Excellent correlation between cathepsin B inhibition and cytotoxicity for a series of palladacycles

Dalton Transactions

Volumn , Issue 48, 2009, Pages 10731-10735

  Spencer, John ^a   Casini, Angela ^b   Zava, Olivier ^b   Rathnam, Rajendra P ^a   Velhanda, Santosh K ^a   Pfeffer, Michel ^c   Callear, Samantha K ^d   Hursthouse, Michael B ^d   Dyson, Paul J ^b  

^a UNIVERSITY OF GREENWICH   (United Kingdom)

^b EPFL   (Switzerland)

^c UNIVERSITÉ LOUIS PASTEUR   (France)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CYTOTOXIC AGENTS; DIMERIC COMPLEXES; FERROCENES; IN-VITRO; MONOMERIC COMPLEXES; NMR SPECTROSCOPY; PALLADACYCLES;

CHLORINE COMPOUNDS; DYES; ETHANE; HYDROGEN SULFIDE; IRON COMPOUNDS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PALLADIUM; SINGLE CRYSTALS; X RAY CRYSTALLOGRAPHY;

PALLADIUM COMPOUNDS;

1,1' BIS(DIPHENYLPHOSPHINO)FERROCENE; 1,1'-BIS(DIPHENYLPHOSPHINO)FERROCENE; 1,3,5 TRIAZA 7 PHOSPHAADAMANTANE; 1,3,5-TRIAZA-7-PHOSPHAADAMANTANE; ADAMANTANE; CATHEPSIN B; COORDINATION COMPOUND; DRUG DERIVATIVE; FERROUS ION; ORGANOPHOSPHORUS COMPOUND; PALLADIUM; PHOSPHINE DERIVATIVE;

ARTICLE; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; HUMAN; METABOLISM; TUMOR CELL LINE; X RAY CRYSTALLOGRAPHY;

ADAMANTANE; CATHEPSIN B; CELL LINE, TUMOR; COORDINATION COMPLEXES; CRYSTALLOGRAPHY, X-RAY; FERROUS COMPOUNDS; HUMANS; MOLECULAR CONFORMATION; ORGANOPHOSPHORUS COMPOUNDS; PALLADIUM; PHOSPHINES;

EID: 71549169253     PISSN: 14779226     EISSN: 14779234     Source Type: Journal    
DOI: 10.1039/b912096c     Document Type: Article

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