-
1
-
-
0020286856
-
Survival and viability of nonculturable Escherichia coli and Vibrio cholerae in the estuarine and marine environment
-
Xu H., Roberts N., Singleton F.L., Attwell R.W., Grimes D.J., and Colwell R.R. Survival and viability of nonculturable Escherichia coli and Vibrio cholerae in the estuarine and marine environment. Microb Ecol 8 (1982) 313-323
-
(1982)
Microb Ecol
, vol.8
, pp. 313-323
-
-
Xu, H.1
Roberts, N.2
Singleton, F.L.3
Attwell, R.W.4
Grimes, D.J.5
Colwell, R.R.6
-
2
-
-
0031196186
-
Viable but non-culturable and dormant bacteria: time to resolve an oxymoron and a misnomer?
-
Barer M.R. Viable but non-culturable and dormant bacteria: time to resolve an oxymoron and a misnomer?. J Med Microbiol 46 (1997) 629-631
-
(1997)
J Med Microbiol
, vol.46
, pp. 629-631
-
-
Barer, M.R.1
-
3
-
-
34249949516
-
Recovery in culture of viable but nonculturable Vibrio parahaemolyticus: regrowth or resuscitation?
-
Coutard F., Crassous P., Droguet M., Gobin E., Colwell R.R., Pommepuy M., and Hervio-Heath D. Recovery in culture of viable but nonculturable Vibrio parahaemolyticus: regrowth or resuscitation?. ISME J 1 (2007) 111-120
-
(2007)
ISME J
, vol.1
, pp. 111-120
-
-
Coutard, F.1
Crassous, P.2
Droguet, M.3
Gobin, E.4
Colwell, R.R.5
Pommepuy, M.6
Hervio-Heath, D.7
-
4
-
-
8344225373
-
Role of catalase and oxyR in the viable but nonculturable state of Vibrio vulnificus
-
Kong I.-S., Bates T.C., Hulsmann A., Hassan H., Smith B.E., and Oliver J.D. Role of catalase and oxyR in the viable but nonculturable state of Vibrio vulnificus. FEMS Microbiol Ecol 50 (2004) 133-142
-
(2004)
FEMS Microbiol Ecol
, vol.50
, pp. 133-142
-
-
Kong, I.-S.1
Bates, T.C.2
Hulsmann, A.3
Hassan, H.4
Smith, B.E.5
Oliver, J.D.6
-
5
-
-
33847682955
-
Isolation and characterization of a cold-induced nonculturable suppression mutant of Vibrio vulnificus
-
Abe A., Ohashi E., Ren H., Hayashi T., and Endo H. Isolation and characterization of a cold-induced nonculturable suppression mutant of Vibrio vulnificus. Microbiol Res 162 (2007) 130-138
-
(2007)
Microbiol Res
, vol.162
, pp. 130-138
-
-
Abe, A.1
Ohashi, E.2
Ren, H.3
Hayashi, T.4
Endo, H.5
-
6
-
-
23844471922
-
Contact-dependent inhibition of growth in Escherichia coli
-
Aoki S.K., Pamma R., Hernday A.D., Bickham J.E., Braaten B.A., and Low D.A. Contact-dependent inhibition of growth in Escherichia coli. Science 309 (2005) 1245-1248
-
(2005)
Science
, vol.309
, pp. 1245-1248
-
-
Aoki, S.K.1
Pamma, R.2
Hernday, A.D.3
Bickham, J.E.4
Braaten, B.A.5
Low, D.A.6
-
7
-
-
52649136629
-
Contact-dependent growth inhibition requires the essential outer membrane protein BamA (YaeT) as the receptor and the inner membrane transport protein AcrB
-
Aoki S.K., Malinverni J.C., Jacoby K., Thomas B., Pamma R., Trinh B.N., Remers S., Webb J., Braaten B.A., Silhavy T.J., et al. Contact-dependent growth inhibition requires the essential outer membrane protein BamA (YaeT) as the receptor and the inner membrane transport protein AcrB. Mol Microbiol 70 (2008) 323-340
-
(2008)
Mol Microbiol
, vol.70
, pp. 323-340
-
-
Aoki, S.K.1
Malinverni, J.C.2
Jacoby, K.3
Thomas, B.4
Pamma, R.5
Trinh, B.N.6
Remers, S.7
Webb, J.8
Braaten, B.A.9
Silhavy, T.J.10
-
8
-
-
34548139422
-
Structure and function of an essential component of the outer membrane protein assembly machine
-
Kim S., Malinverni J.C., Sliz P., Silhavy T.J., Harrison S.C., and Kahne D. Structure and function of an essential component of the outer membrane protein assembly machine. Science 317 (2007) 961-964
-
(2007)
Science
, vol.317
, pp. 961-964
-
-
Kim, S.1
Malinverni, J.C.2
Sliz, P.3
Silhavy, T.J.4
Harrison, S.C.5
Kahne, D.6
-
9
-
-
63049109309
-
Contact-dependent growth inhibition causes reversible metabolic downregulation in Escherichia coli
-
Aoki S.K., Webb J.S., Braaten B.A., and Low D.A. Contact-dependent growth inhibition causes reversible metabolic downregulation in Escherichia coli. J Bacteriol 191 (2009) 1777-1786
-
(2009)
J Bacteriol
, vol.191
, pp. 1777-1786
-
-
Aoki, S.K.1
Webb, J.S.2
Braaten, B.A.3
Low, D.A.4
-
10
-
-
36348968947
-
The evolution of contact-dependent inhibition in non-growing populations of Escherichia coli
-
Lemonnier M., Levin B.R., Romeo T., Garner K., Baquero M.R., Mercante J., Lemichez E., Baquero F., and Blazquez J. The evolution of contact-dependent inhibition in non-growing populations of Escherichia coli. Proc Biol Sci 275 (2008) 3-10
-
(2008)
Proc Biol Sci
, vol.275
, pp. 3-10
-
-
Lemonnier, M.1
Levin, B.R.2
Romeo, T.3
Garner, K.4
Baquero, M.R.5
Mercante, J.6
Lemichez, E.7
Baquero, F.8
Blazquez, J.9
-
11
-
-
47249086111
-
Genetic determinants of self identity and social recognition in bacteria
-
This fascinating study shows that different strains of Proteus mirabilis can recognize self from non-self, involving a locus denoted ids for identification of self. Two swarms of Proteus with different ids systems form boundaries on plates, which do not appear to be caused by a killing mechanism known to occur using bacteriocins called proticines, but could be caused by growth inhibition. This system has hallmarks of the immune system surveillance mechanisms distinguishing self from non-self.
-
Gibbs K.A., Urbanowski M.L., and Greenberg E.P. Genetic determinants of self identity and social recognition in bacteria. Science 321 (2008) 256-259. This fascinating study shows that different strains of Proteus mirabilis can recognize self from non-self, involving a locus denoted ids for identification of self. Two swarms of Proteus with different ids systems form boundaries on plates, which do not appear to be caused by a killing mechanism known to occur using bacteriocins called proticines, but could be caused by growth inhibition. This system has hallmarks of the immune system surveillance mechanisms distinguishing self from non-self.
-
(2008)
Science
, vol.321
, pp. 256-259
-
-
Gibbs, K.A.1
Urbanowski, M.L.2
Greenberg, E.P.3
-
12
-
-
62849109612
-
Flagellum mediates symbiosis
-
2-mediated negative feedback and maintaining this syntrophic relationship.
-
2-mediated negative feedback and maintaining this syntrophic relationship.
-
(2009)
Science
, vol.323
, pp. 1574
-
-
Shimoyama, T.1
Kato, S.2
Ishii, S.3
Watanabe, K.4
-
13
-
-
45749093808
-
Quorum sensing influences Vibrio harveyi growth rates in a manner not fully accounted for by the marker effect of bioluminescence
-
Nackerdien Z.E., Keynan A., Bassler B.L., Lederberg J., and Thaler D.S. Quorum sensing influences Vibrio harveyi growth rates in a manner not fully accounted for by the marker effect of bioluminescence. PLoS One 3 (2008) e1671
-
(2008)
PLoS One
, vol.3
-
-
Nackerdien, Z.E.1
Keynan, A.2
Bassler, B.L.3
Lederberg, J.4
Thaler, D.S.5
-
14
-
-
63749103609
-
New developments in microbial interspecies signaling
-
Shank E.A., and Kolter R. New developments in microbial interspecies signaling. Curr Opin Microbiol 12 (2009) 205-214
-
(2009)
Curr Opin Microbiol
, vol.12
, pp. 205-214
-
-
Shank, E.A.1
Kolter, R.2
-
15
-
-
33846245425
-
2: a possible counteroffensive strategy for interspecies competition
-
This study provides an excellent example of chemical warfare occurring between Streptococcus oligofermentans and S. mutants, the latter which causes cavities via lactic acid production. S. oligofermentans produces lactate oxidase to convert lactic acid to hydrogen peroxide, which inhibits growth of S. mutants but has a much lesser effect on S. oligofermentans. This study illustrates the complex metabolic interactions occurring between different bacterial species, some of which can directly affect cell growth.
-
2: a possible counteroffensive strategy for interspecies competition. Mol Microbiol 63 (2007) 872-880. This study provides an excellent example of chemical warfare occurring between Streptococcus oligofermentans and S. mutants, the latter which causes cavities via lactic acid production. S. oligofermentans produces lactate oxidase to convert lactic acid to hydrogen peroxide, which inhibits growth of S. mutants but has a much lesser effect on S. oligofermentans. This study illustrates the complex metabolic interactions occurring between different bacterial species, some of which can directly affect cell growth.
-
(2007)
Mol Microbiol
, vol.63
, pp. 872-880
-
-
Tong, H.1
Chen, W.2
Merritt, J.3
Qi, F.4
Shi, W.5
Dong, X.6
-
16
-
-
67649823687
-
Sporulation in mycobacteria
-
This provocative study indicates for the first time that mycobacteria form spores which confer resistance to environmental stress. This work will have a major impact on the way that mycobacterial dormancy is viewed and studied, and if it occurs in M. tuberculosis will provide new potential strategies to prevent and treat tuberculosis, which infects about one-third of the worlds population.
-
Ghosh J., Larsson P., Singh B., Pettersson B.M., Islam N.M., Sarkar S.N., Dasgupta S., and Kirsebom L.A. Sporulation in mycobacteria. Proc Natl Acad Sci U S A 106 (2009) 10781-10786. This provocative study indicates for the first time that mycobacteria form spores which confer resistance to environmental stress. This work will have a major impact on the way that mycobacterial dormancy is viewed and studied, and if it occurs in M. tuberculosis will provide new potential strategies to prevent and treat tuberculosis, which infects about one-third of the worlds population.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 10781-10786
-
-
Ghosh, J.1
Larsson, P.2
Singh, B.3
Pettersson, B.M.4
Islam, N.M.5
Sarkar, S.N.6
Dasgupta, S.7
Kirsebom, L.A.8
-
18
-
-
1542472730
-
New connections in the prokaryotic toxin-antitoxin network: relationship with the eukaryotic nonsense-mediated RNA decay system
-
Anantharaman V., and Aravind L. New connections in the prokaryotic toxin-antitoxin network: relationship with the eukaryotic nonsense-mediated RNA decay system. Genome Biol 4 (2003) R81
-
(2003)
Genome Biol
, vol.4
-
-
Anantharaman, V.1
Aravind, L.2
-
19
-
-
14244266086
-
Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes
-
Pandey D.P., and Gerdes K. Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes. Nucleic Acids Res 33 (2005) 966-976
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 966-976
-
-
Pandey, D.P.1
Gerdes, K.2
-
20
-
-
34548488930
-
Hypothetical functions of toxin-antitoxin systems
-
Magnuson R.D. Hypothetical functions of toxin-antitoxin systems. J Bacteriol 189 (2007) 6089-6092
-
(2007)
J Bacteriol
, vol.189
, pp. 6089-6092
-
-
Magnuson, R.D.1
-
21
-
-
63449102873
-
Bacterial toxin-antitoxin systems: more than selfish entities?
-
Van Melderen L., and Saavedra De Bast M. Bacterial toxin-antitoxin systems: more than selfish entities?. PLoS Genet 5 (2009) e1000437
-
(2009)
PLoS Genet
, vol.5
-
-
Van Melderen, L.1
Saavedra De Bast, M.2
-
22
-
-
33947330447
-
Chromosomal toxin-antitoxin loci can diminish large-scale genome reductions in the absence of selection
-
Szekeres S., Dauti M., Wilde C., Mazel D., and Rowe-Magnus D.A. Chromosomal toxin-antitoxin loci can diminish large-scale genome reductions in the absence of selection. Mol Microbiol 63 (2007) 1588-1605
-
(2007)
Mol Microbiol
, vol.63
, pp. 1588-1605
-
-
Szekeres, S.1
Dauti, M.2
Wilde, C.3
Mazel, D.4
Rowe-Magnus, D.A.5
-
23
-
-
46049106335
-
Chromosomal toxin-antitoxin systems may act as antiaddiction modules
-
Saavedra De Bast M., Mine N., and Van Melderen L. Chromosomal toxin-antitoxin systems may act as antiaddiction modules. J Bacteriol 190 (2008) 4603-4609
-
(2008)
J Bacteriol
, vol.190
, pp. 4603-4609
-
-
Saavedra De Bast, M.1
Mine, N.2
Van Melderen, L.3
-
25
-
-
35548944074
-
A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli
-
Kolodkin-Gal I., Hazan R., Gaathon A., Carmeli S., and Engelberg-Kulka H. A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli. Science 318 (2007) 652-655
-
(2007)
Science
, vol.318
, pp. 652-655
-
-
Kolodkin-Gal, I.1
Hazan, R.2
Gaathon, A.3
Carmeli, S.4
Engelberg-Kulka, H.5
-
26
-
-
37649005671
-
MazF, an mRNA interferase, mediates programmed cell death during multicellular Myxococcus development
-
Nariya H., and Inouye M. MazF, an mRNA interferase, mediates programmed cell death during multicellular Myxococcus development. Cell 132 (2008) 55-66
-
(2008)
Cell
, vol.132
, pp. 55-66
-
-
Nariya, H.1
Inouye, M.2
-
27
-
-
0041825422
-
Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA
-
Christensen S.K., Pedersen K., Hansen F.G., and Gerdes K. Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA. J Mol Biol 332 (2003) 809-819
-
(2003)
J Mol Biol
, vol.332
, pp. 809-819
-
-
Christensen, S.K.1
Pedersen, K.2
Hansen, F.G.3
Gerdes, K.4
-
28
-
-
34548496904
-
What is the benefit to Escherichia coli of having multiple toxin-antitoxin systems in its genome?
-
Tsilibaris V., Maenhaut-Michel G., Mine N., and Van Melderen L. What is the benefit to Escherichia coli of having multiple toxin-antitoxin systems in its genome?. J Bacteriol 189 (2007) 6101-6108
-
(2007)
J Bacteriol
, vol.189
, pp. 6101-6108
-
-
Tsilibaris, V.1
Maenhaut-Michel, G.2
Mine, N.3
Van Melderen, L.4
-
29
-
-
60849121408
-
HicA of Escherichia coli defines a novel family of translation-independent mRNA interferases in bacteria and archaea
-
Jorgensen M.G., Pandey D.P., Jaskolska M., and Gerdes K. HicA of Escherichia coli defines a novel family of translation-independent mRNA interferases in bacteria and archaea. J Bacteriol 191 (2009) 1191-1199
-
(2009)
J Bacteriol
, vol.191
, pp. 1191-1199
-
-
Jorgensen, M.G.1
Pandey, D.P.2
Jaskolska, M.3
Gerdes, K.4
-
30
-
-
0036067108
-
Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins
-
Pedersen K., Christensen S.K., and Gerdes K. Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins. Mol Microbiol 45 (2002) 501-510
-
(2002)
Mol Microbiol
, vol.45
, pp. 501-510
-
-
Pedersen, K.1
Christensen, S.K.2
Gerdes, K.3
-
31
-
-
0035108209
-
Programmed cell death in Escherichia coli: some antibiotics can trigger mazEF lethality
-
Sat B., Hazan R., Fisher T., Khaner H., Glaser G., and Engelberg-Kulka H. Programmed cell death in Escherichia coli: some antibiotics can trigger mazEF lethality. J Bacteriol 183 (2001) 2041-2045
-
(2001)
J Bacteriol
, vol.183
, pp. 2041-2045
-
-
Sat, B.1
Hazan, R.2
Fisher, T.3
Khaner, H.4
Glaser, G.5
Engelberg-Kulka, H.6
-
32
-
-
34247103448
-
The tmRNA system for translational surveillance and ribosome rescue
-
Moore S.D., and Sauer R.T. The tmRNA system for translational surveillance and ribosome rescue. Annu Rev Biochem 76 (2007) 101-124
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 101-124
-
-
Moore, S.D.1
Sauer, R.T.2
-
33
-
-
0033977388
-
Isolation of Neisseria gonorrhoeae mutants that show enhanced trafficking across polarized T84 epithelial monolayers
-
Hopper S., Wilbur J.S., Vasquez B.L., Larson J., Clary S., Mehr I.J., Seifert H.S., and So M. Isolation of Neisseria gonorrhoeae mutants that show enhanced trafficking across polarized T84 epithelial monolayers. Infect Immun 68 (2000) 896-905
-
(2000)
Infect Immun
, vol.68
, pp. 896-905
-
-
Hopper, S.1
Wilbur, J.S.2
Vasquez, B.L.3
Larson, J.4
Clary, S.5
Mehr, I.J.6
Seifert, H.S.7
So, M.8
-
34
-
-
33846011436
-
Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs
-
Mattison K., Wilbur J.S., So M., and Brennan R.G. Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs. J Biol Chem 281 (2006) 37942-37951
-
(2006)
J Biol Chem
, vol.281
, pp. 37942-37951
-
-
Mattison, K.1
Wilbur, J.S.2
So, M.3
Brennan, R.G.4
-
35
-
-
0034991650
-
Mutation in the ntrR gene, a member of the vap gene family, increases the symbiotic efficiency of Sinorhizobium meliloti
-
Olah B., Kiss E., Gyorgypal Z., Borzi J., Cinege G., Csanadi G., Batut J., Kondorosi A., and Dusha I. Mutation in the ntrR gene, a member of the vap gene family, increases the symbiotic efficiency of Sinorhizobium meliloti. Mol Plant Microbe Interact 14 (2001) 887-894
-
(2001)
Mol Plant Microbe Interact
, vol.14
, pp. 887-894
-
-
Olah, B.1
Kiss, E.2
Gyorgypal, Z.3
Borzi, J.4
Cinege, G.5
Csanadi, G.6
Batut, J.7
Kondorosi, A.8
Dusha, I.9
-
36
-
-
8644265008
-
Wide-range transcriptional modulating effect of ntrR under microaerobiosis in Sinorhizobium meliloti
-
Puskas L.G., Nagy Z.B., Kelemen J.Z., Ruberg S., Bodogai M., Becker A., and Dusha I. Wide-range transcriptional modulating effect of ntrR under microaerobiosis in Sinorhizobium meliloti. Mol Genet Genomics 272 (2004) 275-289
-
(2004)
Mol Genet Genomics
, vol.272
, pp. 275-289
-
-
Puskas, L.G.1
Nagy, Z.B.2
Kelemen, J.Z.3
Ruberg, S.4
Bodogai, M.5
Becker, A.6
Dusha, I.7
-
37
-
-
33845607284
-
Persister cells, dormancy and infectious disease
-
Lewis K. Persister cells, dormancy and infectious disease. Nat Rev Microbiol 5 (2007) 48-56
-
(2007)
Nat Rev Microbiol
, vol.5
, pp. 48-56
-
-
Lewis, K.1
-
38
-
-
66749179869
-
The importance of being persistent: heterogeneity of bacterial populations under antibiotic stress
-
Gefen O., and Balaban N.Q. The importance of being persistent: heterogeneity of bacterial populations under antibiotic stress. FEMS Microbiol Rev 33 (2009) 704-717
-
(2009)
FEMS Microbiol Rev
, vol.33
, pp. 704-717
-
-
Gefen, O.1
Balaban, N.Q.2
-
39
-
-
43149116340
-
Single-cell protein induction dynamics reveals a period of vulnerability to antibiotics in persister bacteria
-
This ingenious study uses technology developed previously (see ref. [48]) to observe individual bacterial cell pedigrees by isolation and growth in microgrooves. Macromolecular synthesis of individual type 1 persister cells was detected by fluorescence using a tetracycline promoter driving mCherry fluorescent reporter. The authors unexpectedly find that persister cells are metabolically active for 1.5 h after stationary phase exit, and then become dormant. This is the first indication that there is a defined persistence program.
-
Gefen O., Gabay C., Mumcuoglu M., Engel G., and Balaban N.Q. Single-cell protein induction dynamics reveals a period of vulnerability to antibiotics in persister bacteria. Proc Natl Acad Sci U S A 105 (2008) 6145-6149. This ingenious study uses technology developed previously (see ref. [48]) to observe individual bacterial cell pedigrees by isolation and growth in microgrooves. Macromolecular synthesis of individual type 1 persister cells was detected by fluorescence using a tetracycline promoter driving mCherry fluorescent reporter. The authors unexpectedly find that persister cells are metabolically active for 1.5 h after stationary phase exit, and then become dormant. This is the first indication that there is a defined persistence program.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 6145-6149
-
-
Gefen, O.1
Gabay, C.2
Mumcuoglu, M.3
Engel, G.4
Balaban, N.Q.5
-
40
-
-
4644343922
-
Bacterial persistence as a phenotypic switch
-
Balaban N.Q., Merrin J., Chait R., Kowalik L., and Leibler S. Bacterial persistence as a phenotypic switch. Science 305 (2004) 1622-1625
-
(2004)
Science
, vol.305
, pp. 1622-1625
-
-
Balaban, N.Q.1
Merrin, J.2
Chait, R.3
Kowalik, L.4
Leibler, S.5
-
41
-
-
0020590028
-
hipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis
-
Moyed H.S., and Bertrand K.P. hipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis. J Bacteriol 155 (1983) 768-775
-
(1983)
J Bacteriol
, vol.155
, pp. 768-775
-
-
Moyed, H.S.1
Bertrand, K.P.2
-
42
-
-
0344826574
-
Characterization of the hipA7 allele of Escherichia coli and evidence that high persistence is governed by (p)ppGpp synthesis
-
Korch S.B., Henderson T.A., and Hill T.M. Characterization of the hipA7 allele of Escherichia coli and evidence that high persistence is governed by (p)ppGpp synthesis. Mol Microbiol 50 (2003) 1199-1213
-
(2003)
Mol Microbiol
, vol.50
, pp. 1199-1213
-
-
Korch, S.B.1
Henderson, T.A.2
Hill, T.M.3
-
43
-
-
45149086183
-
Nongenetic individuality in the host-phage interaction
-
Pearl S., Gabay C., Kishony R., Oppenheim A., and Balaban N.Q. Nongenetic individuality in the host-phage interaction. PLoS Biol 6 (2008) e120
-
(2008)
PLoS Biol
, vol.6
-
-
Pearl, S.1
Gabay, C.2
Kishony, R.3
Oppenheim, A.4
Balaban, N.Q.5
-
44
-
-
42049092774
-
Clocks and switches: bacterial gene regulation by DNA adenine methylation
-
Low D.A., and Casadesus J. Clocks and switches: bacterial gene regulation by DNA adenine methylation. Curr Opin Microbiol 11 (2008) 106-112
-
(2008)
Curr Opin Microbiol
, vol.11
, pp. 106-112
-
-
Low, D.A.1
Casadesus, J.2
-
45
-
-
33747436591
-
Persisters: a distinct physiological state of E. coli
-
The authors use wild-type E. coli containing a ribosomal RNA promoter driving a short-lived green fluorescent protein to isolate "dim" cells by FACS sorting, which may represent persister cells. Gene expression analysis indicates that the "dim" cells have gene expression patterns distinct from exponential and stationary phase cells, and thus may represent a new persister state. This study provides a clever was to isolate persister cells, although it isn't clear if the "dim" cells represent a single class of persister or how these persister cells relate to class I and class II persister cells.
-
Shah D., Zhang Z., Khodursky A., Kaldalu N., Kurg K., and Lewis K. Persisters: a distinct physiological state of E. coli. BMC Microbiol 6 (2006) 53. The authors use wild-type E. coli containing a ribosomal RNA promoter driving a short-lived green fluorescent protein to isolate "dim" cells by FACS sorting, which may represent persister cells. Gene expression analysis indicates that the "dim" cells have gene expression patterns distinct from exponential and stationary phase cells, and thus may represent a new persister state. This study provides a clever was to isolate persister cells, although it isn't clear if the "dim" cells represent a single class of persister or how these persister cells relate to class I and class II persister cells.
-
(2006)
BMC Microbiol
, vol.6
, pp. 53
-
-
Shah, D.1
Zhang, Z.2
Khodursky, A.3
Kaldalu, N.4
Kurg, K.5
Lewis, K.6
-
46
-
-
36448953499
-
Senescence can explain microbial persistence
-
Klapper I., Gilbert P., Ayati B.P., Dockery J., and Stewart P.S. Senescence can explain microbial persistence. Microbiology 153 (2007) 3623-3630
-
(2007)
Microbiology
, vol.153
, pp. 3623-3630
-
-
Klapper, I.1
Gilbert, P.2
Ayati, B.P.3
Dockery, J.4
Stewart, P.S.5
-
47
-
-
13944272143
-
Aging and death in an organism that reproduces by morphologically symmetric division
-
Stewart E.J., Madden R., Paul G., and Taddei F. Aging and death in an organism that reproduces by morphologically symmetric division. PLoS Biol 3 (2005) e45
-
(2005)
PLoS Biol
, vol.3
-
-
Stewart, E.J.1
Madden, R.2
Paul, G.3
Taddei, F.4
-
48
-
-
41749107942
-
Stochasticity and cell fate
-
Losick R., and Desplan C. Stochasticity and cell fate. Science 320 (2008) 65-68
-
(2008)
Science
, vol.320
, pp. 65-68
-
-
Losick, R.1
Desplan, C.2
-
49
-
-
34547604468
-
Noise in gene expression determines cell fate in Bacillus subtilis
-
The authors of this study examine the molecular basis for the bistable expression of ComK, which controls the ability to take up DNA, called comptence, in Bacillus subtilis. The comK mRNA levels in individual cells was measured by FISH and used to develop a stochastic model including positive feedback of ComK on its own promoter. By modifying the noise in ComK level, the authors were able to show that intrinsic noise in the expression of ComK controls the bistable competence switch. This work provides a framework to think about other bistable switches, with relevance to the switch to persister cells.
-
Maamar H., Raj A., and Dubnau D. Noise in gene expression determines cell fate in Bacillus subtilis. Science 317 (2007) 526-529. The authors of this study examine the molecular basis for the bistable expression of ComK, which controls the ability to take up DNA, called comptence, in Bacillus subtilis. The comK mRNA levels in individual cells was measured by FISH and used to develop a stochastic model including positive feedback of ComK on its own promoter. By modifying the noise in ComK level, the authors were able to show that intrinsic noise in the expression of ComK controls the bistable competence switch. This work provides a framework to think about other bistable switches, with relevance to the switch to persister cells.
-
(2007)
Science
, vol.317
, pp. 526-529
-
-
Maamar, H.1
Raj, A.2
Dubnau, D.3
-
50
-
-
33846796149
-
Microbial phenotypic heterogeneity and antibiotic tolerance
-
Dhar N., and McKinney J.D. Microbial phenotypic heterogeneity and antibiotic tolerance. Curr Opin Microbiol 10 (2007) 30-38
-
(2007)
Curr Opin Microbiol
, vol.10
, pp. 30-38
-
-
Dhar, N.1
McKinney, J.D.2
|