Identification of iminooxothiazolidines as secreted frizzled related protein-1 inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 22, 2009, Pages 6337-6339

  Shi, Mengxiao ^a   Stauffer, Barbara ^b   Bhat, Ramesh ^b   Billiard, Julia ^b   Ponce de Leon, Helga ^b   Seestaller Wehr, Laura ^b   Fukayama, Shoichi ^b   Mangine, Annamarie ^b   Moran, Robert ^b   Krishnamurthy, Girija ^a   Bodine, Peter ^b   Gopalsamy, Ariamala ^a  

^a WYETH RESEARCH   (United States)

^b Womens Health and Musculoskeletal Biology   (United States)

Author keywords

sFRP1 inhibitor osteoporosis

Indexed keywords

IMINOOXOTHIAZOLIDINE; PROTEIN INHIBITOR; SECRETED FRIZZLED RELATED PROTEIN 1; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOCHEMISTRY; CALVARIA; CONTROLLED STUDY; DRUG BINDING; DRUG IDENTIFICATION; DRUG SELECTIVITY; EX VIVO STUDY; HIGH THROUGHPUT SCREENING; MOUSE; NONHUMAN; OSTEOPOROSIS; STRUCTURE ACTIVITY RELATION;

CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELLS, CULTURED; FRIZZLED RECEPTORS; MOLECULAR STRUCTURE; OSTEOGENESIS; PROTEINS; RANK LIGAND;

EID: 71049184032     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.09.085     Document Type: Article

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