-
1
-
-
22844436226
-
Recent advances in tumor-targeting anticancer drug conjugates
-
DOI 10.1016/j.bmc.2005.04.084, PII S0968089605003767
-
Jaracz S, Chen J, Kuznetsova LV, et al. Recent advances in tumor-targeting anticancer drug conjugates [J]. Bioorg Med Chem, 2005, 13: 5043-5054. (Pubitemid 41039965)
-
(2005)
Bioorganic and Medicinal Chemistry
, vol.13
, Issue.17
, pp. 5043-5054
-
-
Jaracz, S.1
Chen, J.2
Kuznetsova, L.V.3
Ojima, I.4
-
2
-
-
64549126535
-
Folate receptor-mediated antitumor drugs
-
J
-
Zhao J, Cao SL, Zheng XL, et al. Folate receptor-mediated antitumor drugs [J]. Acta Pharm Sin, 2009, 44: 109-114.
-
(2009)
Acta Pharm Sin
, vol.44
, pp. 109-114
-
-
Zhao, J.1
Cao, S.L.2
Zheng, X.L.3
-
3
-
-
0014931204
-
Selective destruction of target cells by diphtheria toxin conjugated to antibody directed against antigens on the cells
-
J
-
Moolten FL, Cooperband SR. Selective destruction of target cells by diphtheria toxin conjugated to antibody directed against antigens on the cells [J]. Science, 1970, 169: 68-70.
-
(1970)
Science
, vol.169
, pp. 68-70
-
-
Moolten, F.L.1
Cooperband, S.R.2
-
4
-
-
33644809991
-
Antitumor effect of the novel immunoconjugate composed of pingyangmycin and anti-type IV collagenase monoclonal antibody
-
J
-
Dai Y, Liu XJ, Zhen YS. Antitumor effect of the novel immunoconjugate composed of pingyangmycin and anti-type IV collagenase monoclonal antibody [J]. Acta Pharm Sin, 2006, 41: 41-46.
-
(2006)
Acta Pharm Sin
, vol.41
, pp. 41-46
-
-
Dai, Y.1
Liu, X.J.2
Zhen, Y.S.3
-
5
-
-
65349154663
-
Novel immunoconjugates comprised of streptonigrin and 17-amino-geldanamycin attached via a dipeptide-p-aminobenzyl-amine linker system
-
J
-
Burke PJ, Toki BE, Meyer DW, et al. Novel immunoconjugates comprised of streptonigrin and 17-amino-geldanamycin attached via a dipeptide-p-aminobenzyl- amine linker system [J]. Bioorg Med Chem Lett, 2009, 19: 2650-2653.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 2650-2653
-
-
Burke, P.J.1
Toki, B.E.2
Meyer, D.W.3
-
6
-
-
0034900174
-
Approval summary: Gemtuzumab ozogamicin in relapsed acute myeloid leukemia
-
Bross PF, Beitz J, Chen G, et al. Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia [J]. Clin Cancer Res, 2001, 7: 1490-1496. (Pubitemid 32708610)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.6
, pp. 1490-1496
-
-
Bross, P.F.1
Beitz, J.2
Chen, G.3
Xiao Hong, C.4
Duffy, E.5
Kieffer, L.6
Roy, S.7
Sridhara, R.8
Rahman, A.9
Williams, G.10
Pazdur, R.11
-
7
-
-
33744537358
-
Lysosomal trafficking and cysteine protease metabolism confer target-specific cytotoxicity by peptide-linked anti-CD30-auristatin conjugates
-
J
-
Sutherland MS, Sanderson RJ, Gordon KA, et al. Lysosomal trafficking and cysteine protease metabolism confer target-specific cytotoxicity by peptide-linked anti-CD30-auristatin conjugates [J]. J Biol Chem, 2006, 281: 10540-10547.
-
(2006)
J Biol Chem
, vol.281
, pp. 10540-10547
-
-
Sutherland, M.S.1
Sanderson, R.J.2
Gordon, K.A.3
-
8
-
-
27944502827
-
Dipeptide-based highly potent doxorubicin antibody conjugates
-
J
-
Jeffrey SC, Nguyen MT, Andreyka JB, et al. Dipeptide-based highly potent doxorubicin antibody conjugates [J]. Bioorg Med Chem Lett, 2006, 16: 358-362.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 358-362
-
-
Jeffrey, S.C.1
Nguyen, M.T.2
Andreyka, J.B.3
-
9
-
-
33746095034
-
Potent cytotoxicity of an auristatin-containing antibody-drug conjugate targeting melanoma cells expressing melanotransferrin/p97
-
DOI 10.1158/1535-7163.MCT-06-0026
-
Smith LM, Nesterova A, Alley SC, et al. Potent cytotoxicity of an auristatin-containing antibody-drug conjugate targeting melanoma cells expressing melanotransferrin/p97 [J]. Mol Cancer Ther, 2006, 5: 1474-1482. (Pubitemid 44070484)
-
(2006)
Molecular Cancer Therapeutics
, vol.5
, Issue.6
, pp. 1474-1482
-
-
Smith, L.M.1
Nesterova, A.2
Alley, S.C.3
Torgov, M.Y.4
Carter, P.J.5
-
10
-
-
34547131841
-
Antibody-drug conjugates targeted to CD79 for the treatment of non-Hodgkin lymphoma
-
J
-
Poison AG, Yu SF, Elkins K, et al. Antibody-drug conjugates targeted to CD79 for the treatment of non-Hodgkin lymphoma [J]. Blood, 2007, 110: 616-623.
-
(2007)
Blood
, vol.110
, pp. 616-623
-
-
Poison, A.G.1
Yu, S.F.2
Elkins, K.3
-
12
-
-
33644505446
-
Lymphocyte activation antigen CD70 expressed by renal cell carcinoma is a potential therapeutic target for anti-CD70 antibody-drug conjugates
-
J
-
Law CL, Gordon KA, Toki BE, et al. Lymphocyte activation antigen CD70 expressed by renal cell carcinoma is a potential therapeutic target for anti-CD70 antibody-drug conjugates [J]. Cancer Res, 2006, 66: 2328-2337.
-
(2006)
Cancer Res
, vol.66
, pp. 2328-2337
-
-
Law, C.L.1
Gordon, K.A.2
Toki, B.E.3
-
13
-
-
34247560840
-
CD20-specific antibody-targeted chemotherapy of non-Hodgkin's B-cell lymphoma using calicheamicin-conjugated rituximab
-
J
-
DiJoseph JF, Dougher MM, Armellino DC, et al. CD20-specific antibody-targeted chemotherapy of non-Hodgkin's B-cell lymphoma using calicheamicin-conjugated rituximab [J]. Cancer Immunol Immunother, 2007, 56: 1107-1117.
-
(2007)
Cancer Immunol Immunother
, vol.56
, pp. 1107-1117
-
-
DiJoseph, J.F.1
Dougher, M.M.2
Armellino, D.C.3
-
14
-
-
9744243565
-
Efficient elimination of B-lineage lymphomas by anti-CD20-auristatin conjugates
-
J
-
Law CL, Cerveny CG, Gordon KA, et al. Efficient elimination of B-lineage lymphomas by anti-CD20-auristatin conjugates [J]. Clin Cancer Res, 2004, 10: 7842-7851.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7842-7851
-
-
Law, C.L.1
Cerveny, C.G.2
Gordon, K.A.3
-
15
-
-
1242352458
-
Internalization and cell cycle-dependent killing of leukemic cells by Gemtuzumab Ozogamicin: Rationale for efficacy in CD33-negative malignancies with endocytic capacity
-
DOI 10.1038/sj.leu.2403205
-
Jedema I, Barge RM, van der Velden VH, et al. Internalization and cell cycle-dependent killing of leukemic cells by gemtuzumab ozogamicin: rationale for efficacy in CD33-negative malignancies with endocytic capacity [J]. Leukemia, 2004, 18: 316-325. (Pubitemid 38240048)
-
(2004)
Leukemia
, vol.18
, Issue.2
, pp. 316-325
-
-
Jedema, I.1
Barge, R.M.Y.2
Van Der Velden, V.H.J.3
Nijmeijer, B.A.4
Van Dongen, J.J.M.5
Willemze, R.6
Falkenburg, J.H.F.7
-
16
-
-
22344432668
-
Anti-CD74 antibody-doxorubicin conjugate, IMMU-110, in a human multiple myeloma xenograft and in monkeys
-
DOI 10.1158/1078-0432.CCR-05-0204
-
Sapra P, Stein R, Pickett J, et al. Anti-CD74 antibody-doxorubicin conjugate, IMMU-110, in a humanmultiplemyeloma xenograft and in monkeys [J]. Clin Cancer Res, 2005, 11: 5257-5264. (Pubitemid 41003714)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.14
, pp. 5257-5264
-
-
Sapra, P.1
Stein, R.2
Pickett, J.3
Qu, Z.4
Govindan, S.V.5
Cardillo, T.M.6
Hansen, H.J.7
Horak, I.D.8
Griffiths, G.L.9
Goldenberg, D.M.10
-
17
-
-
0037137606
-
Tumor-specific novel taxoid-monoclonal antibody conjugates
-
DOI 10.1021/jm025540g
-
Ojima I, Geng XD, Wu XY, et al. Tumor-specific novel taxoid-monoclonal antibody conjugates [J]. J Med Chem, 2002, 45: 5620-5623. (Pubitemid 35453753)
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, Issue.26
, pp. 5620-5623
-
-
Ojima, I.1
Geng, X.2
Wu, X.3
Qu, C.4
Borella, C.P.5
Xie, H.6
Wilhelm, S.D.7
Leece, B.A.8
Bartle, L.M.9
Goldmacher, V.S.10
Chari, R.V.J.11
-
18
-
-
38949192547
-
Targeted cancer therapy: Conferring specificity to cytotoxic drugs
-
J
-
Chari RV. Targeted cancer therapy: conferring specificity to cytotoxic drugs [J]. Acc Chem Res, 2008, 41: 98-107.
-
(2008)
Acc Chem Res
, vol.41
, pp. 98-107
-
-
Chari, R.V.1
-
19
-
-
38949184547
-
Selection of reaction additives used in the preparation of monomeric antibody-calicheamicin conjugates
-
DOI 10.1021/bc700321z
-
Hollander I, Kunz A, Hammann PR. Selection of reaction additives used in the preparation of monomeric antibody-calicheamicin conjugates [J]. Bioconjug Chem, 2008, 19: 358-361. (Pubitemid 351213870)
-
(2008)
Bioconjugate Chemistry
, vol.19
, Issue.1
, pp. 358-361
-
-
Hollander, I.1
Kunz, A.2
Hamann, P.R.3
-
20
-
-
20144375952
-
An anti-MUC1 antibody-calicheamicin conjugate for treatment of solid tumors. Choice of linker and overcoming drug resistance
-
J
-
Hamann PR, Hinman LM, Beyer CF, et al. An anti-MUC1 antibody- calicheamicin conjugate for treatment of solid tumors. Choice of linker and overcoming drug resistance [J]. Bioconjug Chem, 2005, 16: 346-353.
-
(2005)
Bioconjug Chem
, vol.16
, pp. 346-353
-
-
Hamann, P.R.1
Hinman, L.M.2
Beyer, C.F.3
-
21
-
-
10744229449
-
Antibody-targeted chemotherapy with CMC-544: A CD22-targeted immunoconjugate of calicheamicin for the treatment of B-lymphoid malignancies
-
J
-
DiJoseph JF, Armellino DC, Boghaert ER, et al. Antibody-targeted chemotherapy with CMC-544: a CD22-targeted immunoconjugate of calicheamicin for the treatment of B-lymphoid malignancies [J]. Blood, 2004, 103: 1807-1814.
-
(2004)
Blood
, vol.103
, pp. 1807-1814
-
-
DiJoseph, J.F.1
Armellino, D.C.2
Boghaert, E.R.3
-
22
-
-
3042770596
-
Antibody-targeted chemotherapy with the calicheamicin conjugate hu3S193-N-acetyl γ calicheamicin dimethyl hydrazide targets Lewis Y and eliminates Lewis Y positive human carcinoma cells and xenografts
-
J
-
Boghaert ER, Sridharan L, Armellino DC, et al. Antibody-targeted chemotherapy with the calicheamicin conjugate hu3S193-N-acetyl γ calicheamicin dimethyl hydrazide targets Lewis Y and eliminates Lewis Y positive human carcinoma cells and xenografts [J]. Clin Cancer Res, 2004, 10: 4538-4549.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4538-4549
-
-
Boghaert, E.R.1
Sridharan, L.2
Armellino, D.C.3
-
23
-
-
33645500289
-
Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing
-
J
-
Erickson HK, Park PU, Widdison WC, et al. Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing [J]. Cancer Res, 2006, 66: 4426-4433.
-
(2006)
Cancer Res
, vol.66
, pp. 4426-4433
-
-
Erickson, H.K.1
Park, P.U.2
Widdison, W.C.3
-
24
-
-
9444223279
-
+ multiple myeloma cells
-
DOI 10.1182/blood-2004-03-0963
-
Tassone P, Goldmacher VS, Neri P, et al. Cytotoxic activity of the maytansinoid immunoconjugate B-B4-DM1 against CD138+ multiple myeloma cells [J]. Blood, 2004, 104: 3688-3696. (Pubitemid 39564446)
-
(2004)
Blood
, vol.104
, Issue.12
, pp. 3688-3696
-
-
Tassone, P.1
Goldmacher, V.S.2
Neri, P.3
Gozzini, A.4
Shammas, M.A.5
Whiteman, K.R.6
Hylander-Gans, L.L.7
Carrasco, D.R.8
Hideshima, T.9
Shringarpure, R.10
Shi, J.11
Allam, C.K.12
Wijdenes, J.13
Venuta, S.14
Munshi, N.C.15
Anderson, K.C.16
-
25
-
-
40449111659
-
Targeting CD56 by the maytansinoid immunoconjugate IMGN901 (huN901-DM1): A potential therapeutic modality implication against natural killer/T cell malignancy
-
DOI 10.1111/j.1365-2141.2008.07000.x
-
Ishitsuka K, Jimi S, Goldmacher VS, et al. Targeting CD56 by the maytansinoid immunoconjugate IMGN901 (huN901-DM1): a potential therapeutic modality implication against natural killer/T cell malignancy [J]. Br J Haematol, 2008, 141: 120-131. (Pubitemid 351347531)
-
(2008)
British Journal of Haematology
, vol.141
, Issue.1
, pp. 129-131
-
-
Ishitsuka, K.1
Jimi, S.2
Goldmacher, V.S.3
Ab, O.4
Tamura, K.5
-
26
-
-
34250613133
-
Treatment parameters modulating regression of human melanoma xenografts by an antibody-drug conjugate (CR011-vcMMAE) targeting GPNMB
-
DOI 10.1007/s00280-007-0490-z
-
Pollack VA, Alvarez E, Tse KF, et al. Treatment parameters modulating regression of human melanoma xenografts by an antibody-drug conjugate (CR011-vcMMAE) targeting GPNMB [J]. Cancer Chemother Pharmacol, 2007, 60: 423-435. (Pubitemid 46944592)
-
(2007)
Cancer Chemotherapy and Pharmacology
, vol.60
, Issue.3
, pp. 423-435
-
-
Pollack, V.A.1
Alvarez, E.2
Tse, K.F.3
Torgov, M.Y.4
Xie, S.5
Shenoy, S.G.6
MacDougall, J.R.7
Arrol, S.8
Zhong, H.9
Gerwien, R.W.10
Hahne, W.F.11
Senter, P.D.12
Jeffers, M.E.13
Lichenstein, H.S.14
Larochelle, W.J.15
-
27
-
-
33646924550
-
Development and properties of β-glucuronide linkers for monoclonal antibody-drug conjugates
-
J
-
Jeffrey SC, Andreyka JB, Bernhardt SX, et al. Development and properties of β-glucuronide linkers for monoclonal antibody-drug conjugates [J]. Bioconjug Chem, 2006, 17: 831-840.
-
(2006)
Bioconjug Chem
, vol.17
, pp. 831-840
-
-
Jeffrey, S.C.1
Andreyka, J.B.2
Bernhardt, S.X.3
-
28
-
-
33745684533
-
Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment
-
DOI 10.1093/protein/gzl013
-
McDonagh CF, Turcott E, Westendorf L, et al. Engineered antibody-drug conjugates with defined sites and stoichiometrics of drug attachment [J]. Protein Eng Des Sel, 2006, 19: 299-307. (Pubitemid 43999640)
-
(2006)
Protein Engineering, Design and Selection
, vol.19
, Issue.7
, pp. 299-307
-
-
McDonagh, C.F.1
Turcott, E.2
Westendorf, L.3
Webster, J.B.4
Alley, S.C.5
Kim, K.6
Andreyka, J.7
Stone, I.8
Hamblett, K.J.9
Francisco, J.A.10
Carter, P.11
-
29
-
-
49449087300
-
Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index
-
J
-
Junutula JR, Raab H, Clark S, et al. Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index [J]. Nat Biotechnol, 2008, 26: 925-932.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 925-932
-
-
Junutula, J.R.1
Raab, H.2
Clark, S.3
-
30
-
-
34548438925
-
Antitumor activities of various immunoconjugates composed of lidamycin and anti-type IV collagenase monoclonal antibody
-
J
-
Feng Y, Zhen YS, Dai Y, et al. Antitumor activities of various immunoconjugates composed of lidamycin and anti-type IV collagenase monoclonal antibody [J]. Acta Pharm Sin, 2007, 42: 704-709.
-
(2007)
Acta Pharm Sin
, vol.42
, pp. 704-709
-
-
Feng, Y.1
Zhen, Y.S.2
Dai, Y.3
-
31
-
-
84871944055
-
HPMA copolymer-anticancer drug-OV-TL-TL16 antibody conjugates. 1. Influence of the method of synthesis on the biding affinity to OVCAR-3 ovarian carcinoma cells in vitro
-
J
-
Omelyanenko V, Kopeckova P, Gentry C, et al. HPMA copolymer-anticancer drug-OV-TL-TL16 antibody conjugates. 1. Influence of the method of synthesis on the biding affinity to OVCAR-3 ovarian carcinoma cells in vitro [J]. J Drug Target, 1993, 3: 3575-4373
-
(1993)
J Drug Target
, vol.3
, pp. 3575-4373
-
-
Omelyanenko, V.1
Kopeckova, P.2
Gentry, C.3
-
32
-
-
11444252496
-
Antibody-targeted polymer-doxorubicin conjugates with pH-controlled activation
-
DOI 10.1080/10611860400011869, Polymers in Drug Delivery
-
Ulbrich K, Etrych T, Chytil P, et al. Antibody-targeted polymer-doxorubicin conjugates with pH-controlled activation [J]. J Drug Target, 2004, 12: 477-489. (Pubitemid 40081303)
-
(2004)
Journal of Drug Targeting
, vol.12
, Issue.8
, pp. 477-489
-
-
Ulbrich, K.1
Etrych, T.2
Chytil, P.3
Jelinkova, M.4
Rihova, B.5
-
33
-
-
30344486996
-
Antibody conjugates and therapeutic strategies
-
J
-
McCarron PA, Olwill SA, Marouf WMY, et al. Antibody conjugates and therapeutic strategies [J]. Mol Interv, 2005, 5: 368-380.
-
(2005)
Mol Interv
, vol.5
, pp. 368-380
-
-
McCarron, P.A.1
Olwill, S.A.2
Marouf, W.M.Y.3
-
34
-
-
12244295755
-
In vivo drug-linker stability of an anti-CD30 dipeptide-linked auristatin immunoconjugate
-
J
-
Sanderson RJ, Hering MA, James SF, et al. In vivo drug-linker stability of an anti-CD30 dipeptide-linked auristatin immunoconjugate [J]. Clin Cancer Res, 2005, 11: 843-852.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 843-852
-
-
Sanderson, R.J.1
Hering, M.A.2
James, S.F.3
-
35
-
-
10744222473
-
Development of potent monoclonal antibody auristatin conjugates for cancer therapy
-
DOI 10.1038/nbt832
-
Doronina SO, Toki BE, Torgov MY, et al. Development of potent monoclonal antibody auristatin conjugates for cancer therapy [J]. Nat Biotechnol, 2003, 21: 778-784. (Pubitemid 36791396)
-
(2003)
Nature Biotechnology
, vol.21
, Issue.7
, pp. 778-784
-
-
Doronina, S.O.1
Toki, B.E.2
Torgov, M.Y.3
Mendelsohn, B.A.4
Cerveny, C.G.5
Chace, D.F.6
Deblanc, R.L.7
Gearing, R.P.8
Bovee, T.D.9
Siegall, C.B.10
Francisco, J.A.11
Wahl, A.F.12
Meyer, D.L.13
Senter, P.D.14
-
36
-
-
49449114385
-
Antibody-drug conjugates ace the tolerability test
-
J
-
Damle NK. Antibody-drug conjugates ace the tolerability test [J]. Nat Biotechnol, 2008, 26: 884-885.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 884-885
-
-
Damle, N.K.1
|