Neonatal exposure to parathion alters lipid metabolism in adulthood: Interactions with dietary fat intake and implications for neurodevelopmental deficits

Brain Research Bulletin

Volumn 81, Issue 1, 2010, Pages 85-91

  Lassiter, T Leon ^a   Ryde, Ian T ^a   Levin, Edward D ^a   Seidler, Frederic J ^a   Slotkin, Theodore A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Adipokines; Adiponectin; Developmental toxicity; Diabetes; Dietary fat intake; Leptin; Lipid metabolism; Obesity; Organophosphate insecticides; Oxidative stress; Parathion; Tumor necrosis factor

Indexed keywords

ADIPONECTIN; LEPTIN; PARATHION; TUMOR NECROSIS FACTOR ALPHA;

ADIPOSE TISSUE; ADULTHOOD; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; FAT INTAKE; FEMALE; LIPID DIET; LIPID METABOLISM; LIPID PEROXIDATION; MALE; NEUROTOXICITY; NEWBORN; NONHUMAN; ORGAN DISTRIBUTION; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT;

ADIPONECTIN; ADIPOSE TISSUE; AGING; ANIMALS; ANIMALS, NEWBORN; BODY WEIGHT; BRAIN; CHOLINESTERASE INHIBITORS; DIET; DIETARY FATS; EATING; FEMALE; LEPTIN; LIPID METABOLISM; MALE; PARATHION; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 71349084068     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2009.07.002     Document Type: Article

References (49)

1. Abdollahi M., Donyavi M., Pournourmohammadi S., and Saadat M. Hyperglycemia associated with increased hepatic glycogen phosphorylase and phosphoenolpyruvate carboxykinase in rats following subchronic exposure to malathion. Comp. Biochem. Physiol. Toxicol. Pharmacol. 137 (2004) 343-347
2. Ahima R.S. Adipose tissue as an endocrine organ. Obesity 14 (2006) 242S-249S
3. Alexandraki K., Piperi C., Kalofoutis C., Singh J., Alaveras A., and Kalofoutis A. Inflammatory process in type 2 diabetes: the role of cytokines. Ann. N. Y. Acad. Sci. 1084 (2006) 89-117
4. Beltowski J., Wojcicka G., Gorny D., and Marciniak A. The effect of dietary-induced obesity on lipid peroxidation, antioxidant enzymes and total plasma antioxidant capacity. J. Physiol. Pharmacol. 51 (2000) 883-896
5. Casida J.E., and Quistad G.B. Organophosphate toxicology: safety aspects of nonacetylcholinesterase secondary targets. Chem. Res. Toxicol. 17 (2004) 983-998
6. Clandinin M.T., Foot M., and Robson L. Plasma membrane: can its structure and function be modulated by dietary fat?. Comp. Biochem. Physiol. B 76 (1983) 335-339
7. Clegg D.J., van M., and Gemert. Determination of the reference dose for chlorpyrifos: proceedings of an expert panel. J. Toxicol. Environ. Health 2 (1999) 211-255
8. Curl C.L., Fenske R.A., Kissel J.C., Shirai J.H., Moate T.F., Griffith W., Coronado G., and Thompson B. Evaluation of take-home organophosphorus pesticide exposure among agricultural workers and their children. Environ. Health Perspect. 110 (2002) A787-A792
9. D'Aquino M., Benedetti P.C., Di Felice M., Gentili V., Tomassi G., Maiorino M., and Ursini F. Effect of fish oil and coconut oil on antioxidant defence system and lipid peroxidation in rat liver. Free Radic. Res. Commun. 12 (1991) 147-152
10. Eskenazi B., Marks A.R., Bradman A., Harley K., Barr D.B., Johnson C., Morga N., and Jewell N.P. Organophosphate pesticide exposure and neurodevelopment in young Mexican-American children. Environ. Health Perspect. 115 (2007) 792-798
11. Fenske R.A., Kissel J.C., Lu C., Kalman D.A., Simcox N.J., Allen E.H., and Keifer M.C. Biological based pesticide dose estimates for children in an agricultural community. Environ. Health Perspect. 108 (2000) 515-520
12. Geiser F. Influence of polyunsaturated and saturated dietary lipids on adipose tissue, brain and mitochondrial membrane fatty acid composition of a mammalian hibernator. Biochim. Biophys. Acta 1046 (1990) 159-166
13. Guan Z.Z., Yu W.F., and Nordberg A. Dual effects of nicotine on oxidative stress and neuroprotection in PC12 cells. Neurochem. Int. 43 (2003) 243-249
14. Gudbjarnason S., and Benediktsdottir V.E. Regulation of β-adrenoceptor properties and the lipid milieu in heart muscle membranes during stress. Mol. Cell. Biochem. 164 (1996) 137-143
15. Gupta R.C. Brain regional heterogeneity and toxicological mechanisms of organophosphates and carbamates. Toxicol. Mech. Meth. 14 (2004) 103-143
16. Hotamisligil G.S. Mechanisms of TNF-α-induced insulin resistance. Exp. Clin. Endocrinol. Diabetes 107 (1999) 119-125
17. Hotta K., Funahashi T., Bodkin N.L., Ortmeyer H.K., Arita Y., Hansen B.C., and Matsuzawa Y. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes 50 (2001) 1126-1133
18. Kazumi T., Kawaguchi A., Hirano T., and Yoshino G. Serum adiponectin is associated with high-density lipoprotein cholesterol, triglycerides, and low-density lipoprotein particle size in young healthy men. Metabolism 53 (2004) 589-593
19. Kelly J.F., Joseph J.A., Denisova N.A., Erat S., Mason R.P., and Roth G.S. Dissociation of striatal GTPase and dopamine release responses to muscarinic cholinergic agonists in F344 rats: influence of age and dietary manipulation. J. Neurochem. 64 (1995) 2755-2764
20. Lassiter T.L., and Brimijoin S. Rats gain excess weight after developmental exposure to the organophosphorothionate pesticide, chlorpyrifos. Neurotoxicol. Teratol. 30 (2008) 125-130
21. Lassiter T.L., Ryde I.T., MacKillop E.A., Brown K.K., Levin E.D., Seidler F.J., and Slotkin T.A. Exposure of neonatal rats to parathion elicits sex-selective reprogramming of metabolism and alters the response to a high-fat diet in adulthood. Environ. Health Perspect. 116 (2008) 1456-1462
22. Meggs W.J., and Brewer K.L. Weight gain associated with chronic exposure to chlorpyrifos in rats. J. Med. Toxicol. 3 (2007) 89-93
23. Meyer A., Seidler F.J., and Slotkin T.A. Developmental effects of chlorpyrifos extend beyond neurotoxicity: critical periods for immediate and delayed-onset effects on cardiac and hepatic cell signaling. Environ. Health Perspect. 112 (2004) 170-178
24. Molina P.E., Qian L., Schuhlein D., Naukam R., Wang H., Tracey K.J., and Abumrad N.N. CNI-1493 attenuates hemodynamic and pro-inflammatory responses to LPS. Shock 10 (1998) 329-334
25. Morgan D.P., Lin L.I., and Saikaly H.H. Morbidity and mortality in workers occupationally exposed to pesticides. Arch. Environ. Contam. Toxicol. 9 (1980) 349-382
26. Morgan M.K., Sheldon L.S., Croghan C.W., Jones P.A., Robertson G.L., Chuang J.C., Wilson N.K., and Lyu C.W. Exposures of preschool children to chlorpyrifos and its degradation product 3,5,6-trichloro-2-pyridinol in their everyday environments. J. Expos. Anal. Environ. Epidemiol. 15 (2005) 297-309
27. Nevin K.G., and Rajamohan T. Virgin coconut oil supplemented diet increases the antioxidant status in rats. Food Chem. 99 (2006) 260-266
28. Newbold R.R., Padilla-Banks E., Jefferson W.N., and Heindel J.J. Effects of endocrine disruptors on obesity. Int. J. Androl. 31 (2008) 201-208
29. Perera F.P., Rauh V., Whyatt R.M., Tang D., Tsai W.Y., Bernert J.T., Tu Y.H., Andrews H., Barr D.B., Camann D.E., Diaz D., Dietrich J., Reyes A., and Kinney P.L. A summary of recent findings on birth outcomes and developmental effects of prenatal ETS, PAH, and pesticide exposures. Neurotoxicology 26 (2005) 573-587
30. Petchuay C., Visuthismajarn P., Vitayavirasak B., Hore P., and Robson M.G. Biological monitoring of organophosphate pesticides in preschool children in an agricultural community in Thailand. Int. J. Occup. Environ. Health 12 (2006) 134-141
31. Ponsard B., Durot I., Delerive P., Oudot F., Cordelet C., Grynberg A., and Athias P. Cross-influence of membrane polyunsaturated fatty acids and hypoxia-reoxygenation on α- and β-adrenergic function of rat cardiomyocytes. Lipids 34 (1999) 457-466
32. Qiao D., Seidler F.J., and Slotkin T.A. Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifos. Toxicol. Appl. Pharmacol. 206 (2005) 17-26
33. Roegge C.S., Timofeeva O.A., Seidler F.J., Slotkin T.A., and Levin E.D. Developmental diazinon neurotoxicity in rats: later effects on emotional response. Brain Res. Bull 75 (2008) 166-172
34. Rothlein J., Rohlman D., Lasarev M., Phillips J., Muniz J., and McCauley L. Organophosphate pesticide exposure and neurobehavioral performance in agricultural and nonagricultural Hispanic workers. Environ. Health Perspect. 114 (2006) 691-696
35. Saldana T.M., Basso O., Hoppin J.A., Baird D.D., Knott C., Blair A., Alavanja M.C.R., and Sandler D.P. Pesticide exposure and self-reported gestational diabetes mellitus in the Agricultural Health Study. Diabetes Care 30 (2007) 529-534
36. Scherer P.E. Adipose tissue: from lipid storage compartment to endocrine organ. Diabetes 55 (2006) 1537-1545
37. Slotkin T.A., Bodwell B.E., Ryde I.T., Levin E.D., and Seidler F.J. Exposure of neonatal rats to parathion elicits sex-selective impairment of acetylcholine systems in brain regions during adolescence and adulthood. Environ. Health Perspect. 116 (2008) 1308-1314
38. Slotkin T.A., Brown K.K., and Seidler F.J. Developmental exposure of rats to chlorpyrifos elicits sex-selective hyperlipidemia and hyperinsulinemia in adulthood. Environ. Health Perspect. 113 (2005) 1291-1294
39. Slotkin T.A., Lassiter T.L., Ryde I.T., Wrench N., Levin E.D., and Seidler F.J. Consumption of a high-fat diet in adulthood ameliorates the effects of neonatal parathion exposure on acetylcholine systems in rat brain regions. Environ. Health Perspect. 117 (2009) 916-922
40. Slotkin T.A., Levin E.D., and Seidler F.J. Comparative developmental neurotoxicity of organophosphate insecticides: effects on brain development are separable from systemic toxicity. Environ. Health Perspect. 114 (2006) 746-751
41. Slotkin T.A., Levin E.D., and Seidler F.J. Developmental neurotoxicity of parathion: progressive effects on serotonergic systems in adolescence and adulthood. Neurotoxicol. Teratol. 31 (2009) 11-17
42. Slotkin T.A., Tate C.A., Ryde I.T., Levin E.D., and Seidler F.J. Organophosphate insecticides target the serotonergic system in developing rat brain regions: disparate effects of diazinon and parathion at doses spanning the threshold for cholinesterase inhibition. Environ. Health Perspect. 114 (2006) 1542-1546
43. T.A. Slotkin, N. Wrench, I.T. Ryde, T.L. Lassiter, E.D. Levin, F.J. Seidler, Neonatal parathion exposure disrupts serotonin and dopamine synaptic function in rat brain regions: modulation by a high-fat diet in adulthood, Neurotoxicol. Teratol., in press.
44. Snedecor G.W., and Cochran W.G. Statistical Methods (1967), Iowa State University Press, Ames, IA
45. Tataranni P.A., and Ortega E. A burning question: does an adipokine-induced activation of the immune system mediate the effect of overnutrition on type 2 diabetes?. Diabetes 54 (2005) 917-927
46. Timofeeva O.A., Sanders D., Seemann K., Yang L., Hermanson D., Regenbogen S., Agoos S., Kallepalli A., Rastogi A., Braddy D., Wells C., Perraut C., Seidler F.J., Slotkin T.A., and Levin E.D. Persistent behavioral alterations in rats neonatally exposed to low doses of the organophosphate pesticide, parathion. Brain Res. Bull. 77 (2008) 404-411
47. Trasande L., Cronk C., Durkin M., Weiss M., Schoeller D.A., Gall E.A., Hewitt J.B., Carrel A.L., Landrigan P.J., and Gillman M.W. Environment and obesity in the National Children's Study. Environ. Health Perspect. 117 (2009) 159-166
48. Whitney K.D., Seidler F.J., and Slotkin T.A. Developmental neurotoxicity of chlorpyrifos: cellular mechanisms. Toxicol. Appl. Pharmacol. 134 (1995) 53-62
49. Whyatt R.M., Camann D., Perera F.P., Rauh V.A., Tang D., Kinney P.L., Garfinkel R., Andrews H., Hoepner L., and Barr D.B. Biomarkers in assessing residential insecticide exposures during pregnancy and effects on fetal growth. Toxicol. Appl. Pharmacol. 206 (2005) 246-254