Terpenoids. III: Synthesis and biological evaluation of 23-hydroxybetulinic acid derivatives as novel inhibitors of glycogen phosphorylase

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 24, 2009, Pages 6966-6969

  Zhu, Peiqing ^a   Bi, Yi ^a   Xu, Jinyi ^a   Li, Zan ^a   Liu, Jun ^a   Zhang, Luyong ^a   Ye, Wencai ^a   Wu, Xiaoming ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

23 Hydroxybetulinic acid; Biological evaluation; Glycogen phosphorylase inhibitor; SAR

Indexed keywords

23 HYDROXYBETULINIC ACID DERIVATIVE; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; GLYCOGEN PHOSPHORYLASE; GLYCOSYLTRANSFERASE INHIBITOR; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; GLYCOGEN METABOLISM; IC 50; IN VITRO STUDY; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; DRUG DESIGN; ENZYME INHIBITORS; GLYCOGEN PHOSPHORYLASE; HUMANS; RABBITS; STRUCTURE-ACTIVITY RELATIONSHIP; TRITERPENES;

EID: 71849096607     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.10.055     Document Type: Article

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