Influence of the formulation components on the properties of the system SLN-dextran hydrogel for the modified release of drugs

Journal of Microencapsulation

Volumn 26, Issue 4, 2009, Pages 355-364

  Paolicelli, Patrizia ^a   Cerreto, Felice ^a   Cesa, Stefania ^a   Feeney, Michelle ^a   Corrente, Federica ^a   Marianecci, Carlotta ^a   Casadei, Maria Antonietta ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Dextran methacrylate; Hydrogel; Ibuprofen; Modified release; Photochemical cross linking reaction; Solid lipid nanoparticles

Indexed keywords

DEXTRAN; GLYCEROL BEHENATE; GLYCEROL PALMITOSTEARATE; IBUPROFEN; POLYMER; SOLID LIPID NANOPARTICLE; SURFACTANT; WITEPSOL;

ARTICLE; DERIVATIZATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; FLOW KINETICS; HYDROGEL; LIPOPHILICITY; PHYSICAL CHEMISTRY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DEXTRANS; HYDROGEL; IBUPROFEN; LIPIDS; METHACRYLATES; NANOPARTICLES; RHEOLOGY; SURFACE-ACTIVE AGENTS;

EID: 70849133470     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.1080/02652040802372899     Document Type: Article

References (25)

1. Mü ller RH, Mäder K, Gohla S. Solid lipid nanoparticles (SLN) for controlled drug delivery a review of the state of art. Eur J Pharm Biopharm. 2000;50:161-177
2. Mehenert W, Mäder K. Solid lipid nanoparticles. Production, characterization and applications. Adv Drug Deliv Rev. 2001;47:165-196
3. Mü ller RH, Radtke M, Wissing SA. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. Adv Drug Deliv Rev. 2002;54:S131-55.
4. Almeida AJ, Runge S, Mü ller RH. Peptide-loaded solid lipid nanoparticles (SLN): Influence of production parameters. Int J Pharm. 1997;149:255-265 (Pubitemid 27193412)
5. Yang S, Zhu J, Lu Y, Liang B, Yang C. Body distribution of camptothecin solid lipid nanoparticles after oral administration. Pharm Res. 1999;16:751-757
6. Cavalli R, Zara GP, Caputo O, Bargoni A, Fundaro A, Gasco MR. Transmucosal transport of tobramycin incorporated in SLN after duodenal administration to rats. Part I. A pharmacokinetics study. Pharm Res. 2000;42:541-545
7. Fundaro A, Cavalli R, Bargoni A, Vighetto D, Zara GP, Gasco MR. Non-stealth and stealth solid lipid nanoparticles (SLN) carrying doxorubicin: Pharmacokinetics and tissue distribution after i.v. administration to rats. Pharm Res. 2000;42:337-343
8. Hu FQ, Hong Y, Yuan H. Preparation and characterization of solid lipid nanoparticles containing peptides. Int J Pharm. 2004;273:29-35. (Pubitemid 38317037)
9. Casadei MA, Cerreto F, Cesa S, Giannuzzo M, Feeney M, Marianecci C, et al. Solid lipid nanoparticles incorporated in dextran hydrogels: A new drug delivery system for oral formulations. Int J Pharm. 2006;325:140-146
10. Ahlin P, Kristl J, Smid-Koar J. Optimization of procedure parameters and physical stability of solid lipid nanoparticles in dispersion. Acta Pharm. 1998;48:257-267
11. Pitarresi G, Palumbo FS, Giammona G, Casadei MA, Micheletti Moracci F. Biodegradable hydrogels obtained by photocrosslinking of dextran and polyaspartamide derivatives. Biomaterials. 2003; 24:4301-4313
12. Van Dijk-Wolthuis WNE, Ketteness-Van Den Bosch JJ, Van Der Kerk- Van Hoof A, Hennink WE. Reaction of dextran with glycidyl methacrylate: An unexpected transesterification. Macromolecules. 1997; 30:3411-3413
13. Kim SH, Chu CC. Synthesis and characterization of dextran methacrylate hydrogels and structural studies by SEM. J Biomed Mater Res. 2000;49:517-527
14. Radtke M, Müller RH. Comparison of structural properties of solid lipid nanoparticles (SLNTM) versus other lipid particles. Proc Int Symp Contr Rel Bioact Mat. 2000;27:6118-6119
15. Brittain HG. Analytical profiles of drug substances and excipients. San Diego: Academic Press; 2001. pp 27-51.
16. Gouin S, Zhu XX. Fluorescence and NMR studies of the effect of a bile acid dimer on the micellization of bile salts. Langmuir. 1998; 14:4025-4029
17. Peppas NA, Bures P, Leobandung W, Ichikawa H. Hydrogels in pharmaceutical formulations. Eur J Pharm Biopharm. 2000;50:27-46.
18. Giannuzzo M, Corrente F, Feeney M, Paoletti L, Paolicelli P, Tita B., et al. 2008. pH-Sensitive hydrogels of dextran: Synthesis, characterization and in vivo studies. J Drug Targeting; in press.
19. Jenning V, Mäder K, Gohla SH. Solid lipid nanoparticles (SLNTM) based on binary mixtures of liquid and solid lipids: A 1H-NMR study. Int J Pharm. 2000;205:15-21. (Pubitemid 30734720)
20. Zimmermann E, Souto EB, Mü ller RH. Physicochemical investigations on the structure of drug-free and drug-loaded solid lipid nanoparticles (SLNTM) by means of DSC and 1H-NMR. Pharmazie. 2005;60:508-513
21. Hamdani J, Moës AJ, Amighi K. Physical and thermal characterization of Precirol- and Compritol- as lipophilic glycerides used for the preparation of controlled-release matrix pellets. Int J Pharm. 2003; 260:47-57.
22. Barry BW. Rheology of dermatological vehicles. In: Barry BW, editor. Dermatological formulations-Percutaneous absorption. Vol.18, New York: Marcel Dekker; 1983. pp 351-396
23. Lippacher A, Mü ller RH, Mäder K. Liquid and semisolid SLNTM dispersions for topical application: Rheological characterization. Eur J Pharm Biopharm. 2004;58:561-567
24. Souto EB, Wissing SA, Barbosa CM, Mü ller RH. Comparative study between the viscoelastic behaviours of different nanoparticle formulations. J Cosmet Sci. 2004;55:463-471
25. Giannuzzo M, Feeney M, Paolicelli P, Casadei MA. Synthesis and characterization of pH-sensitive hydrogels of dextran. J Drug Deliv Sci Tech. 2006;16:49-54.