Potential use of 2-hydroxypropyl-β-cyclodextrin for preparation of orally disintegrating tablets containing dl-α-tocopheryl acetate, an oily drug

Chemical and Pharmaceutical Bulletin

Volumn 57, Issue 11, 2009, Pages 1206-1212

  Motoyama, Keiichi ^a   Nagatomo, Kiyoshi ^a   Elazim, Soliman Osama Abd ^a   Hirayama, Fumitoshi ^b   Uekama, Kaneto ^b   Arima, Hidetoshi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b SOJO UNIVERSITY   (Japan)

Author keywords

Cyclodextrin; Disintegration time; dl tocopheryl acetate; Hardness; Molding method; Orally disintegrating tablet

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ALPHA TOCOPHEROL; BETA CYCLODEXTRIN; LACTULOSE;

ADULT; ARTICLE; COMPLEX FORMATION; DRUG SCREENING; DRUG SOLUBILITY; DRUG STABILITY; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; IN VIVO STUDY; MALE; NORMAL HUMAN; TABLET DISINTEGRATION; TABLET DISINTEGRATION TIME; TABLET HARDNESS;

ADMINISTRATION, ORAL; BETA-CYCLODEXTRINS; HUMANS; SOLUBILITY; SOLUTIONS; SURFACE TENSION; TABLETS; TOCOPHEROLS; VISCOSITY; WATER;

EID: 71049157669     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.57.1206     Document Type: Article

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