Microsystem for isolation of fetal DNA from maternal plasma by preparative size separation

Clinical Chemistry

Volumn 55, Issue 12, 2009, Pages 2144-2152

  Hahn, Thomas ^a,b,d   Drese, Klaus S ^a   O'Sullivan, Ciara K ^b,c  

^a INSTITUT FÜR MIKROTECHNIK MAINZ GMBH   (Germany)

^b UNIVERSITAT ROVIRA I VIRGILI   (Spain)

^c INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^d DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA FRAGMENT; LEPTIN; POLYMER; TESTIS DETERMINING FACTOR;

ARTICLE; CELL FREE SYSTEM; CONTROLLED STUDY; DEVICE; DNA DETERMINATION; DNA ISOLATION; EXTRACTION; FEMALE; HUMAN; ISOTACHOPHORESIS; MATERNAL PLASMA; MICROANALYSIS; NON INVASIVE PROCEDURE; PREGNANCY; PRENATAL DIAGNOSIS; SRY GENE;

DNA; FEMALE; FETUS; HUMANS; MEMBRANES, ARTIFICIAL; MICROCHIP ANALYTICAL PROCEDURES; POLYMERASE CHAIN REACTION; POLYMETHYL METHACRYLATE; PREGNANCY; PRENATAL DIAGNOSIS;

EID: 71749110777     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2009.127480     Document Type: Article

References (39)

1. Lo YMD. Fetal DNA in maternal plasma/serum: the first 5 years. Pediatr Res 2003;53:16-17 (Pubitemid 36033978)
2. Lo YM, Corbetta N, Chamberlain PF, Rai V, Sargent IL, Redman CW, Wainscoat JS. Presence of fetal DNA in maternal plasma and serum. Lancet 1997;350:485-487 (Pubitemid 27343304)
3. Honda H, Miharu N, Ohashi Y, Samura O, Kinutani M, Hara T, Ohama K. Fetal gender determination in early pregnancy through qualitative and quantitative analysis of fetal DNA in maternal serum. Hum Genet 2002;110:75-79 (Pubitemid 36067421)
4. Amicucci P, Gennarelli M, Nevolli G, Dallapiccola B. Prenatal diagnosis of myotonic dystrophy using fetal DNA obtained from maternal plasma. Clin Chem 2000;46:301-302 (Pubitemid 30104263)
5. Chen CP, Chern SR, Wang W. Fetal DNA analyzed in plasma from a mother's three consecutive pregnancies to detect paternally inherited aneuploidy. Clin Chem 2001;47:937-939 (Pubitemid 32398047)
6. Costa JM, Benachi A, Gautier E. New strategy for prenatal diagnosis of X-linked disorders. N Engl J Med 2002;346:1502.
7. Finning KM, Martin PG, Soothill PW, Avent ND. Prediction of fetal D status from maternal plasma: introduction of a new noninvasive fetal RHD genotyping service. Transfusion 2002;42:1079-1085
8. Chiu RW, Lau TK, Cheung PT, Gong ZQ, Leung TN, Lo YM. Noninvasive prenatal exclusion of congenital adrenal hyperplasia by maternal plasma analysis: a feasibility study. Clin Chem 2002;48:778-780
9. Chiu RW, Lau TK, Leung TN, Chow KC, Chui DH, Lo YM. Prenatal exclusion of beta thalassaemia major by examination of maternal plasma. Lancet 2002;360:998-1000.
10. Lo YM, Hjelm NM, Fidler C, Sargent IL, Murphy MF, Chamberlain PF, et al. Prenatal diagnosis of fetal RhD status by molecular analysis of maternal plasma. N Engl J Med 1998;339:1734-1738 (Pubitemid 28555431)
11. Zhong XY, Gebhardt S, Hillermann R, Tofa KC, Holzgreve W, Hahn S. Parallel assessment of circulatory fetal DNA and corticotropin-releasing hormone mRNA in early-and late-onset pre-eclampsia. Clin Chem 2005;51:1730-1733 (Pubitemid 41233115)
12. Leung TN, Zhang J, Lau TK, Hjelm NM, Lo YM. Maternal plasma fetal DNA as a marker for preterm labour. Lancet 1998;352:1904-1905 (Pubitemid 28561255)
13. Lo YM, Lau TK, Zhang J, Leung TN, Chang AM, Hjelm NM, et al. Increased fetal DNA concentrations in the plasma of pregnant women carrying fetuses with trisomy 21. Clin Chem 1999;45:1747-1751 (Pubitemid 29477331)
14. Zhong XY, Holzgreve W, Li JC, Aydinli K, Hahn S. High levels of fetal erythroblasts and fetal extracellular DNA in the peripheral blood of a pregnant woman with idiopathic polyhydramnios: case report. Prenat Diagn 2000;20:838-841 (Pubitemid 30807835)
15. Sekizawa A, Jimbo M, Saito H, Iwasaki M, Sugito Y, Yukimoto Y, et al. Increased cell-free fetal DNA in plasma of two women with invasive placenta. Clin Chem 2002;48:353-354 (Pubitemid 34107273)
16. Lau TK, Lo KW, Chan LY, Leung TY, Lo YM. Cell-free fetal deoxyribonucleic acid in maternal circulation as a marker of fetal-maternal hemorrhage in patients undergoing external cephalic version near term. Am J Obstet Gynecol 2000;183:712-716
17. Lo YM, Tein MS, Lau TK, Haines CJ, Leung TN, Poon PM, et al. Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis. Am J Hum Genet 1998;62:768-775
18. Chan KC, Zhang J, Hui AB, Wong N, Lau TK, Leung TN, et al. Size distributions of maternal and fetal DNA in maternal plasma. Clin Chem 2004;50:88-92. (Pubitemid 38125703)
19. Li Y, Zimmermann B, Rusterholz C, Kang A, Holzgreve W, Hahn S. Size separation of circulatory DNA in maternal plasma permits ready detection of fetal DNA polymorphisms. Clin Chem 2004;50:1002-1011 (Pubitemid 38725787)
20. Tüdos AJ, Besselink GAJ, Schasfoort BM. Trends in miniaturized total analysis systems for point-of-care testing in clinical chemistry. Lab Chip 2001;1:83-95. (Pubitemid 37258313)
21. Srinivasan V, Pamula VK, Fair RB. An integrated digital microfluidic lab-on-a-chip for clinical diagnostics on human physiological fluids. Lab Chip 2004;4:310-315 (Pubitemid 39150230)
22. Verpoorte E. Microfluidic chips for clinical and forensic analysis. Electrophoresis 2002;23:677-712. (Pubitemid 34262874)
23. Hashimoto M, Chen PC, Mitchell MW, Nikitopoulos DE, Soper SA, Murphy MC. Rapid PCR in a continuous flow device. Lab Chip 2004;4:638-645 (Pubitemid 39657919)
24. Alarie JP, Jacobson SC, Ramsey JM. Electrophoretic injection bias in a microchip valving scheme. Electrophoresis 2001;22:312-317
25. Bianchi DW. Circulating fetal DNA: its origin and diagnostic potential - a review. Placenta 2004;25(Suppl A):S93-S101. (Pubitemid 38514964)
26. Lo YM, Patel P, Sampietro M, Gillmer MD, Fleming KA, Wainscoat JS. Detection of single-copy fetal DNA sequence from maternal blood. Lancet 1990;335:1463-1464 (Pubitemid 20186475)
27. Zimmermann B, El-Sheikhah A, Nicolaides K, Holzgreve W, Hahn S. Optimized real-time quantitative PCR measurement of male fetal DNA in maternal plasma. Clin Chem 2005;51:1598-1604 (Pubitemid 41233093)
28. Chiu RW, Lo YM. Noninvasive prenatal diagnosis by analysis of fetal DNA in maternal plasma. Methods Mol Biol 2006;336:101-109
29. van der Schoot CE, Tax GH, Rijnders RJ, de Haas M, Christiaens GC. Prenatal typing of Rh and Kell blood group system antigens: the edge of a watershed. Transfus Med Rev 2003;17:31-44.
30. Wainright A, Williams SJ, Ciambrone G, Xue Q, Wei J, Harris D. Sample pre-concentration by isotachophoresis in microfluidic devices. J Chromatogr A 2002;979:69-80. (Pubitemid 35341528)
31. Jung B, Bharadwaj R, Santiago JG. Thousandfold signal increase using field-amplified sample stacking for on-chip electrophoresis. Electrophoresis 2003;24:3476-3483 (Pubitemid 38089151)
32. Munson MS, Danger G, Shackman JG, Ross D. Temperature gradient focusing with field-amplified continuous sample injection for dual-stage analyte enrichment and separation. Anal Chem 2007;79:6201-6207 (Pubitemid 47282331)
33. Chen L, Prest JE, Fielden PR, Goddard NJ, Manz A, Day PJ. Miniaturised isotachophoresis analysis. Lab Chip 2006;6:474-487
34. Jung B, Bharadwaj R, Santiago JG. On-chip millionfold sample stacking using transient isotachophoresis. Anal Chem 2006;78:2319-2327
35. Wainright A, Nguyen UT, Bjornson T, Boone TD. Preconcentration and separation of double-stranded DNA fragments by electrophoresis in plastic microfluidic devices. Electrophoresis 2003;24:3784-3794 (Pubitemid 38089184)
36. Dai J, Ito T, Sun L, Crooks RM. Electrokinetic trapping and concentration enrichment of DNA in a microfluidic channel. J Am Chem Soc 2003;125:13026-13027 (Pubitemid 37305590)
37. Park SR, Swerdlow H. Concentration of DNA in a flowing stream for high-sensitivity capillary electrophoresis. Anal Chem 2003;75:4467-4474 (Pubitemid 37086666)
38. Hahn T, O'Sullivan CK, Drese KS. Microsystem for field-amplified electrokinetic trapping pre-concentration of DNA at poly(ethylene terephthalate) membranes. Anal Chem 2009;81:2904-2911
39. Abramoff MD, Magelhaes PJ, Ram SJ. Image processing with ImageJ. Biophotonics Int 2004;11:36-42.