Hypoperfusion of the motor cortex associated with parkinsonism in dementia with Lewy bodies

Journal of the Neurological Sciences

Volumn 288, Issue 1-2, 2010, Pages 88-91

  Takahashi, Ryuichi ^a   Ishii, Kazunari ^b,c   Shimada, Kenichi ^b   Ohkawa, Shingo ^b   Nishimura, Yo ^a  

^a NISHI KOBE MEDICAL CENTER   (Japan)

^b Hyogo Brain and Heart Center   (Japan)

^c KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Dementia; Dementia with Lewy bodies; Parkinsonism; Primary motor cortex; Single photon emission computed tomography; Supplementary motor area; Visual hallucination

Indexed keywords

IOFETAMINE I 123;

ADULT; AGED; ARTICLE; BRAIN CIRCULATION; CLINICAL ARTICLE; CONTROLLED STUDY; DEMENTIA; FEMALE; HUMAN; LEWY BODY; MALE; MINI MENTAL STATE EXAMINATION; MOTOR CORTEX; PARKINSONISM; PERFUSION; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

AGED; AGED, 80 AND OVER; AMPHETAMINES; BRAIN MAPPING; CEREBROVASCULAR CIRCULATION; FEMALE; HALLUCINATIONS; HUMANS; LEWY BODY DISEASE; MALE; MOTOR CORTEX; NEUROPSYCHOLOGICAL TESTS; PARKINSON DISEASE; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 71049171168     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2009.09.033     Document Type: Article

References (30)

1. McKeith I.G., Dickson D.W., Lowe J., Emre M., O'Brien J.T., Feldman H., et al. Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology 65 12 (2005) 1863-1872
2. Ishii K., Imamura T., Sasaki M., Yamaji S., Sakamoto S., Kitagaki H., et al. Regional cerebral glucose metabolism in dementia with Lewy bodies and Alzheimer's disease. Neurology 51 1 (1998) 125-130
3. Higuchi M., Tashiro M., Arai H., Okamura N., Hara S., Higuchi S., et al. Glucose hypometabolism and neuropathological correlates in brains of dementia with Lewy bodies. Exp Neurol 162 2 (2000) 247-256
4. Minoshima S., Foster N.L., Sima A.A., Frey K.A., Albin R.L., and Kuhl D.E. Alzheimer's disease versus dementia with Lewy bodies: cerebral metabolic distinction with autopsy confirmation. Ann Neurol 50 3 (2001) 358-365
5. Ishii K., Hosaka K., Mori T., and Mori E. Comparison of FDG-PET and IMP-SPECT in patients with dementia with Lewy bodies. Ann Nucl Med 18 5 (2004) 447-451
6. Small G.W. Neuroimaging as a diagnostic tool in dementia with Lewy bodies. Dement Geriatr Cogn Disord 17 Suppl 1 (2004) 25-31
7. Ishii K., Yamaji S., Kitagaki H., Imamura T., Hirono N., and Mori E. Regional cerebral blood flow difference between dementia with Lewy bodies and AD. Neurology 53 2 (1999) 413-416
8. Ishii K., Soma T., Kono A.K., Sofue K., Miyamoto N., Yoshikawa T., et al. Comparison of regional brain volume and glucose metabolism between patients with mild dementia with Lewy bodies and those with mild Alzheimer's disease. J Nucl Med 48 5 (2007) 704-711
9. Kono A.K., Ishii K., Sofue K., Miyamoto N., Sakamoto S., and Mori E. Fully automatic differential diagnosis system for dementia with Lewy bodies and Alzheimer's disease using FDG-PET and 3D-SSP. Eur J Nucl Med Mol Imaging 34 9 (2007) 1490-1497
10. McKeith I.G., Galasko D., Kosaka K., Perry E.K., Dickson D.W., Hansen L.A., et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology 47 5 (1996) 1113-1124
11. Lippa C.F., Duda J.E., Grossman M., Hurtig H.I., Aarsland D., Boeve B.F., et al. DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers. Neurology 68 11 (2007) 812-819
12. Kudo Y., Horikawa Y., Noda T., Eguchi I., Watanabe Y., and Wakabayashi K. The clinical features of patients with probable dementia with Lewy bodies-report of 4 cases. Rinsho Shinkeigaku 39 4 (1999) 423-430
13. Lobotesis K., Fenwick J.D., Phipps A., Ryman A., Swann A., Ballard C., et al. Occipital hypoperfusion on SPECT in dementia with Lewy bodies but not AD. Neurology 56 5 (2001) 643-649
14. Albin R.L., Minoshima S., D'Amato C.J., Frey K.A., Kuhl D.A., and Sima A.A. Fluoro-deoxyglucose positron emission tomography in diffuse Lewy body disease. Neurology 47 2 (1996) 462-466
15. Huang C., Tang C., Feigin A., Lesser M., Ma Y., Pourfar M., et al. Changes in network activity with the progression of Parkinson's disease. Brain 130 Pt 7 (2007) 1834-1846
16. Wichmann T., and DeLong M.R. Pathophysiology of Parkinson's disease: the MPTP primate model of the human disorder. Ann NY Acad Sci 991 (2003) 199-213
17. Parent A., and Hazrati L.N. Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop. Brain Res Brain Res Rev 20 1 (1995) 91-127
18. Brooks D.J. Motor disturbance and brain functional imaging in Parkinson's disease. Eur Neurol 38 Suppl 2 (1997) 26-32
19. Thobois S., Dominey P.F., Decety J., Pollak P.P., Gregoire M.C., Le Bars P.D., et al. Motor imagery in normal subjects and in asymmetrical Parkinson's disease: a PET study. Neurology 55 7 (2000) 996-1002
20. Brooks D.J. PET and SPECT studies in Parkinson's disease. Baillieres Clin Neurol 6 1 (1997) 69-87
21. Wielepp J.P., Burgunder J.M., Pohle T., Ritter E.P., Kinser J.A., and Krauss J.K. Deactivation of thalamocortical activity is responsible for suppression of parkinsonian tremor by thalamic stimulation: a 99mTc-ECD SPECT study. Clin Neurol Neurosurg 103 4 (2001) 228-231
22. Sabatini U., Boulanouar K., Fabre N., Martin F., Carel C., Colonnese C., et al. Cortical motor reorganization in akinetic patients with Parkinson's disease: a functional MRI study. Brain 123 Pt 2 (2000) 394-403
23. Nagano-Saito A., Kato T., Arahata Y., Washimi Y., Nakamura A., Abe Y., et al. Cognitive- and motor-related regions in Parkinson's disease: FDOPA and FDG PET studies. Neuroimage 22 2 (2004) 553-561
24. Feigin A., Fukuda M., Dhawan V., Przedborski S., Jackson-Lewis V., Mentis M.J., et al. Metabolic correlates of levodopa response in Parkinson's disease. Neurology 57 11 (2001) 2083-2088
25. Hilker R., Voges J., Thiel A., Ghaemi M., Herholz K., Sturm V., et al. Deep brain stimulation of the subthalamic nucleus versus levodopa challenge in Parkinson's disease: measuring the on- and off-conditions with FDG-PET. J Neural Transm 109 10 (2002) 1257-1264
26. Haslinger B., Erhard P., Kampfe N., Boecker H., Rummeny E., Schwaiger M., et al. Event-related functional magnetic resonance imaging in Parkinson's disease before and after levodopa. Brain 124 Pt 3 (2001) 558-570
27. Rascol O., Sabatini U., Brefel C., Fabre N., Rai S., Senard J.M., et al. Cortical motor overactivation in parkinsonian patients with L-dopa-induced peak-dose dyskinesia. Brain 121 Pt 3 (1998) 527-533
28. Buhmann C., Glauche V., Sturenburg H.J., Oechsner M., Weiller C., and Buchel C. Pharmacologically modulated fMRI-cortical responsiveness to levodopa in drug-naive hemiparkinsonian patients. Brain 126 Pt 2 (2003) 451-461
29. Harding A.J., Broe G.A., and Halliday G.M. Visual hallucinations in Lewy body disease relate to Lewy bodies in the temporal lobe. Brain 125 Pt 2 (2002) 391-403
30. Perneczky R., Drzezga A., Boecker H., Forstl H., Kurz A., and Haussermann P. Cerebral metabolic dysfunction in patients with dementia with Lewy bodies and visual hallucinations. Dement Geriatr Cogn Disord 25 6 (2008) 531-538