Features of intrathecal immunoglobulins in patients with multiple sclerosis

Journal of the Neurological Sciences

Volumn 288, Issue 1-2, 2010, Pages 147-150

  Di Pauli, Franziska ^a   Gredler, Viktoria ^a   Kuenz, Bettina ^a   Lutterotti, Andreas ^a   Ehling, Rainer ^a   Gneiss, Claudia ^a   Schocke, Michael ^a   Deisenhammer, Florian ^a   Reindl, Markus ^a   Berger, Thomas ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

B cells; Cerebrospinal fluid; Disease course; Immunoglobulins; Multiple sclerosis; Oligoclonal bands; Progression; Subclasses

Indexed keywords

IMMUNOGLOBULIN; IMMUNOGLOBULIN G1;

ADULT; ARTICLE; B LYMPHOCYTE; BRAIN DAMAGE; CELL POPULATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MALE; MULTIPLE SCLEROSIS; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

ADOLESCENT; ADULT; B-LYMPHOCYTES; CEREBROSPINAL FLUID; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULINS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; NERVOUS SYSTEM DISEASES; YOUNG ADULT;

EID: 71049141624     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2009.09.016     Document Type: Article

References (29)

1. Hafler D.A., Slavik J.M., Anderson D.E., O'Connor K.C., De Jager P., and Baecher-Allan C. Multiple sclerosis. Immunol Rev 204 (2005) 208-231
2. Sospedra M., and Martin R. Immunology of multiple sclerosis. Annu Rev Immunol 23 (2005) 683-747
3. Kabat E.A., Glusman M., and Knaub V. Quantitative estimation of the albumin and gamma-globulin in normal and pathological cerebrospinal fluid by immunochemical methods. Am J Med 4 (1948) 653-662
4. Obermeier B., Mentele R., Malotka J., Kellermann J., Kumpfel T., Wekerle H., et al. Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis. Nat Med 14 (2008) 688-693
5. McDonald W.I., Compston A., Edan G., Goodkin D., Hartung H.P., Lublin F.D., et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 50 (2001) 121-127
6. Cepok S., Jacobsen M., Schock S., Omer B., Jaekel S., Boddeker I., et al. Patterns of cerebrospinal fluid pathology correlate with disease progression in multiple sclerosis. Brain 124 (2001) 2169-2176
7. Lucchinetti C., Bruck W., Parisi J., Scheithauer B., Rodriguez M., and Lassmann H. Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol 47 (2000) 707-717
8. Losy J., Mehta P.D., and Wisniewski H.M. Identification of IgG subclasses' oligoclonal bands in multiple sclerosis CSF. Acta Neurol Scand 82 (1990) 4-8
9. Hulett M.D., and Hogarth P.M. Molecular basis of Fc receptor function. Adv Immunol 57 (1994) 1-127
10. Jefferis R., and Lund J. Interaction sites on human IgG-Fc for FcgammaR: current models. Immunol Lett 82 (2002) 57-65
11. Ravetch J.V., and Bolland S. IgG Fc receptors. Annu Rev Immunol 19 (2001) 275-290
12. Gerber J.S., and Mosser D.M. Stimulatory and inhibitory signals originating from the macrophage Fcgamma receptors. Microbes Infect 3 (2001) 131-139
13. Garraud O., Perraut R., Riveau G., and Nutman T.B. Class and subclass selection in parasite-specific antibody responses. Trends Parasitol 19 (2003) 300-304
14. Dhandayuthapani S., Izumi S., Anandan D., and Bhatia V.N. Specificity of IgG subclass antibodies in different clinical manifestations of leprosy. Clin Exp Immunol 88 (1992) 253-257
15. Kuenz B., Lutterotti A., Ehling R., Gneiss C., Haemmerle M., and Rainer C. Cerebrospinal fluid B cells correlate with early brain inflammation in multiple sclerosis. PLoS ONE 3 (2008) e2559
16. Polman C.H., Reingold S.C., Edan G., Filippi M., Hartung H.P., Kappos L., et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Ann Neurol 58 (2005) 840-846
17. Freedman M.S., Thompson E.J., Deisenhammer F., Giovannoni G., Grimsley G., Keir G., et al. Recommended standard of cerebrospinal fluid analysis in the diagnosis of multiple sclerosis: a consensus statement. Arch Neurol 62 (2005) 865-870
18. Greve B., Magnusson C.G., Melms A., and Weissert R. Immunoglobulin isotypes reveal a predominant role of type 1 immunity in multiple sclerosis. J Neuroimmunol 121 (2001) 120-125
19. Vartdal F., and Vandvik B. Multiple sclerosis: subclasses of intrathecally synthesized IgG and measles and varicella zoster virus IgG antibodies. Clin Exp Immunol 54 (1983) 641-647
20. Grimaldi L.M., Maimone D., Reggio A., and Raffaele R. IgG1, 3 and 4 oligoclonal bands in multiple sclerosis and other neurological diseases. Ital J Neurol Sci 7 (1986) 507-513
21. Palmer D.L., Minard B.J., and Cawley L.P. Letter: IgG subgroups in cerebrospinal fluid in multiple sclerosis. N Engl J Med 294 (1976) 447-448
22. Raknes G., Fernandes Filho J.A., Pandey J.P., Myhr K.M., Ulvestad E., Nyland H., et al. IgG allotypes and subclasses in Norwegian patients with multiple sclerosis. J Neurol Sci 175 (2000) 111-115
23. Sharief M.K., and Thompson E.J. Intrathecal immunoglobulin M synthesis in multiple sclerosis. Relationship with clinical and cerebrospinal fluid parameters. Brain 114 Pt 1A (1991) 181-195
24. Brandao C.O., Ruocco H.H., Farias A.S., Oliveira C., Cendes F., Damasceno B.P., et al. Intrathecal immunoglobulin G synthesis and brain injury by quantitative MRI in multiple sclerosis. Neuroimmunomodulation 13 (2006) 89-95
25. Milanese C., Savoiardo M., La Mantia L., Campi A., Visciani A., Salmaggi A., et al. Magnetic resonance imaging in multiple sclerosis: diagnostic value and clinical correlations. Ital J Neurol Sci 9 (1988) 127-134
26. Vrethem M., Fernlund I., Ernerudh J., and Ohman S. Prognostic value of cerebrospinal fluid IgA and IgG in multiple sclerosis. Mult Scler 10 (2004) 469-471
27. Baum K., Nehrig C., Girke W., Brau H., and Schorner W. Multiple sclerosis: relations between MRI and CT findings, cerebrospinal fluid parameters and clinical features. Clin Neurol Neurosurg 92 (1990) 49-56
28. Lambin P., Gervais A., Levy M., Defendini E., Dubarry M., Lebon P., et al. Intrathecal synthesis of IgG subclasses in multiple sclerosis and in acquired immunodeficiency syndrome (AIDS). J Neuroimmunol 35 (1991) 179-189
29. Henriksson A., Kam-Hansen S., and Link H. IgM, IgA and IgG producing cells in cerebrospinal fluid and peripheral blood in multiple sclerosis. Clin Exp Immunol 62 1 (1985) 176-184 PMID: 4064372