Is Human Herpesvirus-8 Transmitted by Transfusion?

Transfusion Medicine Reviews

Volumn 24, Issue 1, 2010, Pages 1-14

  Vamvakas, Eleftherios C ^a  

^a Cedars Sinai Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BLOOD DONOR; BLOOD TRANSFUSION; CHILD HEALTH; CROSS-SECTIONAL STUDY; GEOGRAPHIC DISTRIBUTION; HERPES VIRUS INFECTION; HUMAN; HUMAN HERPESVIRUS 8; NONHUMAN; NORTH AMERICA; RISK ASSESSMENT; RISK FACTOR; SEROCONVERSION; SEROPREVALENCE; UGANDA; VIRUS REACTIVATION; VIRUS TRANSMISSION;

AFRICA; BLOOD TRANSFUSION; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 8, HUMAN; HUMANS; INCIDENCE; TISSUE DONORS; UNITED STATES;

EID: 70749086434     PISSN: 08877963     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tmrv.2009.09.001     Document Type: Article

References (90)

1. Cannon M.J., Laney A.S., and Pellett P.E. Human herpesvirus 8: Current issues. Clin Infect Dis 37 (2003) 82-87
2. Blackbourn D.J., Ambroziak J., Lennette E., et al. Infectious human herpesvirus 8 in a healthy North-American blood donor. Lancet 349 (1997) 609-611
3. Vamvakas E.C., and Tegtmeier G.E. Herpes viruses. In: Barbara J.A.J., Regan F.A.M., and Contreras M.C. (Eds). Transfusion microbiology (2008), Cambridge University Press, Cambridge, UK 35-58
4. Sitas F., Carrara H., Beral V., et al. Antibodies against human herpesvirus 8 in South African patients with cancer. N Engl J Med 340 (1999) 1863-1871
5. Chang Y., Ziegler J., Wabinga H., et al. Kaposi's sarcoma-associated herpesvirus and Kaposi's sarcoma in Africa. Arch Intern Med 156 (1996) 202-204
6. Olsen S.J., Chang Y., Moore P.S., et al. Increasing Kaposi's sarcoma-associated herpesvirus seroprevalence with age in a highly Kaposi's sarcoma endemic region, Zambia in 1985. AIDS 12 (1998) 1921-1925
7. Elton M.A., Mbulaiteye S.M., Dada A.J., et al. Transmission of human herpesvirus 8 by sexual activity among adults in Lagos, Nigeria. AIDS 16 (2002) 2473-2478
8. Cattani P., Cerimele F., Porta D., et al. Age-specific seroprevalence of human herpesvirus-8 in Mediterranean regions. Clin Microbiol Infect 9 (2008) 274-279
9. Calabro M.L., Sheldon J., Favero A., et al. Seroprevalence and Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 in several regions of Italy. J Hum Virol 1 (1998) 207-213
10. Zavitsanou A., Sypsa V., Petrodaskalaki M., et al. Human herpesvirus 8 (HHV-8) infection in healthy urban employees from Greece: Seroprevalence and associated factors. J Med Virol 79 (2007) 591-596
11. Iscovich J., Fischbein A., Fisher-Fischbein J., et al. Seroprevalence of Kaposi's sarcoma-associated herpesvirus in healthy adults in Israel. Anticancer Res 20 (2000) 2119-2122
12. Gambus G., Bourboulia D., Esteve A., et al. Prevalence and distribution of HHV-8 in different subpopulations with and without HIV infection in Spain. AIDS 15 (2001) 1167-1174
13. Schinaia N., Kodra Y., Sarmati L., et al. Prevalence of HHV-8 infection in Albanian adults and association with HBV and HCV. Eur J Epidemiol 19 (2004) 467-469
14. Challine D., Roudot-Troraval F., Sarah T., et al. Seroprevalence of human herpesvirus 8 antibody in populations at high or low risk of transfusion, graft, or sexual transmission of viruses. Transfusion 41 (2001) 1120-1125
15. Pellett P.E., Wright D.J., Engels E.A., et al. Multicenter comparison of serologic assays and estimation of human herpesvirus 8 seroprevalence among US blood donors. Transfusion 43 (2003) 1260-1268
16. Ferreira S., Sanabani S., Reis A.D., et al. Human herpesvirus type 8 among Brazilian blood donors. Transfusion 43 (2003) 1764-1765
17. Belec L., Cancre N., Hallouin M.C., et al. High prevalence in Central Africa of blood donors who are potentially infectious for human herpesvirus 8. Transfusion 38 (1998) 771-775
18. Enbom M., Urassa W., Massambu C., et al. Detection of human herpesvirus 8 DNA in serum from blood donors with HHV-8 antibodies indicates possible bloodborne virus transmission. J Med Virol 68 (2002) 264-267
19. Hudnall S.D., Chen T., Rady P., et al. Human herpesvirus 8 seroprevalence and viral load in healthy adult blood donors. Transfusion 43 (2003) 85-90
20. Mbulaiteye S.M., Biggar R.J., Bakaki P.M., et al. Human herpesvirus 8 infection and transfusion history in children with sickle-cell disease in Uganda. J Natl Cancer Inst 95 (2003) 1330-1335
21. Cottoni F., Santarelli R., Gentile G., et al. High rate of human herpesvirus-8 seroprevalence in thalassemic patients in Italy. J Clin Virol 30 (2004) 106-109
22. Lefrere J.J., Mariotti M., Girot R., et al. Transfusional risk of HHV-8 infection. Lancet 350 (1997) 217
23. Marcelin A.G., Apetrei C., Dupin N., et al. Parenteral transmission of Kaposi's sarcoma-associated herpesvirus. AIDS 12 (1998) 2351
24. Cannon M.J., Dollard S.C., Smith D.K., et al. Blood-borne and sexual transmission of human herpesvirus 8 in women with or at risk for human immunodeficiency virus infection. N Engl J Med 344 (2001) 637-643
25. Goedert J.J., Charurat M., Blattner W.A., et al. Risk factors for Kaposi's sarcoma-associated herpes virus infection among HIV-1-infected pregnant women in the USA. AIDS 17 (2003) 425-433
26. Bagni R., and Whitby D. Kaposi's sarcoma-associated herpesvirus transmission and primary infection. Curr Opin HIV AIDS 4 (2009) 22-26
27. Operskalski E.A., Busch M.P., Mosley J.W., et al. Blood donations and viruses. Lancet 349 (1997) 1327
28. Engels E.A., Eastman H., Ablashi D.V., et al. Risk of transfusion-associated transmission of human herpesvirus 8. J Natl Cancer Inst 91 (1999) 1773-1775
29. Dollard S.C., Nelson K.E., Ness P.M., et al. Possible transmission of human herpesvirus 8 by blood transfusion in a historical United States cohort. Transfusion 45 (2005) 500-503
30. Hladik W., Dollard S.C., Mermin J., et al. Transmission of human herpesvirus 8 by blood transfusion. N Engl J Med 355 (2006) 1331-1338
31. Cannon M.J., Operskalski E.A., Mosley J.W., et al. Lack of evidence for human herpesvirus-8 transmission via blood transfusion in a historical United States cohort. J Infect Dis 199 (2009) 1592-1598
32. Dodd R.Y. Human herpesvirus 8: What (not) to do?. Transfusion 45 (2005) 463-465
33. Blajchman M.A., and Vamvakas E.C. The continuing risk of transfusion-transmitted infections. N Engl J Med 355 (2006) 1303-1305
34. Lefrere J.J., Guillaume N., and Laperche S. Should cellular therapy products be tested for human herpesvirus 8?. Transfusion 47 (2007) 1550
35. Moore P.S., Chang Y., and Jaffe H.W. Transmission of human herpesvirus 8 by blood transfusion. N Engl J Med 356 (2007) 88
36. Busch M., and Glynn S. Use of blood-donor and transfusion-recipient biospecimen repositories to address emerging blood-safety concerns and advance infectious disease research: The National Heart, Lung, and Blood Institute Biologic Specimen Repository. J Infect Dis 199 (2009) 1564-1566
37. de Souza V.A., Sumita L.M., Nascimento M.C., et al. Human herpesvirus-8 infection and oral shedding in Amerindian and non-Amerindian populations in the Brazilian Amazon region. J Infect Dis 196 (2007) 844-852
38. Biggar R.J., Whitby D., Marshall V., et al. Human herpesvirus 8 in Brazilian Amerindians: A hyperendemic population with a new subtype. J Infect Dis 181 (2000) 1562-1568
39. Mohanna S., Maco V., Bravo F., et al. Epidemiology and clinical characteristics of classic Kaposi's sarcoma, seroprevalence, and variants of human herpesvirus 8 in South America: A critical review of an old disease. Int J Infect Dis 9 (2005) 239-250
40. Alkharsah K.R., Dedicoat M., Blasczyk R., et al. Influence of HLA alleles on shedding of Kaposi sarcoma-associated herpesvirus in saliva in an African population. J Infect Dis 195 (2007) 809-816
41. Whitby D., Marshall V.A., Bagni R.K., et al. Reactivation of Kaposi's sarcoma-associated herpesvirus by natural products from Kaposi's sarcoma endemic regions. Int J Cancer 120 (2007) 321-328
42. Mbulaiteye S.M., Biggar R.J., Pfeiffer R.M., et al. Water, socioeconomic factors, and human herpesvius 8 infection in Ugandan children and their mothers. J Acquir Immune Defic Syndr 38 (2005) 474-479
43. Whitby D., Luppi M., Sabin C., et al. Detection of antibodies to human herpesvirus 8 in Italian children: Evidence of horizontal transmission. Br J Cancer 82 (2000) 702-704
44. Malope B.I., Pfeiffer R.M., Mbisa G., et al. Transmission of Kaposi sarcoma-associated herpesvirus between mothers and children in a South African population. J Acquir Immune Defic Syndr 44 (2007) 351-355
45. Minhas V., Crabtree K.L., Chao A., et al. Early childhood infection by human herpesvirus 8 in Zambia and the role of human immunodeficiency virus type 1 coinfection in a highly endemic area. Am J Epidemiol 168 (2008) 311-320
46. Mbulaiteye S.M., Pfeiffer R.M., Dolan B., et al. Seroprevalence and risk factors for human herpesvirus 8 infection, rural Egypt. Emerg Infect Dis 14 (2008) 586-591
47. Bourboulia D., Whitby D., Boshoff C., et al. Serologic evidence for mother-to-child transmission of Kaposi sarcoma-associated herpesvirus infection. JAMA 280 (1998) 31-32
48. Mayama S., Cuevas L.E., Sheldon J., et al. Prevalence and transmission of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in Ugandan children and adolescents. Int J Cancer 77 (1998) 817-820
49. Angeloni A., Heston L., Uccini S., et al. High prevalence of antibodies to human herpesvirus 8 in relatives of patients with classic Kaposi's sarcoma from Sardinia. J Infect Dis 177 (1998) 1715-1718
50. Plancoulaine S., Abel L., van Beveren M., et al. Human herpesvirus 8 transmission from mother to child and between siblings in an endemic population. Lancet 356 (2000) 1062-1065
51. Brayfield B.P., Kankasa C., West J.T., et al. Distribution of Kaposi-sarcoma associated herpesvirus/human herpesvirus 8 in maternal saliva and breast milk in Zambia: Implications for transmission. J Infect Dis 189 (2004) 2260-2270
52. Mantina H., Kankasa C., Klaskala W., et al. Vertical transmission of Kaposi's sarcoma-associated herpesvirus. Int J Cancer 94 (2001) 749-752
53. Martro E., Bultreys M., Stewart J.A., et al. Comparison of human herpesvirus 8 and Epstein-Barr virus seropositivity among children in areas endemic and non-endemic for Kaposi's sarcoma. J Med Virol 72 (2004) 126-131
54. Mbulaiteye S.M., Pfeiffer R.M., Whitby D., et al. Human herpesvirus 8 infection within families in rural Tanzania. J Infect Dis 187 (2003) 1780-1785
55. Plancoulaine S., Abel L., Trégouët D., et al. Respective roles of serological status and blood specific antihuman herpesvirus-8 antibody levels in human herpesvirus-8 intrafamilial transmission in a highly endemic area. Cancer Res 64 (2004) 8782-8787
56. Mbulaiteye S., Marshall V., Bagni R.K., et al. Molecular evidence for mother-to-child transmission of Kaposi sarcoma-associated herpesvirus in Uganda and K1 gene evolution within the host. J Infect Dis 193 (2006) 1250-1257
57. Dukers N.H.T.M., and Rezza G. Human herpesvirus 8 epidemiology: What we do and do not know. AIDS 17 (2003) 1717-1730
58. Engels E.A., Atkinson J.O., Graubard B.I., et al. Risk factors for human herpesvirus-8 infection among adults in the United States and evidence for sexual transmission. J Infect Dis 196 (2007) 199-207
59. Malope B.I., MacPhail P., Mbissa G., et al. No evidence of sexual transmission of Kaposi's sarcoma herpesvirus in a heterosexual South African population. AIDS 22 (2008) 519-526
60. Martin J.N., Ganen D.E., Osmond D.H., et al. Sexual transmission and the natural history of human herpesvirus 8 infection. N Engl J Med 338 (1998) 948-954
61. Smith N.A., Sabin C.A., Gopal R., et al. Serologic evidence of human herpesvirus 8 transmission by homosexual but not heterosexual men. J Infect Dis 180 (1999) 600-606
62. Martin J.N., and Osmond D.H. Determining specific sexual practices associated with human herpesvirus 8 transmission. Am J Epidemiol 151 (2000) 225-229
63. Grulich A.E., Cunningham P., Munier M.L., et al. Sexual behavior and human herpesvirus infection in homosexual men in Australia. Sex Health 2 (2005) 13-18
64. Martro E., Esteve A., Schultz T.F., et al. Risk factors for human herpesvirus 8 infection and AIDS-associated Kaposi's sarcoma among men who have sex with men in a European multicenter study. Int J Cancer 120 (2007) 1129-1135
65. Belec L., Tevi-Benissan C., Mohamed A.S., et al. Enhanced detection of human herpesvirus 8 and cytomegalovirus in semen of HIV-seropositive asymptomatic heterosexual men living in Central Africa. AIDS 12 (1998) 674-676
66. Taylor M.M., Chohan B., Lavreys L., et al. Shedding of human herpesvirus 8 in oral and genital secretions from HIV-1-seropositive and seronegative Kenyan women. J Infect Dis 190 (2004) 484-488
67. Pauk J., Huang M.L., Brodie S.J., et al. Mucosal shedding of human herpesvirus 8 in men. N Engl J Med 343 (2000) 1369-1377
68. Martin J.N. Diagnosis and epidemiology of human herpesvirus 8 infection. Semin Hematol 40 (2003) 133-142
69. Atkinson J., Edlin B.R., Engels E.A., et al. Seroprevalence of human herpesvirus 8 among injection drug users in San Francisco. J Infect Dis 187 (2003) 974-981
70. Jenkins F.J., Hoffman L.J., and Liegey-Dougall A. Reactivation of and primary infection with human herpesvirus-8 among solid-organ transplant recipients. J Infect Dis 185 (2002) 1238-1243
71. Luppi M., Barozzi P., Santagostino G., et al. Molecular evidence of organ-related transmission of Kaposi sarcoma-associated herpesvirus or human herpesvirus 8 in transplant patients. Blood 96 (2000) 3279-3281
72. Barozzi P., Luppi M., Facchetti F., et al. Post-transplant Kaposi's sarcoma lesions from renal transplant recipients barcoded either genetic or antigenic markers of the matched donors. Nat Med 9 (2003) 554-561
73. Pfeiffer R.M., Mbulaiteye S., and Engels E. A model to estimate risk of infection with human herpesvirus 8 associated with transfusion from cross-sectional data. Biometrics 60 (2004) 249-256
74. Ho M. Epidemiology of cytomegalovirus infections. Rev Infect Dis 12 Suppl. 7 (1990) S701-S710
75. Adler S.P., and McVoy M.M. Cytomegalovirus infections in seropositive patients after transfusion: The effect of red-cell storage and volume. Transfusion 29 (1989) 667-671
76. Roujeau J.C., Brun-Buisson C., Penso D., et al. Non-acquired immune deficiency syndrome-related Kaposi's sarcoma after severe infection. J Am Acad Dermatol 18 (1988) 378
77. Friedman Kien A.E., Saltzman B.R., Cao Y., et al. Kaposi's sarcoma in HIV-negative homosexual men. Lancet 355 (1990) 168-169
78. Bendsoe N., Dictor M., Blomberg J., et al. Increased incidence of Kaposi sarcoma in Sweden before the AIDS epidemic. Eur J Cancer 26 (1990) 699-702
79. Velez-Garcia E., Robles-Cardona N., and Fradera J. Kaposi's sarcoma in transfusion-associated AIDS. N Engl J Med 312 (1985) 648
80. Cockerill F.R., Hurley D., and Miglagelada J.R. Polymicrobial cholangitis and Kaposi's sarcoma in blood product transfusion-related acquired immune deficiency syndrome. Am J Med 80 (1986) 1237-1241
81. Padilla S., Rivera-Perlman Z., and Solomon L. Kaposi's sarcoma in transfusion-related acquired immunodeficiency syndrome. Arch Pathol Lab Med 114 (1990) 40-42
82. Aboulafia D., Mathisen G., and Mitsuyasu R. Case-report: Aggressive Kaposi's sarcoma and Campylobacter bacteremia in a female with transfusion-associated AIDS. Am J Med Sci 301 (1991) 256-258
83. Vamvakas E. Why are men who have had sex with men even once since 1977 indefinitely deferred from donating blood?. Transfusion 49 (2009) 1037-1042
84. Vamvakas E.C. Scientific background on the risk engendered by reducing the lifetime blood donation deferral period for men who have sex with men. Transf Med Rev 23 (2009) 85-102
85. Qu L., Xu S., Rowe D., et al. Efficacy of Epstein-Barr virus removal by leukoreduction of red blood cells. Transfusion 45 (2005) 591-595
86. Alfieri C., Tanner J., Carpenter L., et al. EBV transmission from a blood donor to an organ-transplant recipient with recovery of the same virus strain from the recipient blood and oropharynx. Blood 87 (1996) 812-817
87. Tattevin P., Cremieux A.C., Descamps D., et al. Transfusion-related infectious mononucleosis. Scand J Infect Dis 34 (2002) 777-778
88. Pearson H.A., Wood C., Andeman W., et al. Low risk of hepatitis B from blood transfusions in thalassemic patients in Connecticut. J Pediatr 108 (1986) 252-253
89. Papaevangelou G., Economidou J., Roumeliotou A., et al. Epstein-Barr infection in polytransfused patients with homozygous beta-thalassemia. Vox Sang 37 (1979) 305-309
90. Henle W., and Henle G. Epstein-Barr virus and blood transfusions. In: Dodd R.Y., and Barker L.F. (Eds). Infection, Immunity, and Blood Transfusion (1985), Alan R. Liss, New York, NY 201-209