Chronic melatonin treatment and the hypathalamo-pituitary-adrenal axis in the rat: Attenuation of the secretory response to stress and effects on hypothalamic neuropeptide content and release

Biology of the Cell

Volumn 89, Issue 9, 1997, Pages 587-596

  Konakchieva, Rossitza ^a,b,e   Mitev, Yuri ^c   Almeida, Osborne F X ^b   Patchev, Vladimir K ^b,d  

^a BULGARIAN ACADEMY OF SCIENCES   (Bulgaria)

^b MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^c INSTITUTE OF PHYSIOLOGY   (Bulgaria)

^d BAYER PHARMA AG   (Germany)

^e CNRS   (France)

Author keywords

ACTH; Corticosterone; CRH; In vitro release; Melatonin; Stress; Vasopressin

Indexed keywords

ARGIPRESSIN; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; MELATONIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CORTICOTROPIN RELEASE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0031396010     PISSN: 02484900     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0248-4900(98)80163-9     Document Type: Article

References (71)

1. Acuna D, Garcia Del Rio C, Garcia Torres L, Luna J and Osorio C (1984) Role of pineal gland in kidney-adrenal homeostasis. Horm Metab Res 16, 589-592
2. Akana SF, Cascio CS, Du JZ, Levin N and Dallman MF (1986) Reset of feedback in the adrenocortical system: an apparent shift in sensitivity of adrenocorticotropin to inhibition by corticosterone between morning and evening. Endocrinology 119, 2325-2332
3. Angeli A, Gatti G and Masera R (1994) Chronobiology of the hypothalamtc-pituitary-adrenal and renin-angiotensin-aldosterone systems. In: Biological Rhythms in Clinical and Laboratory Medicine (Touitou Y and Haus E, eds) Springer, Berlin, 292-313
4. Aoyama H, Mori N and Mori W (1987) Anti-glucocorticoid effects of melatonin in adult rats. Acta Pathol Jpn 37, 1143-1148
5. Arendt J (1988) Melatonin. Clin Endocrinol 29, 205-229
6. Beck-Friis J, Ljunggren JG, Thoren M, Von Rosen D, Kjellman BF and Wetterberg L (1985a) Melatonin, cortisol and ACTH in patients with major depressive disorder and healthy humans with special reference to the outcome of the dexamethasone suppression test. Psychoneuroendocrinology 10, 173-186
7. Beck-Friis J, Kjellman BF, Aperia B, Unden F, Von Rosen D, Ljunggren JG and Wetterberg L (1985b) Serum melatonin in relation to clinical variables in patients with major depressive disorder and a hypothesis of a low melatonin syndrome. Acta Psychiatr Scand 71, 319-330
8. Bojanowska E and Forsling ML (1997) The effects of melatonin on vasopressin secretion in vivo: interactions with acetylcholine and prostaglandins. Brain Res Bull 42, 457-461
9. Braughler JM (1985) Lipid peroxidation-induced inhibition of gamma-aminobutyric acid uptake in rat brain synaptosomes:protection by glucocorticoids. J Neurochem 44, 1282-1288
10. Brown R, Kocsis JH, Caroff S, Amsterdam J, Winokur A, Stokes PE and Frazer A (1985) Differences in nocturnal melatonin secretion between melancholic depressed patients and control subjects. Am J Psychiatry 142, 811-816
11. Cassone VM (1990) Effects of melatonin on vertebrate systems. Trends Neurosci 13, 457-464
12. Cassone VM, Chesworth MJ and Armstrong SM (1986) Dose-dependent entrainment of rat circadian rhythms by daily injection of melatonin. J Biol Rhythms 1, 219-229
13. Champney TH, Prado J, Youngblood T, Appel K and McMurray D (1997). Immune responsiveness of splenocytes after chronic daily melatonin administration in male Syrian hamsters. Immunol Lett 58, 95-100
14. Chowdrey HS, Larsen PJ, Harbuz MS, Jessop DS, Aguilera G, Eckland DJA and Lightman SL (1995) Evidence for arginine vasopressin as the primary activator of the HPA axis during adjuvant-induced arthritis. Br J Pharmacol 116, 2417-2424
15. Dallman M, Akana S, Cascio C, Darlington D, Jacobson L and Levin N (1987) Regulation of ACTH secretion: variation on a theme of B. Rec Progr Horm Res 43, 113-173
16. Davis LG, Arentzen R, Reid JM, Manning RW, Wolf son B, Lawrence KL and Baldino JF (1986) Glucocorticoid sensitivity of vasopressin mRNA levels in the paraventricular nucleus of the rat. Proc Natl Acad Sci USA 83, 1145-1149
17. De Goeij D, Dijkstra H and Tilders F (1992) Chronic psychological stress enhances vasopressin but not corticotropin-releasing factor, in the external zone of the median eminence of male rats: relationship to subordinate status. Endocrinology 131, 847-853
18. Ferrari E, Magri F, Dori D, Migliorati G, Nescis T, Molla G, Fioravanti M and Solerte SB (1995) Neuroendocrine correlates of the aging brain in humans. Neuroendocrinology 61, 464-470
19. Ferreira SA, Rollag MD and Glass JD (1996) Pharmacokinetics of extracellular melatonin in Siberian hamster forebrain. Brain Res 733, 318-320
20. Forsling ML, Stoughton RP, Zhou Y, Kelestimur H and Demaine C (1993) The role of the pineal in the control of the daily patterns of neurohypophysial hormone secretion. J Pineal Res 14, 45-51
21. Fraser S, Cowen P, Franclin M, Franey C and Arendt J (1983) Direct RIA for melatonin in plasma. Clin Chem 29, 396-397
22. Gauer F, Masson-Pévet M, Stehle J and Pévet P (1994) Daily variations in melatonin receptor density in rat pars tuberalis and suprachiasmatic nuclei are distinctly regulated. Brain Res 641, 92-98
23. Golombek DA, Escolar E, Burin L, Brito Sanchez MG and Cardinali DP (1992) Chronopharmacology of melatonin: inhibition by benzodiazepine antagonism. Chronobiol Int 9, 124-131
24. Harbuz MS, Rees RG, Eckland D, Jessop DS, Brewerton D and Lightman SL (1992) Paradoxical responses of hypothalamic CRF mRNA and CRF-41 peptide and adenohypophysial POMC mRNA during chronic inflammatory stress. Endocrinology 130, 1394-1400
25. Hastings M (1991) Neuroendocrine rhythms. Pharmacol Ther 50, 35-71
26. Herman JP, Prewitt CM and Cullinan WE (1996) Neuronal circuit regulation of the hypothalamo-pituitary-adrenocortical stress axis. Clin Rev Neurobiol 10, 371-394
27. Hillhouse EW and Milton NGN (1989) Effect of noradrenaline and γ-aminobutyric acid on the secretion of corticotropin-releasing factor-41 and arginine-vasopressin from the rat hypothalamus in vitro. J Endocrinol 122, 719-723
28. Holsboer F (1995) Neuroendocrinology of mood disorders. In: Psychopharmacology:The Fourth Generation of Progress (Bloom FE and Kupfer DJ, eds) Raven Press, New York, 957-969
29. Jones MT, Hillhouse EW and Burden J (1976) Effect of various putative neurotransmitters on the secretion of corticotropin-releasing hormone from the rat hypothalamus in vitro. A model for the neurotransmitters involved. J Endocrinol 69, 1-10
30. Kalsbeek A, Buijs RM, van Heerikhuize JJ, Arts M and van der Woude TP (1992) Vasopressin-containing neurons of the suprachiasmatic nuclei inhibit corticosterone release. Brain Res 580, 62-67
31. Kalsbeek A, van der Vliet J and Buijs RM (1996a) Decrease of endogenous vasopressin release necessary for expression of the circadian rise in plasma corticosterone: a microdialysis study. J Neuroendocrinol 8, 299-307
32. Kalsbeek A, van-Heerikhuize JJ, Wortel J and Buijs RM (1996b) A diurnal rhythm of stimulatory input to the hypothalamo-pituitary-adrenal system as revealed by timed intrahypothalamic administration of the vasopressin V1 antagonist. J Neurosci 16, 5555-5565
33. Kellner M, Yassouridis A, Manz B, Steiger A, Holsboer F and Wiedemann K (1997) Corticotropin-releasing hormone inhibits melatonin secretion in healthy volunteers. A potential link to low-melatonin syndrome in depression? Neuroendocrinology 65, 284-290
34. Konakchieva R, Mitev Y, Almeida OFX and Patchev V (1998) Chronic melatonin treatment counteracts glucocorticoid-induced dysregulation of the hypothalamic-pituitary-adrenal axis in the rat. Neuroendocrinology, in press
35. Laitinen JT, Catren E, Vakkuri O and Saavedra JM (1989) Diurnal rhythm of melatonin binding in the rat suprachiasmatic nucleus. Endocrinology 124, 1585-1587
36. Lincoln G and Clarke IJ (1994) Photoperiodically-induced cycles in secretion of prolactin in hypothalamo-pituitary disconnected rams. Evidence for translation of the melatonin signal in the pituitary gland. J Neuroendocrinol 6, 251-260
37. Lynch HJ and Deng MH (1986) Pineal response to stress. J Neural Transm (suppl) 21, 461-473
38. Marinova C, Persengiev S, Konakchieva R, Ilieva A and Patchev V (1991) Melatonin effects on glucocorticoid receptors in rat brain and pituitary: significance in adrenocortical regulation. Int J Biochem 23, 479-481
39. Maywood E, Bittman E, Ebling F, Barett P, Morgan P and Hastings M (1995) Regional distribution of iodomelatonin binding sites within the suprachiasmatic nucleus of the Syrian hamster and the Siberian hamster. J Neuroendocrinol 7, 215-223
40. McArthur A, Gillette M and Prosser R (1991) Melatonin directly resets the rat suprachiasmatic cidrcadian clock in vitro. Brain Res 565, 158-161
41. Moore R (1983) Organization and function of a central nervous system circadian oscillator: the suprachiasmatic nucleus. Fed Proc 42, 2783-2789
42. Moore R and Eichler V (1972) Loss of circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat. Brain Res 42, 201-206
43. Moore R and Klein D (1974) Visual pathways and the central control of a circadian rhythm in pineal serotonin N-acetyl-transferase activity. Brain Res 71, 17-33
44. Neu JM and Niles LP (1997) A marked diurnal rhythm of ML1a receptor mRNA expression in the suprachiasmatic nucleus. Mol Brain Res 49, 303-306
45. Noto T, Hashimoto H, Doi Y, Nawajima T and Kato N (1983) Biorhythms of arginine-vasopressin in the paraventricular supraoptic and suprachiasmatic nuclei of rats. Peptides 4, 875-878
46. Patchev VK, Kalogeras KT, Zelazowski P, Wilder RL and Chrousos GP (1992) Increased plasma concentrations, hypothalamic content, and in vitro release of arginine vasopressin in inflammatory disease-prone, hypothalamic corticotropin-releasing hormone-deficient Lewis rats. Endocrinology 131, 1453-1457
47. Patchev VK, Karalis K and Chrousos G (1994) Effects of excitatory amino acid transmitters on hypothalamîc corticotropin-releasing hormone (CRH) and arginine-vasopressin (AVP) release in vitro: implications in pituitary-adrenal regulation. Brain Res 633, 312-316
48. Persengiev SP, Kanchev LN and Stankov BM (1989) Effect of melatonin on steroid production by rat adrenals under in vitro superfusion conditions. Life Sci 44, 1955-1962
49. Persengiev S, Kanchev L and Vezenkova G (1991) Circadian patterns of melatonin, corticosterone, and progesterone in male rats subjected to chronic stress: effect of constant illumination. J Pineal Res 11, 57-62
50. Pévet P (1987) Environmental control of the annual reproductive cycle in mammals. In: Comparative Physiology of Environmental Adaptations, vol 3 (Pévet P, ed) Karger, Basel, 82-100
51. Pierpaoli W and Maestroni G (1987) Melatonin, a principal neuroimmunoregulatory and anti-stress hormone: its anti-aging effects. Immunol Lett 16, 355-362
52. Raynaud F, Mauviard F, Geoffriau M, Claustrat B and Pévet P (1993) Plasma 6-hydroxymelaton in, 6-sulfatoxymelatonin and melatonin kinetics after melatonin administration to rats, Biol Signals 2, 359-366
53. Recio J, Pévet P, Miguez J and Masson-Pévet M (1996) Melatonin receptors in the suprachiasmatic nuclei and pars tuberalis of testosterone induced photoresponsive rats. Neurosci Lett 214, 53-56
54. Reppert SM, Perlow MJ, Ungerleider LG, Mishkin M, Tamarkin L, Orloff DG, Hoffman HJ and Klein DC (1981) Effects of damage to the suprachiasmatic area of the anterior hypothalamus on the daily melatonin and cortisol rhythms in the rhesus monkey. J Neurosci 1, 1414-1425
55. Reppert SM, Weaver DR and Ebisawa T (1994) Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron 13, 1177-1185
56. Sapolsky RM and Plotsky PM (1990) Hypercorticalism and its possible neural bases. Biol Psychiatry 27, 937-952
57. Sapolsky RM, Krey LC and McEwen BS (1986) The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis. Endocrinol Rev 7, 284-301
58. Seggie J, Campbell L, Brown G and Grota L (1985) Melatonin and N-acetylserotonin stress responses: effect of stimulation and housing conditions. J Pineal Res 2, 39-49
59. Shibata S, Cassone V and Moore R (1989) Effect of melatonin on neuronal activity in the rat suprachiasmatic nucleus in vitro. Neurosci Lett 97, 140-144
60. Siaud P, Mekaouche M, Maurel D, Givalois L and Ixart G (1994) Superior cervical ganglionectomy suppresses corticotropic rhythms in male rats in the short term (5 days) and long term (10 days). Brain Res 652, 273-278
61. Stankov B, Biella B, Panara C, Lucini V, Capsoni S, Fautek J, Cozzi B and Fraschini F (1991) Melatonin signal transduction and mechanism of action in the central nervous system: using the rabbit cortex as a model. Endocrinology 130, 2152-2159
62. Strassman RJ, Appenzeller D, Lewy AJ, Qualls CR and Peake GT (1989) Increase in plasma melatonin, β-endorphin and cortisol after a 28.5-mile mountain race: relationship to performance and lack of effect of naltrexone. J Clin Endocrinol Metab 69, 540-545
63. Sumova A, Ebling F, Maywood E, Herbert J and Hastings M (1994) Non-photic circadian entrainment in the Syrian hamster is not associated with phosphorylation of the transcriptional regulator CREB within the suprachiasmatic nucleus, but is associated with adrenocortical activation. Neuroendocrinology 59, 579-589
64. Swain MG, Patchev V, Vergalla J, Chrousos G and Jones EA (1992) Suppression of hypothalamic-pituitary-adrenal axis responsiveness to stress in a rat model of acute cholestasis. J Clin Invest 91, 1903-1908
65. Tamarkin L, Baird CJ and Almeida OFX (1985) Melatonin: a coordinating signal for mammalian reproduction? Science 227, 714-720
66. Turek FW (1985) Circadian neural rhythms in mammals. Annu Rev Physiol 47, 49-54
67. Waldhauser F, Steiger H and Vorkapic P (1987) Melatonin secretion in man and the influence of exogenous melatonin on some physiological and behavioural variables. Adv Pineal Res 2, 207-223
68. Weidenfield Y, Schmidt U and Nir I (1993) The effect of melatonin on the HPA axis in intact and pinealectomized rats under basal and stressed conditions. J Pineal Res 14, 60-66
69. Wetterberg L (1983) The relationship between the pineal gland and the pituitary-adrenal axis in health, endocrine and psychiatric conditions. Psychoneuroendocrinology 8, 75-80
70. Windle RJ, Luckman SM, Stoughton RP and For sling ML (1996) The effect of pinealectomy on osmotically stimulated vasopressin and oxytocin release and Fos protein production within the hypothalamus of the rat. J Neuroendocrinol 8, 747-753
71. Yasin S, Costa A, Besser GM, Hucks D, Grossman A and Forsling ML (1993) Melatonin and its analogs inhibit tha basal and stimulated release of hypothalamic vasopressin and oxytocin in vitro. Endocrinology 132, 1329-1336