Protective effects of melatonin against the damages of neuroendocrine- immune induced by lipopolysaccharide in diabetic rats

Experimental and Clinical Endocrinology and Diabetes

Volumn 117, Issue 9, 2009, Pages 463-469

  Zhong, L Y ^a   Yang, Z H ^b   Li, X R ^a   Wang, H ^a   Li, L ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Cytokines; Diabetes; HPA axis; Lipopolysaccharide; Melatonin

Indexed keywords

CORTICOSTERONE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; GLUCOSE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MELATONIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; GLUCOSE HOMEOSTASIS; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MALE; NEUROENDOCRINE DISEASE; NEUROENDOCRINE IMMUNE DAMAGE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

ADRENOCORTICOTROPIC HORMONE; ANALYSIS OF VARIANCE; ANIMALS; ANTIOXIDANTS; CORTICOSTERONE; CORTICOTROPIN-RELEASING HORMONE; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INFLAMMATION; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MALE; MELATONIN; NEUROIMMUNOMODULATION; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PITUITARY-ADRENAL SYSTEM; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 71049134382     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0029-1202790     Document Type: Article

References (28)

1. Araya AV, Pavez V, Perez C, et al. Ex vivo lipopolysaccharide (LPS)-induced TNF-alpha, IL-1beta, IL-6 and PGE2secretion in whole blood from Type 1 diabetes mellitus patients with or without aggressive periodontitis. Eur Cytokine Netw 2003 14 128-133
2. Borjigin J, Li XD, Snyder SH, et al. The pineal gland and melatonin:molecular and pharmacologic regulation. Ann Rev Pharmacol Toxicol 1999 39 53-65
3. Bellipanni G, Bianchi P, Pierpaoli W, et al. Effects of melatonin in per-menopausal and menopausal women: a randomized and placebo controlled study. Exp Gerontol 2001 36 297-310
4. Chan O, Inouye K, Vranic M, et al. Hyperactivation of the hypothalamo-pituitary-adrenocortical axis in streptozotocin-diabetes is associated with reduced stress responsiveness and decreased pituitary and adrenal sensitivity. Endocrinology 2002 143 1761-1768
5. Chan O, Inouye K, Riddell MC, et al. Diabetes and the hypothalamo-pituitary-adrenal (HPA) axis. Minerva Endocrinolpgica 2003 28 87-102
6. Cam M, Yavuz O, Guven A, et al. Protective effects of chronic melatonin treatment against renal injury in streptozotocin-induced diabetic rats. J Pineal Res 2003 35 212-220
7. Defrance R, Quera-Salva MA. Therapeutic applications of melatonin and related compounds. Hormone Research 1998 49 142-146
8. Derlacz RA, Sliwinska M, Piekutowska A, et al. Melatonin is more effective than taurine and 5-hydroxytryptophan against hyperglycemia-induced kidney-cortex tubules injury. J Pineal Res 2007 42 203-209
9. Turek FW. Circadian rhythms. Horm Res 1998 49 109-113
10. Geoffriau M, Brun J, Chazot G, et al. The physiology and pharmacology of melatonin in humans. Hormone Research 1998 49 136-141
11. Gohil BC, Rosenblum LA, Coplan JD, et al. Hypothalamic-pituitary-adrenal axis function and the metabolic syndrome X of obesity. CNS Spectrums 2001 6 581-589
12. Gorgun FM, Kokoglu E, Gumustas MK, et al. Effects of melatonin on plasma S-nitrosoglutathione and glutathione in streptozotocin-treated rats. Journal of Toxicology and Environmental Health. Part A 2004 67 979-986
13. Konakchieva R, Mitev Y, Almeiga OF, et al. Chronic melatonin treatment and the hypothalamus-pituitary axis in the rat: attenuation of the secretary response to stress and effects on hypothalamic neuropeptide content and release. Biology Cell 1997 89 587-596
14. Konakchieva R, Mitev Y, Almeiga OF, et al. Chronic melatonin treatment counteracts glucocorticoid-induced dysregulation of the hypothalamic-pituitary- adrenal axis in the rat. Neuroendocrinology 1998 67 171-180
15. Kostoglou-Athanassiou I, Treachert DF, Wheeler MJ, et al. Melatonin administration and pituitary hormone secretion. Clinical Endocrinology 1998 48 31-37 (Pubitemid 28122430)
16. Kurcer Z, Parlakpinar H, Vardi N, et al. Protective effects of chronic melatonin treatment against renal ischemia/reperfusion injury in streptozotocin-induced diabetic rats. Exp Clin Endocrinol Diabetes 2007 115 365-371
17. Kanter M, Uysal H, Karaca T, et al. Depression of glucose levels and partial restoration of pancreatic beta-cell damage by melatonin in streptozotocin-induced diabetic rats. Arch Toxicol 2006 80 362-369
18. Luboshitzky R. Endocrine activity during sleep. J Pediatr Endocrinol Metab 2000 13 13-20
19. Oktem F, Ozguner F, Yilmaz HR, et al. Melatonin reduces urinary excretion of N-acetyl-beta-D-glucosaminidase, albumin and renal oxidative markers in diabetic rats. Clin and Exp Pharmacol & Physiol 2006 33 95-101
20. Pickup JC, Chusney GD, Thomas SM, et al. Plasma interleukin-6, tumour necrosis factor alpha and blood cytokine production in type 2 diabetes. Life Sciences 2000 67 291-300
21. Ran RQ, Lu AG, Zhang L, et al. Hsp70 promotes TNF-mediated apoptosis by binding IKK and impairing NF-kB survival signaling. Gene Develop 2004 18 1466-1481
22. Sacco S, Aquilini L, Ghezzi P, et al. Mechanism of the inhibitory effect of melatonin on tumor necrosis factor production in vivo and in vitro. Eur J Pharmacol 1998 343 249-255
23. Soop M, Duxbury H, Agwunobi AO, et al. Euglycemic hyperinsulinemia augments the cytokine and endocrine responses to endotoxin in humans. Am J Physiol Endocrinol Metab 2002 282 E1276-1285
24. Sudnikovich EJ, Maksimchik YZ, Zabrodskaya SV, et al. Melatonin attenuates metabolic disorders due to streptozotocin-induced diabetes in rats. Eur J Pharmacol 2007 569 180-187
25. Wehr TA. Effect of seasonal changes in daylength on human neuroendocrine function. Horm Res 1998 49 118-124
26. Winiarska K, Fraczyk T, Malinska D, et al. Melatonin attenuates diabetes-induced oxidative stress in rabbits. J Pin Res 2006 40 168-176
27. Yavuz O, Cam M, Bukan N, et al. Protective effect of melatonin on beta-cell damage in streptozotocin-induced diabetes in rats. Acta Histochemistry 2003 105 261-266 (Pubitemid 37046259)
28. Zhong LY, Jin H, Gao F, et al. Exogenous melatonin inhibited the function of pituitary-adrenal in alloxan-induced diabetic rats. Chin J of Endocrinol Metab 2003 19 141-143