Isomer-specific effects of conjugated linoleic acid on gene expression in RAW 264.7

Journal of Nutritional Biochemistry

Volumn 20, Issue 11, 2009, Pages

  Lee, Yunkyoung ^a   Thompson, Jerry T ^b   de Lera, Angel R ^c   Vanden Heuvel, John P ^a,b  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF VIGO   (Spain)

Author keywords

Conjugated linoleic acid; Gene expression; Inflammation; Macrophage; Peroxisome proliferator activated receptor

Indexed keywords

CONJUGATED LINOLEIC ACID; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETINOID X RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE TARGETING; INFLAMMATION; ISOMER; MICROARRAY ANALYSIS; MOUSE; NONHUMAN;

ANIMALIA;

EID: 71749109070     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2008.07.013     Document Type: Article

References (61)

1. Pariza M.W., and Ha Y.L. Conjugated dienoic derivatives of linoleic acid: a new class of anticarcinogens. Med Oncol Tumor Pharmacother 7 (1990) 169-171
2. Lin H., Boylston T.D., Chang M.J., Luedecke L.O., and Shultz T.D. Survey of the conjugated linoleic acid contents of dairy products. J Dairy Sci 78 (1995) 2358-2365
3. Ritzenthaler K.L., McGuire M.K., Falen R., Shultz T.D., Dasgupta N., and McGuire M.A. Estimation of conjugated linoleic acid intake by written dietary assessment methodologies underestimates actual intake evaluated by food duplicate methodology. J Nutr 131 (2001) 1548-1554
4. Yurawecz M.P., Mossoba M.M., Kramer J.K.G., Pariza M.W., and Nelson G.J. Advances in Conjugated Linoleic Acid Research Vol. 1 (1999), AOCS Press, Champaign, IL 378-396
5. Wahle K.W., Heys S.D., and Rotondo D. Conjugated linoleic acids: are they beneficial or detrimental to health?. Prog Lipid Res 43 (2004) 553-587
6. Munday J.S., Thompson K.G., and James K.A. Dietary conjugated linoleic acids promote fatty streak formation in the C57BL/6 mouse atherosclerosis model. Br J Nutr 81 (1999) 251-255
7. Toomey S., Harhen B., Roche H.M., Fitzgerald D., and Belton O. Profound resolution of early atherosclerosis with conjugated linoleic acid. Atherosclerosis 187 (2006) 40-49
8. Ma D.W., Field C.J., and Clandinin M.T. An enriched mixture of trans-10,cis-12-CLA inhibits linoleic acid metabolism and PGE2 synthesis in MDA-MB-231 cells. Nutr Cancer 44 (2002) 203-212
9. Ogborn M.R., Nitschmann E., Bankovic-Calic N., Weiler H.A., Fitzpatrick-Wong S., and Aukema H.M. Dietary conjugated linoleic acid reduces PGE2 release and interstitial injury in rat polycystic kidney disease. Kidney Int 64 (2003) 1214-1221
10. Nakanishi T., Koutoku T., Kawahara S., Murai A., and Furuse M. Dietary conjugated linoleic acid reduces cerebral prostaglandin E(2) in mice. Neurosci Lett 341 (2003) 135-138
11. Houseknecht K.L., Vanden Heuvel J.P., Moya-Camarena S.Y., Portocarrero C.P., Peck L.W., Nickel K.P., et al. Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat. Biochem Biophys Res Commun 244 (1998) 678-682
12. Yu Y., Correll P.H., and Vanden Heuvel J.P. Conjugated linoleic acid decreases production of pro-inflammatory products in macrophages: evidence for a PPAR gamma-dependent mechanism. Biochim Biophys Acta 1581 (2002) 89-99
13. Akahoshi A., Goto Y., Murao K., Miyazaki T., Yamasaki M., Nonaka M., et al. Conjugated linoleic acid reduces body fats and cytokine levels of mice. Biosci Biotechnol Biochem 66 (2002) 916-920
14. Song H.J., Sneddon A.A., Heys S.D., and Wahle K.W. Induction of apoptosis and inhibition of NF-kappaB activation in human prostate cancer cells by the cis-9, trans-11 but not the trans-10, cis-12 isomer of conjugated linoleic acid. Prostate 66 (2006) 839-846
15. Cheng W.L., Lii C.K., Chen H.W., Lin T.H., and Liu K.L. Contribution of conjugated linoleic acid to the suppression of inflammatory responses through the regulation of the NF-kappaB pathway. J Agric Food Chem 52 (2004) 71-78
16. Yang M., and Cook M.E. Dietary conjugated linoleic acid decreased cachexia, macrophage tumor necrosis factor-alpha production, and modifies splenocyte cytokines production. Exp Biol Med (Maywood) 228 (2003) 51-58
17. Song H.J., Grant I., Rotondo D., Mohede I., Sattar N., Heys S.D., et al. Effect of CLA supplementation on immune function in young healthy volunteers. Eur J Clin Nutr 59 (2005) 508-517
18. Bhattacharya A., Banu J., Rahman M., Causey J., and Fernandes G. Biological effects of conjugated linoleic acids in health and disease. J Nutr Biochem (2006)
19. Moya-Camarena S.Y., Vanden Heuvel J.P., Blanchard S.G., Leesnitzer L.A., and Belury M.A. Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARalpha. J Lipid Res 40 (1999) 1426-1433
20. Ringseis R., Muller A., Herter C., Gahler S., Steinhart H., and Eder K. CLA isomers inhibit TNFalpha-induced eicosanoid release from human vascular smooth muscle cells via a PPARgamma ligand-like action. Biochim Biophys Acta 1760 (2006) 290-300
21. Pogenberg V., Guichou J.F., Vivat-Hannah V., Kammerer S., Perez E., Germain P., et al. Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies. J Biol Chem 280 (2005) 1625-1633
22. Coleman J.D., Prabhu K.S., Thompson J.T., Reddy P.S., Peters J.M., Peterson B.R., et al. The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta). Free Radic Biol Med 42 (2007) 1155-1164
23. Vanden Heuvel J.P., Thompson J.T., Frame S.R., and Gillies P.J. Differential activation of nuclear receptors by perfluorinated fatty acid analogs and natural fatty acids: a comparison of human, mouse, and rat peroxisome proliferator-activated receptor-alpha, -beta, and -gamma, liver X receptor-beta, and retinoid X receptor-alpha. Toxicol Sci 92 (2006) 476-489
24. Chang C., Norris J.D., Gron H., Paige L.A., Hamilton P.T., Kenan D.J., et al. Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta. Mol Cell Biol 19 (1999) 8226-8239
25. Tien E.S., Gray J.P., Peters J.M., and Vanden Heuvel J.P. Comprehensive gene expression analysis of peroxisome proliferator-treated immortalized hepatocytes: identification of peroxisome proliferator-activated receptor alpha-dependent growth regulatory genes. Cancer Res 63 (2003) 5767-5780
26. Soumian S., Albrecht C., Davies A.H., and Gibbs R.G. ABCA1 and atherosclerosis. Vasc Med 10 (2005) 109-119
27. Li A.C., Binder C.J., Gutierrez A., Brown K.K., Plotkin C.R., Pattison J.W., et al. Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma. J Clin Invest 114 (2004) 1564-1576
28. Miles R.R., Sluka J.P., Halladay D.L., Santerre R.F., Hale L.V., Bloem L., et al. ADAMTS-1: A cellular disintegrin and metalloprotease with thrombospondin motifs is a target for parathyroid hormone in bone. Endocrinology 141 (2000) 4533-4542
29. Shindo T., Kurihara H., Kuno K., Yokoyama H., Wada T., Kurihara Y., et al. ADAMTS-1: a metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function. J Clin Invest 105 (2000) 1345-1352
30. Stangl G.I. High dietary levels of a conjugated linoleic acid mixture alter hepatic glycerophospholipid class profile and cholesterol-carrying serum lipoproteins of rats. J Nutr Biochem 11 (2000) 184-191
31. O'Shea M., Devery R., Lawless F., Murphy J., and Stanton C. Milk fat conjugated linoleic acid (CLA) inhibits growth of human mammary MCF-7 cancer cells. Anticancer Res 20 (2000) 3591-3601
32. Adachi H., and Tsujimoto M. Endothelial scavenger receptors. Prog Lipid Res 45 (2006) 379-404
33. Jiang C., Ting A.T., and Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 391 (1998) 82-86
34. Kuliczkowska-Plaksej J., Bednarek-Tupikowska G., Plaksej R., and Filus A. The influence of diabetes mellitus and insulin resistance on receptor CD36 expression. Part II. The role of receptor CD36 in the pathomechanism of diabetes complications. Postepy Hig Med Dosw (Online) 60 (2006) 152-162
35. DeGrazia M.J., Thompson J., Heuvel J.P., and Peterson B.R. Synthesis of a high-affinity fluorescent PPARgamma ligand for high-throughput fluorescence polarization assays. Bioorg Med Chem 11 (2003) 4325-4332
36. Zavrides H.N., Zizi-Sermpetzoglou A., Panousopoulos D., Athanasas G., Elemenoglou I., and Peros G. Prognostic evaluation of CD44 expression in correlation with bcl-2 and p53 in colorectal cancer. Folia Histochem Cytobiol 43 (2005) 31-36
37. Hwang H.C., and Clurman B.E. Cyclin E in normal and neoplastic cell cycles. Oncogene 24 (2005) 2776-2786
38. Kemp M.Q., Jeffy B.D., and Romagnolo D.F. Conjugated linoleic acid inhibits cell proliferation through a p53-dependent mechanism: effects on the expression of G1-restriction points in breast and colon cancer cells. J Nutr 133 (2003) 3670-3677
39. Cho H.J., Kim E.J., Lim S.S., Kim M.K., Sung M.K., Kim J.S., et al. Trans-10,cis-12, not cis-9,trans-11, conjugated linoleic acid inhibits G1-S progression in HT-29 human colon cancer cells. J Nutr 136 (2006) 893-898
40. Hogg D., Guidos C., Bailey D., Amendola A., Groves T., Davidson J., et al. Cell cycle dependent regulation of the protein kinase TTK. Oncogene 9 (1994) 89-96
41. Kulski J.K., Kenworthy W., Bellgard M., Taplin R., Okamoto K., Oka A., et al. Gene expression profiling of Japanese psoriatic skin reveals an increased activity in molecular stress and immune response signals. J Mol Med 83 (2005) 964-975
42. Vanaja D.K., Ballman K.V., Morlan B.W., Cheville J.C., Neumann R.M., Lieber M.M., et al. PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer. Clin Cancer Res 12 (2006) 1128-1136
43. van Harmelen V., Ryden M., Sjolin E., and Hoffstedt J. A role of lipin in human obesity and insulin resistance: relation to adipocyte glucose transport and GLUT4 expression. J Lipid Res 48 (2007) 201-206
44. Brachat A., Pierrat B., Xynos A., Brecht K., Simonen M., Brungger A., et al. A microarray-based, integrated approach to identify novel regulators of cancer drug response and apoptosis. Oncogene 21 (2002) 8361-8371
45. Denecke B., Meyerdierks A., and Bottger E.C. RGS1 is expressed in monocytes and acts as a GTPase-activating protein for G-protein-coupled chemoattractant receptors. J Biol Chem 274 (1999) 26860-26868
46. Wheeler A.P., and Ridley A.J. Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility. Exp Cell Res 301 (2004) 43-49
47. Kelley D.S., Warren J.M., Simon V.A., Bartolini G., Mackey B.E., and Erickson K.L. Similar effects of c9,t11-CLA and t10,c12-CLA on immune cell functions in mice. Lipids 37 (2002) 725-728
48. Yamasaki M., Chujo H., Hirao A., Koyanagi N., Okamoto T., Tojo N., et al. Immunoglobulin and cytokine production from spleen lymphocytes is modulated in C57BL/6J mice by dietary cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid. J Nutr 133 (2003) 784-788
49. Arend W.P. Interleukin 1 receptor antagonist. A new member of the interleukin 1 family. J Clin Invest 88 (1991) 1445-1451
50. Seckinger P., Williamson K., Balavoine J.F., Mach B., Mazzei G., Shaw A., et al. A urine inhibitor of interleukin 1 activity affects both interleukin 1 alpha and 1 beta but not tumor necrosis factor alpha. J Immunol 139 (1987) 1541-1545
51. Arend W.P., Welgus H.G., Thompson R.C., and Eisenberg S.P. Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist. J Clin Invest 85 (1990) 1694-1697
52. Arend W.P., Malyak M., Guthridge C.J., and Gabay C. Interleukin-1 receptor antagonist: role in biology. Annu Rev Immunol 16 (1998) 27-55
53. Arend W.P. The balance between IL-1 and IL-1Ra in disease. Cytokine Growth Factor Rev 13 (2002) 323-340
54. Ishida Y., Kondo T., Kimura A., Matsushima K., and Mukaida N. Absence of IL-1 receptor antagonist impaired wound healing along with aberrant NF-kappaB activation and a reciprocal suppression of TGF-beta signal pathway. J Immunol 176 (2006) 5598-5606
55. Martin J.C., and Valeille K. Conjugated linoleic acids: all the same or to everyone its own function?. Reprod Nutr Dev 42 (2002) 525-536
56. Beppu F., Hosokawa M., Tanaka L., Kohno H., Tanaka T., and Miyashita K. Potent inhibitory effect of trans9, trans11 isomer of conjugated linoleic acid on the growth of human colon cancer cells. J Nutr Biochem 17 (2006) 830-836
57. Ecker J., Langmann T., Moehle C., and Schmitz G. Isomer specific effects of Conjugated Linoleic Acid on macrophage ABCG1 transcription by a SREBP-1c dependent mechanism. Biochem Biophys Res Commun 352 (2007) 805-811
58. Tronstad K.J., Gjertsen B.T., Krakstad C., Berge K., Brustugun O.T., Doskeland S.O., et al. Mitochondrial-targeted fatty acid analog induces apoptosis with selective loss of mitochondrial glutathione in promyelocytic leukemia cells. Chem Biol 10 (2003) 609-618
59. Berge K., Tronstad K.J., Bohov P., Madsen L., and Berge R.K. Impact of mitochondrial beta-oxidation in fatty acid-mediated inhibition of glioma cell proliferation. J Lipid Res 44 (2003) 118-127
60. Madsen L., Guerre-Millo M., Flindt E.N., Berge K., Tronstad K.J., Bergene E., et al. Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance. J Lipid Res 43 (2002) 742-750
61. Westergaard M., Henningsen J., Svendsen M.L., Johansen C., Jensen U.B., Schroder H.D., et al. Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid. J Invest Dermatol 116 (2001) 702-712