Effects of signal transducer and activator of transcription (STAT) genes STAT1 and STAT3 genotypic combinations on fertilization and embryonic survival rates in Holstein cattle

Journal of Dairy Science

Volumn 92, Issue 12, 2009, Pages 6186-6191

  Khatib, H ^a   Huang, W ^a   Mikheil, D ^a   Schutzkus, V ^a   Monson, R L ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Dairy cow; Fertility; Gene gene interaction; Survival rate

Indexed keywords

BOS;

EID: 70749137289     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2009-2439     Document Type: Article

References (21)

1. Carlborg, O., and C. S. Haley. 2004. Epistasis: Too often neglected in complex trait studies? Nat. Rev. Genet. 5:618-625.
2. Cobanoglu, O., I. Zaitoun, Y. M. Chang, G. E. Shook, and H. Khatib. 2006. Effects of the signal transducer and activator of transcription 1 (STAT1) gene on milk production traits in Holstein dairy cattle. J. Dairy Sci. 89:4433-4437.
3. Darnell, J. E. 1997. STATs and gene regulation. Science 277:1630-1635.
4. Dobson, H., S. L. Walker, M. J. Morris, J. E. Routly, and R. F. Smith. 2008. Why is it getting more difficult to successfully artificially inseminate dairy cows? Animal 2:1104-1111.
5. Hombría, J. C., and S. Brown. 2002. The fertile field of Drosophila Jak/STAT signalling. Curr. Biol. 12:R569-R575.
6. Khatib, H., W. Huang, X. Wang, A. H. Tran, A. B. Bindrim, V. Schutzkus, R. L. Monson, and B. S. Yandell. 2009. Single gene and gene interaction effects on fertilization and embryonic survival rates in cattle. J. Dairy Sci. 92:2238-2247.
7. Khatib, H., C. Maltecca, R. L. Monson, V. Schutzkus, X. Wang, and J. J. Rutledge. 2008b. The fibroblast growth factor 2 gene is associated with embryonic mortality in cattle. J. Anim. Sci. 86:2063-2067.
8. Khatib, H., R. L. Monson, V. Schutzkus, D. M. Kohl, G. J. Rosa, and J. J. Rutledge. 2008a. Mutations in the STAT5A gene are associated with embryonic survival and milk composition in cattle. J. Dairy Sci. 91:784-793.
9. Kisseleva, T., S. Bhattacharya, J. Braunstein, and C. W. Schindler. 2002. Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene 285:1-24.
10. Kodama, H., K. Fukuda, J. Pan, S. Makino, A. Baba, S. Hori, and S. Ogawa. 1997. Leukemia inhibitory factor, a potent cardiac hypertrophic cytokine, activates the JAK/STAT pathway in rat cardiomyocytes. Circ. Res. 81:656-663.
11. Maj, T., and A. Chelmonska-Soyta. 2007. Pleiotropy and redundancy of STAT proteins in early pregnancy. Reprod. Domest. Anim. 42:343-353.
12. McCullagh, P., and J. A. Nelder. 1989. Generalized Linear Models. 2nd ed. Chapman and Hall, London, UK.
13. Morris, D., and M. Diskin. 2008. Effect of progesterone on embryo survival. Animal 2:1112-1119.
14. R Development Core Team. 2008. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria. www.R-project.org.
15. Royal, M., G. E. Mann, and A. P. Flint. 2000. Strategies for reversing the trend towards subfertility in dairy cattle. Vet. J. 160:53-60.
16. Santos, J. E. P., W. W. Thatcher, R. C. Chebel, R. L. A. Cerri, and K. N. Galvao. 2004. The effect of embryonic death rates in cattle on the efficacy of estrus synchronization programs. Anim. Reprod. Sci. 83:513-535.
17. Shook, G. E. 2006. Major advances in determining appropriate selection goals. J. Dairy Sci. 89:1349-1361.
18. Takeda, K., K. Noguchi, W. Shi, T. Tanaka, M. Matsumoto, N. Yoshida, T. Kishimoto, and S. Akira. 1997. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc. Natl. Acad. Sci. USA 94:3801-3804.
19. Teglund, S., C. McKay, E. Schuetz, J. M. van Deursen, D. Stravopodis, D. Wang, M. Brown, S. Bodner, G. Grosveld, and J. N. Ihle. 1998. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell 93:841-850.
20. Truchet, S., M. Chebrout, C. Djediat, J. Wietzerbin, and P. Debey. 2004. Presence of permanently activated signal transducers and activators of transcription in nuclear interchromatin granules of unstimulated mouse oocytes and preimplantation embryos. Biol. Reprod. 71:1330-1339.
21. VanRaden, P. M., A. H. Sanders, M. E. Tooker, R. H. Miller, H. D. Norman, M. T. Kuhn, and G. R. Wiggans. 2004. Development of a national genetic evaluation for cow fertility. J. Dairy Sci. 87:2285-2292.