O-GlcNAc Mediated Glycosylation Down-Regulation in Mice With Cyclophosphamide Induced Cystitis

Journal of Urology

Volumn 183, Issue 1, 2010, Pages 351-356

  Chung, Seyung ^a   Kang, Dae Ook ^c   Yamzon, Jonathan ^b   Warburton, David ^a   Koh, Chester J ^c  

^a Saban Research Institute   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c Changwon National University ^*  (South Korea)

Author keywords

cystitis; glycosylation; inflammation; intercellular signaling peptides and proteins; urinary bladder

Indexed keywords

CYCLOPHOSPHAMIDE; GLYCOSIDASE; N ACETYLGLUCOSAMINE; TUMOR ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER; BLADDER INJURY; CONTROLLED STUDY; CYSTITIS; DOWN REGULATION; GLYCOSYLATION; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INJURY SEVERITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CYCLOPHOSPHAMIDE; CYSTITIS; DOWN-REGULATION; GLYCOSYLATION; MICE; N-ACETYLGLUCOSAMINYLTRANSFERASES;

EID: 71249147174     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2009.08.102     Document Type: Article

References (24)

1. Ferrero-Miliani L., Nielsen O.H., Andersen P.S., et al. Chronic inflammation: importance of NOD2 and NALP3 in interleukin-1beta generation. Clin Exp Immunol 147 (2007) 227
2. Gornik O., and Lauc G. Glycosylation of serum proteins in inflammatory diseases. Dis Markers 25 (2008) 267
3. Ohtsubo K., and Marth J.D. Glycosylation in cellular mechanisms of health and diseases. Cell 126 (2006) 855
4. Halbleib J.M., and Nelson W.J. Cadherins in development. Genes and Dev 20 (2006) 3199
5. Campbell B.J., Yu L.G., and Rhodes J.M. Altered glycosylation in inflammatory bowel disease: a possible role in cancer development. Glycoconj J 18 (2001) 851
6. Slawson C., Pidala J., and Potter R. Increased N-acetyl-beta-glucosaminidase activity in primary breast carcinomas corresponds to a decrease in N-acetylglucosamine containing proteins. Biochim Biophys Acta 1537 (2001) 147
7. Hart G.W., Housley M.P., and Slawson C. Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins. Nature 446 (2007) 1017
8. Lubas W.A., and Hanover J.A. Functional expression of O-linked GlcNAc transferase. Domain structure and substrate specificity. J Biol Chem 275 (2000) 10983
9. Shanafelt T.D., Lin T., and Geyer S.M. Pentostatin, cyclophosphamide, and rituximab regimen in older patients with chronic lymphocytic leukemia. Cancer 109 (2007) 2291
10. Ahluwalia A., Maggi C.A., Santicioli P., et al. Characterisation of the capsaicin-sensitive component of cyclophosphamide-induced inflammation in the rat urinary bladder. Br J Pharmacol 111 (1994) 1017
11. Vizzard M.A. Up-regulation of pituitary adenylate cyclase-activating polypeptide in urinary bladder pathways after chronic cystitis. J Comp Neurol 420 (2000) 335
12. Yoshimura N., and de Groat W.C. Increased excitablity of afferent neurons innervating rat urinary bladder following chronic bladder inflammation. J Neurosci 19 (1999) 4644
13. Vizzard M.A. Changes in urinary bladder neurotrophic factor mRNA and NGF protein following urinary bladder dysfunction. Exp Neurol 161 (2000) 273
14. Murray E., Malley S.E., Li-Ya Q., et al. Cyclophosphamide induced cystitis alters neurotrophin and receptor tyrosine kinase expression in pelvic ganglia and bladder. J Urol 172 (2004) 2434
15. Jezernik K., Romih R., and Mannherz H.G. Immunohistochemical detection of apoptosis, proliferation and inducible nitric oxide synthase in rat urothelium damaged by cyclophosphamide treatment. Cell Biol Int 27 (2003) 863
16. Farsund T. Cell kinetics of mouse urinary bladder epithelium. II. Changes in proliferation and nuclear DNA content during necrosis regeneration, and hyperplasia caused by a single dose of cyclophosphamide. Virchows Arch 21 (1976) 279
17. Kunze E., Köhnecke B., and Engelhardt W. Effect of the uroprotector sodium 2-mercaptoethane sulfonate (Mesna) on the proliferation of the bladder urothelium in the rat after administration of cyclophosphamide. Urol Int 39 (1984) 61
18. Zupanĉiĉ D., Jezernik K., and Vidmar G. Effect of melatonin on apoptosis, proliferation and differentiation of urothelial cells after cyclophosphamide treatment. J Pineal Res 44 (2008) 299
19. Golks A., and Guerini D. The O-linked N-acetylglucosamine modification in cellular signalling and the immune system. Protein modifications: beyond the usual suspects' review series. EMBO Rep 9 (2008) 748
20. Yang X., Zhang F., and Kudlow J.E. Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A; coupling protein O-GlcNAc transferase to transcriptional repression. Cell 110 (2002) 69
21. O'Donnell N., Zachara N.E., Hart G.W., et al. Ogt-dependent X-Chromosome linked protein glycosylation is a requisite modification in somatic cell function and embryo viability. Mol Cell Biol 24 (2004) 1680
22. Slawson C., Pidala J., and Potter R. Increased N-acetyl-b-glucosaminidase activity in primary breast carcinoma corresponds to a decrease in N-acetylglucosamine containing protein. Biochim Biophys Acta 1537 (2001) 147
23. Xing D., Feng W., Not L.G., et al. Increased protein O-GlcNAc modification inhibits inflammatory and neointimal responses to acute endoluminal arterial injury. Am J Physiol Heart Circ Physiol 295 (2008) 335
24. Dube D.H., and Bertozzi C.R. Glycans in cancer and inflammation-potential for therapeutics and diagnostics. Nat Rev Drug Discov 4 (2005) 477