Preparation, characterization, transfection efficiency, and cytotoxicity of liposomes containing oligoamine-modified cholesterols as nanocarriers to Neuro2A cells

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 5, Issue 4, 2009, Pages 457-462

  Malaekeh Nikouei, Bizhan ^a   Malaekeh Nikouei, Mohammad ^b   Oskuee, Reza Kazemi ^a   Ramezani, Mohammad ^a  

^a MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Cytotoxicity; Nanoliposome; Oligoamine; Transfection

Indexed keywords

CATIONIC LIPIDS; CATIONIC LIPOSOMES; CYTOTOXIC; GENE DELIVERY SYSTEMS; HEAD GROUPS; LARGE UNILAMELLAR VESICLES; LIPOPLEXES; MULTILAMELLAR VESICLES; NANOCARRIERS; PLASMID DNA; POLYCARBONATE FILTERS; RENILLA LUCIFERASE; SYNTHESIZED DERIVATIVES; TRANSFECTION ACTIVITY; TRANSFECTION EFFICIENCY;

AMINES; CHOLESTEROL; CYTOTOXICITY; DNA; FLUORINE CONTAINING POLYMERS; GENE TRANSFER; GENES; LIPOSOMES; PHOSPHOLIPIDS; SUGAR (SUCROSE); SYNCHROTRONS;

NUCLEIC ACIDS;

CHOLESTEROL; LIPOSOME; NANOCARRIER; RENILLA LUCIFERIN 2 MONOOXYGENASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA TRANSFECTION; DNA TRANSFER; GENE DELIVERY SYSTEM; GENETIC CODE; GENETIC TRANSFECTION; MOUSE; NONHUMAN; SYNTHESIS;

AMINES; ANIMALS; CELL DEATH; CELL LINE, TUMOR; CHOLESTEROL; DRUG CARRIERS; ESTERS; ETHIDIUM; HUMANS; LIPOSOMES; MICE; NANOSTRUCTURES; PARTICLE SIZE; TRANSFECTION;

RENILLA LUCIFERASE;

EID: 70749109999     PISSN: 15499634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nano.2009.02.001     Document Type: Article

References (25)

1. Luo D., and Saltzman W.M. Synthetic DNA delivery systems. Nat Biotechnol. 18 (2000) 33-37
2. El-Aneed A. An overview of current delivery systems in cancer gene therapy. J Control Release. 94 (2004) 1-14
3. Patil S.D., Rhodes D.G., and Burgess D.J. DNA-based therapeutics and DNA delivery systems: a comprehensive review. AAPS J. 7 (2005) E61-77
4. Simoes S., Filipe A., Feneca H., Mano M., Penacho N., Duzgunes N., et al. Cationic liposomes for gene delivery. Expert Opin Drug Deliv. 2 (2005) 237-254
5. Ropert C. Liposomes as a gene delivery system. Braz J Med Biol Res. 32 (1999) 163-169
6. Hart S.L. Lipid carriers for gene therapy. Curr Drug Deliv. 2 (2005) 423-428
7. Martin B., Sainlos M., Aissaoui A., Oudrhiri N., Hauchecorne M., Vigneron J.P., et al. The design of cationic lipids for gene delivery. Curr Pharm Design. 11 (2005) 375-394
8. Wasungu L., and Hoekstra D. Cationic lipids, lipoplexes and intracellular delivery of genes. J Control Release. 116 (2006) 255-264
9. Lechardeur D., Verkman A.S., and Lukacs G.L. Intracellular routing of plasmid DNA during non-viral gene transfer. Adv Drug Deliv Rev. 57 (2005) 755-767
10. Gao X., and Huang L. A novel cationic liposome reagent for efficient transfection of mammalian cells. Biochem Biophys Res Commun. 179 (1991) 280-285
11. Moradpour D., Schauer J.I., Zurawski V.R., Wands J.R., and Boutin R.H. Efficient gene transfer into mammalian cells with cholesteryl-spermidine. Biochem Biophys Res Commun. 221 (1996) 82-88
12. Gao H., and Hui K.M. Synthesis of a novel series of cationic lipids that can act as efficient gene delivery vehicles through systematic heterocyclic substitution of cholesterol derivatives. Gene Ther. 8 (2001) 855-863
13. Behr J. Synthetic gene transfer vectors. Pure Appl Chem. 66 (1994) 827-835
14. Takeuchi K., Ishihara M., Kawaura C., Noji M., Furuno T., and Nakanishi M. Effect of zeta potential of cationic liposomes containing cationic cholesterol derivatives on gene transfection. FEBS Lett. 397 (1996) 207-209
15. Kawaura C., Noguchi A., Furuno T., and Nakanishi M. Atomic force microscopy for studying gene transfection mediated by cationic liposomes with a cationic cholesterol derivative. FEBS Lett. 421 (1998) 69-72
16. Kawakami S., Yamashita F., Nishikawa M., Takakura Y., and Hashida M. Asialoglycoprotein receptor-mediated gene transfer using novel galactosylated cationic liposomes. Biochem Biophys Res Commun. 252 (1998) 78-83
17. Meyer M., Zintchenko A., Ogris M., and Wagner E. A dimethylmaleic acid-melittin-polylysine conjugate with reduced toxicity, pH-triggered endosomolytic activity and enhanced gene transfer potential. J Gene Med. 9 (2007) 797-805
18. Malaekeh-Nikouei B., Jaafari M.R., Sajadi S.A., and Samiee A. The enhancement of immunosuppressive effects of cyclosporine A on human T-cells using fusogenic liposomes. Colloid Surface B. 67 (2008) 238-244
19. Spelios M., and Savva M. Novel N,N′-diacyl-1,3-diaminopropyl-2-carbamoyl bivalent cationic lipids for gene delivery-synthesis, in vitro transfection activity, and physicochemical characterization. FEBS J. 275 (2008) 148-162
20. Geall A.J., and Blagbrough I.S. Rapid and sensitive ethidium bromide fluorescence quenching assay of polyamine conjugate-DNA interactions for the analysis of lipoplex formation in gene therapy. J Pharm Biomed Anal. 22 (2000) 849-859
21. Elouahabi A., and Ruysschaert J. Formation and intracellular trafficking of lipoplexes and polyplexes. Mol Ther. 11 (2004) 336-347
22. Ross P.C., and Hui S.W. Lipoplex size is a major determinant of in vitro lipofection efficiency. Gene Ther. 6 (1999) 651-659
23. MacDonald R.C. Small-volume extrusion for preparation of large unilamellar vesicles. Biochim Biophys Acta. 1061 (1991) 297-303
24. Goncalves E., Debs R.J., and Heath T.D. The effect of liposome size on the final lipid/DNA ratio of cationic lipoplexes. Biophys J. 86 (2004) 1554-1563
25. Duncan R., and Sat Y.N. Tumour targeting by enhanced permeability and retention (EPR) effect. Ann Oncol. 9 Suppl 2 (1998) 39