메뉴 건너뛰기




Volumn 4, Issue 5, 2009, Pages 381-388

Essential thrombocythemia: Past and present

Author keywords

JAK2; Myeloproliferative disorders; Platelets; Thrombocythemia

Indexed keywords

JAK2 PROTEIN, HUMAN; JANUS KINASE 2;

EID: 71449101785     PISSN: 18280447     EISSN: 19709366     Source Type: Journal    
DOI: 10.1007/s11739-009-0284-x     Document Type: Review
Times cited : (25)

References (54)
  • 1
    • 34347132671 scopus 로고
    • Hemorrhagische Thrombozythamie bei vascularer Schrumpfmilz (Hemorrhagic thrombocythemia with a vascular, sclerotic spleen)
    • Epstein E, Goedel A (1934) Hemorrhagische Thrombozythamie bei vascularer Schrumpfmilz (Hemorrhagic thrombocythemia with a vascular, sclerotic spleen). Virchows Archiv Pathos Anat Histopathol 293: 233-248.
    • (1934) Virchows Archiv Pathos Anat Histopathol , vol.293 , pp. 233-248
    • Epstein, E.1    Goedel, A.2
  • 2
    • 38349055822 scopus 로고
    • Thrombocythemia: Report of three cases and review of literature
    • Fanger H, Lj CellaJr, Litchman H (1954) Thrombocythemia: report of three cases and review of literature. N Engl J Med 250: 456-461.
    • (1954) N Engl J Med , vol.250 , pp. 456-461
    • Fanger, H.1    Lj Jr., C.2    Litchman, H.3
  • 3
    • 0001439494 scopus 로고
    • Hemorrhagic thrombocythemia: A critical review
    • Gunz FW (1960) Hemorrhagic thrombocythemia: a critical review. Blood 15: 706-723.
    • (1960) Blood , vol.15 , pp. 706-723
    • Gunz, F.W.1
  • 4
    • 0000984508 scopus 로고
    • Primary hemorrhagic thrombocythemia
    • Ozer FL, Traux WE, Miesch DC et al (1960) Primary hemorrhagic thrombocythemia. Am J Med 28: 807-823.
    • (1960) Am J Med , vol.28 , pp. 807-823
    • Ozer, F.L.1    Traux, W.E.2    Miesch, D.C.3
  • 5
    • 0001639195 scopus 로고
    • Some speculation on the myeloproliferative syndromes
    • Dameshek W (1951) Some speculation on the myeloproliferative syndromes. Blood 6: 372-375.
    • (1951) Blood , vol.6 , pp. 372-375
    • Dameshek, W.1
  • 6
    • 0019818299 scopus 로고
    • Evidence that essential thrombocythemia is a clonal disorder with origin in multipotent stem cell
    • Fialkow PJ, Faguet GB, Jacobson RJ et al (1981) Evidence that essential thrombocythemia is a clonal disorder with origin in multipotent stem cell. Blood 58: 916-919.
    • (1981) Blood , vol.58 , pp. 916-919
    • Fialkow, P.J.1    Faguet, G.B.2    Jacobson, R.J.3
  • 7
    • 0022743745 scopus 로고
    • Essential thrombocythemia: Clinical and laboratory characteristics at presentation
    • Murphy S, Iland J, Rosenthal D et al (1986) Essential thrombocythemia: clinical and laboratory characteristics at presentation. Semin Hematol 23: 177-192.
    • (1986) Semin Hematol , vol.23 , pp. 177-192
    • Murphy, S.1    Iland, J.2    Rosenthal, D.3
  • 8
    • 71449111540 scopus 로고    scopus 로고
    • The world health organization (WHO) classification of the myeloid neoplasms
    • Vardiman JW, Harris NL, Brunning RD (2002) The world health organization (WHO) classification of the myeloid neoplasms. Blood 14: 2202-2292.
    • (2002) Blood , vol.14 , pp. 2202-2292
    • Vardiman, J.W.1    Harris, N.L.2    Brunning, R.D.3
  • 9
    • 33645400695 scopus 로고    scopus 로고
    • X-inactivation based clonality analysis and quantitative JAK2V617F assessment reveals a strong association between clonality and JAK2V617F in PV but not ET/MMM and identifies a subset of JAK2V617F negative ET and MMM patients with clonal hematopoiesis
    • Levine RL, Belisle C, Wadleigh M et al (2006) X-inactivation based clonality analysis and quantitative JAK2V617F assessment reveals a strong association between clonality and JAK2V617F in PV but not ET/MMM and identifies a subset of JAK2V617F negative ET and MMM patients with clonal hematopoiesis. Blood 107: 4139-4141.
    • (2006) Blood , vol.107 , pp. 4139-4141
    • Levine, R.L.1    Belisle, C.2    Wadleigh, M.3
  • 10
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine RL, Wadleigh M, Cools J et al (2005) Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 7: 387-397.
    • (2005) Cancer Cell , vol.7 , pp. 387-397
    • Levine, R.L.1    Wadleigh, M.2    Cools, J.3
  • 11
    • 20144363192 scopus 로고    scopus 로고
    • Cancer Genome Project. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter EJ, Scott LM, Campbell PJ et al (2005) Cancer Genome Project. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 365: 1054-1061.
    • (2005) Lancet , vol.365 , pp. 1054-1061
    • Baxter, E.J.1    Scott, L.M.2    Campbell, P.J.3
  • 12
    • 25844432737 scopus 로고    scopus 로고
    • Altered gene expression in myeloproliferative disorders correlates with activation of signalling by the V617F mutation of Jak2
    • Kralovics R, Teo SS, Buser AS et al (2005) Altered gene expression in myeloproliferative disorders correlates with activation of signalling by the V617F mutation of Jak2. Blood 106: 3374-3376.
    • (2005) Blood , vol.106 , pp. 3374-3376
    • Kralovics, R.1    Teo, S.S.2    Buser, A.S.3
  • 13
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal Jak2 mutation leading to constitutive signaling causes polycythemia vera
    • James C, Ugo V, Le Couedic JP et al (2005) A unique clonal Jak2 mutation leading to constitutive signaling causes polycythemia vera. Nature 434: 1144-1148.
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3
  • 14
    • 20744460045 scopus 로고    scopus 로고
    • Identification of an acquired JAK2 mutation in polycythemia vera
    • Zhao R, Xing S, Li Z et al (2005) Identification of an acquired JAK2 mutation in polycythemia vera. J Biol Chem 280: 22788-22792.
    • (2005) J Biol Chem , vol.280 , pp. 22788-22792
    • Zhao, R.1    Xing, S.2    Li, Z.3
  • 15
    • 46849091155 scopus 로고    scopus 로고
    • The genetic basis of myeloproliferative disorders
    • Skoda R (2007) The genetic basis of myeloproliferative disorders. Hematology Am Soc Hematol 2007: 1-10.
    • (2007) Hematology Am Soc Hematol , vol.2007 , pp. 1-10
    • Skoda, R.1
  • 16
    • 27744606173 scopus 로고    scopus 로고
    • JAK2 mutation in essential thrombocythaemia: Clinical associations and long-term prognostic relevance
    • Wolanskyj AP, Lasho TL, Schawager SM et al (2005) JAK2 mutation in essential thrombocythaemia: clinical associations and long-term prognostic relevance. Br J Haematol 131: 208-213.
    • (2005) Br J Haematol , vol.131 , pp. 208-213
    • Wolanskyj, A.P.1    Lasho, T.L.2    Schawager, S.M.3
  • 17
    • 28244442441 scopus 로고    scopus 로고
    • Definition of subtypes of essential thrombocythemia and relation to polycythemia vera based on Jak2 V617F mutation status: A prospective study
    • Campbell PJ, Scott LM, Buck G et al (2005) Definition of subtypes of essential thrombocythemia and relation to polycythemia vera based on Jak2 V617F mutation status: a prospective study. Lancet 366: 1945-1953.
    • (2005) Lancet , vol.366 , pp. 1945-1953
    • Campbell, P.J.1    Scott, L.M.2    Buck, G.3
  • 18
    • 33646494194 scopus 로고    scopus 로고
    • Epidemiology of the myeloproliferative disorders polycythemia vera and essential thrombocythemia
    • Johansson P (2006) Epidemiology of the myeloproliferative disorders polycythemia vera and essential thrombocythemia. Semin Thromb Hemostas 32: 171-173.
    • (2006) Semin Thromb Hemostas , vol.32 , pp. 171-173
    • Johansson, P.1
  • 19
    • 33751161677 scopus 로고    scopus 로고
    • Pediatric patients with essential thrombocythemia are mostly polyclonal and V617FJAK2 negative
    • Randi ML, Putti MC, Scapin M et al (2007) Pediatric patients with essential thrombocythemia are mostly polyclonal and V617FJAK2 negative. Blood 108: 3600-3602.
    • (2007) Blood , vol.108 , pp. 3600-3602
    • Randi, M.L.1    Putti, M.C.2    Scapin, M.3
  • 20
    • 34548042964 scopus 로고    scopus 로고
    • Proposals and rationale of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia and primary myelofibrosis: Recommendations from an ad hoc international expert panel
    • Tefferi A, Thiele J, Orazi A et al (2007) Proposals and rationale of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia and primary myelofibrosis: recommendations from an ad hoc international expert panel. Blood 110: 1092-1097.
    • (2007) Blood , vol.110 , pp. 1092-1097
    • Tefferi, A.1    Thiele, J.2    Orazi, A.3
  • 21
    • 0038014047 scopus 로고    scopus 로고
    • Chronic myeloproliferative disorders with thrombocythemia: A comparative study of two classification systems (PVSG, WHO) on 839 patients
    • Thiele J, Kvasnicka HM (2003) Chronic myeloproliferative disorders with thrombocythemia: a comparative study of two classification systems (PVSG, WHO) on 839 patients. Ann Hematol 82: 148-152.
    • (2003) Ann Hematol , vol.82 , pp. 148-152
    • Thiele, J.1    Kvasnicka, H.M.2
  • 22
    • 38049188368 scopus 로고    scopus 로고
    • Bone marrow pathology in essential thrombocythemia: Intra-observer reliability and utility for identifying disease subtypes
    • Wilkins BS, Erber WN, Bareford D et al (2007) Bone marrow pathology in essential thrombocythemia: intra-observer reliability and utility for identifying disease subtypes. Blood 111: 60-70.
    • (2007) Blood , vol.111 , pp. 60-70
    • Wilkins, B.S.1    Erber, W.N.2    Bareford, D.3
  • 23
    • 13444256042 scopus 로고    scopus 로고
    • Thrombosis and hemorrhage in polycythemia vera and essential thrombocythemia
    • Elliott MA, Tefferi A (2005) Thrombosis and hemorrhage in polycythemia vera and essential thrombocythemia. Br J Haematol 128: 275-290.
    • (2005) Br J Haematol , vol.128 , pp. 275-290
    • Elliott, M.A.1    Tefferi, A.2
  • 24
    • 43949103121 scopus 로고    scopus 로고
    • Life expectancy and prognostic factors in the classic BCR/ABL-negative myeloproliferative disorders
    • Cervantes F, Passamonti F, Barosi G (2008) Life expectancy and prognostic factors in the classic BCR/ABL-negative myeloproliferative disorders. Leukemia 22: 905-914.
    • (2008) Leukemia , vol.22 , pp. 905-914
    • Cervantes, F.1    Passamonti, F.2    Barosi, G.3
  • 25
    • 84910511048 scopus 로고
    • Platelet aggregation and thrombopheresis in thrombocythemia
    • Fabris F, Randi M, Casonato A et al (1980) Platelet aggregation and thrombopheresis in thrombocythemia. Thromb Haemostas 4: 169.
    • (1980) Thromb Haemostas , vol.4 , pp. 169
    • Fabris, F.1    Randi, M.2    Casonato, A.3
  • 26
    • 33947262701 scopus 로고    scopus 로고
    • Leucocytosis is a risk factor for thrombosis in essential thrombocythemia: Interaction with treatment, standard risk factor and JAK2 mutation status
    • Carobbio A, Finazzi G, Guerini V et al (2007) Leucocytosis is a risk factor for thrombosis in essential thrombocythemia: interaction with treatment, standard risk factor and JAK2 mutation status. Blood 109: 2310-2313.
    • (2007) Blood , vol.109 , pp. 2310-2313
    • Carobbio, A.1    Finazzi, G.2    Guerini, V.3
  • 27
    • 0034672149 scopus 로고    scopus 로고
    • Polymorphonuclear leucocytes activation and hemostasis in patients with essential thrombocythemia and polycythemia vera
    • Falanga A, Marchetti M, Evangelista V et al (2000) Polymorphonuclear leucocytes activation and hemostasis in patients with essential thrombocythemia and polycythemia vera. Blood 96: 4261-4266.
    • (2000) Blood , vol.96 , pp. 4261-4266
    • Falanga, A.1    Marchetti, M.2    Evangelista, V.3
  • 28
    • 54049086618 scopus 로고    scopus 로고
    • Thrombocytosis and leukocytosis interaction in vascular complications of essential thrombocythemia
    • Carobbio A, Finazzi G, Antonioli E et al (2008) Thrombocytosis and leukocytosis interaction in vascular complications of essential thrombocythemia. Blood 112: 3135-3137.
    • (2008) Blood , vol.112 , pp. 3135-3137
    • Carobbio, A.1    Finazzi, G.2    Antonioli, E.3
  • 29
    • 21444434751 scopus 로고    scopus 로고
    • Hydroxyurea compared with anagrelide in high risk essential thrombocythemia
    • Harrison CN, Campbell RJ, Buck G et al (2005) Hydroxyurea compared with anagrelide in high risk essential thrombocythemia. N Engl J Med 353: 33-45.
    • (2005) N Engl J Med , vol.353 , pp. 33-45
    • Harrison, C.N.1    Campbell, R.J.2    Buck, G.3
  • 30
    • 34547953018 scopus 로고    scopus 로고
    • Clinical profile of homozygous JAK2 617V>F mutation in patients with polycythemia vera and essential thrombocythemia
    • Vannucchi A, AM, Antonioli E, Guglielmelli P et al (2007) Clinical profile of homozygous JAK2 617V>F mutation in patients with polycythemia vera and essential thrombocythemia. Blood 110: 840-846.
    • (2007) Blood , vol.110 , pp. 840-846
    • Vannucchi, A.A.M.1    Antonioli, E.2    Guglielmelli, P.3
  • 31
    • 71449107538 scopus 로고    scopus 로고
    • Practice guidelines for the therapy of essential thrombocythemia
    • Barbui T, Barosi G, Grossi A et al (2004) Practice guidelines for the therapy of essential thrombocythemia. Haematologica 89: 15-232.
    • (2004) Haematologica , vol.89 , pp. 15-232
    • Barbui, T.1    Barosi, G.2    Grossi, A.3
  • 32
    • 0025213422 scopus 로고
    • Incidence and risk factors for thrombotic complications in a historical cohort of 100 patients with essential thrombocythemia
    • Cortelazzo S, Viero P, Finazzi G et al (1990) Incidence and risk factors for thrombotic complications in a historical cohort of 100 patients with essential thrombocythemia. J Clin Oncol 8: 556-562.
    • (1990) J Clin Oncol , vol.8 , pp. 556-562
    • Cortelazzo, S.1    Viero, P.2    Finazzi, G.3
  • 33
    • 46749132374 scopus 로고    scopus 로고
    • The impact of Jak2 and MPL mutations on diagnosis and prognosis of splanchnic vein thrombosis. A report on 241 cases
    • Kiladijan JJ, Cervantes F, Leebeek FWG et al (2008) The impact of Jak2 and MPL mutations on diagnosis and prognosis of splanchnic vein thrombosis. A report on 241 cases. Blood 111: 4922-4929.
    • (2008) Blood , vol.111 , pp. 4922-4929
    • Kiladijan, J.J.1    Cervantes, F.2    Leebeek, F.W.G.3
  • 34
    • 0002374055 scopus 로고
    • Superior sagittal sinus thrombosis in 5 patients with essential thrombocythemia: A possible disease variant
    • Randi ML, Rossi C, Barbone E et al (1994) Superior sagittal sinus thrombosis in 5 patients with essential thrombocythemia: a possible disease variant. Rev Iberoam Tromb Hemostasia 7: 76-78.
    • (1994) Rev Iberoam Tromb Hemostasia , vol.7 , pp. 76-78
    • Randi, M.L.1    Rossi, C.2    Barbone, E.3
  • 35
    • 0035670365 scopus 로고    scopus 로고
    • Acquired von Willebrand syndrome: An important bleeding complication to be considered in patients with lymphoproliferative and myeloproliferative disorders
    • Federici A, Rand JH, Mannucci PM (2001) Acquired von Willebrand syndrome: an important bleeding complication to be considered in patients with lymphoproliferative and myeloproliferative disorders. Hematol J 2: 358-362.
    • (2001) Hematol J , vol.2 , pp. 358-362
    • Federici, A.1    Rand, J.H.2    Mannucci, P.M.3
  • 36
    • 8344229870 scopus 로고    scopus 로고
    • Life expectancy and prognostic factors for survival in patients with polycythemia vera and essential thrombocythemia
    • Passamonti F, Rumi E, Pungolino E et al (2004) Life expectancy and prognostic factors for survival in patients with polycythemia vera and essential thrombocythemia. Am J Med 117: 755-761.
    • (2004) Am J Med , vol.117 , pp. 755-761
    • Passamonti, F.1    Rumi, E.2    Pungolino, E.3
  • 37
    • 0033776929 scopus 로고    scopus 로고
    • Incidence of essential thrombocythemia in children
    • Hasle H (2000) Incidence of essential thrombocythemia in children. Br J Haematol 110: 751.
    • (2000) Br J Haematol , vol.110 , pp. 751
    • Hasle, H.1
  • 38
    • 0033982423 scopus 로고    scopus 로고
    • Features of essential thrombocythemia in childhood: Study of five children
    • Randi ML, Putti MC, Fabris F (2000) Features of essential thrombocythemia in childhood: study of five children. Br J Haematol 108: 86-89.
    • (2000) Br J Haematol , vol.108 , pp. 86-89
    • Randi, M.L.1    Putti, M.C.2    Fabris, F.3
  • 40
    • 33751197539 scopus 로고    scopus 로고
    • Normal thrombopoietin and its receptor (c-mpl) genes in children with essential thrombocythemia
    • Randi ML, Putti MC, Pacquola E (2004) Normal thrombopoietin and its receptor (c-mpl) genes in children with essential thrombocythemia. Pediatr Blood Cancer 43: 1-4.
    • (2004) Pediatr Blood Cancer , vol.43 , pp. 1-4
    • Randi, M.L.1    Putti, M.C.2    Pacquola, E.3
  • 41
    • 2542556019 scopus 로고    scopus 로고
    • Essential thrombocythemia in children: Is a treatment needed?
    • Randi ML, Putti MC (2004) Essential thrombocythemia in children: is a treatment needed? Exp Opin Pharmacother 5: 1009-1014.
    • (2004) Exp Opin Pharmacother , vol.5 , pp. 1009-1014
    • Randi, M.L.1    Putti, M.C.2
  • 42
    • 34547122759 scopus 로고    scopus 로고
    • Increased risk of pregnancy complications in patients with essential thrombocythemia carrying the Jak2 (617V>F) mutation
    • Passamonti F, Ml Randi, Rumi E et al (2007) Increased risk of pregnancy complications in patients with essential thrombocythemia carrying the Jak2 (617V>F) mutation. Blood 110: 485-489.
    • (2007) Blood , vol.110 , pp. 485-489
    • Passamonti, F.1    Ml, R.2    Rumi, E.3
  • 43
    • 24944520130 scopus 로고    scopus 로고
    • Essential thrombocythemia: Challenges and evidence-based management
    • Harrison C (2005) Essential thrombocythemia: challenges and evidence-based management. Br J Haematol 130: 153-165.
    • (2005) Br J Haematol , vol.130 , pp. 153-165
    • Harrison, C.1
  • 45
    • 0346727336 scopus 로고    scopus 로고
    • Efficacy and safety of low-dose aspirin in polycythemia vera
    • Landolfi R, Marchioli R, Kutti J et al (2004) Efficacy and safety of low-dose aspirin in polycythemia vera. N Engl J Med 350: 114-124.
    • (2004) N Engl J Med , vol.350 , pp. 114-124
    • Landolfi, R.1    Marchioli, R.2    Kutti, J.3
  • 46
    • 0028913012 scopus 로고
    • Hydroxyurea for patients with essential thrombocythemia and a high risk of thrombosis
    • Cortellazo S, Finazzi G, Ruggeri M et al (1995) Hydroxyurea for patients with essential thrombocythemia and a high risk of thrombosis. N Engl J Med 332: 1132-1136.
    • (1995) N Engl J Med , vol.332 , pp. 1132-1136
    • Cortellazo, S.1    Finazzi, G.2    Ruggeri, M.3
  • 47
    • 21344446125 scopus 로고    scopus 로고
    • Toxicity and side effects of hydroxyurea used for primary thrombocythemia
    • Randi ML, Ruzzon E, Tezza F (2005) Toxicity and side effects of hydroxyurea used for primary thrombocythemia. Platelets 16: 181-184.
    • (2005) Platelets , vol.16 , pp. 181-184
    • Randi, M.L.1    Ruzzon, E.2    Tezza, F.3
  • 48
    • 0033781129 scopus 로고    scopus 로고
    • Second malignancies in patients with essential thrombocythemia treated with busulphan and hydroxyurea: Long-term follow-up of a randomised clinical trial
    • Finazzi G, Ruggeri M, Rodeghiero F et al (2000) Second malignancies in patients with essential thrombocythemia treated with busulphan and hydroxyurea: long-term follow-up of a randomised clinical trial. Br J Haematol 110: 577-583.
    • (2000) Br J Haematol , vol.110 , pp. 577-583
    • Finazzi, G.1    Ruggeri, M.2    Rodeghiero, F.3
  • 49
    • 0036121982 scopus 로고    scopus 로고
    • Pipobroman is safe and effective treatment for patients with essential thrombocythemia at high risk of thrombosis
    • Passamonti F, Malabarba L, Orlandi E et al (2002) Pipobroman is safe and effective treatment for patients with essential thrombocythemia at high risk of thrombosis. Br J Haematol 116: 855-861.
    • (2002) Br J Haematol , vol.116 , pp. 855-861
    • Passamonti, F.1    Malabarba, L.2    Orlandi, E.3
  • 50
    • 0031047572 scopus 로고    scopus 로고
    • Anagrelide for control of thrombocythemia in polycythemia and other myeloproliferative disorders
    • Petitt RM, Silverstein MN, Petrone ME (1997) Anagrelide for control of thrombocythemia in polycythemia and other myeloproliferative disorders. Semin Hematol 34: 51-54.
    • (1997) Semin Hematol , vol.34 , pp. 51-54
    • Petitt, R.M.1    Silverstein, M.N.2    Petrone, M.E.3
  • 51
    • 0035865604 scopus 로고    scopus 로고
    • Long-term use of anagrelide in young patients with essential thrombocythemia
    • Storen EC, Tefferi A (2001) Long-term use of anagrelide in young patients with essential thrombocythemia. Blood 97: 863-866.
    • (2001) Blood , vol.97 , pp. 863-866
    • Storen, E.C.1    Tefferi, A.2
  • 52
    • 33846496178 scopus 로고    scopus 로고
    • A unified definition of clinical resistance/intolerance to hydroxyurea in essential thrombocythemia: Results of a consensus process by an international working group
    • Barosi G, Besses C, Birgegard G et al (2007) A unified definition of clinical resistance/intolerance to hydroxyurea in essential thrombocythemia: results of a consensus process by an international working group. Leukemia 21: 277-280.
    • (2007) Leukemia , vol.21 , pp. 277-280
    • Barosi, G.1    Besses, C.2    Birgegard, G.3
  • 53
    • 66549086134 scopus 로고    scopus 로고
    • Response criteria for essential thrombocythemia and polycythemia vera: Results of a ELN consensus conference
    • Barosi G, Birgegard G, Finazzi G et al (2009) Response criteria for essential thrombocythemia and polycythemia vera: results of a ELN consensus conference. Blood [e-pub ahead of print].
    • (2009) Blood [e-pub Ahead of Print]
    • Barosi, G.1    Birgegard, G.2    Finazzi, G.3
  • 54
    • 0037103624 scopus 로고    scopus 로고
    • Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta
    • Apperley JF, Gardembas M, Melo JV et al (2002) Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta. N Engl J Med 347: 472-480.
    • (2002) N Engl J Med , vol.347 , pp. 472-480
    • Apperley, J.F.1    Gardembas, M.2    Melo, J.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.