Determination of relative assay response factors for toxic chlorinated and brominated dioxins/furans using an enzyme immunoassay (EIA) and a chemically-activated luciferase gene expression cell bioassay (CALUX)

Environment International

Volumn 35, Issue 3, 2009, Pages 588-593

  Samara, Fatin ^a   Gullett, Brian K ^a   Harrison, Robert O ^b   Chu, Andrew ^c   Clark, George C ^c  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b CAPE Technologies   (United States)

^c Xenobiotic Detection Systems Inc   (United States)

Author keywords

CALUX; Dioxin like activity; ELISA; PBCDD F; PBDD F; PCDD F

Indexed keywords

BIOACTIVITY; BIOASSAY; ENZYMES; GENES; HEALTH RISKS; IMMUNOLOGY; ORGANIC POLLUTANTS;

CALUX; DIOXIN-LIKE ACTIVITIES; ELISA; PBCDD/F; PBDD/F; PCDD/F;

GENE EXPRESSION;

BIOASSAY; DIOXIN; ENZYME ACTIVITY; FURAN; GENE EXPRESSION; HEALTH RISK; IMMUNOASSAY; PUBLIC HEALTH; TOXICITY TEST;

EID: 61449245496     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2008.11.003     Document Type: Article

References (31)

1. Behnisch P.A., Hosoe K., and Sakai S. Bioanalytical screening methods for dioxins and dioxin-like compounds - a review of bioassay/biomarker technology. Environ Int 27 (2001) 413-439
2. Behnisch P.A., Hosoe K., and Sakai S. Brominated dioxin-like compounds: in vitro assessment in comparison to classical dioxin-like compounds and other polyaromatic compounds. Environ Int 29 (2003) 861-877
3. Birnbaum L.S., Morrissey R.E., and Harris M.W. Teratogenic effects of 2,3,7,8-tetrabromodibenzo-p-dioxin and 3 polybrominated dibenzofurans in C57BL/6N mice. Toxicol Appl Pharmacol 107 (1991) 141-152
4. Brown D.G., van Overmeire I., Goeyens L., Denison M.S., and Clark G.C. Analysis of brominated flame retardants and brominated dibenzodioxins and biphenyls for Ah receptor activation using the CALUX bioassay. Organohalog Compd 54 (2001) 12-15
5. Brown D.J., Chu M., Van Overmeire I., Chu A., and Clark G.C. Determination of REP values for the CALUX® bioassay and comparison to the WHO TEF values. Organohalog Compd 48 (2001) 211-214
6. Brown D.J., Van Overmeire I., Goeyens L., Denison M.S., De Vito M.J., and Clark G.C. Analysis of Ah receptor pathway activation by brominated flame retardants. Chemosphere 55 (2004) 1509-1518
7. Cape Technologies. L.L.C. Cape Technologies Calculation Module C: Excel workbook for iterative four parameter curve fit and analysis of sample data (2004)
8. Cape Technologies. L.L.C. Cape Technologies high performance dioxin/furan kit DF1 kit insert (IN-DF1) (2006)
9. Carlson R.E. High sensitivity immunoassay for polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans. United States Patent # 5,674,697. Ecochem Research, Inc. (Chaska, MN) (1997)
10. Carlson R.E., and Harrison R.O. Measurement of PCDD/F TEQ by immunoassay: concept development and validation. Organohalog Compd 35 (1998) 97-100
11. Denison, M.S.; Brouwer, A.; Clark, G.C., Bioassay for detecting 2,3,7,8-tetrachlorodibenzo-para-dioxin and TCDD-like compounds and novel recombinant cell line useful therefor. United States Patent # 5,854,010 (online at http://www.dioxins.com/images/Calux-patent%20copy.gif). Xenobiotic Detection Systems Inc. 1998. Accessed April 2008.
12. DeVito M.J., Diliberto J.J., Ross D.G., Menache M.G., and Birnbaum L.S. Dose-response relationships for polyhalogenated dioxins and dibenzofurans following subchronic treatment in mice I. CYP1A1 and CYP1A2 enzyme activity in liver, lung, and skin. Toxicol Appl Pharmacol 147 (1997) 267-280
13. Ebert J., and Bahadir M. Formation of PBDD/F from flame-retarded plastic materials under thermal stress. Environ Int 29 (2003) 711-716
14. Garrison P.M., Tullis K., Aarts J., Brouwer A., Giesy J.P., and Denison M.S. Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals. Fundam Appl Toxicol 30 (1996) 194-203
15. Harrison R.O., and Carlson R.E. An immunoassay for TEQ screening of dioxin/furan samples: current status of assay and applications development. Chemosphere 34 (1997) 915-928
16. Hornung M.W., Zabel E.W., and Peterson R.E. Toxic equivalency factors of polybrominated dibenzo-p-dioxin, dibenzofuran, biphenyl, and polyhalogenated diphenyl ether congeners based on rainbow trout early life stage mortality. Toxicol Appl Pharmacol 140 (1996) 227-234
17. Kedderis L.B., Mills J.J., Andersen M.E., and Birnbaum L.S. A physiologically based pharmacokinetic model for 2,3,7,8-tetrabromodibenzo-p-dioxin (TBDD) in the rat - tissue distribution and CYP1A induction. Toxicol Appl Pharmacol 121 (1993) 87-98
18. Mason G., Zacharewski T., Denomme M.A., Safe L., and Safe S. Polybrominated dibenzo-para-dioxin and related-compounds - quantitative in vivo and in vitro structure activity-relationships. Toxicology 44 (1987) 245-255
19. Nichkova M., Park E.K., Koivunen M.E., Kamita S.G., Gee S.J., Chuang J., et al. Immunochemical determination of dioxins in sediment and serum samples. Talanta 63 (2004) 1213-1223
20. Olsman H., Engwall M., Kammann U., Klempt M., Otte J., van Bavel B., et al. Relative differences in aryl hydrocarbon receptor-mediated response for 18 polybrominated and mixed halogenated dibenzo-p-dioxins and-furans in cell lines from four different species. Environ Toxicol Chem 26 (2007) 2448-2454
21. Poland A., and Knutson J.C. 2,3,7,8-Tetrachloro dibenzo-para-dioxin and related halogenated aromatic-hydrocarbons - examination of the mechanism of toxicity. Annu Rev Pharmacol Toxicol 22 (1982) 517-554
22. Poland A., Glover E., and Kende A.S. Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-para-dioxin by hepatic cytosol - evidence that binding species is receptor for induction of aryl-hydrocarbon hydroxylase. J Biol Chem 251 (1976) 4936-4946
23. Safe S. Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). Crit Rev Toxicol 21 (1990) 51-88
24. Safe S.H. Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. Crit Rev Toxicol 24 (1994) 87-149
25. Shan G., Leeman W.R., Gee S.J., Sanborn J.R., Jones A.D., Chang D.P.Y., et al. Highly sensitive dioxin immunoassay and its application to soil and biota samples. Anal Chim Acta 444 (2001) 169-178
26. Söderstrom G., and Marklund S. PBCDD and PBCDF from incineration of waste-containing brominated flame retardants. Environ Sci Technol 36 (2002) 1959-1964
27. Sugawara Y., Saito K., Ogawa M., Kobayashi S., Shan G.M., Sanborn J.R., et al. Development of dioxin toxicity evaluation method in human milk by enzyme-linked immunosorbent assay-assay validation for human milk. Chemosphere 46 (2002) 1471-1476
28. Van den Berg M., Birnbaum L., Bosveld A.T.C., Brunstrom B., Cook P., Feeley M., et al. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Environ Health Perspect 106 (1998) 775-792
29. Van den Berg M., Birnbaum L.S., Denison M., De Vito M., Farland W., Feeley M., et al. The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol Sci 93 (2006) 223-241
30. Watanabe I., and Sakai S. Environmental release and behavior of brominated flame retardants. Environ Int 29 (2003) 665-682
31. Weber L.W.D., and Greim H. The toxicity of brominated and mixed-halogenated dibenzo-p-dioxins and dibenzofurans: an overview. J Toxicol Environ Health 50 (1997) 195-215