Study of the essentiality of the Aspergillus fumigatus triA gene, encoding RNA triphosphatase, using the heterokaryon rescue technique and the conditional gene expression driven by the alcA and niiA promoters

Fungal Genetics and Biology

Volumn 47, Issue 1, 2010, Pages 66-79

  Monteiro, M Cândida ^a   De Lucas, J Ramón ^a  

^a UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

alcA promoter; Amphotericin B; Aspergillus fumigatus; Essential gene; Heterokaryon rescue technique; Invasive aspergillosis; niiA promoter; RNA triphosphatase; Therapeutic target; triA gene

Indexed keywords

AMPHOTERICIN B; ANTIFUNGAL AGENT; FUNGAL ENZYME; RNA TRIPHOSPHATASE; UNCLASSIFIED DRUG;

ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; ASPERGILLUS FUMIGATUS; CONTROLLED STUDY; DOWN REGULATION; DRUG TARGETING; ENZYME INHIBITION; EPSILOMETER TEST; ESSENTIAL GENE; FUNGAL GENE; FUNGAL MORPHOLOGY; FUNGAL STRAIN; FUNGUS GROWTH; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION SYSTEM; GENE IDENTIFICATION; GROWTH INHIBITION; HETEROKARYON; MYCOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; STRUCTURE ANALYSIS;

ACID ANHYDRIDE HYDROLASES; AMINO ACID SEQUENCE; ANTIFUNGAL AGENTS; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CLONING, MOLECULAR; DOWN-REGULATION; FUNGAL PROTEINS; GENE EXPRESSION; GENES, ESSENTIAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROMOTER REGIONS, GENETIC; SEQUENCE ALIGNMENT;

ASPERGILLUS FUMIGATUS; SACCHAROMYCES CEREVISIAE;

EID: 71249133591     PISSN: 10871845     EISSN: 10960937     Source Type: Journal    
DOI: 10.1016/j.fgb.2009.10.010     Document Type: Article

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