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Volumn 52, Issue 21, 2009, Pages 6523-6526

Mitoxantrone analogues as ligands for a stem-loop structure of tau Pre-mRNA

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA PRECURSOR; MITOXANTRONE; TAU PROTEIN;

EID: 71049175350     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9013407     Document Type: Article
Times cited : (45)

References (18)
  • 1
    • 33750705653 scopus 로고    scopus 로고
    • A century of Alzheimer's disease
    • Goedert, M.; Spillantini, M. G. A century of Alzheimer's disease. Science 2006, 314, 777-781.
    • (2006) Science , vol.314 , pp. 777-781
    • Goedert, M.1    Spillantini, M.G.2
  • 2
    • 34548036227 scopus 로고    scopus 로고
    • Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
    • Ballatore, C.; Lee, V. M.; Trojanowski, J. Q. Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nat. Rev. Neurosci. 2007, 8, 663-672.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 663-672
    • Ballatore, C.1    Lee, V.M.2    Trojanowski, J.Q.3
  • 3
    • 65249116483 scopus 로고    scopus 로고
    • Tau mutations in neurodegenerative diseases
    • Wolfe, M. S. Tau mutations in neurodegenerative diseases. J. Biol. Chem. 2009, 284, 6021-6025.
    • (2009) J. Biol. Chem. , vol.284 , pp. 6021-6025
    • Wolfe, M.S.1
  • 4
    • 0032543684 scopus 로고    scopus 로고
    • Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17
    • Hutton, M.; Lendon, C. L.; Rizzu, P.; Baker, M.; Froelich, S.; Houlden, H.; et al. Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17. Nature 1998, 393, 702-705.
    • (1998) Nature , vol.393 , pp. 702-705
    • Hutton, M.1    Lendon, C.L.2    Rizzu, P.3    Baker, M.4    Froelich, S.5    Houlden, H.6
  • 6
    • 33747634776 scopus 로고    scopus 로고
    • Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing
    • Donahue, C. P.; Muratore, C.; Wu, J. Y.; Kosik, K. S.; Wolfe, M. S. Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing. J. Biol. Chem. 2006, 281, 23302-23306.
    • (2006) J. Biol. Chem. , vol.281 , pp. 23302-23306
    • Donahue, C.P.1    Muratore, C.2    Wu, J.Y.3    Kosik, K.S.4    Wolfe, M.S.5
  • 8
    • 0034141513 scopus 로고    scopus 로고
    • Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics
    • Varani, L.; Spillantini, M. G.; Goedert, M.; Varani, G. Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics. Nucleic Acids Res. 2000, 28, 710-719. (Pubitemid 30068254)
    • (2000) Nucleic Acids Research , vol.28 , Issue.3 , pp. 710-719
    • Varani, L.1    Spillantini, M.G.2    Goedert, M.3    Varani, G.4
  • 9
    • 43149103943 scopus 로고    scopus 로고
    • Targeting RNA with small molecules
    • Thomas, J. R.; Hergenrother, P. J. Targeting RNA with small molecules. Chem. Rev. 2008, 108, 1171-1224.
    • (2008) Chem. Rev. , vol.108 , pp. 1171-1224
    • Thomas, J.R.1    Hergenrother, P.J.2
  • 10
    • 65749105061 scopus 로고    scopus 로고
    • Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone)
    • Zheng, S.; Chen, Y.; Donahue, C. P.; Wolfe, M. S.; Varani, G. Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone). Chem. Biol. 2009, 16, 557-566.
    • (2009) Chem. Biol. , vol.16 , pp. 557-566
    • Zheng, S.1    Chen, Y.2    Donahue, C.P.3    Wolfe, M.S.4    Varani, G.5
  • 12
    • 0034641682 scopus 로고    scopus 로고
    • Binding of a macrocyclic bisacridine and ametantrone to CGTACG involves similar unusual intercalation platforms
    • Yang, X.-L.; Robinson, H.; Gao, Y.-G.; Wang, A. H.-J. Binding of a macrocyclic bisacridine and ametantrone to CGTACG involves similar unusual intercalation platforms. Biochemistry 2000, 39, 10950-10957.
    • (2000) Biochemistry , vol.39 , pp. 10950-10957
    • Yang, X.-L.1    Robinson, H.2    Gao, Y.-G.3    Wang, A.H.-J.4
  • 13
    • 0023194654 scopus 로고
    • Structural modification study of mitoxantrone (DHAQ). Chloro-substituted mono- and bis[(aminoalkyl)amino]-anthraquinones
    • Zee-Cheng, R. K.; Mathew, A. E.; Xu, P. L.; Northcutt, R. V.; Cheng, C. C. Structural modification study of mitoxantrone (DHAQ). Chloro-substituted mono- and bis[(aminoalkyl)amino]-anthraquinones. J. Med. Chem. 1987, 30, 1682-1686.
    • (1987) J. Med. Chem. , vol.30 , pp. 1682-1686
    • Zee-Cheng, R.K.1    Mathew, A.E.2    Xu, P.L.3    Northcutt, R.V.4    Cheng, C.C.5
  • 14
    • 43949156512 scopus 로고
    • Synthesis of fluorine-substituted anthraquinones and aza-anthraquinones
    • Khanapure, S. P.; Han, W.; Swartling, D. J.; Biehl, E. R. Synthesis of fluorine-substituted anthraquinones and aza-anthraquinones. J. Fluorine Chem. 1994, 68, 131-134.
    • (1994) J. Fluorine Chem. , vol.68 , pp. 131-134
    • Khanapure, S.P.1    Han, W.2    Swartling, D.J.3    Biehl, E.R.4
  • 15
    • 0035805364 scopus 로고    scopus 로고
    • First, atropo-enantioselective total synthesis of the axially chiral phenylanthraquinone natural products knipholone and 6′-O-methylknipholone
    • DOI 10.1002/1521-3773(20010504)40:9<1687::AID-ANIE16870>3.0.CO;2-6
    • Bringmann, G.; Menche, D. Atropo-enantioselective total synthesis of the axially chiral phenylanthraquinone natural products knipholone and 6′-O-methylknipholone. Angew. Chem., Int. Ed. 2001, 40, 1687-1690. (Pubitemid 32441080)
    • (2001) Angewandte Chemie - International Edition , vol.40 , Issue.9 , pp. 1687-1690
    • Bringmann, G.1    Menche, D.2
  • 16
    • 37049164852 scopus 로고
    • Methyl derivatives of 1,4,5,8-tetraamino-anthraquinone
    • Hall, R. H.; Hey, D. H. Methyl derivatives of 1,4,5,8-tetraamino- anthraquinone. J. Chem. Soc. 1948, 736-740.
    • (1948) J. Chem. Soc. , pp. 736-740
    • Hall, R.H.1    Hey, D.H.2
  • 17
    • 0345329013 scopus 로고
    • Copper-assisted nucleophilic substitution of aryl halogen
    • Lindley, J. Copper-assisted nucleophilic substitution of aryl halogen. Tetrahedron 1984, 40, 1433-1456.
    • (1984) Tetrahedron , vol.40 , pp. 1433-1456
    • Lindley, J.1
  • 18
    • 0032515908 scopus 로고    scopus 로고
    • A new class of HIV-1 Tat antagonist acting through Tat-TAR inhibition
    • DOI 10.1021/bi972947s
    • Hamy, F.; Brondani, V.; Florsheimer, A.; Stark, W.; Blommers, M. J.; Klimkait, T. A new class of HIV-1 Tat antagonist acting through Tat-TAR inhibition. Biochemistry 1998, 37, 5086-5095. (Pubitemid 28176509)
    • (1998) Biochemistry , vol.37 , Issue.15 , pp. 5086-5095
    • Hamy, F.1    Brondani, V.2    Florsheimer, A.3    Stark, W.4    Blommers, M.J.J.5    Klimkait, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.