Analysis of POPs in human samples reveal a contribution of brominated dioxin of up to 15% of the total dioxin TEQ

Chemosphere

Volumn 78, Issue 2, 2010, Pages 113-120

  Ericson Jogsten, Ingrid ^a   Hagberg, Jessika ^a   Lindström, Gunilla ^a   Bavel, Bert van ^a  

^a ÖREBRO UNIVERSITY   (Sweden)

Author keywords

Human samples; PBDD; PBDE; PBDF; PFC; TEQ

Indexed keywords

GAS CHROMATOGRAPHY; MASS SPECTROMETRY; ORGANIC CHEMICALS; POLYCHLORINATED BIPHENYLS; TISSUE; TISSUE ENGINEERING;

HIGH-RESOLUTION GAS CHROMATOGRAPHY/HIGH-RESOLUTION MASS SPECTROMETRIES; PBDD; PBDE; PBDF; POLYBROMINATED DIBENZO-P-DIOXINS; POLYBROMINATED DIPHENYL ETHER (PBDES); POLYCHLORINATED BIPHENYL (PCBS); POLYCHLORINATED DIBENZO-P-DIOXINS AND DIBENZOFURANS;

ORGANIC POLLUTANTS;

2,3,4,7,8 PENTABROMODIBENZOFURAN; 2,3,7,8 TETRABROMODIBENZOFURAN; 2,7 DIBROMODIBENZOFURAN; 2,8 DIBROMODIBENZOFURAN; BROMINE; DIBENZOFURAN; DIBENZOFURAN DERIVATIVE; DIOXIN; LIPID; PERFLUORO COMPOUND; POLYBROMINATED DIBENZODIOXIN; POLYBROMINATED DIPHENYL ETHER; POLYCHLORINATED BIPHENYL; POLYCHLORINATED DIBENZODIOXIN; UNCLASSIFIED DRUG;

DIOXIN; GAS CHROMATOGRAPHY; LIPID; MASS SPECTROMETRY; PBDE; POLLUTION EFFECT; TOXICITY;

ADIPOSE TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; ENVIRONMENTAL MONITORING; GAS CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; MASS SPECTROMETRY; ORGANIC POLLUTION; POLLUTANT; POLLUTION MONITORING; QUALITY CONTROL; SWEDEN;

EID: 71649102079     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2009.10.012     Document Type: Article

References (42)

1. Ashizuka Y., Nakagawa R., Hori T., Yasutake D., Tobiishi K., and Sasaki K. Determination of brominated flame retardants and brominated dioxins in fish collected from three regions of Japan. Mol. Nutr. Food Res. 52 (2008) 273-283
2. Behnisch P.A., Hosoe K., and Sakai S.-I. Brominated dioxin-like compounds: in vitro assessment in comparison to classical dioxin-like compounds and other polyaromatic compounds. Environ. Int. 29 (2003) 861-877
3. Birnbaum L.S., Staskal D.F., and Diliberto J.J. Health effects of polybrominated dibenzo-p-dioxins (PBDDs) and dibenzofurans (PBDFs). Environ. Int. 29 (2003) 855-860
4. Buser H.R. Polybrominated dibenzofurans and dibenzo-para-dioxins - Thermal-reaction products of polybrominated diphenyl ether flame retardants. Environ. Sci. Technol. 20 (1986) 404-408
5. Choi J.W., Fujimaki S., Kitamura K., Hashimoto S., Ito H., Suzuki N., Sakai S., and Morita M. Polybrominated dibenzo-p-dioxins, dibenzofurans, and diphenyl ethers in Japanese human adipose tissue. Environ. Sci. Technol. 37 (2003) 817-821
6. Choi J.W., Onodera J., Kitamura K., Hashimoto S., Ito H., Suzuki N., Sakai S., and Morita M. Modified clean-up for PBDD, PBDF and PBDE with an active carbon column - Its application to sediments. Chemosphere 53 (2003) 637-643
7. de Wit C.A. An overview of brominated flame retardants in the environment. Chemosphere 46 (2002) 583-624
8. Ebert J., and Bahadir M. Formation of PBDD/F from flame-retarded plastic materials under thermal stress. Environ. Int. 29 (2003) 711-716
9. Ericson Jogsten I., Perelló G., Llebaria X., Bigas E., Martí-Cid R., Kärrman A., and Domingo J.L. Exposure to perfluorinated compounds in Catalonia, Spain, through consumption of various raw and cooked foodstuffs, including packaged food. Food Chem. Toxicol. 47 (2009) 1577-1583
10. Fangstrom B., Athanassiadis I., Odsjo T., Norén K., and Bergman A. Temporal trends of polybrominated diphenyl ethers and hexabromocyclododecane in milk from Stockholm mothers, 1980-2004. Mol. Nutr. Food Res. 52 (2008) 187-193
11. Fernandes A., Dicks P., Mortimer D., Gem M., Smith F., Ield M.D., White S., and Rose M. Brominated and chlorinated dioxins, PCBs and brominated flame retardants in Scottish shellfish: methodology, occurrence and human dietary exposure. Mol. Nutr. Food Res. 52 (2008) 238-249
12. Hagberg J. Analysis of brominated dioxins and furans by high resolution gas chromatography/high resolution mass spectrometry. J. Chromatogr. A 1216 (2009) 376-384
13. Hagberg J., Olsman H., van Bavel B., Engwall M., and Lindström G. Chemical and toxicological characterisation of PBDFs from photolytic decomposition of decaBDE in toluene. Environ. Int. 32 (2006) 851-857
14. Hagberg J., Ábalos M., Abad E., and van Bavel B. Applying pressurized liquid extraction (PLE) and automated cleanup (power prep) for PBDD/F analysis in soil. Organohalogen Compd. 70 (2008) 764-767
15. Hanari N., Kannan K., Miyake Y., Okazawa T., Kodavanti P.R.S., Aldous K.M., and Yamashita N. Occurrence of polybrominated biphenyls, polybrominated dibenzo-p-dioxins, and polybrominated dibenzofurans as impurities in commercial polybrominated diphenyl ether mixtures. Environ. Sci. Technol. 40 (2006) 4400-4405
16. Hayakawa K., Takatsuki H., Watanabe I., and Sakai S.-i. Polybrominated diphenyl ethers (PBDEs), polybrominated dibenzo-p-dioxins/dibenzofurans (PBDD/Fs) and monobromo-polychlorinated dibenzo-p-dioxins/dibenzofurans (MoBPXDD/Fs) in the atmosphere and bulk deposition in Kyoto, Japan. Chemosphere 57 (2004) 343-356
17. Kajiwara N., Noma Y., and Takigami H. Photolysis studies of technical decabromodiphenyl ether (DecaBDE) and ethane (DeBDethane) in plastics under natural sunlight. Environ. Sci. Technol. 42 (2008) 4404-4409
18. Karrman A., Ericson I., and Van Bavel B. Exposure of perfluorinated chemicals through lactation: levels of matched human milk and serum and a temporal trend, 1996-2004, in Sweden. Environ. Health Perspect. 115 (2007) 226-231
19. Kotz, A., 2006. Bestimmung von bromierten und gemischt bromiert-chlorierten unweltkontaminanten in biologischen matrizes mit HRGC-HRMS. PhD Thesis, Faculty of Science, University of Basel.
20. Kotz A., Malisch R., Kypke K., and Oehme M. PBDE, PBDD/F and mixed chlorinated-brominated PXDD/F in pooled human milk samples from different countries. Organohalogen Compd. 67 (2005) 1624-1627
21. Law R.J., Allchin C.R., de Boer J., Covaci A., Herzke D., Lepom P., Morris S., Tronczynski J., and de Wit C.A. Levels and trends of brominated flame retardants in the European environment. Chemosphere 64 (2006) 187-208
22. Li H., Yu L., Sheng G., Fu J., and Peng P.a. Severe PCDD/F and PBDD/F pollution in air around an electronic waste dismantling area in China. Environ. Sci. Technol. 41 (2007) 5641-5646
23. Li H., Feng J., Sheng G., Lü S., Fu J., Peng P.a., and Man R. The PCDD/F and PBDD/F pollution in the ambient atmosphere of Shanghai, China. Chemosphere 70 (2008) 576-583
24. Mandalakis M., Stephanou E.G., Horii Y., and Kannan K. Emerging contaminants in car interiors: evaluating the impact of airborne PBDEs and PBDD/Fs. Environ. Sci. Technol. 42 (2008) 6431-6436
25. Olsman H., Engwall M., Kammann U., Klempt M., Otte J., van Bavel B., and Hollert H. Relative differences in aryl hydrocarbon receptor-mediated response for 18 polybrominated and mixed halogenated dibenzo-p-dioxins and -furans in cell lines from four different species. Environ. Toxicol. Chem. 26 (2007) 2448-2454
26. Sakai S., Watanabe J., Honda Y., Takatsuki H., Aoki I., Futamatsu M., and Shiozaki K. Combustion of brominated flame retardants and behavior of its byproducts. Chemosphere 42 (2001) 519-531
27. Samara F., Gullett B.K., Harrison R.O., Chu A., and Clark G.C. Determination of relative assay response factors for toxic chlorinated and brominated dioxins/furans using an enzyme immunoassay (EIA) and a chemically-activated luciferase gene expression cell bioassay (CALUX). Environ. Int. 35 (2009) 588-593
28. Soderstrom G., Sellstrom U., De Wit C.A., and Tysklind M. Photolytic debromination of decabromodiphenyl ether (BDE 209). Environ. Sci. Technol. 38 (2004) 127-132
29. Stapleton H.M., Allen J.G., Kelly S.M., Konstantinov A., Klosterhaus S., Watkins D., and McClean M.D. Alternate and new brominated flame retardants detected in US house dust. Environ. Sci. Technol. 42 (2008) 6910-6916
30. Takigami H., Suzuki G., Hirai Y., and Sakai S.-i. Transfer of brominated flame retardants from components into dust inside television cabinets. Chemosphere 73 (2008) 161-169
31. Tasaki T., Takasuga T., Osako M., and Sakai S.-i. Substance flow analysis of brominated flame retardants and related compounds in waste TV sets in Japan. Waste Manage. 24 (2004) 571-580
32. van Bavel B., Hardell L., Kitti A., Liljedahl M., Karlsson M., Pettersson A., and Lindström G. High levels of PBDEs in 5% of 220 blood samples from the Swedish population. Organohalogen Compd. 58 (2002) 161-164
33. van Bavel B., Ericson I., Björnfoth H., Hagberg J., and Lindström G. Development of an analytical method for the detection of PBDD/DF in environmental samples. Organohalogen Compd. 66 (2004) 106-110
34. Van den Berg M., Birnbaum L., Bosveld A.T.C., Brunström B., Cook P., Feeley M., Giesy J.P., Hanberg A., Hasegawa R., Kennedy S.W., Kubiak T., Larsen J.C., van Leeuwen F.X.R., Liem A.K.D., Nolt C., Peterson R.E., Poellinger L., Safe S., Schrenk D., Tillitt D., Tysklind M., Younes M., Wærn F., and Zacharewski T. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and WILDLIFE. Environ. Health Perspect. 106 (1998) 775-792
35. Van den Berg M., Birnbaum L.S., Denison M., De Vito M., Farland W., Feeley M., Fiedler H., Hakansson H., Hanberg A., Haws L., Rose M., Safe S., Schrenk D., Tohyama C., Tritscher A., Tuomisto J., Tysklind M., and Walker N. The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol. Sci. 93 (2006) 223-241
36. Wang L.-C., and Chang-Chien G.-P. Characterizing the emissions of polybrominated dibenzo-p-dioxins and dibenzofurans from municipal and industrial waste incinerators. Environ. Sci. Technol. 41 (2007) 1159-1165
37. Wang L.-C., Tsai C.-H., Chang-Chien G.-P., and Hung C.-H. Characterization of polybrominated dibenzo-p-dioxins and dibenzofurans in different atmospheric environments. Environ. Sci. Technol. 42 (2008) 75-80
38. Weber R., and Kuch B. Relevance of BFRs and thermal conditions on the formation pathways of brominated and brominated-chlorinated dibenzodioxins and dibenzofurans. Environ. Int. 29 (2003) 699-710
39. Weil E.D., and Levchik S.V. Commercial flame retardancy of polyurethanes J. Fire Sci. 22 (2004) 183-210
40. Zhu J., Hou Y., Feng Y.-l., Shoeib M., and Harner T. Identification and determination of hexachlorocyclopentadienyl-dibromocyclooctane (HCDBCO) in residential indoor air and dust: a previously unreported halogenated flame retardant in the environment. Environ. Sci. Technol. 42 (2008) 386-391
41. Zober M.A., Ott M.G., Papke O., Senft K., and Germann C. Morbidity study of extruder personnel with potential exposure to brominated dioxins and furans. 1. Results of blood monitoring and immunological tests. Br. J. Ind. Med. 49 (1992) 532-544
42. Zota A.R., Rudel R.A., Morello-Frosch R.A., and Green Brody J. Elevated house dust and serum concentrations of PBDEs in California: unintended consequences of furniture flammability standards?. Environ. Sci. Technol. 42 (2008) 8158-8164