A Single Nucleotide Polymorphism in the Vascular Endothelial Growth Factor Gene Is Associated with Recurrence of Hepatocellular Carcinoma after Transplantation

Archives of Medical Research

Volumn 40, Issue 7, 2009, Pages 565-570

  Wu, Li Ming ^a,b   Xie, Hai Yang ^a,b   Zhou, Lin ^a,b   Yang, Zhe ^a,b   Zhang, Feng ^a,b   Zheng, Shu Sen ^a,b  

^a BEIJING HOSPITAL   (China)

^b First Affiliated Hospital   (China)

Author keywords

Hepatocellular carcinoma; Polymorphisms; Recurrence; Vascular endothelial growth factor

Indexed keywords

ALPHA FETOPROTEIN; VASCULOTROPIN;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER RECURRENCE; CANCER RISK; CANCER SURVIVAL; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC RISK; HISTOPATHOLOGY; HUMAN; LIVER CELL CARCINOMA; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PROGNOSIS; RECURRENT CANCER; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVAL TIME; TUMOR THROMBUS; TUMOR VOLUME;

ADULT; AGED; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CARCINOMA, HEPATOCELLULAR; FEMALE; GENOTYPE; HAPLOTYPES; HUMANS; KAPLAN-MEIERS ESTIMATE; LINKAGE DISEQUILIBRIUM; LIVER NEOPLASMS; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; POLYMORPHISM, SINGLE NUCLEOTIDE; PROPORTIONAL HAZARDS MODELS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; YOUNG ADULT;

EID: 71649100485     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcmed.2009.07.011     Document Type: Article

References (26)

1. Lau W.Y., and Lai E.C. Hepatocellular carcinoma: current management and recent advances. Hepatobiliary Pancreat Dis Int 7 (2008) 237-257
2. Wild C.P., and Hall A.J. Primary prevention of hepatocellular carcinoma in developing countries. Mutat Res 462 (2000) 381-393
3. Marsh J.W., Finkelstein S.D., Demetris A.J., et al. Genotyping of hepatocellular carcinoma in liver transplant recipients adds predictive power for determining recurrence-free survival. Liver Transplantation 9 (2003) 664-671
4. Ferrara N., Gerber H.P., and LeCouter J. The biology of VEGF and its receptors. Nat Med 9 (2003) 669-676
5. Poon R.T., Lau C., Pang R., et al. High serum vascular endothelial growth factor levels predict poor prognosis after radiofrequency ablation of hepatocellular carcinoma: importance of tumor biomarker in ablative therapies. Ann Surg Oncol 14 (2007) 1835-1845
6. Pang R.W., Joh J.W., Johnson P.J., et al. Biology of hepatocellular carcinoma. Ann Surg Oncol 15 (2008) 962-971
7. Zhang Q., Chen X., Zhou J., et al. CD147, MMP-2, MMP-9 and MVD-CD34 are significant predictors of recurrence after liver transplantation in hepatocellular carcinoma patients. Cancer Biol Ther 5 (2006) 808-814
8. Kong S.Y., Park J.W., Lee J.A., et al. Association between vascular endothelial growth factor gene polymorphisms and survival in hepatocellular carcinoma patients. Hepatology 46 (2007) 446-455
9. Wu L., Xu X., Shen J., et al. MDR1 gene polymorphisms and risk of recurrence in patients with hepatocellular carcinoma after liver transplantation. J Surg Oncol 96 (2007) 62-68
10. Wu L.M., Zhang F., Xie H.Y., et al. MMP2 promoter polymorphism (C-1306T) and risk of recurrence in patients with hepatocellular carcinoma after transplantation. Clin Genet 73 (2008) 273-278
11. Li X.D., Wu L.M., Xie H.Y., et al. No association exists between E-cadherin gene polymorphism and tumor recurrence in patients with hepatocellular carcinoma after transplantation. Hepatobiliary Pancreat Dis Int 6 (2007) 254-258
12. Carlson C.S., Eberle M.A., Rieder M.J., et al. Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet 74 (2004) 106-120
13. Solé X., Guinó E., Valls J., et al. SNPStats: a web tool for the analysis of association studies. Bioinformatics 22 (2006) 1928-1929
14. Heist R.S., Zhai R., Liu G., et al. VEGF polymorphisms and survival in early-stage non-small-cell lung cancer. J Clin Oncol 26 (2008) 856-862
15. Kim J.G., Chae Y.S., Sohn S.K., et al. Vascular endothelial growth factor gene polymorphisms associated with prognosis for patients with colorectal cancer. Clin Cancer Res 14 (2008) 62-66
16. Kim J.G., Sohn S.K., Chae Y.S., et al. Vascular endothelial growth factor gene polymorphisms associated with prognosis for patients with gastric cancer. Ann Oncol 18 (2007) 1030-1036
17. Hefler L.A., Mustea A., Könsgen D., et al. Vascular endothelial growth factor gene polymorphisms are associated with prognosis in ovarian cancer. Clin Cancer Res 13 (2007) 898-901
18. Sfar S., Hassen E., Saad H., et al. Association of VEGF genetic polymorphisms with prostate carcinoma risk and clinical outcome. Cytokine 35 (2006) 21-28
19. Kim E.J., Jeong P., Quan C., et al. Genotypes of TNF-alpha, VEGF, hOGG1, GSTM1, and GSTT1: useful determinants for clinical outcome of bladder cancer. Urology 65 (2005) 70-75
20. Jin Q., Hemminki K., Enquist K., et al. Vascular endothelial growth factor polymorphisms in relation to breast cancer development and prognosis. Clin Cancer Res 11 (2005) 3647-3653
21. Inoue K., Awata T., Kurihara S., et al. A common polymorphism in the 5′-untranslated region of the VEGF gene is associated with diabetic retinopathy in type 2 diabetes. Diabetes 51 (2002) 1635-1639
22. Shahbazi M., Fryer A.A., Pravica V., et al. Vascular endothelial growth factor gene polymorphisms are associated with acute renal allograft rejection. J Am Soc Nephrol 13 (2002) 260-264
23. Mohammadi M., Ollier W.E., and Hutchinson I.V. A functional association study of VEGF gene promoter polymorphisms with VEGF expression by stimulated pbm cells. Hum Immunol 64 (2003) S125
24. Renner W., Kotschan S., Hoffmann C., et al. A common 936 C/T mutation in the gene for vascular endothelial growth factor is associated with vascular endothelial growth factor plasma levels. J Vasc Res 37 (2000) 443-448
25. Hua Z., Lv Q., Ye W., et al. MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia. PLoS ONE 1 (2006) e116
26. Landi D., Gemignani F., Naccarati A., et al. Polymorphisms within micro-RNA-binding sites and risk of sporadic colorectal cancer. Carcinogenesis 29 (2008) 579-584