Scientific Background on the Risk Engendered by Reducing the Lifetime Blood Donation Deferral Period for Men Who Have Sex With Men

Transfusion Medicine Reviews

Volumn 23, Issue 2, 2009, Pages 85-102

  Vamvakas, Eleftherios C ^a  

^a Cedars Sinai Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD DONOR; BLOOD TRANSFUSION; DISEASE TRANSMISSION; HETEROSEXUALITY; HUMAN; HUMAN HERPESVIRUS 8; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; INFECTION RISK; REVIEW; RISK ASSESSMENT; SEXUAL BEHAVIOR; THROMBOCYTE TRANSFUSION; TIME; VIRUS TRANSMISSION;

BLOOD DONORS; BLOOD TRANSFUSION; HEALTH POLICY; HERPESVIRIDAE INFECTIONS; HIV INFECTIONS; HOMOSEXUALITY, MALE; HUMANS; MALE; RISK; SEXUAL BEHAVIOR; UNITED STATES; UNSAFE SEX;

EID: 62449315034     PISSN: 08877963     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tmrv.2008.12.007     Document Type: Review

References (69)

1. Gayle H. An overview of the global HIV/AIDS epidemic with a focus on the United States. AIDS 14 Suppl.2 (2000) S8-S17
2. Centres for Disease Control and Prevention (CDC). HIV incidence among young men who have sex with men-Seven U.S. cities, 1994-2000. MMWR Morb Mortal Wkly Rep 50 (2001) 440-444
3. Valleroy L.A., Mackellar D.A., Karon J.M., et al. HIV prevalence and associated risks in young men who have sex with men. JAMA 284 (2000) 198-204
4. Schwarcz S.K., Kellogg T.A., McFarland W., et al. Characterization of sexually-transmitted disease clinic patients with recent human immunodeficiency virus infection. J Infect Dis 186 (2002) 1019-1022
5. Centres for Disease Control and Prevention (CDC). Trends in HIV/AIDS diagnoses among men who have sex with men-33 states, 2001-2006. MMWR Morb Mortal Wkly Rep 57 (2008) 681-686
6. PHLS, DHSS & PS, and and the Scottish ISD (D) 5 Collaborative Group. Trends in sexually-transmitted infections in the United Kingdom, 1990-1999 (2000), Public Health Laboratory Service, London, UK
7. Klausner J.D., Kent C.K., Wong W., et al. The public health response to epidemic syphilis, San Francisco, 1999-2004. Sex Transm Dis 32 Suppl.10 (2005) S11-S18
8. Brunt L.J., Bukasa A., Davison K.L., et al. Increase in recently-acquired syphilis infections in English, Welsh and Northern Irish blood donors. Vox Sang 93 (2007) 14-26
9. Dodds J., Nardonne A., Mercey D., et al. Increase in high-risk sexual behavior among homosexual men, London 1996-8: Cross-sectional, questionnaire study. BMJ 320 (2000) 1510
10. Leiss W., Tyshenko M., and Krewski D. Men-having-sex-with-men donor-deferral risk assessment: An analysis using risk management principles. Transf Med Rev 22 (2008) 35-57
11. US Food and Drug Administration Workshop on Behavior-Based Donor Deferrals in the NAT Era. March 8-9, 2006; Lister Hill Auditorium National Institutes of Health, Bethesda, MD.
12. Centers for Disease Control (CDC). Current trends in prevention of acquired immune deficiency syndrome (AIDS): Report of inter-agency recommendations. MMWR Morb Mortal Wkly Rep 32 (1983) 101-103
13. Department of Health and Human Services, Public Health Service, Food and Drug Administration. Revised recommendations for the prevention of human immunodeficiency virus (HIV) transmission by blood and blood products (1992), Food and Drug Administration, Bethesda, MD
14. Soriano V., Dronda F., Gonzales-Lopez A., et al. HIV-1 causing AIDS and death in a seronegative individual. Vox Sang 67 (1994) 410-411
15. Coutlee F., Olivier C., Cassol S., et al. Absence of prolonged immunosilent infection with human immunodeficiency virus in individuals with high-risk behaviors. Am J Med 96 (1994) 42-48
16. Centers for Disease Control and Prevention (CDC). Persistent lack of detectable HIV-1 antibody in a person with HIV infection - Utah, 1995. MMWR Morb Mortal Wkly Rep 45 (1995) 181-185
17. Busch M.P., Glynn S.A., Stramer S.L., et al. A new strategy for estimating risks of transfusion-transmitted viral infections based on rates of detection in recently-infected donors. Transfusion 45 (2005) 254-264
18. Busch M.P., Lee L.L., Satten G.A., et al. Time-course of detection of viral and serological markers preceding HIV-1 seroconversion: Implications for blood and tissue donor screening. Transfusion 35 (1995) 91-97
19. AABB, America's Blood Centers, and American Red Cross. Deferral policy regarding males who have had sex with males (MSM) (January 2008). Joint position statement. Available at:. http://www.aabb.org/Content/News_and_Media/Statements/statement013108.ht m Last accessed May 20, 2008
20. Sanchez A.M., Schreiber G.B., Nass C.C., et al. The impact of male-to-male sexual experience on risk-profiles of blood donors. Transfusion 45 (2005) 404-413
21. Ward J.W., Kleinman S.H., Douglas D.K., et al. Epidemiologic characteristics of blood donors with antibody to human immunodeficiency virus. Transfusion 28 (1988) 298-301
22. Doll L.S., Petersen L.R., White C.R., et al. Human immunodeficiency virus type-1-infected blood donors: Behavioral characteristics and reasons for donation. The HIV Blood Donor Study Group. Transfusion 31 (1991) 704-709
23. Lefrere J.J., Elghouzzi M.H., Paquez F., et al. Interviews with anti-HIV-positive individuals detected through the systematic screening of blood donations: Consequences for predonation medical interview. Vox Sang 62 (1992) 25-28
24. Van der Bij A.K., Coutinho R.A., and Van der Poel C.L. Surveillance of risk profiles among new and repeat blood donors with transfusion-transmitted infections from 1995 through 2003 in the Netherlands. Transfusion 46 (2006) 1729-1736
25. American Medical Association. Report 5 of the Council on Science and Public Health (A-08): Revision of the lifetime deferral for blood donation of the men who have sex with men (MSM) population. June 20, 2008. Available at:. http://www.ama-assn.org/ama/pub/category/print/18644.html Last accessed Jun 26 2008
26. Rogers M.F., Simmonds R.J., Lawton K.E., et al. Guidelines for preventing transmission of human immunodeficiency virus through transplantation of human tissue and organs. MMWR Morb Mortal Wkly Rep 43 (1994) 1-17
27. Stramer S.L., Glynn S.A., Kleinman S.H., et al. Detection of HIV-1 and HCV infections among antibody-negative blood donors by nucleic-acid amplification testing. N Engl J Med 351 (2004) 760-768
28. Soldan K., Barbara J.A.J., Ramsay M.E., et al. Estimation of the risk of HBV, HCV and HIV infectious donations entering the blood supply in England, 1993-2001. Vox Sang 84 (2002) 274-286
29. Williams A.E., Thomson R.A., Schreiber G.B., et al. Estimates of infectious disease risk factors in US blood donors. JAMA 277 (1997) 967-972
30. Wang B., Schreiber G.B., Glynn S.A., et al. Does prevalence of transfusion-transmitted viral infection reflect corresponding incidence in United States blood donors?. Transfusion 45 (2005) 1089-1096
31. Whitaker B.K., and Sullivan M. The 2005 Nationwide Blood Collection and Utilization Survey Report (2006), Department of Health and Human Services, Washington, DC
32. Seed C., Lee J., Buring M., et al. Do prospective blood donors understand HCV and HIV risk factors? The Australian experience. Transfusion 42 Suppl. (2002) 72S [abstract]
33. Musto J.A., Seed C.R., Law M., et al. Estimating the risk of blood donation associated with HIV risk behaviors. Transfus Med 18 (2008) 49-54
34. Marrewijk C.M., Velduijzen I.K., Conyn van Spaendonck M.A., et al. Prevalence of hepatitis B viral markers in the Dutch population: A population based surveillance study (Pienter Project). Report #243680001 (2000), National Institute of Public Health and the Environment, Bilthoven
35. Dayton A.I. Deferral of MSM: Policy analysis. Presented at the 67th Meeting of the US Food and Drug Administration Blood Products Advisory Committee. Department of Health and Human Services Food and Drug Administration Center for Biologics Evaluation and Research, Gaithersburg (MD) September 14 (2000). http://www.fda.gov/ohrms/dockets/ac/00/transcripts/3649t1a.pdf Last accessed August 28, 2008
36. Germain M., Remis R.S., and Delage G. The risks and benefits of accepting men who have had sex with men as blood donors. Transfusion 43 (2003) 25-33
37. Soldan K., and Sinka K. Evaluation of the de-selection of men who have had sex with men from blood donation in England. Vox Sang 84 (2003) 265-273
38. Weber A.E., Chan K., George C., et al. Risk factors associated with HIV infection among young gay and bisexual men in Canada. J Acquir Immune Defic Syndr 28 (2001) 81-88
39. Dodd R.Y., Notari IV E.P., and Stramer S.L. Current prevalence and incidence of infectious disease markers and estimated window-period risk in the American Red Cross blood donor population. Transfusion 42 (2002) 975-979
40. O'Brien S.F., Yi Q.L., Fan W., et al. Current incidence and estimated residual risk of transfusion-transmitted infections in donations made to Canadian Blood Services. Transfusion 47 (2007) 316-325
41. Martin J.N. Diagnosis and epidemiology of human herpesvirus 8 infection. Semin Hematol 40 (2003) 133-142
42. Martin J.N., Ganem D.E., Osmond D.H., et al. Sexual transmission and the natural history of human herpesvirus 8 infection. N Engl J Med 338 (1998) 948-954
43. Dukers N.H.T.M. Risk factors for HHV-8 seropositivity and HHV-8 seroconversion in a cohort of homosexual men. Am J Epidemiol 151 (2000) 213-214
44. Martin J.N., and Osmond D.H. Determining specific sexual practices associated with human herpesvirus 8 transmission. Am J Epidemiol 151 (2000) 225-229
45. Pellet P., Wright D.J., Engels E.A., et al. Multicenter comparison of serologic assays and estimation of HHV-8 seroprevalance in US blood donors. Transfusion 43 (2003) 1260-1268
46. Operskalski E.A., Busch M.P., Mosley J.W., et al. Blood donations and viruses. Lancet 349 (1997) 1327
47. Engels E.A., Eastman H., Ablashi D.V., et al. Risk of transfusion-associated transmission of human herpesvirus 8. J Natl Cancer Inst 91 (1999) 1773-1775
48. Dollard S., Nelson K., Ness P., et al. Possible (probable?) transmission of human herpesvirus 8 by blood transfusion in a historical US cohort. Transfusion 45 (2005) 500-503
49. Hladik W., Dollard S.D., Mermin J., et al. Transmission of human herpes virus 8 by blood transfusions. N Engl J Med 355 (2006) 1331-1338
50. Kumar N., McLean K., Inoue N., et al. Human herpesvirus 8 genoprevalence in populations at disparate risks of Kaposi's sarcoma. J Med Virol 79 (2007) 52-59
51. Blajchman M.A., and Vamvakas E.C. The continuing risk of transfusion-transmitted infections. N Engl J Med 355 (2006) 1303-1305
52. Dodd R.Y. Human herpes virus 8: What (not) to do?. Transfusion 45 (2005) 463-465
53. Vamvakas E.C., and Tegtmeier G.E. Herpes viruses. In: Barbara J.A.J., Regan F.A.M., and Contreras M.C. (Eds). Transfusion Microbiology (2008), Cambridge University Press, Cambridge, UK 35-58
54. Regamey N., Tamm M., Wernli M., et al. Transmission of human herpesvirus 8 infection from renal-transplant donors to recipients. N Engl J Med 339 (1998) 1358-1363
55. Wilson K., Wilson M., Hebert P.C., et al. The application of the precautionary principle to the blood system: The Canadian blood system's vCJD donor deferral policy. Transfus Med Rev 17 (2003) 89-94
56. Llewellyn C.A., Hewitt P.R., Knight R.S., et al. Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion. Lancet 363 (2004) 417-421
57. Pincock S. Government confirms second case of vCJD transmitted by blood transfusion. BMJ 329 (2004) 251
58. Peden A.H., Head M.W., Ritchie D.L., et al. Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient. Lancet 364 (2004) 527-529
59. Pealer L.N., Marfin A.A., Petersen L.R., et al. Transmission of West Nile virus through blood transfusion in the United States in 2002. N Engl J Med 349 (2003) 1236-1245
60. Collinge J., Whitfield J., McIntosh E., et al. Kuru in the 21st century-An acquired prion disease with very long incubation periods. Lancet 367 (2006) 2068-2074
61. McDonald C.P., and Blajchman M.A. Bacterial contamination in blood and blood components. In: Barbara J.S.J., Regan F., and Contreras M.C. (Eds). Transfusion Microbiology (2008), Cambridge University Press, Cambridge, UK 87-115
62. Ness P., Braine N., King K., et al. Single-donor platelets reduce the risk of septic platelet transfusion reactions. Transfusion 41 (2001) 857-861
63. Murphy W.G., Foley M., Doherty C., et al. Screening platelet concentrates for bacterial contamination: Low numbers of bacteria and slow growth in contaminated units mandate an alternate approach to product safety. Vox Sang 95 (2008) 13-19
64. Benjamin R.J., and Wagner S.J. The residual risk of sepsis: Modeling the effect of concentration on bacterial detection in two-bottle culture systems and an estimation of false-negative culture rates. Transfusion 47 (2007) 1381-1389
65. Eder A.F., Kennedy J.M., Dy B.A., et al. Bacterial screening of apheresis platelets and the residual risk of septic transfusion reactions: The American Red Cross experience (2004-2006). Transfusion 47 (2007) 1134-1142
66. FDA/CBER. Fatalities reported to the FDA following blood collection and transfusion. Annual summary for fiscal years 2005 and 2006. Available at:. http://www.fda.gov/cber/blood/fatal0506.htm Accessed August 28, 2008
67. Brooks J.P. The rights of blood recipients should supersede any asserted rights of blood donors. Vox Sang 87 (2004) 280-286
68. Franklin I.M. Is there a right to donate blood? Patient rights; donor responsibilities. Transfus Med 17 (2007) 161-168
69. Hrudey S., and Leiss W. Risk management and precaution: Insights on the cautious use of evidence. Environ Health Perspect 111 (2003) 1577-1581