메뉴 건너뛰기




Volumn 67, Issue 1, 2010, Pages 4-11

Skeletal morbidity in lung cancer patients with bone metastases: Demonstrating the need for early diagnosis and treatment with bisphosphonates

Author keywords

Bisphosphonates; Bone metastases; Non small cell lung cancer; Zoledronic acid

Indexed keywords

ALENDRONIC ACID; ALKALINE PHOSPHATASE BONE ISOENZYME; AMINO TERMINAL TELOPEPTIDE; BISPHOSPHONIC ACID DERIVATIVE; CARBOPLATIN; CISPLATIN; CLODRONIC ACID; DOCETAXEL; ETIDRONIC ACID; FLUORODEOXYGLUCOSE F 18; IBANDRONIC ACID; PACLITAXEL; PAMIDRONIC ACID; PLACEBO; RISEDRONIC ACID; ZOLEDRONIC ACID;

EID: 71849091513     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2009.08.020     Document Type: Review
Times cited : (78)

References (78)
  • 1
    • 33750700477 scopus 로고    scopus 로고
    • Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study
    • Giaccone G., Gallegos Ruiz M., Le Chevalier T., et al. Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study. Clin Cancer Res 12 (2006) 6049-6055
    • (2006) Clin Cancer Res , vol.12 , pp. 6049-6055
    • Giaccone, G.1    Gallegos Ruiz, M.2    Le Chevalier, T.3
  • 2
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • Sandler A., Gray R., Perry M.C., et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 355 (2006) 2542-2550
    • (2006) N Engl J Med , vol.355 , pp. 2542-2550
    • Sandler, A.1    Gray, R.2    Perry, M.C.3
  • 3
    • 0035010803 scopus 로고    scopus 로고
    • Metastatic bone disease: clinical features, pathophysiology and treatment strategies
    • Coleman R.E. Metastatic bone disease: clinical features, pathophysiology and treatment strategies. Cancer Treat Rev 27 (2001) 165-176
    • (2001) Cancer Treat Rev , vol.27 , pp. 165-176
    • Coleman, R.E.1
  • 4
    • 33947493715 scopus 로고    scopus 로고
    • Is there a role of whole body bone scan in early stages of non small cell lung cancer patients
    • Iordanidou L., Trivizaki E., Saranti S., et al. Is there a role of whole body bone scan in early stages of non small cell lung cancer patients. J BUON 11 (2006) 491-497
    • (2006) J BUON , vol.11 , pp. 491-497
    • Iordanidou, L.1    Trivizaki, E.2    Saranti, S.3
  • 5
    • 33244483921 scopus 로고    scopus 로고
    • Computed tomography screening for lung cancer: applicability of an international protocol in a single-institution environment
    • Shaham D., Breuer R., Copel L., et al. Computed tomography screening for lung cancer: applicability of an international protocol in a single-institution environment. Clin Lung Cancer 7 (2006) 262-267
    • (2006) Clin Lung Cancer , vol.7 , pp. 262-267
    • Shaham, D.1    Breuer, R.2    Copel, L.3
  • 6
    • 0042914647 scopus 로고    scopus 로고
    • Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: a phase III, double-blind, randomized trial-the Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group
    • Rosen L.S., Gordon D., Tchekmedyian S., et al. Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: a phase III, double-blind, randomized trial-the Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group. J Clin Oncol 21 (2003) 3150-3157
    • (2003) J Clin Oncol , vol.21 , pp. 3150-3157
    • Rosen, L.S.1    Gordon, D.2    Tchekmedyian, S.3
  • 7
    • 0012381722 scopus 로고    scopus 로고
    • Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (the IDEAL 1 trial)
    • [corrected]
    • Fukuoka M., Yano S., Giaccone G., et al. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (the IDEAL 1 trial). J Clin Oncol 21 (2003) 2237-2246 [corrected]
    • (2003) J Clin Oncol , vol.21 , pp. 2237-2246
    • Fukuoka, M.1    Yano, S.2    Giaccone, G.3
  • 8
    • 33751091232 scopus 로고    scopus 로고
    • Managing bone complications of solid tumors
    • Berenson J.R., Rajdev L., and Broder M. Managing bone complications of solid tumors. Cancer Biol Ther 5 (2006) 1086-1089
    • (2006) Cancer Biol Ther , vol.5 , pp. 1086-1089
    • Berenson, J.R.1    Rajdev, L.2    Broder, M.3
  • 9
    • 0033663602 scopus 로고    scopus 로고
    • Management of bone metastases
    • Coleman R.E. Management of bone metastases. Oncologist 5 (2000) 463-470
    • (2000) Oncologist , vol.5 , pp. 463-470
    • Coleman, R.E.1
  • 10
    • 5444262558 scopus 로고    scopus 로고
    • Bisphosphonates: clinical experience
    • Coleman R.E. Bisphosphonates: clinical experience. Oncologist 9 suppl. 4 (2004) 14-27
    • (2004) Oncologist , vol.9 , Issue.SUPPL. 4 , pp. 14-27
    • Coleman, R.E.1
  • 11
    • 0037301981 scopus 로고    scopus 로고
    • Mechanisms of osteolytic bone metastases in breast carcinoma
    • Kakonen S.M., and Mundy G.R. Mechanisms of osteolytic bone metastases in breast carcinoma. Cancer 97 suppl. (2003) 834-839
    • (2003) Cancer , vol.97 , Issue.SUPPL , pp. 834-839
    • Kakonen, S.M.1    Mundy, G.R.2
  • 12
    • 33750738067 scopus 로고    scopus 로고
    • Basic mechanisms responsible for osteolytic and osteoblastic bone metastases
    • Guise T.A., Mohammad K.S., Clines G., et al. Basic mechanisms responsible for osteolytic and osteoblastic bone metastases. Clin Cancer Res 12 suppl. (2006) 6213s-6216
    • (2006) Clin Cancer Res , vol.12 , Issue.SUPPL
    • Guise, T.A.1    Mohammad, K.S.2    Clines, G.3
  • 13
    • 0034659929 scopus 로고    scopus 로고
    • Molecular basis of the spectrum of skeletal complications of neoplasia
    • Goltzman D., Karaplis A.C., Kremer R., and Rabbani S.A. Molecular basis of the spectrum of skeletal complications of neoplasia. Cancer 88 suppl. (2000) 2903-2908
    • (2000) Cancer , vol.88 , Issue.SUPPL , pp. 2903-2908
    • Goltzman, D.1    Karaplis, A.C.2    Kremer, R.3    Rabbani, S.A.4
  • 15
    • 2642521168 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: a randomized, phase III, double-blind, placebo-controlled trial
    • Rosen L.S., Gordon D., Tchekmedyian N.S., et al. Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: a randomized, phase III, double-blind, placebo-controlled trial. Cancer 100 (2004) 2613-2621
    • (2004) Cancer , vol.100 , pp. 2613-2621
    • Rosen, L.S.1    Gordon, D.2    Tchekmedyian, N.S.3
  • 16
    • 4644239072 scopus 로고    scopus 로고
    • Pathophysiology of bone metastases: how this knowledge may lead to therapeutic intervention
    • [discussion follows]
    • Lipton A. Pathophysiology of bone metastases: how this knowledge may lead to therapeutic intervention. J Support Oncol 2 (2004) 205-213 [discussion follows]
    • (2004) J Support Oncol , vol.2 , pp. 205-213
    • Lipton, A.1
  • 17
    • 10744233021 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trial
    • Rosen L.S., Gordon D., Kaminski M., et al. Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trial. Cancer 98 (2003) 1735-1744
    • (2003) Cancer , vol.98 , pp. 1735-1744
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 18
    • 2942518111 scopus 로고    scopus 로고
    • Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer
    • Saad F., Gleason D.M., Murray R., et al. Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer. J Natl Cancer Inst 96 (2004) 879-882
    • (2004) J Natl Cancer Inst , vol.96 , pp. 879-882
    • Saad, F.1    Gleason, D.M.2    Murray, R.3
  • 19
    • 10244250263 scopus 로고    scopus 로고
    • Clinical benefit of zoledronic acid in patients with lung cancer and other solid tumors: analysis based on history of skeletal complications
    • Hirsh V., Tchekmedyian N.S., Rosen L.S., Zheng M., and Hei Y.J. Clinical benefit of zoledronic acid in patients with lung cancer and other solid tumors: analysis based on history of skeletal complications. Clin Lung Cancer 6 (2004) 170-174
    • (2004) Clin Lung Cancer , vol.6 , pp. 170-174
    • Hirsh, V.1    Tchekmedyian, N.S.2    Rosen, L.S.3    Zheng, M.4    Hei, Y.J.5
  • 20
    • 0642342669 scopus 로고    scopus 로고
    • American Society of Clinical Oncology 2003 update on the role of bisphosphonates and bone health issues in women with breast cancer
    • Hillner B.E., Ingle J.N., Chlebowski R.T., et al. American Society of Clinical Oncology 2003 update on the role of bisphosphonates and bone health issues in women with breast cancer. J Clin Oncol 21 (2003) 4042-4057
    • (2003) J Clin Oncol , vol.21 , pp. 4042-4057
    • Hillner, B.E.1    Ingle, J.N.2    Chlebowski, R.T.3
  • 22
    • 0030879065 scopus 로고    scopus 로고
    • Mechanisms of bone metastasis
    • Mundy G.R. Mechanisms of bone metastasis. Cancer 80 suppl. (1997) 1546-1556
    • (1997) Cancer , vol.80 , Issue.SUPPL , pp. 1546-1556
    • Mundy, G.R.1
  • 23
    • 0345734350 scopus 로고    scopus 로고
    • Role of bisphosphonates in prostate cancer
    • Saad F., and Schulman C.C. Role of bisphosphonates in prostate cancer. Eur Urol 45 (2004) 26-34
    • (2004) Eur Urol , vol.45 , pp. 26-34
    • Saad, F.1    Schulman, C.C.2
  • 24
    • 15544366136 scopus 로고    scopus 로고
    • Pathophysiology of bone cancer pain
    • Sabino M.A., and Mantyh P.W. Pathophysiology of bone cancer pain. J Support Oncol 3 (2005) 15-24
    • (2005) J Support Oncol , vol.3 , pp. 15-24
    • Sabino, M.A.1    Mantyh, P.W.2
  • 25
    • 1342268525 scopus 로고    scopus 로고
    • American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003
    • Pfister D.G., Johnson D.H., Azzoli C.G., et al. American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003. J Clin Oncol 22 (2004) 330-353
    • (2004) J Clin Oncol , vol.22 , pp. 330-353
    • Pfister, D.G.1    Johnson, D.H.2    Azzoli, C.G.3
  • 26
    • 4544273775 scopus 로고    scopus 로고
    • Position of nuclear medicine modalities in the diagnostic workup of cancer patients: lung cancer
    • Baum R.P., Hellwig D., and Mezzetti M. Position of nuclear medicine modalities in the diagnostic workup of cancer patients: lung cancer. Q J Nucl Med Mol Imaging 48 (2004) 119-142
    • (2004) Q J Nucl Med Mol Imaging , vol.48 , pp. 119-142
    • Baum, R.P.1    Hellwig, D.2    Mezzetti, M.3
  • 27
    • 0037249628 scopus 로고    scopus 로고
    • The noninvasive staging of non-small cell lung cancer: the guidelines
    • Silvestri G.A., Tanoue L.T., Margolis M.L., Barker J., and Detterbeck F. The noninvasive staging of non-small cell lung cancer: the guidelines. Chest 123 suppl. (2003) 147S-156S
    • (2003) Chest , vol.123 , Issue.SUPPL
    • Silvestri, G.A.1    Tanoue, L.T.2    Margolis, M.L.3    Barker, J.4    Detterbeck, F.5
  • 29
    • 0031664230 scopus 로고    scopus 로고
    • Fluorine-18 deoxyglucose positron emission tomography for the detection of bone metastases in patients with non-small cell lung cancer
    • Bury T., Barreto A., Daenen F., et al. Fluorine-18 deoxyglucose positron emission tomography for the detection of bone metastases in patients with non-small cell lung cancer. Eur J Nucl Med 25 (1998) 1244-1247
    • (1998) Eur J Nucl Med , vol.25 , pp. 1244-1247
    • Bury, T.1    Barreto, A.2    Daenen, F.3
  • 30
    • 0038584863 scopus 로고    scopus 로고
    • Comparison of bone and 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography in the evaluation of bony metastases in lung cancer
    • Gayed I., Vu T., Johnson M., Macapinlac H., and Podoloff D. Comparison of bone and 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography in the evaluation of bony metastases in lung cancer. Mol Imaging Biol 5 (2003) 26-31
    • (2003) Mol Imaging Biol , vol.5 , pp. 26-31
    • Gayed, I.1    Vu, T.2    Johnson, M.3    Macapinlac, H.4    Podoloff, D.5
  • 31
    • 10744226515 scopus 로고    scopus 로고
    • F-18 NaF PET for detection of bone metastases in lung cancer: accuracy, cost-effectiveness, and impact on patient management
    • Hetzel M., Arslandemir C., Konig H.H., et al. F-18 NaF PET for detection of bone metastases in lung cancer: accuracy, cost-effectiveness, and impact on patient management. J Bone Miner Res 18 (2003) 2206-2214
    • (2003) J Bone Miner Res , vol.18 , pp. 2206-2214
    • Hetzel, M.1    Arslandemir, C.2    Konig, H.H.3
  • 32
    • 0034162528 scopus 로고    scopus 로고
    • Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: long term follow-up of two randomized, placebo-controlled trials
    • Lipton A., Theriault R.L., Hortobagyi G.N., et al. Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: long term follow-up of two randomized, placebo-controlled trials. Cancer 88 (2000) 1082-1090
    • (2000) Cancer , vol.88 , pp. 1082-1090
    • Lipton, A.1    Theriault, R.L.2    Hortobagyi, G.N.3
  • 33
    • 6844252283 scopus 로고    scopus 로고
    • Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group
    • Berenson J.R., Lichtenstein A., Porter L., et al. Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group. J Clin Oncol 16 (1998) 593-602
    • (1998) J Clin Oncol , vol.16 , pp. 593-602
    • Berenson, J.R.1    Lichtenstein, A.2    Porter, L.3
  • 34
    • 22544442188 scopus 로고    scopus 로고
    • Clinical benefit of zoledronic acid for the prevention of skeletal complications in advanced prostate cancer
    • Saad F. Clinical benefit of zoledronic acid for the prevention of skeletal complications in advanced prostate cancer. Clin Prostate Cancer 4 (2005) 31-37
    • (2005) Clin Prostate Cancer , vol.4 , pp. 31-37
    • Saad, F.1
  • 35
    • 0346186206 scopus 로고    scopus 로고
    • Bisphosphonate therapy in the oncology setting
    • Lipton A. Bisphosphonate therapy in the oncology setting. Expert Opin Emerg Drugs 8 2 (2003) 469-488
    • (2003) Expert Opin Emerg Drugs , vol.8 , Issue.2 , pp. 469-488
    • Lipton, A.1
  • 36
    • 18744364348 scopus 로고    scopus 로고
    • Cost of skeletal complications in patients with bone metastases of lung cancer [abstract]
    • [Abstract O9]
    • Delea T., McKiernan J., Liss M., et al. Cost of skeletal complications in patients with bone metastases of lung cancer [abstract]. Lung Cancer 41 suppl. 2 (2003) S7 [Abstract O9]
    • (2003) Lung Cancer , vol.41 , Issue.SUPPL. 2
    • Delea, T.1    McKiernan, J.2    Liss, M.3
  • 37
    • 13844314054 scopus 로고    scopus 로고
    • The cost of treatment of skeletal-related events in patients with bone metastases from lung cancer
    • Delea T., Langer C., McKiernan J., et al. The cost of treatment of skeletal-related events in patients with bone metastases from lung cancer. Oncology 67 (2004) 390-396
    • (2004) Oncology , vol.67 , pp. 390-396
    • Delea, T.1    Langer, C.2    McKiernan, J.3
  • 38
    • 18344382788 scopus 로고    scopus 로고
    • The role of bisphosphonates in the management of advanced cancer with a focus on non-small-cell lung cancer. Part 2: Clinical studies and economic analyses
    • Saba N., and Khuri F. The role of bisphosphonates in the management of advanced cancer with a focus on non-small-cell lung cancer. Part 2: Clinical studies and economic analyses. Oncology 68 (2005) 18-22
    • (2005) Oncology , vol.68 , pp. 18-22
    • Saba, N.1    Khuri, F.2
  • 39
    • 0034565060 scopus 로고    scopus 로고
    • Malignant bone pain: pathophysiology and treatments
    • Ripamonti C., and Fulfaro F. Malignant bone pain: pathophysiology and treatments. Curr Rev Pain 4 (2000) 187-196
    • (2000) Curr Rev Pain , vol.4 , pp. 187-196
    • Ripamonti, C.1    Fulfaro, F.2
  • 40
    • 35048875471 scopus 로고    scopus 로고
    • Pathologic fractures correlate with reduced survival in patients with malignant bone disease
    • Saad F., Lipton A., Cook R., et al. Pathologic fractures correlate with reduced survival in patients with malignant bone disease. Cancer 110 (2007) 1860-1867
    • (2007) Cancer , vol.110 , pp. 1860-1867
    • Saad, F.1    Lipton, A.2    Cook, R.3
  • 41
    • 18144427879 scopus 로고    scopus 로고
    • The significance of skeletal-related events for the health-related quality of life of patients with metastatic prostate cancer
    • Weinfurt K.P., Li Y., Castel L.D., et al. The significance of skeletal-related events for the health-related quality of life of patients with metastatic prostate cancer. Ann Oncol 16 (2005) 579-584
    • (2005) Ann Oncol , vol.16 , pp. 579-584
    • Weinfurt, K.P.1    Li, Y.2    Castel, L.D.3
  • 42
    • 34247890126 scopus 로고    scopus 로고
    • Impact of skeletal complications on total medical care costs among patients with bone metastases of lung cancer
    • Delea T.E., McKiernan J., Brandman J., et al. Impact of skeletal complications on total medical care costs among patients with bone metastases of lung cancer. J Thorac Oncol 1 (2006) 571-576
    • (2006) J Thorac Oncol , vol.1 , pp. 571-576
    • Delea, T.E.1    McKiernan, J.2    Brandman, J.3
  • 43
    • 71849086881 scopus 로고    scopus 로고
    • Preclinical profile and anticancer potential of zoledronic acid
    • Birch E.V. (Ed), Nova Science Publishers, Inc, New York
    • Green J.R. Preclinical profile and anticancer potential of zoledronic acid. In: Birch E.V. (Ed). Trends in bone cancer research 24 (2006), Nova Science Publishers, Inc, New York 217-245
    • (2006) Trends in bone cancer research , vol.24 , pp. 217-245
    • Green, J.R.1
  • 44
    • 0036148405 scopus 로고    scopus 로고
    • Development of bisphosphonates
    • Fleisch H. Development of bisphosphonates. Breast Cancer Res 4 (2002) 30-34
    • (2002) Breast Cancer Res , vol.4 , pp. 30-34
    • Fleisch, H.1
  • 45
    • 5444242637 scopus 로고    scopus 로고
    • Bisphosphonates: preclinical review
    • Green J.R. Bisphosphonates: preclinical review. Oncologist 9 suppl. 4 (2004) 3-13
    • (2004) Oncologist , vol.9 , Issue.SUPPL. 4 , pp. 3-13
    • Green, J.R.1
  • 46
    • 0030225550 scopus 로고    scopus 로고
    • Zoledronate: the preclinical pharmacology
    • [discussion follows]
    • Green J. Zoledronate: the preclinical pharmacology. Br J Clin Pract Suppl 87 (1996) 16-18 [discussion follows]
    • (1996) Br J Clin Pract Suppl , vol.87 , pp. 16-18
    • Green, J.1
  • 47
    • 0028202499 scopus 로고
    • Preclinical pharmacology of CGP 42'446, a new, potent, heterocyclic bisphosphonate compound
    • Green J.R., Muller K., and Jaeggi K.A. Preclinical pharmacology of CGP 42'446, a new, potent, heterocyclic bisphosphonate compound. J Bone Miner Res 9 (1994) 745-751
    • (1994) J Bone Miner Res , vol.9 , pp. 745-751
    • Green, J.R.1    Muller, K.2    Jaeggi, K.A.3
  • 48
    • 84944590106 scopus 로고    scopus 로고
    • Long-term therapy with zoledronic acid is effective and safe in reducing the risk of skeletal complications in patients with bone metastases from non-small cell lung cancer (NSCLC) [poster]
    • August 10-14, Vancouver, British Columbia, Canada [Abstract 150]
    • Bukowski R., Rosen L., Gordon D., et al. Long-term therapy with zoledronic acid is effective and safe in reducing the risk of skeletal complications in patients with bone metastases from non-small cell lung cancer (NSCLC) [poster]. 10th World Conference on Lung Cancer. August 10-14, Vancouver, British Columbia, Canada (2003) [Abstract 150]
    • (2003) 10th World Conference on Lung Cancer
    • Bukowski, R.1    Rosen, L.2    Gordon, D.3
  • 49
    • 5444243800 scopus 로고    scopus 로고
    • Safety of intravenous and oral bisphosphonates and compliance with dosing regimens
    • Conte P., and Guarneri V. Safety of intravenous and oral bisphosphonates and compliance with dosing regimens. Oncologist 9 suppl. 4 (2004) 28-37
    • (2004) Oncologist , vol.9 , Issue.SUPPL. 4 , pp. 28-37
    • Conte, P.1    Guarneri, V.2
  • 50
    • 34147095972 scopus 로고    scopus 로고
    • Critical review: updated recommendations for the prevention, diagnosis, and treatment of osteonecrosis of the jaw in cancer patients-May 2006
    • Weitzman R., Sauter N., Eriksen E.F., et al. Critical review: updated recommendations for the prevention, diagnosis, and treatment of osteonecrosis of the jaw in cancer patients-May 2006. Crit Rev Oncol Hematol 62 (2007) 148-152
    • (2007) Crit Rev Oncol Hematol , vol.62 , pp. 148-152
    • Weitzman, R.1    Sauter, N.2    Eriksen, E.F.3
  • 51
    • 71849090227 scopus 로고    scopus 로고
    • Zometa [package insert, East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2005
    • Zometa [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2005.
  • 52
    • 21444449880 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw and bisphosphonates
    • [discussion follows]
    • Durie B.G., Katz M., and Crowley J. Osteonecrosis of the jaw and bisphosphonates. N Engl J Med 353 (2005) 99-102 [discussion follows]
    • (2005) N Engl J Med , vol.353 , pp. 99-102
    • Durie, B.G.1    Katz, M.2    Crowley, J.3
  • 53
    • 44449153039 scopus 로고    scopus 로고
    • Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonates
    • Hoff A.O., Toth B.B., Altundag K., et al. Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonates. J Bone Miner Res 23 (2008) 826-836
    • (2008) J Bone Miner Res , vol.23 , pp. 826-836
    • Hoff, A.O.1    Toth, B.B.2    Altundag, K.3
  • 54
    • 34247218044 scopus 로고    scopus 로고
    • Bisphosphonate-associated osteonecrosis of the jaw: a review of 35 cases and an evaluation of its frequency in multiple myeloma patients
    • Pozzi S., Marcheselli R., Sacchi S., et al. Bisphosphonate-associated osteonecrosis of the jaw: a review of 35 cases and an evaluation of its frequency in multiple myeloma patients. Leuk Lymphoma 48 (2007) 56-64
    • (2007) Leuk Lymphoma , vol.48 , pp. 56-64
    • Pozzi, S.1    Marcheselli, R.2    Sacchi, S.3
  • 55
    • 58949104001 scopus 로고    scopus 로고
    • Reduction of osteonecrosis of the jaw (ONJ) after implementation of preventive measures in patients with multiple myeloma treated with zoledronic acid
    • Dimopoulos M.A., Kastritis E., Bamia C., et al. Reduction of osteonecrosis of the jaw (ONJ) after implementation of preventive measures in patients with multiple myeloma treated with zoledronic acid. Ann Oncol 20 (2009) 117-120
    • (2009) Ann Oncol , vol.20 , pp. 117-120
    • Dimopoulos, M.A.1    Kastritis, E.2    Bamia, C.3
  • 56
    • 57049173860 scopus 로고    scopus 로고
    • Antibiotic prophylaxis before dental procedures may reduce the incidence of osteonecrosis of the jaw in patients with multiple myeloma treated with bisphosphonates
    • Montefusco V., Gay F., Spina F., et al. Antibiotic prophylaxis before dental procedures may reduce the incidence of osteonecrosis of the jaw in patients with multiple myeloma treated with bisphosphonates. Leuk Lymphoma 49 (2008) 2156-2162
    • (2008) Leuk Lymphoma , vol.49 , pp. 2156-2162
    • Montefusco, V.1    Gay, F.2    Spina, F.3
  • 57
    • 58949093771 scopus 로고    scopus 로고
    • Decreased occurrence of osteonecrosis of the jaw after implementation of dental preventive measures in solid tumour patients with bone metastases treated with bisphosphonates. The experience of the National Cancer Institute of Milan
    • Ripamonti C.I., Maniezzo M., Campa T., et al. Decreased occurrence of osteonecrosis of the jaw after implementation of dental preventive measures in solid tumour patients with bone metastases treated with bisphosphonates. The experience of the National Cancer Institute of Milan. Ann Oncol 20 (2009) 137-145
    • (2009) Ann Oncol , vol.20 , pp. 137-145
    • Ripamonti, C.I.1    Maniezzo, M.2    Campa, T.3
  • 58
    • 71849097937 scopus 로고    scopus 로고
    • Medical ozone oil suspension applications heal osteonecrosis of the jaw (ONJ) in patients treated with bisphosphonates (BPs): preliminary results of a single institution protocol [poster]
    • March 11-14, St. Gallen, Switzerland [Poster 194]
    • Ripamonti C., Maniezzo M., Ghiringhelli R., et al. Medical ozone oil suspension applications heal osteonecrosis of the jaw (ONJ) in patients treated with bisphosphonates (BPs): preliminary results of a single institution protocol [poster]. Primary Therapy of Early Breast Cancer 11th International Conference. March 11-14, St. Gallen, Switzerland (2009) [Poster 194]
    • (2009) Primary Therapy of Early Breast Cancer 11th International Conference
    • Ripamonti, C.1    Maniezzo, M.2    Ghiringhelli, R.3
  • 59
    • 19944432878 scopus 로고    scopus 로고
    • Bone turnover markers as predictors of skeletal complications in prostate cancer, lung cancer, and other solid tumors
    • Brown J.E., Cook R.J., Major P., et al. Bone turnover markers as predictors of skeletal complications in prostate cancer, lung cancer, and other solid tumors. J Natl Cancer Inst 97 (2005) 59-69
    • (2005) J Natl Cancer Inst , vol.97 , pp. 59-69
    • Brown, J.E.1    Cook, R.J.2    Major, P.3
  • 60
    • 17444391717 scopus 로고    scopus 로고
    • Clinical value of bone remodelling markers in patients with bone metastases treated with zoledronic acid
    • Pectasides D., Nikolaou M., Farmakis D., et al. Clinical value of bone remodelling markers in patients with bone metastases treated with zoledronic acid. Anticancer Res 25 (2005) 1457-1463
    • (2005) Anticancer Res , vol.25 , pp. 1457-1463
    • Pectasides, D.1    Nikolaou, M.2    Farmakis, D.3
  • 61
    • 24644479228 scopus 로고    scopus 로고
    • Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid
    • Coleman R.E., Major P., Lipton A., et al. Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid. J Clin Oncol 23 (2005) 4925-4935
    • (2005) J Clin Oncol , vol.23 , pp. 4925-4935
    • Coleman, R.E.1    Major, P.2    Lipton, A.3
  • 62
    • 47149118386 scopus 로고    scopus 로고
    • Normalization of bone markers is associated with improved survival in patients with bone metastases from solid tumors and elevated bone resorption receiving zoledronic acid
    • Lipton A., Cook R., Saad F., et al. Normalization of bone markers is associated with improved survival in patients with bone metastases from solid tumors and elevated bone resorption receiving zoledronic acid. Cancer 113 (2008) 193-201
    • (2008) Cancer , vol.113 , pp. 193-201
    • Lipton, A.1    Cook, R.2    Saad, F.3
  • 63
    • 43249128301 scopus 로고    scopus 로고
    • Zoledronic acid and survival in patients with metastatic bone disease from lung cancer and elevated markers of osteoclast activity
    • Hirsh V., Major P.P., Lipton A., et al. Zoledronic acid and survival in patients with metastatic bone disease from lung cancer and elevated markers of osteoclast activity. J Thorac Oncol 3 (2008) 228-236
    • (2008) J Thorac Oncol , vol.3 , pp. 228-236
    • Hirsh, V.1    Major, P.P.2    Lipton, A.3
  • 64
    • 0037304115 scopus 로고    scopus 로고
    • Antitumor effects of bisphosphonates
    • Green J.R. Antitumor effects of bisphosphonates. Cancer 97 suppl. (2003) 840-847
    • (2003) Cancer , vol.97 , Issue.SUPPL , pp. 840-847
    • Green, J.R.1
  • 65
    • 5444255958 scopus 로고    scopus 로고
    • Efficacy of combining the third generation bisphosphonate, zoledronate with imatinib mesylate in suppressing small cell lung cancer cell line proliferation [abstract]
    • [Abstract 2750]
    • Matsumoto S., Kimura S., Segawa H., et al. Efficacy of combining the third generation bisphosphonate, zoledronate with imatinib mesylate in suppressing small cell lung cancer cell line proliferation [abstract]. Proc Am Soc Clin Oncol 22 suppl. (2003) 684 [Abstract 2750]
    • (2003) Proc Am Soc Clin Oncol , vol.22 , Issue.SUPPL , pp. 684
    • Matsumoto, S.1    Kimura, S.2    Segawa, H.3
  • 66
    • 79551506156 scopus 로고    scopus 로고
    • The N-containing bisphosphonate zoledronic acid exerts potent anticancer activity against non-small cell lung cancer cells by inhibition of protein geranylgeranylation [abstract]
    • [Abstract 4981]
    • Berger W., Kubista B., Elbling L., Sutterluty H., and Micksche M. The N-containing bisphosphonate zoledronic acid exerts potent anticancer activity against non-small cell lung cancer cells by inhibition of protein geranylgeranylation [abstract]. Proc Am Assoc Cancer Res 46 (2005) [Abstract 4981]
    • (2005) Proc Am Assoc Cancer Res , vol.46
    • Berger, W.1    Kubista, B.2    Elbling, L.3    Sutterluty, H.4    Micksche, M.5
  • 67
    • 34249286243 scopus 로고    scopus 로고
    • Cisplatin cytotoxicity is enhanced with zoledronic acid in A549 lung cancer cell line: preliminary results of an in vitro study
    • Ozturk O.H., Bozcuk H., Burgucu D., et al. Cisplatin cytotoxicity is enhanced with zoledronic acid in A549 lung cancer cell line: preliminary results of an in vitro study. Cell Biol Int 31 (2007) 1069-1071
    • (2007) Cell Biol Int , vol.31 , pp. 1069-1071
    • Ozturk, O.H.1    Bozcuk, H.2    Burgucu, D.3
  • 68
    • 71849106584 scopus 로고    scopus 로고
    • Zoledronic acid synergizes with Taxol in an HDAC6-dependent manner: novel mechanistic implications for combination anticancer therapy with taxanes [abstract]
    • [Abstract 1425]
    • Gjyrezi A., O'Brate A., Chanel-Vos C., and Giannakakou P. Zoledronic acid synergizes with Taxol in an HDAC6-dependent manner: novel mechanistic implications for combination anticancer therapy with taxanes [abstract]. Proc Am Assoc Cancer Res (2007) [Abstract 1425]
    • (2007) Proc Am Assoc Cancer Res
    • Gjyrezi, A.1    O'Brate, A.2    Chanel-Vos, C.3    Giannakakou, P.4
  • 69
    • 38749122501 scopus 로고    scopus 로고
    • Zoledronic acid is unable to induce apoptosis, but slows tumor growth and prolongs survival for non-small-cell lung cancers
    • Li Y.Y., Chang J.W., Chou W.C., et al. Zoledronic acid is unable to induce apoptosis, but slows tumor growth and prolongs survival for non-small-cell lung cancers. Lung Cancer 59 (2008) 180-191
    • (2008) Lung Cancer , vol.59 , pp. 180-191
    • Li, Y.Y.1    Chang, J.W.2    Chou, W.C.3
  • 70
    • 28044467108 scopus 로고    scopus 로고
    • Zoledronic acid suppresses lung metastases and prolongs overall survival of osteosarcoma-bearing mice
    • Ory B., Heymann M.F., Kamijo A., et al. Zoledronic acid suppresses lung metastases and prolongs overall survival of osteosarcoma-bearing mice. Cancer 104 (2005) 2522-2529
    • (2005) Cancer , vol.104 , pp. 2522-2529
    • Ory, B.1    Heymann, M.F.2    Kamijo, A.3
  • 71
    • 10444274954 scopus 로고    scopus 로고
    • Efficacy of the third-generation bisphosphonate, zoledronic acid alone and combined with anti-cancer agents against small cell lung cancer cell lines
    • Matsumoto S., Kimura S., Segawa H., et al. Efficacy of the third-generation bisphosphonate, zoledronic acid alone and combined with anti-cancer agents against small cell lung cancer cell lines. Lung Cancer 47 (2005) 31-39
    • (2005) Lung Cancer , vol.47 , pp. 31-39
    • Matsumoto, S.1    Kimura, S.2    Segawa, H.3
  • 72
    • 79551559501 scopus 로고    scopus 로고
    • Presentation of Epstein Barr virus (EBV) epitopes by activated human γδ T cells induces peptide-specific cytolytic CD8+ T cell expansion [abstract]
    • [Abstract 1738]
    • Landmeier S., Altvater B., Pscherer S., et al. Presentation of Epstein Barr virus (EBV) epitopes by activated human γδ T cells induces peptide-specific cytolytic CD8+ T cell expansion [abstract]. Blood 108 (2006) [Abstract 1738]
    • (2006) Blood , vol.108
    • Landmeier, S.1    Altvater, B.2    Pscherer, S.3
  • 73
    • 33748080768 scopus 로고    scopus 로고
    • New insights into the role of T cells in the vicious cycle of bone metastases
    • Fournier P.G., Chirgwin J.M., and Guise T.A. New insights into the role of T cells in the vicious cycle of bone metastases. Curr Opin Rheumatol 18 (2006) 396-404
    • (2006) Curr Opin Rheumatol , vol.18 , pp. 396-404
    • Fournier, P.G.1    Chirgwin, J.M.2    Guise, T.A.3
  • 74
    • 71849099968 scopus 로고    scopus 로고
    • Multicenter, randomized, phase 2 study of zoledronic acid in combination with docetaxel and carboplatin in patients with unresectable stage IIIB or stage IV non-small cell lung cancer
    • [Epub ahead of print]
    • Pandya K.J., Gajra A., Warsi G.M., et al. Multicenter, randomized, phase 2 study of zoledronic acid in combination with docetaxel and carboplatin in patients with unresectable stage IIIB or stage IV non-small cell lung cancer. Lung Cancer (2009 Jun 1) [Epub ahead of print]
    • (2009) Lung Cancer
    • Pandya, K.J.1    Gajra, A.2    Warsi, G.M.3
  • 75
    • 60549097419 scopus 로고    scopus 로고
    • Endocrine therapy plus zoledronic acid in premenopausal breast cancer
    • Gnant M., Mlineritsch B., Schippinger W., et al. Endocrine therapy plus zoledronic acid in premenopausal breast cancer. N Engl J Med 360 (2009) 679-691
    • (2009) N Engl J Med , vol.360 , pp. 679-691
    • Gnant, M.1    Mlineritsch, B.2    Schippinger, W.3
  • 76
    • 49949115926 scopus 로고    scopus 로고
    • Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy
    • Gnant M., Mlineritsch B., Luschin-Ebengreuth G., et al. Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy. Lancet Oncol 9 (2008) 840-849
    • (2008) Lancet Oncol , vol.9 , pp. 840-849
    • Gnant, M.1    Mlineritsch, B.2    Luschin-Ebengreuth, G.3
  • 78
    • 71849119068 scopus 로고    scopus 로고
    • US National Institutes of Health, Z-PACT, Available at:, Accessed September 17, 2008
    • US National Institutes of Health. Non-small cell lung cancer study US75 (Z-PACT). Available at: http://www.clinicaltrials.gov/ct2/show/NCT00086268?term=zoledronic+acid+ AND+lung+cancer&rank=9. Accessed September 17, 2008.
    • Non-small cell lung cancer study


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.