 10.1007/s00223-008-9115-8 1:CAS:528:DC%2BD1cXlt1Cqtbw%3D 18379712 (Pubitemid 351624501)
28. KC Lee H Jessop R Suswillo, et al. 2004 The adaptive response of bone to mechanical loading in female transgenic mice is deficient in the absence of oestrogen receptor-alpha and -beta J Endocrinol 182 193 201 10.1677/joe.0. 1820193 1:CAS:528:DC%2BD2cXntFOgt7s%3D 15283680 (Pubitemid 39199003)
29. LK Saxon CH Turner 2005 Estrogen receptor beta: the antimechanostat? Bone 36 185 192 10.1016/j.bone.2004.08.003 1:CAS:528:DC%2BD2MXhslWks70%3D 15780944 (Pubitemid 40283575)
30. S Torvinen P Kannus H Sievänen, et al. 2003 Effect of 8-month vertical whole body vibration on bone, muscle performance, and body balance: a randomized controlled study J Bone Miner Res 18 876 884 10.1359/jbmr.2003.18.5. 876 12733727 (Pubitemid 37294971)
31. G Karsenty 2003 The complexities of skeletal biology Nature 423 316 318 10.1038/nature01654 1:CAS:528:DC%2BD3sXjs1ynu7w%3D 12748648 (Pubitemid 40852704)
32. S Judex R Garman M Squire, et al. 2004 Genetically linked site-specificity of disuse osteoporosis J Bone Miner Res 19 607 613 10.1359/JBMR.040110 15005848 (Pubitemid 41071221)
33. DB Burr MR Forwood DP Fyhrie, et al. 1997 Bone microdamage and skeletal fragility in osteoporotic and stress fractures J Bone Miner Res 12 6 15 10.1359/jbmr.1997.12.1.6 1:STN:280:DyaK2szot1OgtQ%3D%3D 9240720 (Pubitemid 27053606)
34. JA Eisman 2001 Good, good, good⋯ good vibrations: the best option for better bones? Lancet 358 1924 1925 10.1016/S0140-6736(01)06975-6 1:STN:280:DC%2BD3MnpvFalsg%3D%3D 11747912 (Pubitemid 34072869)
35. SP Fritton KJ McLeod CT Rubin 2000 Quantifying the strain history of bone: spatial uniformity and self-similarity of low-magnitude strains J Biomech 33 317 325 10.1016/S0021-9290(99)00210-9 1:STN:280:DC%2BD3c7jsFKksg%3D%3D 10673115
36. RL Duncan CH Turner 1995 Mechanotransduction and the functional response of bone to mechanical strain Calcif Tissue Int 57 344 358 10.1007/BF00302070 1:CAS:528:DyaK2MXovVart7o%3D 8564797
37. SJ Warden CH Turner 2004 Mechanotransduction in the cortical bone is most efficient at loading frequencies of 5-10 Hz Bone 34 261 270 10.1016/j.bone.2003.11.011 1:STN:280:DC%2BD2c%2FntlCmsA%3D%3D 14962804 (Pubitemid 38177607)
38. R Garman C Rubin S Judex 2007 Small oscillatory accelerations, independent of matrix deformations, increase osteoblast activity and enhance bone morphology PLoS ONE 25 e653 10.1371/journal.pone.0000653 (Pubitemid 351308766)
39. AB Castillo I Alam SM Tanaka, et al. 2006 Low-amplitude, broad-frequency vibration effects on cortical bone formation in mice Bone 39 1087 1096 10.1016/j.bone.2006.04.026 16793358 (Pubitemid 44528371)
40. SR Cummings MC Nevitt WS Browner, et al. 1995 Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group N Engl J Med 332 767 773 10.1056/NEJM199503233321202 1:STN:280:DyaK2M7ms1aktw%3D%3D 7862179