Polymorphism (ALA16VAL) correlates with regional lymph node status in breast cancer

Cancer Genetics and Cytogenetics

Volumn 196, Issue 2, 2010, Pages 153-158

  Bica, Claudia Giuliano ^a   de Moura da Silva, Leonardo Leiria ^a   Toscani, Nadima Vieira ^a   Zettler, Cláudio Galleano ^a   do Valle Gottlieb, Maria Gabriela ^b   Alexandre, Cláudio Osmar Pereira ^a   Graudenz, Márcia Silveira ^a   Mânica da Cruz, Ivana Beatrice ^b  

^a UNIVERSIDADE FEDERAL DE CIÊNCIAS DA SAÚDE DE PORTO ALEGRE   (Brazil)

^b FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ESTROGEN RECEPTOR; KI 67 ANTIGEN; MANGANESE SUPEROXIDE DISMUTASE; PARAFFIN; PROGESTERONE RECEPTOR; PROTEIN P53; VALINE;

ADULT; ARTICLE; AXILLARY LYMPH NODE; BREAST CANCER; CANCER INVASION; CANCER RISK; CARCINOGENESIS; CONTROLLED STUDY; DNA EXTRACTION; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LEUKOCYTE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; METASTASIS POTENTIAL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ALANINE; BREAST NEOPLASMS; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; LYMPH NODES; MIDDLE AGED; POLYMORPHISM, GENETIC; SUPEROXIDE DISMUTASE; VALINE;

EID: 71649100810     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2009.09.011     Document Type: Article

References (32)

1. Chung-man Ho J., Zheng S., Comhair S.A., Farver C., and Erzurum S.C. Differential expression of manganese superoxide dismutase and catalase in lung cancer. Cancer Res 61 (2001) 8578-8585
2. Skrzydlewska E., Kozuszko B., Sulkowska M., Bogdan Z., Kozlowski M., Snarska J., Puchalski Z., Sulkowski S., and Skrzydlewski Z. Antioxidant potential in esophageal, stomach and colorectal cancers. Hepatogastroenterology 50 (2003) 126-131
3. Tsanou E., Loachim E., Briasoulis E., Damala K., Charchanti A., Karavasilis V., Pavlidis N., and Agnantis N.J. Immunohistochemical expression of superoxide dismutase (MnSOD) anti-oxidant enzyme in invasive breast carcinoma. Histol Histopathol 19 (2004) 807-813
4. Hyoudou K., Nishikawa M., Kobayashi Y., Ikemura M., Yamashita F., and Hashida M. SOD derivatives prevent metastatic tumor growth aggravated by tumor removal. Clin Exp Metastasis 25 (2008) 531-536
5. Connor K.M., Hempel N., Nelson K.K., Dabiri G., Gamarra A., Belarmino J., Van De Water L., Mian B.M., and Melendez J.A. Manganese superoxide dismutase enhances the invasive and migratory activity of tumor cells. Cancer Res 67 (2007) 10260-10267
6. Shimoda-Matsubayashi S., Matsumine H., Kobayashi T., Nakagawa-Hattori Y., Shimizu Y., and Mizuno Y. Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene. A predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's disease. Biochem Biophys Res Commun 226 (1996) 561-565
7. Sutton A., Khoury H., Prip-Buus C., Cepanec C., Pessayre D., and Degoul F. The Ala16Val genetic dimorphism modulates the import of human manganese superoxide dismutase into rat liver mitochondria. Pharmacogenet 13 (2003) 145-157
8. Mitrunen K., Sillanpää P., Kataja V., Eskelinen M., Kosma V.M., Benhamou S., Uusitupa M., and Hirvonen A. Association between manganese superoxide dismutase (MnSOD) gene polymorphism and breast cancer risk. Carcinogenesis 22 (2001) 827-829
9. Millikan R.C., Player J., de Cotret A.R., Moorman P., Pittman G., Vannappagari V., Tse C.K., and Keku T. Manganese superoxide dismutase Ala-9Val polymorphism and risk of breast cancer in a population-based case-control study of African Americans and whites. Breast Cancer Res 6 (2004) 264-274
10. Cai Q., Shu X.O., Wen W., Cheng J.R., Dai Q., Gao Y.T., and Zheng W. Genetic polymorphism in the manganese superoxide dismutase gene, antioxidant intake, and breast cancer risk: results from the Shanghai Breast Cancer Study. Breast Cancer Res 6 (2004) 647-655
11. Bergman M., Ahnström M., Palmebäck Wegman P., and Wingren S. Polymorphism in the manganese superoxide dismutase (MnSOD) gene and risk of breast cancer in young women. J Cancer Res Clin Oncol 131 (2005) 439-444
12. Slanger T.E., Chang-Claude J., and Wang-Gohrke S. Manganese superoxide dismutase Ala-9Val polymorphism, environmental modifiers, and risk of breast cancer in a German population. Cancer Causes Control 17 (2006) 1025-1031
13. Cox D.G., Tamimi R.M., and Hunter D.J. Gene x gene interaction between MnSOD and GPX-1 and breast cancer risk: a nested case-control study. BMC Cancer 6 (2006) 217
14. Bica C.G., de Moura da Silva L.L., Toscani N.V., da Cruz I.B., Sá G., Graudenz M.S., and Zettler C.G. MnSOD gene polymorphism association with steroid-dependent cancer. Pathol Oncol Res 15 (2009) 19-24
15. Ambrosone C.B., Freudenheim J.L., Thompson P.A., Bowman E., Vena J.E., Marshall J.R., Graham S., Laughlin R., Nemoto T., and Shields P.G. Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer. Cancer Res 59 (1999) 602-606
16. Tamimi R.M., Hankinson S.E., Spiegelman D., Colditz G.A., and Hunter D.J. Manganese superoxide dismutase polymorphism, plasma antioxidants, cigarette smoking, and risk of breast cancer. Cancer Epidemiol Biomarkers Prev 13 (2004) 989-996
17. Kakko S., Päivänsalo M., Koistinen P., Kesäniemi Y.A., Kinnula V.L., and Savolainen M.J. The signal sequence polymorphism of the MnSOD gene is associated with the degree of carotid atherosclerosis. Atherosclerosis 168 (2003) 147-152
18. Hiroi S., Harada H., Nishi H., Satoh M., Nagai R., and Kimura A. Polymorphisms in the SOD2 and HLA-DRB1 genes are associated with nonfamilial idiopathic dilated cardiomyopathy in Japanese. Biochem Biophys Res Commun 261 (1999) 332-339
19. Gottlieb M.G., Schwanke C.H., Santos A.F., Jobim P.F., Müssel D.P., and da Cruz I.B. Association among oxidized LDL levels, MnSOD, apolipoprotein E polymorphisms, and cardiovascular risk factors in a south Brazilian region population. Genet Mol Res 4 (2005) 691-703
20. Montano M.A., Barrio Lera J.P., Gottlieb M.G., Schwanke C.H., da Rocha M.I., Manica-Cattani M.F., Dos Santos G.F., and da Cruz I.B. Association between manganese superoxide dismutase (MnSOD) gene polymorphism and elderly obesity. Mol Cell Biochem 328 (2009) 33-40
21. Fujimoto H., Taguchi J.I., Imai Y., Ayabe S., Hashimoto H., Kobayashi H., Ogasawara K., Aizawa T., Yamakado M., Nagai R., and Ohno M. Manganese superoxide dismutase polymorphism affects the oxidized low-density lipoprotein-induced apoptosis of macrophages and coronary artery disease. Eur Heart J 29 (2008) 1267-1274
22. Taufer M., Peres A., de Andrade V.M., de Oliveira G., Sá G., do Canto M.E., dos Santos A.R., Bauer M.E., and da Cruz I.B. Is the Val16Ala manganese superoxide dismutase polymorphism associated with the aging process?. J Gerontol A Biol Sci Med Sci 60 (2005) 432-438
23. Agnoletto M.H., Guecheva T.N., Donde F., de Oliveira A.F., Franke F., Cassini C., Salvador M., Henriques J.A., and Saffi J. Association of low repair efficiency with high hormone receptor expression and SOD activity in breast cancer patients. Clin Biochem 40 (2007) 1252-1258
24. Da Cruz I.B., Oliveira G., Taufer M., Leal N.F., Schwanke C.H., Glock L., Moriguchi Y., and Moriguchi E.H. Angiotensin I-converting enzyme gene polymorphism in two ethnic groups living in Brazil's southern region: association with age. J Gerontol A Biol Sci Med Sci 58 (2003) M851-M856
25. Parra F.C., Amado R.C., and Lambertucci J.R. Color and genomic ancestry in Brazilians. Proc Natl Acad Sci USA 100 (2003) 177-182
26. Mattevi V.S., Zembrzuski V.M., and Hutz M.H. Association analysis of genes involved in the leptin-signaling pathway with obesity in Brazil. Int J Obesity 26 (2002) 1979-1985
27. Marrero A.R., Das Neves Leite F.P., De Almeida Carvalho B., Peres L.M., Kommers T.C., Da Cruz I.M., Salzano F.M., Ruiz-Linares A., Da Silva Júnior W.A., and Bortolini M.C. Heterogeneity of the genome ancestry of individuals classified as White in the state of Rio Grande do Sul, Brazil. Am J Hum Biol 17 (2005) 496-506
28. Sutton A., Imbert A., Igoudjil A., Descatoire V., Cazanave S., Pessayre D., and Degoul F. The manganese superoxide dismutase Ala16Val dimorphism modulates both mitochondrial import and mRNA stability. Pharmacogenet Genomics 15 (2005) 311-319
29. Soini Y., Vakkala M., Kahlos K., Pääkkö P., and Kinnula V. MnSOD expression is less frequent in tumor cells of invasive breast carcinomas than in in situ carcinomas or nonneoplastic breast epithelial cells. J Pathol 195 (2001) 156-162
30. Oberley L.W. Mechanism of the tumor suppressive effect of MnSOD overexpression. Biomed Pharmacother 59 (2005) 143-148
31. Kim K.H., Rodriguez A.M., Carrico P.M., and Melendez J.A. Potential mechanisms for the inhibition of tumor cell growth by manganese superoxide dismutase. Antioxid Redox Signal 3 (2001) 361-373
32. Kattan Z., Minig V., Leroy P., Dauça M., and Becuwe P. Role of manganese superoxide dismutase on growth and invasive properties of human estrogen-independent breast cancer cells. Breast Cancer Res Treat 108 (2008) 203-215