Circulating triglycerides after a high-fat meal: Predictor of increased caloric intake, orexigenic peptide expression, and dietary obesity

Brain Research

Volumn 1298, Issue , 2009, Pages 111-122

  Karatayev, O ^a   Gaysinskaya, V ^a   Chang, G Q ^a   Leibowitz, S F ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Body fat; Hypothalamus; Overeating; Triglycerides

Indexed keywords

ENKEPHALIN; MELANIN CONCENTRATING HORMONE; OREXIN; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY FAT; BODY WEIGHT; CALORIC INTAKE; CONTROLLED STUDY; FEEDING BEHAVIOR; IMMUNOHISTOCHEMISTRY; LIPID DIET; MALE; NONHUMAN; OBESITY; OVERNUTRITION; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN;

ADIPOSE TISSUE; AGOUTI-RELATED PROTEIN; ANIMALS; BODY WEIGHT; DIETARY FATS; EATING; ENERGY INTAKE; FEEDING BEHAVIOR; FLUORESCENT ANTIBODY TECHNIQUE; HYPOTHALAMIC HORMONES; HYPOTHALAMUS; IMAGE PROCESSING, COMPUTER-ASSISTED; IN SITU HYBRIDIZATION; INSULIN; LEPTIN; MALE; MELANINS; MICROSCOPY, FLUORESCENCE; NEUROPEPTIDES; OBESITY; PITUITARY HORMONES; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRIGLYCERIDES;

RATTUS;

EID: 71749102385     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.08.001     Document Type: Article

References (52)

1. Alavian S.M., Motlagh M.E., Ardalan G., Motaghian M., Davarpanah A.H., and Kelishadi R. Hypertriglyceridemic waist phenotype and associated lifestyle factors in a national population of youths: CASPIAN Study. J. Trop. Pediatr. 54 (2008) 169-177
2. Banks W.A., Coon A.B., Robinson S.M., Moinuddin A., Shultz J.M., Nakaoke R., and Morley J.E. Triglycerides induce leptin resistance at the blood-brain barrier. Diabetes 53 (2004) 1253-1260
3. Chang G.Q., Karatayev O., Davydova Z., and Leibowitz S.F. Circulating triglycerides impact on orexigenic peptides and neuronal activity in hypothalamus. Endocrinology 145 (2004) 3904-3912
4. Chang G.Q., Karatayev O., Ahsan R., Gaysinskaya V., Marwil Z., and Leibowitz S.F. Dietary fat stimulates endogenous enkephalin and dynorphin in the paraventricular nucleus: role of circulating triglycerides. Am. J. Physiol. Endocrinol. Metab. 292 (2007) E561-570
5. Chang G.Q., Gaysinskaya V., Karatayev O., and Leibowitz S.F. Maternal high-fat diet and fetal programming: increased proliferation of hypothalamic peptide-producing neurons that increase risk for overeating and obesity. J. Neurosci. 28 (2008) 12107-12119
6. Chen H.C., Stone S.J., Zhou P., Buhman K.K., and Farese Jr. R.V. Dissociation of obesity and impaired glucose disposal in mice overexpressing acyl coenzyme a:diacylglycerol acyltransferase 1 in white adipose tissue. Diabetes 51 (2002) 3189-3195
7. Chen H.C., Smith S.J., Ladha Z., Jensen D.R., Ferreira L.D., Pulawa L.K., McGuire J.G., Pitas R.E., Eckel R.H., and Farese Jr. R.V. Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1. J. Clin. Invest. 109 (2002) 1049-1055
8. Clegg D.J., Air E.L., Woods S.C., and Seeley R.J. Eating elicited by orexin-a, but not melanin-concentrating hormone, is opioid mediated. Endocrinology 143 (2002) 2995-3000
9. Commerford S.R., Pagliassotti M.J., Melby C.L., Wei Y., Gayles E.C., and Hill J.O. Fat oxidation, lipolysis, and free fatty acid cycling in obesity-prone and obesity-resistant rats. Am. J. Physiol. Endocrinol. Metab. 279 (2000) E875-885
10. de Castro J.M. Dietary energy density is associated with increased intake in free-living humans. J. Nutr. 134 (2004) 335-341
11. Dourmashkin J.T., Chang G.Q., Hill J.O., Gayles E.C., Fried S.K., and Leibowitz S.F. Model for predicting and phenotyping at normal weight the long-term propensity for obesity in Sprague-Dawley rats. Physiol. Behav. 87 (2006) 666-678
12. Esmaillzadeh A., Mirmiran P., and Azizi F. Clustering of metabolic abnormalities in adolescents with the hypertriglyceridemic waist phenotype. Am. J. Clin. Nutr. 83 (2006) 36-46 quiz 183-184
13. Gaysinskaya V.A., Karatayev O., Chang G.Q., and Leibowitz S.F. Increased caloric intake after a high-fat preload: relation to circulating triglycerides and orexigenic peptides. Physiol. Behav. 91 (2007) 142-153
14. Geliebter A.A. Effects of equicaloric loads of protein, fat, and carbohydrate on food intake in the rat and man. Physiol. Behav. 22 (1979) 267-273
15. Harris G.C., Wimmer M., and Aston-Jones G. A role for lateral hypothalamic orexin neurons in reward seeking. Nature 437 (2005) 556-559
16. Jackman M.R., Kramer R.E., MacLean P.S., and Bessesen D.H. Trafficking of dietary fat in obesity-prone and obesity-resistant rats. Am. J. Physiol. Endocrinol. Metab. 291 (2006) E1083-E1091
17. Ji H., and Friedman M.I. Fasting plasma triglyceride levels and fat oxidation predict dietary obesity in rats. Physiol. Behav. 78 (2003) 767-772
18. Ji H., and Friedman M.I. Reduced hepatocyte fatty acid oxidation in outbred rats prescreened for susceptibility to diet-induced obesity. Int. J. Obes. (Lond). 32 (2008) 1331-1334
19. Ji H., Outterbridge L.V., and Friedman M.I. Phenotype-based treatment of dietary obesity: differential effects of fenofibrate in obesity-prone and obesity-resistant rats. Metabolism 54 (2005) 421-429
20. Kennedy A.R., Pissios P., Otu H., Xue B., Asakura K., Furukawa N., Marino F.E., Liu F.F., Kahn B.B., Libermann T.A., Maratos-Flier E., and Roberson R. A high-fat, ketogenic diet induces a unique metabolic state in mice. Am. J. Physiol. Endocrinol. Metab. 292 (2007) E1724-1739
21. Leibowitz S.F. Regulation and effects of hypothalamic galanin: relation to dietary fat, alcohol ingestion, circulating lipids and energy homeostasis. Neuropeptides 39 (2005) 327-332
22. Leibowitz S.F., Dourmashkin J.T., Chang G.Q., Hill J.O., Gayles E.C., Fried S.K., and Wang J. Acute high-fat diet paradigms link galanin to triglycerides and their transport and metabolism in muscle. Brain Res. 1008 (2004) 168-178
23. Levine A.S., and Billington C.J. Opioids as agents of reward-related feeding: a consideration of the evidence. Physiol. Behav. 82 (2004) 57-61
24. Lin L., York D.A., and Bray G.A. Comparison of Osborne-Mendel and S5B/PL strains of rat: central effects of galanin, NPY, beta-casomorphin and CRH on intake of high-fat and low-fat diets. Obes. Res. 4 (1996) 117-124
25. Lo C.M., Ma L., Zhang D.M., Lee R., Qin A., Liu M., Woods S.C., Sakai R.R., Raybould H.E., and Tso P. Mechanism of the induction of brain c-Fos-positive neurons by lipid absorption. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292 (2007) R268-273
26. Lucas F., and Sclafani A. Differential reinforcing and satiating effects of intragastric fat and carbohydrate infusions in rats. Physiol. Behav. 66 (1999) 381-388
27. Lucas L.R., Pompei P., Ono J., and McEwen B.S. Effects of adrenal steroids on basal ganglia neuropeptide mRNA and tyrosine hydroxylase radioimmunoreactive levels in the adrenalectomized rat. J. Neurochem. 71 (1998) 833-843
28. Monnikes H., Lauer G., Bauer C., Tebbe J., Zittel T.T., and Arnold R. Pathways of Fos expression in locus ceruleus, dorsal vagal complex, PVN in response to intestinal lipide. Am. J. Physiol. 273 (1997) R2059-R2071
29. Onat A., Sari I., Yazici M., Can G., Hergenc G., and Avci G.S. Plasma triglycerides, an independent predictor of cardiovascular disease in men: a prospective study based on a population with prevalent metabolic syndrome. Int. J. Cardiol. 108 (2006) 89-95
30. Prentice A.M. Manipulation of dietary fat and energy density and subsequent effects on substrate flux and food intake. Am. J. Clin. Nutr. 67 (1998) 535S-541S
31. Ramirez I., and Friedman M.I. Dietary hyperphagia in rats: role of fat, carbohydrate, and energy content. Physiol. Behav. 47 (1990) 1157-1163
32. Reagan L.P., Rosell D.R., Wood G.E., Spedding M., Munoz C., Rothstein J., and McEwen B.S. Chronic restraint stress up-regulates GLT-1 mRNA and protein expression in the rat hippocampus: reversal by tianeptine. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 2179-2184
33. Reis E.C., Kip K.E., Marroquin O.C., Kiesau M., Hipps Jr. L., Peters R.E., and Reis S.E. Screening children to identify families at increased risk for cardiovascular disease. Pediatrics 118 (2006) e1789-e1797
34. Robinson T.M., Gray R.W., Yeomans M.R., and French S.J. Test-meal palatability alters the effects of intragastric fat but not carbohydrate preloads on intake and rated appetite in healthy volunteers. Physiol. Behav. 84 (2005) 193-203
35. Rolls B.J. Carbohydrates, fats, and satiety. Am. J. Clin. Nutr. 61 (1995) 960S-967S
36. Rolls B.J., and Shide D.J. The influence of dietary fat on food intake and body weight. Nutr. Rev. 50 (1992) 283-290
37. Sclafani A. Dietary-induced overeating. Ann. N. Y. Acad. Sci. 575 (1989) 281-289
38. Shor-Posner G., Brennan G., Ian C., Jasaitis R., Madhu K., and Leibowitz S.F. Meal patterns of macronutrient intake in rats with particular dietary preferences. Am. J. Physiol. 266 (1994) R1395-R1402
39. Synowski S.J., Smart A.B., and Warwick Z.S. Meal size of high-fat food is reliably greater than high-carbohydrate food across externally-evoked single-meal tests and long-term spontaneous feeding in rat. Appetite 45 (2005) 191-194
40. Urayama A., and Banks W.A. Starvation and triglycerides reverse the obesity-induced impairment of insulin transport at the blood-brain barrier. Endocrinology 149 (2008) 3592-3597
41. Warwick Z.S. Probing the causes of high-fat diet hyperphagia: a mechanistic and behavioral dissection. Neurosci. Biobehav. Rev. 20 (1996) 155-161
42. Warwick Z.S., and Weingarten H.P. Dynamics of intake suppression after a preload: role of calories, volume, and macronutrients. Am. J. Physiol. 266 (1994) R1314-R1318
43. Warwick Z.S., and Weingarten H.P. Determinants of high-fat diet hyperphagia: experimental dissection of orosensory and postingestive effects. Am. J. Physiol. 269 (1995) R30-37
44. Warwick Z.S., McGuire C.M., Bowen K.J., and Synowski S.J. Behavioral components of high-fat diet hyperphagia: meal size and postprandial satiety. Am. J. Physiol. Regul. Integr. Comp. Physiol. 278 (2000) R196-R200
45. Warwick Z.S., Synowski S.J., and Bell K.R. Dietary fat content affects energy intake and weight gain independent of diet caloric density in rats. Physiol. Behav. 77 (2002) 85-90
46. Warwick Z.S., Synowski S.J., Rice K.D., and Smart A.B. Independent effects of diet palatability and fat content on bout size and daily intake in rats. Physiol. Behav. 80 (2003) 253-258
47. Welch C.C., Kim E.M., Grace M.K., Billington C.J., and Levine A.S. Palatability-induced hyperphagia increases hypothalamic Dynorphin peptide and mRNA levels. Brain Res. 721 (1996) 126-131
48. Wetzler S., Jean-Joseph G., Even P., Tome D., and Larue-Achagiotis C. Acute third ventricular administration of leptin decreases protein and fat in self-selecting rats. Behav. Brain. Res. 159 (2005) 119-125
49. Woods S.C. Signals that influence food intake and body weight. Physiol. Behav. 86 (2005) 709-716
50. Woods S.C., and Seeley R.J. Adiposity signals and the control of energy homeostasis. Nutrition 16 (2000) 894-902
51. Wortley K.E., Chang G.Q., Davydova Z., and Leibowitz S.F. Peptides that regulate food intake: orexin gene expression is increased during states of hypertriglyceridemia. Am. J. Physiol. Regul. Integr. Comp. Physiol. 284 (2003) R1454-R1465
52. Yun R., Dourmashkin J.T., Hill J.O., Gayles E.C., Fried S.K., and Leibowitz S.F. PVN galanin increases fat storage and promotes obesity by causing muscle to utilize carbohydrate more than fat. Peptides 26 (2005) 2265-2273