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Volumn 30, Issue 11, 2009, Pages 1923-1926

Sulindac effects on inflammation and tumorigenesis in the intestine of mice with Apc and Mlh1 mutations

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; PROTEIN MLH1; SULINDAC;

EID: 70849089275     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgp200     Document Type: Article
Times cited : (10)

References (44)
  • 1
    • 0025834849 scopus 로고
    • Sulindac causes regression of rectal polyps in familial adenomatous polyposis
    • Labayle,D. et al. (1991) Sulindac causes regression of rectal polyps in familial adenomatous polyposis. Gastroenterology, 101 635-639.
    • (1991) Gastroenterology , vol.101 , pp. 635-639
    • Labayle, D.1
  • 2
    • 0027141503 scopus 로고
    • Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis
    • Nugent,K.P. et al. (1993) Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis. Br. J. Surg., 80, 1618-1619.
    • (1993) Br. J. Surg , vol.80 , pp. 1618-1619
    • Nugent, K.P.1
  • 3
    • 0027197062 scopus 로고
    • Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
    • Giardiello,F.M. et al. (1993) Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. N. Engl. J. Med., 328, 1313-1316.
    • (1993) N. Engl. J. Med , vol.328 , pp. 1313-1316
    • Giardiello, F.M.1
  • 4
    • 0029964295 scopus 로고    scopus 로고
    • Sulindac induced regression of colorectal adenomas in familial adenomatous polyposis: Evaluation of predictive factors
    • Giardiello,F.M. et al. (1996) Sulindac induced regression of colorectal adenomas in familial adenomatous polyposis: Evaluation of predictive factors. Gut, 38, 578-581.
    • (1996) Gut , vol.38 , pp. 578-581
    • Giardiello, F.M.1
  • 5
    • 0028850446 scopus 로고
    • Complete reversion and prevention of rectal adenomas in colectomized patients with familial adenomatous polyposis by rectal low-dose sulindac maintenance treatment: Advantages of a low-dose non steroidal anti-inflammatory drug regimen in reversing adenomas exceeding 33 months
    • Winde,G. et al. (1995) Complete reversion and prevention of rectal adenomas in colectomized patients with familial adenomatous polyposis by rectal low-dose sulindac maintenance treatment: Advantages of a low-dose non steroidal anti-inflammatory drug regimen in reversing adenomas exceeding 33 months. Dis. Colon Rectum, 38, 813-830.
    • (1995) Dis. Colon Rectum , vol.38 , pp. 813-830
    • Winde, G.1
  • 6
    • 0036177847 scopus 로고    scopus 로고
    • Long-term treatment with sulindac in familial adenomatous polyposis: A prospective cohort study
    • Cruz-Correa,M. et al. (2002) Long-term treatment with sulindac in familial adenomatous polyposis: A prospective cohort study. Gastroenterology, 122, 641-645.
    • (2002) Gastroenterology , vol.122 , pp. 641-645
    • Cruz-Correa, M.1
  • 7
    • 70849114163 scopus 로고    scopus 로고
    • Rectal epithelial apoptosis in familial adenomatous polyposis with sulindac
    • Keller,J.J. et al. (1999) Rectal epithelial apoptosis in familial adenomatous polyposis with sulindac. Gut, 45, 795-796.
    • (1999) Gut , vol.45 , pp. 795-796
    • Keller, J.J.1
  • 8
    • 0037018508 scopus 로고    scopus 로고
    • Primary chemoprevention of familial adenomatous polyposis with sulindac
    • Giardiello,F.M. et al. (2002) Primary chemoprevention of familial adenomatous polyposis with sulindac. N. Engl. J. Med., 346, 1054-1059.
    • (2002) N. Engl. J. Med , vol.346 , pp. 1054-1059
    • Giardiello, F.M.1
  • 9
    • 55549132996 scopus 로고    scopus 로고
    • Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: A randomized placebo-controlled, double-blind trial
    • Meyskens,F.L. et al. (2008) Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: A randomized placebo-controlled, double-blind trial. Cancer Prev. Res., 1 32-38.
    • (2008) Cancer Prev. Res , vol.1 , pp. 32-38
    • Meyskens, F.L.1
  • 10
    • 0028000576 scopus 로고
    • Adenocarcinoma in the rectal segment in familial polyposis coli is not prevented by sulindac therapy
    • Niv,Y. et al. (1994) Adenocarcinoma in the rectal segment in familial polyposis coli is not prevented by sulindac therapy. Gastroenterology, 107, 854-857.
    • (1994) Gastroenterology , vol.107 , pp. 854-857
    • Niv, Y.1
  • 11
    • 0028813830 scopus 로고
    • Rectal cancer after prolonged sulindac chemoprevention
    • Lynch,H.T. et al. (1995) Rectal cancer after prolonged sulindac chemoprevention. Cancer, 75, 936-938.
    • (1995) Cancer , vol.75 , pp. 936-938
    • Lynch, H.T.1
  • 12
    • 0032451393 scopus 로고    scopus 로고
    • Rectal cancer after sulindac therapy for a sporadic adenomatous colonic polyp
    • Matsubashi,N. et al. (1998) Rectal cancer after sulindac therapy for a sporadic adenomatous colonic polyp. Am. J. Gastroenterol., 93, 2261-2266.
    • (1998) Am. J. Gastroenterol , vol.93 , pp. 2261-2266
    • Matsubashi, N.1
  • 13
    • 0034041399 scopus 로고    scopus 로고
    • Long term treatment with sulindac in familial adenomatosis polyposis: Is there an actual efficacy in prevention of rectal cancer?
    • Tonelli,F. et al. (2000) Long term treatment with sulindac in familial adenomatosis polyposis: Is there an actual efficacy in prevention of rectal cancer? J. Surg. Oncol., 74, 15-20.
    • (2000) J. Surg. Oncol , vol.74 , pp. 15-20
    • Tonelli, F.1
  • 14
    • 9344257283 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis
    • Boolbol,S.K. et al. (1996) Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis. Cancer Res., 56, 2556-2560.
    • (1996) Cancer Res , vol.56 , pp. 2556-2560
    • Boolbol, S.K.1
  • 15
    • 0029739519 scopus 로고    scopus 로고
    • Sulindac suppresses tumorigenesis in the Min mouse
    • Beazer-Barclay,Y. et al. (1996) Sulindac suppresses tumorigenesis in the Min mouse. Carcinogenesis, 17, 1757-1760.
    • (1996) Carcinogenesis , vol.17 , pp. 1757-1760
    • Beazer-Barclay, Y.1
  • 16
    • 0030758925 scopus 로고    scopus 로고
    • Sulindac causes rapid regression of preexisting tumors in Min/+ mice independent of prostaglandin biosysnthesis
    • Chiu,C.H. et al. (1997) Sulindac causes rapid regression of preexisting tumors in Min/+ mice independent of prostaglandin biosysnthesis. Cancer Res., 57, 4267-4273.
    • (1997) Cancer Res , vol.57 , pp. 4267-4273
    • Chiu, C.H.1
  • 17
    • 0037360331 scopus 로고    scopus 로고
    • Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations
    • Yang,K. et al. (2003) Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations. Carcinogenesis, 24, 605-611.
    • (2003) Carcinogenesis , vol.24 , pp. 605-611
    • Yang, K.1
  • 19
    • 70849129227 scopus 로고    scopus 로고
    • Sulindac induces benign and malignant tumors with increased COX-2 expression in the proximal colon of normal C57Bl/6 mice
    • Yang,K. et al. (2005) Sulindac induces benign and malignant tumors with increased COX-2 expression in the proximal colon of normal C57Bl/6 mice. Proc. Am. Assoc. Cancer Res., 46, 1427.
    • (2005) Proc. Am. Assoc. Cancer Res , vol.46 , pp. 1427
    • Yang, K.1
  • 20
    • 0028567875 scopus 로고
    • A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors
    • Fodde,R. et al. (1994) A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proc. Natl Acad. Sci. USA, 91, 8969-8973.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 8969-8973
    • Fodde, R.1
  • 21
    • 0033559202 scopus 로고    scopus 로고
    • Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice
    • Edelmann,W. et al. (1999) Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice. Cancer Res., 59, 1301-1307.
    • (1999) Cancer Res , vol.59 , pp. 1301-1307
    • Edelmann, W.1
  • 22
    • 0037370137 scopus 로고    scopus 로고
    • Pathology of mouse models of intestinal cancer: Consensus report and recommendations
    • Boivin,G.P. et al. (2003) Pathology of mouse models of intestinal cancer: Consensus report and recommendations. Gastroenterology, 124, 762-777.
    • (2003) Gastroenterology , vol.124 , pp. 762-777
    • Boivin, G.P.1
  • 23
    • 70849089513 scopus 로고    scopus 로고
    • Sulindac rapidly induces inflammation and neoplasms in the intestine of A/J mice
    • Suzuki,K. et al. (2007) Sulindac rapidly induces inflammation and neoplasms in the intestine of A/J mice. Proc. Am. Assoc. Cancer Res. 48, 2007.
    • (2007) Proc. Am. Assoc. Cancer Res , vol.48 , pp. 2007
    • Suzuki, K.1
  • 24
    • 0027244454 scopus 로고
    • Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans
    • Bjarnason,I. et al. (1993) Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans. Gastroenterology, 104, 1832-1847.
    • (1993) Gastroenterology , vol.104 , pp. 1832-1847
    • Bjarnason, I.1
  • 25
    • 70349651858 scopus 로고    scopus 로고
    • Present status and strategy of NSAIDs-induced small bowel injury
    • epub ahead of print
    • Higuchi,K. et al. (2009) Present status and strategy of NSAIDs-induced small bowel injury. J. Gastroenterol. (epub ahead of print).
    • (2009) J. Gastroenterol
    • Higuchi, K.1
  • 26
    • 33644531928 scopus 로고    scopus 로고
    • Microbial flora in NSAID-induced intestinal damage: A role for antibiotics?
    • Lanas,A. et al. (2006) Microbial flora in NSAID-induced intestinal damage: A role for antibiotics? Digestion, 73 (suppl. 1), 136-150.
    • (2006) Digestion , vol.73 , Issue.SUPPL. 1 , pp. 136-150
    • Lanas, A.1
  • 27
    • 58849111794 scopus 로고    scopus 로고
    • Intestinal permeability in the pathogenesis of NSAID-induced enteropathy
    • Bjarnason,I. et al. (2009) Intestinal permeability in the pathogenesis of NSAID-induced enteropathy. J. Gastroenterol., 44 (suppl. XIX), 23-29.
    • (2009) J. Gastroenterol , vol.44 , Issue.SUPPL. XIX , pp. 23-29
    • Bjarnason, I.1
  • 28
    • 22344434243 scopus 로고    scopus 로고
    • Sulindac enhances the proteasome inhibitor bortezomib-mediated oxidative stress and anticancer activity
    • Minami,T. et al. (2005) Sulindac enhances the proteasome inhibitor bortezomib-mediated oxidative stress and anticancer activity. Clin. Cancer Res., 11, 5248-5256.
    • (2005) Clin. Cancer Res , vol.11 , pp. 5248-5256
    • Minami, T.1
  • 29
    • 33845760859 scopus 로고    scopus 로고
    • Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction
    • Seo,S.-K. et al. (2007) Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction. Apoptosis 12, 195-209.
    • (2007) Apoptosis , vol.12 , pp. 195-209
    • Seo, S.-K.1
  • 30
    • 33947545295 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and oxidative stress in cancer cells
    • Adachi,M. et al. (2007) Nonsteroidal anti-inflammatory drugs and oxidative stress in cancer cells. Histol. Histopathol., 22, 437-442.
    • (2007) Histol. Histopathol , vol.22 , pp. 437-442
    • Adachi, M.1
  • 31
    • 58949094558 scopus 로고    scopus 로고
    • Chemopreventive agents induce oxidative stress in cancer cells leading to COX-2 overexpression and COX-2 independent cell death
    • Sun,Y. et al. (2009) Chemopreventive agents induce oxidative stress in cancer cells leading to COX-2 overexpression and COX-2 independent cell death. Carcinogenesis, 30, 93-100.
    • (2009) Carcinogenesis , vol.30 , pp. 93-100
    • Sun, Y.1
  • 32
    • 0038352053 scopus 로고    scopus 로고
    • Radical causes of cancer
    • Hussain,S.P. et al. (2003) Radical causes of cancer. Nat. Rev. Cancer, 3, 276-285.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 276-285
    • Hussain, S.P.1
  • 33
    • 0036082617 scopus 로고    scopus 로고
    • Oxidative stress inactivates the human DNA mismatch repair system
    • Chang,C.L. et al. (2002) Oxidative stress inactivates the human DNA mismatch repair system. Am. J. Physiol. Cell Physiol., 283 148-154.
    • (2002) Am. J. Physiol. Cell Physiol , vol.283 , pp. 148-154
    • Chang, C.L.1
  • 34
    • 13944257829 scopus 로고    scopus 로고
    • 44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells
    • 44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells. Mol. Cancer Ther. 4, 51-59.
    • (2005) Mol. Cancer Ther , vol.4 , pp. 51-59
    • Sun, Y.1
  • 35
    • 0142026209 scopus 로고    scopus 로고
    • p38 MAP kinases: Key signaling molecules are therapeutic targets for inflammatory diseases
    • Kumar,S. et al. (2003) p38 MAP kinases: Key signaling molecules are therapeutic targets for inflammatory diseases. Nat. Rev. Drug Discov., 2, 717-726.
    • (2003) Nat. Rev. Drug Discov , vol.2 , pp. 717-726
    • Kumar, S.1
  • 36
    • 3342918498 scopus 로고    scopus 로고
    • The p38 MAP kinase pathway as a therapeutic target in inflammatory disease
    • Saklatvala,J. (2004) The p38 MAP kinase pathway as a therapeutic target in inflammatory disease. Curr. Opin. Pharmacol., 4, 372-377.
    • (2004) Curr. Opin. Pharmacol , vol.4 , pp. 372-377
    • Saklatvala, J.1
  • 37
    • 34547154349 scopus 로고    scopus 로고
    • P38 MAP-kinases pathway regulation, function and role in human diseases
    • Cuenda,A. et al. (2007) P38 MAP-kinases pathway regulation, function and role in human diseases. Biochim. Biophys. Acta, 1773, 1358-1375.
    • (2007) Biochim. Biophys. Acta , vol.1773 , pp. 1358-1375
    • Cuenda, A.1
  • 38
    • 63749083925 scopus 로고    scopus 로고
    • Targeting protein kinases for the development of anti-inflammatory drugs
    • Cohen,P. (2009) Targeting protein kinases for the development of anti-inflammatory drugs. Curr. Opin. Cell Biol., 21, 317-324.
    • (2009) Curr. Opin. Cell Biol , vol.21 , pp. 317-324
    • Cohen, P.1
  • 39
    • 47949096781 scopus 로고    scopus 로고
    • Cancer-related inflammation
    • Mantovani,A. et al. (2008) Cancer-related inflammation. Nature 454, 436-444.
    • (2008) Nature , vol.454 , pp. 436-444
    • Mantovani, A.1
  • 40
    • 65549157422 scopus 로고    scopus 로고
    • Inflammatory bowel disease: A model of chronic inflammation-induced cancer
    • Yang,G.Y. et al. (2009) Inflammatory bowel disease: A model of chronic inflammation-induced cancer. Methods Mol. Biol., 511 193-233.
    • (2009) Methods Mol. Biol , vol.511 , pp. 193-233
    • Yang, G.Y.1
  • 41
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability
    • Colotta,F. et al. (2009) Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability. Carcinogenesis, 30, 1061-1073.
    • (2009) Carcinogenesis , vol.30 , pp. 1061-1073
    • Colotta, F.1
  • 42
    • 0035206705 scopus 로고    scopus 로고
    • The role of mutant Apc in the development of dysplasia and cancer in the mouse model of dextran sulfate sodium-induced colitis
    • Cooper,H.S. et al. (2001) The role of mutant Apc in the development of dysplasia and cancer in the mouse model of dextran sulfate sodium-induced colitis. Gastroenterology, 121, 1407-1416.
    • (2001) Gastroenterology , vol.121 , pp. 1407-1416
    • Cooper, H.S.1
  • 43
    • 27944442806 scopus 로고    scopus 로고
    • Dextran sodium sulfate strongly promotes Iolorectal carcinogenesis in Apc (Min/+): Mice: inflammatory stimuli by dextran sodium sulfate results in the development of multiple colonic neoplasms
    • Tanaka,T. et al. (2006) Dextran sodium sulfate strongly promotes Iolorectal carcinogenesis in Apc (Min/+): Mice: inflammatory stimuli by dextran sodium sulfate results in the development of multiple colonic neoplasms. Int. J. Cancer, 118, 25-34.
    • (2006) Int. J. Cancer , vol.118 , pp. 25-34
    • Tanaka, T.1
  • 44
    • 33745118276 scopus 로고    scopus 로고
    • Induction of inflammatory bowel disease accelerates adenoma formation in Min+/- mice
    • Huang,E.H. et al. (2006) Induction of inflammatory bowel disease accelerates adenoma formation in Min+/- mice. Surgery, 139, 782-788.
    • (2006) Surgery , vol.139 , pp. 782-788
    • Huang, E.H.1


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