Cancer risk factors associated with insulin-like growth factor (IGF)-I and IGF-binding protein-3 levels in healthy women: Effect modification by menopausal status

Cancer Causes and Control

Volumn 20, Issue 10, 2009, Pages 1985-1996

  Barnes, Benjamin B E ^a   Chang Claude, Jenny ^a   Flesch Janys, Dieter ^b   Kinscherf, Ralf ^c   Schmidt, Martina ^a   Slanger, Tracy ^a   Bonaterra, Gabriel ^c   Steindorf, Karen ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c Centre for Biomedicine and Medical Technology Mannheim CBTM   (Germany)

Author keywords

Breast cancer; Insulin like growth factor I; Insulin like growth factor binding protein 3; Menopause; Risk factors

Indexed keywords

SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ADULT; AGE DISTRIBUTION; AGED; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; BREAST CANCER; BREAST DISEASE; CANCER RISK; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MENOPAUSE; OBESITY; PHYSICAL ACTIVITY; POSTMENOPAUSE; PREMENOPAUSE; PRIORITY JOURNAL; RISK FACTOR; SIGNAL TRANSDUCTION; SMOKING HABIT;

ADULT; AGED; BODY MASS INDEX; BREAST NEOPLASMS; CARCINOMA; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; EFFECT MODIFIER, EPIDEMIOLOGIC; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; MENOPAUSE; MIDDLE AGED; MOTOR ACTIVITY; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RISK FACTORS;

EID: 71349088728     PISSN: 09575243     EISSN: 15737225     Source Type: Journal    
DOI: 10.1007/s10552-009-9393-0     Document Type: Article

References (66)

1. H Yu T Rohan 2000 Role of the insulin-like growth factor family in cancer development and progression J Natl Cancer Inst 92 18 1472 1489 10.1093/jnci/92.18.1472 1:CAS:528:DC%2BD3cXntFKqsrw%3D 10995803
2. H Hartog J Wesseling HM Boezen WT van der Graaf 2007 The insulin-like growth factor 1 receptor in cancer: old focus, new future Eur J Cancer 43 13 1895 1904 10.1016/j.ejca.2007.05.021 1:CAS:528:DC%2BD2sXpsFKntbk%3D 17624760 (Pubitemid 47284866)
3. AG Renehan M Zwahlen C Minder ST O'dwyer SM Shalet M Egger 2004 Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis Lancet 363 9418 1346 1353 10.1016/S0140-6736(04)16044-3 1:CAS:528:DC%2BD2cXjtl2lsL0%3D 15110491 (Pubitemid 38529873)
4. R Shi H Yu J McLarty J Glass 2004 IGF-I and breast cancer: a meta-analysis Int J Cancer 111 3 418 423 10.1002/ijc.20233 1:CAS:528: DC%2BD2cXmtlKlsro%3D 15221971 (Pubitemid 38998824)
5. L Baglietto DR English JL Hopper HA Morris WD Tilley GG Giles 2007 Circulating insulin-like growth factor-I and binding protein-3 and the risk of breast cancer Cancer Epidemiol Biomarkers Prev 16 4 763 768 10.1158/1055-9965. EPI-06-0960 1:CAS:528:DC%2BD2sXjvV2msr0%3D 17416768 (Pubitemid 46650579)
6. S Rinaldi PH Peeters F Berrino, et al.. 2006 IGF-I, IGFBP-3 and breast cancer risk in women: the European Prospective Investigation into Cancer and Nutrition (EPIC) Endocr Relat Cancer 13 2 593 605 10.1677/erc.1.01150 1:CAS:528:DC%2BD28XntF2mtbg%3D 16728585 (Pubitemid 43886679)
7. IT Gram T Norat S Rinaldi, et al.. 2006 Body mass index, waist circumference and waist-hip ratio and serum levels of IGF-I and IGFBP-3 in European women Int J Obes (Lond) 30 11 1623 1631 10.1038/sj.ijo.0803324 1:CAS:528:DC%2BD28XhtFekt7nF (Pubitemid 44657836)
8. CM Friedenreich AE Cust 2008 Physical activity and breast cancer risk: impact of timing, type and dose of activity and population subgroup effects Br J Sports Med 42 8 636 647 10.1136/bjsm.2006.029132 1:STN:280: DC%2BD1crgtFSiug%3D%3D 18487249
9. EM Monninkhof SG Elias FA Vlems, et al.. 2007 Physical activity and breast cancer: a systematic review Epidemiology 18 1 137 157 10.1097/01.ede.0000251167.75581.98 17130685 (Pubitemid 46005918)
10. A Rundle 2005 Molecular epidemiology of physical activity and cancer Cancer Epidemiol Biomarkers Prev 14 1 227 236 15668499
11. MD Holmes MN Pollak SE Hankinson 2002 Lifestyle correlates of plasma insulin-like growth factor I and insulin-like growth factor binding protein 3 concentrations Cancer Epidemiol Biomarkers Prev 11 9 862 867 1:CAS:528:DC%2BD38XnvVSktr4%3D 12223430
12. H Yu J Berkel 1999 Do insulin-like growth factors mediate the effect of alcohol on breast cancer risk? Med Hypotheses 52 6 491 496 10.1054/mehy.1998. 0828 1:CAS:528:DyaK1MXltlOiur8%3D 10459827 (Pubitemid 29322565)
13. AG Renehan M Tyson M Egger RF Heller M Zwahlen 2008 Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies Lancet 371 9612 569 578 10.1016/S0140-6736(08)60269-X 18280327 (Pubitemid 351232031)
14. World Cancer Research/American Institute for Cancer Research (2007) Food, nutrition, physical activity, and the prevention of cancer: a global perspective.Washington. AICR, DC
15. J Chang-Claude N Eby M Kiechle G Bastert H Becher 2000 Breastfeeding and breast cancer risk by age 50 among women in Germany Cancer Causes Control 11 8 687 695 10.1023/A:1008907901087 1:STN:280:DC%2BD3crhtVGlsg%3D%3D 11065005 (Pubitemid 30799812)
16. K Steindorf M Schmidt S Kropp J Chang-Claude 2003 Case-control study of physical activity and breast cancer risk among premenopausal women in Germany Am J Epidemiol 157 2 121 130 10.1093/aje/kwf181 12522019 (Pubitemid 36077443)
17. D Flesch-Janys T Slanger E Mutschelknauss, et al.. 2008 Risk of different histological types of postmenopausal breast cancer by type and regimen of menopausal hormone therapy Int J Cancer 123 4 933 941 10.1002/ijc.23655 1:CAS:528:DC%2BD1cXovFWmu7o%3D 18506692 (Pubitemid 352032424)
18. S Bohlscheid-Thomas I Hoting H Boeing J Wahrendorf 1997 Reproducibility and relative validity of energy and macronutrient intake of a food frequency questionnaire developed for the German part of the EPIC project. European Prospective Investigation into Cancer and Nutrition Int J Epidemiol 26 Suppl 1 S71 S81 10.1093/ije/26.suppl-1.S71 9126535
19. BE Ainsworth WL Haskell MC Whitt, et al.. 2000 Compendium of physical activities: an update of activity codes and MET intensities Med Sci Sports Exerc 32 9 Suppl S498 S504 1:STN:280:DC%2BD3cvktlegsg%3D%3D 10993420
20. C Deal J Ma F Wilkin, et al.. 2001 Novel promoter polymorphism in insulin-like growth factor-binding protein-3: correlation with serum levels and interaction with known regulators J Clin Endocrinol Metab 86 3 1274 1280 10.1210/jc.86.3.1274 1:CAS:528:DC%2BD3MXitFWntLs%3D 11238520 (Pubitemid 32323016)
21. M Rohrbacher A Risch S Kropp J Chang-Claude 2005 The A(-336C) insulin-like growth factor binding protein-3 promoter polymorphism is not a modulator of breast cancer risk in Caucasian women Cancer Epidemiol Biomarkers Prev 14 1 289 290 1:CAS:528:DC%2BD2MXmsVOltA%3D%3D 15668511
22. Becher H (2005) General principles of data analysis: continuous covariables in epidemiological studies. In: Ahrens W, Pigeot I (eds) Handbook of epidemiology. Springer, Berlin, p 595
23. A Lukanova E Lundin A Zeleniuch-Jacquotte, et al.. 2004 Body mass index, circulating levels of sex-steroid hormones, IGF-I and IGF-binding protein-3: a cross-sectional study in healthy women Eur J Endocrinol 150 2 161 171 10.1530/eje.0.1500161 1:CAS:528:DC%2BD2cXitVWltbo%3D 14763914 (Pubitemid 38312809)
24. ML Slattery KB Baumgartner T Byers, et al.. 2005 Genetic, anthropometric, and lifestyle factors associated with IGF-1 and IGFBP-3 levels in Hispanic and non-Hispanic white women Cancer Causes Control 16 10 1147 1157 10.1007/s10552-005-0318-2 1:STN:280:DC%2BD2MrjslygtA%3D%3D 16215864 (Pubitemid 46179498)
25. I dos Santos Silva N Johnson B De Stavola, et al.. 2006 The insulin-like growth factor system and mammographic features in premenopausal and postmenopausal women Cancer Epidemiol Biomarkers Prev 15 3 449 455 10.1158/1055-9965.EPI-05-0555 1:CAS:528:DC%2BD28Xit1Oms74%3D 16537700
26. SI Helle D Ekse JM Holly PE Lonning 2002 The IGF-system in healthy pre- and postmenopausal women: relations to demographic variables and sex-steroids J Steroid Biochem Mol Biol 81 1 95 102 10.1016/S0960-0760(02)00052-3 1:CAS:528:DC%2BD38XlsVKgs74%3D 12127047 (Pubitemid 34790231)
27. ID Bezemer S Rinaldi L Dossus, et al.. 2005 C-peptide, IGF-I, sex-steroid hormones and adiposity: a cross-sectional study in healthy women within the European Prospective Investigation into Cancer and Nutrition (EPIC) Cancer Causes Control 16 5 561 572 10.1007/s10552-004-7472-9 15986111 (Pubitemid 40933626)
28. A Vrieling DW Voskuil HB Bueno de Mesquita, et al.. 2004 Dietary determinants of circulating insulin-like growth factor (IGF)-I and IGF binding proteins 1, -2 and -3 in women in The Netherlands Cancer Causes Control 15 8 787 796 10.1023/B:CACO.0000043429.51915.c6 15456992 (Pubitemid 39335575)
29. J Khosravi A Diamandi U Bodani N Khaja RG Krishna 2005 Pitfalls of immunoassay and sample for IGF-I: comparison of different assay methodologies using various fresh and stored serum samples Clin Biochem 38 7 659 666 10.1016/j.clinbiochem.2005.04.001 1:CAS:528:DC%2BD2MXmtFGisrs%3D 15885685 (Pubitemid 40961637)
30. SS Tworoger SA Missmer AH Eliassen RL Barbieri M Dowsett SE Hankinson 2007 Physical activity and inactivity in relation to sex hormone, prolactin, and insulin-like growth factor concentrations in premenopausal women-exercise and premenopausal hormones Cancer Causes Control 18 7 743 752 10.1007/s10552-007- 9017-5 17549594 (Pubitemid 46988242)
31. A Picardi UV Gentilucci EM Zardi, et al.. 2003 TNF-alpha and growth hormone resistance in patients with chronic liver disease J Interferon Cytokine Res 23 5 229 235 10.1089/107999003321829944 1:CAS:528:DC%2BD3sXjvF2mtr0%3D 12804065 (Pubitemid 36606455)
32. P Meier HK Seitz 2008 Age, alcohol metabolism and liver disease Curr Opin Clin Nutr Metab Care 11 1 21 26 10.1097/MCO.0b013e3282f30564 1:CAS:528:DC%2BD1cXhtlaqur4%3D 18090653 (Pubitemid 350295221)
33. P Angulo 2002 Nonalcoholic fatty liver disease N Engl J Med 346 16 1221 1231 10.1056/NEJMra011775 1:CAS:528:DC%2BD38XivVOmsrY%3D 11961152 (Pubitemid 34984585)
34. H Johansson L Baglietto A Guerrieri-Gonzaga, et al.. 2004 Factors associated with circulating levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in 740 women at risk for breast cancer Breast Cancer Res Treat 88 1 63 73 10.1007/s10549-004-0746-9 1:CAS:528:DC%2BD2cXpsF2mtrw%3D 15538047 (Pubitemid 39524446)
35. HC Jernstrom H Olsson A Borg 1997 Reduced testosterone, 17 beta-oestradiol and sexual hormone binding globulin, and increased insulin-like growth factor-1 concentrations, in healthy nulligravid women aged 19-25 years who were first and/or second degree relatives to breast cancer patients Eur J Cancer Prev 6 4 330 340 10.1097/00008469-199708000-00004 1:STN:280: DyaK1c%2FjslSnuw%3D%3D 9370095 (Pubitemid 27492117)
36. A Lukanova P Toniolo A Akhmedkhanov, et al.. 2001 A cross-sectional study of IGF-I determinants in women Eur J Cancer Prev 10 5 443 452 10.1097/00008469-200110000-00008 1:STN:280:DC%2BD3MnmvVSkug%3D%3D 11711759 (Pubitemid 33016255)
37. C Diorio J Brisson S Berube M Pollak 2008 Intact and total insulin-like growth factor-binding protein-3 (IGFBP-3) levels in relation to breast cancer risk factors: a cross-sectional study Breast Cancer Res 10 3 R42 10.1186/bcr2093 18471292
38. CF Singer M Mogg W Koestler, et al.. 2004 Insulin-like growth factor (IGF)-I and IGF-II serum concentrations in patients with benign and malignant breast lesions: free IGF-II is correlated with breast cancer size Clin Cancer Res 10(12 Pt 1) 4003 4009 10.1158/1078-0432.CCR-03-0093 (Pubitemid 38812474)
39. T Dorjgochoo SL Deming YT Gao, et al.. 2008 History of benign breast disease and risk of breast cancer among women in China: a case-control study Cancer Causes Control 19 8 819 828 10.1007/s10552-008-9145-6 18347922
40. JA Lavigne DJ Baer HH Wimbrow, et al.. 2005 Effects of alcohol on insulin-like growth factor I and insulin-like growth factor binding protein 3 in postmenopausal women Am J Clin Nutr 81 2 503 507 1:CAS:528:DC%2BD2MXhsFensbk%3D 15699241
41. JA Lavigne HH Wimbrow BA Clevidence, et al.. 2004 Effects of alcohol and menstrual cycle on insulin-like growth factor-I and insulin-like growth factor binding protein-3 Cancer Epidemiol Biomarkers Prev 13 12 2264 2267 1:CAS:528:DC%2BD2cXhtVOjsLnF 15598790
42. E Garcia-Valdecasas-Campelo E Gonzalez-Reimers F Santolaria-Fernandez, et al.. 2006 Serum osteoprotegerin and RANKL levels in chronic alcoholic liver disease Alcohol Alcohol 41 3 261 266 1:CAS:528:DC%2BD28XjvF2ku74%3D 16476762
43. N Hamajima K Hirose K Tajima, et al.. 2002 Alcohol, tobacco and breast cancer-collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease Br J Cancer 87 11 1234 1245 10.1038/sj.bjc.6600596 12439712 (Pubitemid 36009128)
44. S Rinaldi PH Peeters ID Bezemer, et al.. 2006 Relationship of alcohol intake and sex steroid concentrations in blood in pre- and post-menopausal women: the European Prospective Investigation into Cancer and Nutrition Cancer Causes Control 17 8 1033 1043 10.1007/s10552-006-0041-7 1:STN:280: DC%2BD28rgs1GisA%3D%3D 16933054 (Pubitemid 44290768)
45. JV Porch K Jain A Reilly, et al.. 1997 Aging, physical activity, insulin-like growth factor I, and body composition in Guatemalan women Am J Clin Nutr 66 4 874 879 1:STN:280:DyaK2svmtlylsA%3D%3D 9322563
46. S Chang X Wu H Yu MR Spitz 2002 Plasma concentrations of insulin-like growth factors among healthy adult men and postmenopausal women: associations with body composition, lifestyle, and reproductive factors Cancer Epidemiol Biomarkers Prev 11 8 758 766 1:CAS:528:DC%2BD38XmvVaqsb8%3D 12163330
47. K DeLellis S Rinaldi RJ Kaaks LN Kolonel B Henderson ML Le 2004 Dietary and lifestyle correlates of plasma insulin-like growth factor-I (IGF-I) and IGF binding protein-3 (IGFBP-3): the multiethnic cohort Cancer Epidemiol Biomarkers Prev 13 9 1444 1451 1:CAS:528:DC%2BD2cXntFCks7c%3D 15342444
48. A Figueroa SB Going LA Milliken, et al.. 2003 Effects of exercise training and hormone replacement therapy on lean and fat mass in postmenopausal women J Gerontol A Biol Sci Med Sci 58 3 266 270 12634293
49. A McTiernan B Sorensen Y Yasui, et al.. 2005 No effect of exercise on insulin-like growth factor 1 and insulin-like growth factor binding protein 3 in postmenopausal women: a 12-month randomized clinical trial Cancer Epidemiol Biomarkers Prev 14 4 1020 1021 10.1158/1055-9965.EPI-04-0834 1:CAS:528:DC%2BD2MXjtFSktLs%3D 15824183 (Pubitemid 40478576)
50. ZR Haydar MR Blackman JD Tobin JG Wright JL Fleg 2000 The relationship between aerobic exercise capacity and circulating IGF-1 levels in healthy men and women J Am Geriatr Soc 48 2 139 145 1:CAS:528:DC%2BD3cXhsFahs7c%3D 10682942
51. LM Morimoto PA Newcomb E White J Bigler JD Potter 2005 Variation in plasma insulin-like growth factor-1 and insulin-like growth factor binding protein-3: personal and lifestyle factors (United States) Cancer Causes Control 16 8 917 927 10.1007/s10552-005-2702-3 16132801 (Pubitemid 41191417)
52. MS Sandhu AH Heald JM Gibson JK Cruickshank DB Dunger NJ Wareham 2002 Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study Lancet 359 9319 1740 1745 10.1016/S0140-6736(02)08655-5 1:CAS:528:DC%2BD38XktFKjtr8%3D 12049864 (Pubitemid 34607089)
53. F Xue KB Michels 2007 Diabetes, metabolic syndrome, and breast cancer: a review of the current evidence Am J Clin Nutr 86 3 s823 s835 18265476
54. M Sherlock AA Toogood 2007 Aging and the growth hormone/insulin like growth factor-I axis Pituitary 10 2 189 203 10.1007/s11102-007-0039-5 1:CAS:528:DC%2BD2sXlslCktLs%3D 17492509 (Pubitemid 46863733)
55. T Yamaguchi M Kanatani M Yamauchi, et al.. 2006 Serum levels of insulin-like growth factor (IGF); IGF-binding proteins-3, -4, and -5; and their relationships to bone mineral density and the risk of vertebral fractures in postmenopausal women Calcif Tissue Int 78 1 18 24 10.1007/s00223-005-0163-z 1:CAS:528:DC%2BD28XkvFOjsw%3D%3D 16397738 (Pubitemid 43107288)
56. PH Lahmann K Hoffmann N Allen, et al.. 2004 Body size and breast cancer risk: findings from the European Prospective Investigation into Cancer And Nutrition (EPIC) Int J Cancer 111 5 762 771 10.1002/ijc.20315 1:CAS:528:DC%2BD2cXmvVenu7w%3D 15252848 (Pubitemid 39062901)
57. ES Schernhammer SS Tworoger AH Eliassen, et al.. 2007 Body shape throughout life and correlations with IGFs and GH Endocr Relat Cancer 14 3 721 732 10.1677/ERC-06-0080 1:CAS:528:DC%2BD2sXhsVSitr7P 17914102 (Pubitemid 350074061)
58. M Scacchi AI Pincelli F Cavagnini 1999 Growth hormone in obesity Int J Obes Relat Metab Disord 23 3 260 271 10.1038/sj.ijo.0800807 1:CAS:528: DyaK1MXitFGms74%3D 10193871
59. NE Allen PN Appleby R Kaaks S Rinaldi GK Davey TJ Key 2003 Lifestyle determinants of serum insulin-like growth-factor-I (IGF-I), C-peptide and hormone binding protein levels in British women Cancer Causes Control 14 1 65 74 10.1023/A:1022518321634 12708727 (Pubitemid 36403271)
60. NM Probst-Hensch H Wang VH Goh A Seow HP Lee MC Yu 2003 Determinants of circulating insulin-like growth factor I and insulin-like growth factor binding protein 3 concentrations in a cohort of Singapore men and women Cancer Epidemiol Biomarkers Prev 12 8 739 746 1:CAS:528:DC%2BD3sXmt1elsrY%3D 12917205
61. N Baibas C Bamia E Vassilopoulou J Sdrolias A Trichopoulou D Trichopoulos 2003 Dietary and lifestyle factors in relation to plasma insulin-like growth factor I in a general population sample Eur J Cancer Prev 12 3 229 234 10.1097/00008469-200306000-00010 1:STN:280:DC%2BD3s3kslCrug%3D%3D 12771562 (Pubitemid 36683759)
62. H Jernstrom C Deal F Wilkin, et al.. 2001 Genetic and nongenetic factors associated with variation of plasma levels of insulin-like growth factor-I and insulin-like growth factor-binding protein-3 in healthy premenopausal women Cancer Epidemiol Biomarkers Prev 10 4 377 384 1:CAS:528:DC%2BD3MXjvVaqu7k%3D 11319179
63. K Landin-Wilhelmsen L Wilhelmsen G Lappas, et al.. 1994 Serum insulin-like growth factor I in a random population sample of men and women: relation to age, sex, smoking habits, coffee consumption and physical activity, blood pressure and concentrations of plasma lipids, fibrinogen, parathyroid hormone and osteocalcin Clin Endocrinol (Oxf) 41 3 351 357 10.1111/j.1365-2265. 1994.tb02556.x 1:CAS:528:DyaK2cXmsVOisrc%3D
64. K Landin-Wilhelmsen PA Lundberg G Lappas L Wilhelmsen 2004 Insulin-like growth factor I levels in healthy adults Horm Res 62 Suppl 1 8 16 10.1159/000080753 1:CAS:528:DC%2BD2MXitFOlt70%3D 15761227 (Pubitemid 40532959)
65. AG Renehan WS Atkin ST O'dwyer SM Shalet 2004 The effect of cigarette smoking use and cessation on serum insulin-like growth factors Br J Cancer 91 8 1525 1531 10.1038/sj.bjc.6602150 1:CAS:528:DC%2BD2cXotlCktb4%3D 15354219 (Pubitemid 39486358)
66. CB Ambrosone S Kropp J Yang S Yao PG Shields J Chang-Claude 2008 Cigarette smoking, N-acetyltransferase 2 genotypes, and breast cancer risk: pooled analysis and meta-analysis Cancer Epidemiol Biomarkers Prev 17 1 15 26 10.1158/1055-9965.EPI-07-0598 1:CAS:528:DC%2BD1cXmt12itQ%3D%3D 18187392 (Pubitemid 351196269)