Multiple roles for BMP signaling in cardiac development

Drug Discovery Today: Therapeutic Strategies

Volumn 5, Issue 4, 2008, Pages 209-214

  Yuasa, Shinsuke ^a   Fukuda, Keiichi ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 10; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 5; BONE MORPHOGENETIC PROTEIN 6; CHORDIN; FOLLISTATIN; NOGGIN; OSTEOGENIC PROTEIN 1; UNCLASSIFIED DRUG;

ADULT STEM CELL; BINDING AFFINITY; CELL DIFFERENTIATION; CELL MATURATION; CELL MIGRATION; CELL PROLIFERATION; CELL REGENERATION; EMBRYONIC STEM CELL; HEART DEVELOPMENT; HEART MUSCLE CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION;

EID: 71649093032     PISSN: 17406773     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddstr.2008.12.001     Document Type: Review

References (53)

1. Ashe H.L. BMP signalling: synergy and feedback create a step gradient. Curr. Biol. 15 (2005) R375-R377
2. Kingsley D.M. The TGF-[beta] superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 8 (1994) 133-146
3. Urist M.R. Bone: formation by autoinduction. Science 150 (1965) 893-899
4. Wozney J.M., et al. Novel regulators of bone formation: molecular clones and activities. Science 242 (1988) 1528-1534
5. Dale L., et al. Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development. Development (Cambridge, England) 115 (1992) 573-585
6. Bodmer R. The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development 118 (1993) 719-729
7. Frasch M. Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo. Nature 374 (1995) 464-467
8. Andree B., et al. BMP-2 induces ectopic expression of cardiac lineage markers and interferes with somite formation in chicken embryos. Mech. Dev. 70 (1998) 119-131
9. Reese D.E., et al. Negative regulation of midline vascular development by the notochord. Dev. Cell 6 (2004) 699-708
10. Hatada Y., and Stern C.D. A fate map of the epiblast of the early chick embryo. Development 120 (1994) 2879-2889
11. Garcia-Martinez V., and Schoenwolf G.C. Primitive-streak origin of the cardiovascular system in avian embryos. Dev. Biol. 159 (1993) 706-719
12. Lyons K.M., et al. Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development. Mech. Dev. 50 (1995) 71-83
13. Neuhaus H., et al. Heart specific expression of mouse BMP-10 a novel member of the TGF-[beta] superfamily. Mech. Dev. 80 (1999) 181-184
14. Winnier G., et al. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev. 9 (1995) 2105-2116
15. Lough J., et al. Combined BMP-2 and FGF-4, but neither factor alone, induces cardiogenesis in non-precardiac embryonic mesoderm. Dev. Biol. 178 (1996) 198-202
16. Zhang H., and Bradley A. Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development. Development 122 (1996) 2977-2986
17. Lee K.Y., et al. Bmp2 is critical for the murine uterine decidual response. Mol. Cell. Biol. 27 (2007) 5468-5478
18. Ma L., et al. Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning. Development 132 (2005) 5601-5611
19. Fujiwara T., et al. Distinct requirements for extra-embryonic and embryonic bone morphogenetic protein 4 in the formation of the node and primitive streak and coordination of left-right asymmetry in the mouse. Development 129 (2002) 4685-4696
20. Liu W., et al. Bmp4 signaling is required for outflow-tract septation and branchial-arch artery remodelling. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 4489-4494
21. Jiao K., et al. An essential role of Bmp4 in the atrioventricular septation of the mouse heart. Genes Dev. 17 (2003) 2362-2367
22. Ebisawa T., et al. Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation. J. Cell Sci. 112 (1999) 3519-3527
23. Dudley A.T., and Robertson E.J. Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos. Dev. Dynam. 208 (1997) 349-362
24. Solloway M.J., et al. Mice lacking Bmp6 function. Dev. Genet. 22 (1998) 321-339
25. Kim R.Y., et al. Bmp6 and Bmp7 are required for cushion formation and septation in the developing mouse heart. Dev. Biol. 235 (2001) 449-466
26. Yamagishi T., et al. Expression of bone morphogenetic protein-5 gene during chick heart development: possible roles in valvuloseptal endocardial cushion formation. Anat. Rec. 264 (2001) 313-316
27. Kingsley D.M., et al. The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGF[beta] superfamily. Cell 71 (1992) 399-410
28. Solloway M.J., and Robertson E.J. Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. Development (Cambridge, England) 126 (1999) 1753-1768
29. Chen H., et al. BMP10 is essential for maintaining cardiac growth during murine cardiogenesis. Development 131 (2004) 2219-2231
30. Hogan B.L.M. Bone morphogenetic proteins in development. Curr. Opin. Genet. Dev. 6 (1996) 432-438
31. Massague J., and Chen Y.G. Controlling TGF-beta signaling. Genes Dev. 14 (2000) 627-644
32. Avsian-Kretchmer O., and Hsueh A.J.W. Comparative genomic analysis of the eight-membered ring cystine knot-containing bone morphogenetic protein antagonists. Mol. Endocrinol. (Baltimore, MD) 18 (2004) 1-12
33. Ladd A.N., et al. Regulation of avian cardiac myogenesis by activin/TGFbeta and bone morphogenetic proteins. Dev. Biol. 204 (1998) 407-419
34. Streit A., et al. Chordin regulates primitive streak development and the stability of induced neural cells, but is not sufficient for neural induction in the chick embryo. Development 125 (1998) 507-519
35. Yuasa S., et al. Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells. Nat. Biotechnol. 23 (2005) 607-611
36. Fletcher R.B., et al. Expression of Xenopus tropicalis noggin1 and noggin2 in early development: two noggin genes in a tetrapod. Gene Expr. Patterns 5 (2004) 225-230
37. Faure S., et al. Endogenous patterns of BMP signaling during early chick development. Dev. Biol. 244 (2002) 44-65
38. Antin P.B., et al. Precocious expression of cardiac troponin T in early chick embryos is independent of bone morphogenetic protein signaling. Dev. Dyn. 225 (2002) 135-141
39. Tirosh-Finkel L., et al. Mesoderm progenitor cells of common origin contribute to the head musculature and the cardiac outflow tract. Development 133 (2006) 1943-1953
40. Matsui H., et al. Induction of initial cardiomyocyte alpha-actin - smooth muscle alpha-actin - in cultured avian pregastrula epiblast: a role for nodal and BMP antagonist. Dev. Dyn. 233 (2005) 1419-1429
41. Monzen K., et al. Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4. Mol. Cell. Biol. 19 (1999) 7096-7105
42. Kami D., et al. Gremlin enhances the determined path to cardiomyogenesis. PLoS ONE 3 (2008) e2407
43. Evans M.J., and Kaufman M.H. Establishment in culture of pluripotential cells from mouse embryos. Nature 292 (1981) 154-156
44. Zhang P., et al. Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells. Blood 111 (2008) 1933-1941
45. Hong S., et al. Development of efficient cardiac differentiation method of mouse embryonic stem cells. Key Eng. Mater. 342-343 (2007) 25-28
46. Hao J., et al. Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells. PLoS ONE 3 (2008) e2904
47. Kumar D., and Sun B. Transforming growth factor-[beta]2 enhances differentiation of cardiac myocytes from embryonic stem cells. Biochem. Biophys. Res. Commun. 332 (2005) 135-141
48. Behfar A., et al. Stem cell differentiation requires a paracrine pathway in the heart. FASEB J. 16 (2002) 1558-1566
49. Laflamme M.A., et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat. Biotechnol. 25 (2007) 1015-1024
50. Hahn J.-Y., et al. Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and therapeutic efficacy for myocardial infarction. J. Am. Coll. Cardiol. 51 (2008) 933-943
51. Bartunek J., et al. Pretreatment of adult bone marrow mesenchymal stem cells with cardiomyogenic growth factors and repair of the chronically infarcted myocardium. Am. J. Physiol. Heart Circ. Physiol. 292 (2007) H1095-H1104
52. Yoon J., et al. Differentiation, engraftment and functional effects of pre-treated mesenchymal stem cells in a rat myocardial infarct model. Acta Cardiol. 60 (2005) 277-284
53. Chang S.-A., et al. Impact of myocardial infarct proteins and oscillating pressure on the differentiation of mesenchymal stem cells: effect of acute myocardial infarction on stem cell differentiation. Stem Cells 26 (2008) 1901-1912