Evaluation of plasma enzyme activities using gas chromatography-mass spectrometry based steroid signatures

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 32, 2009, Pages 4125-4132

  Ha, Young Wan ^a   Moon, Ju Yeon ^a,b   Jung, Hyun Jin ^a,b   Chung, Bong Chul ^a   Choi, Man Ho ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Yonsei University   (South Korea)

Author keywords

Enzyme activity; GC MS; Metabolite profiling; Plasma; Steroid

Indexed keywords

ANDROSTANE; BIOLOGICAL ACTIONS; CORRELATION COEFFICIENT; DATA TRANSFORMATION; DIHYDROTESTOSTERONE; DRUG ADMINISTRATION; DRUG EVALUATION; EXTRACTION EFFICIENCIES; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GC-MS; HIERARCHICAL CLUSTERING ANALYSIS; L-ASCORBIC ACID; LIMIT OF QUANTIFICATIONS; METABOLIC CHANGES; METABOLITE PROFILING; PEAK SHAPES; PLASMA SAMPLES; QUANTITATIVE VISUALIZATION; TRIMETHYLSILYL DERIVATIVES; Z-SCORES;

BIOMOLECULES; CHROMATOGRAPHIC ANALYSIS; CONTROLLED DRUG DELIVERY; ENZYMES; EXTRACTION; GAS CHROMATOGRAPHY; KETONES; LIPIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLISM; METABOLITES; ORGANIC ACIDS; PHENOLS; PLASMAS; VISUALIZATION;

ENZYME ACTIVITY;

5BETA ANDROSTANE DERIVATIVE; ALLOTETRAHYDROCORTISOL; ANDROGEN; ANDROSTANEDIONE; ANDROSTANOLONE; ASCORBIC ACID; CATECHOL ESTROGEN; CORTICOSTEROID; DUTASTERIDE; ESTROGEN; GESTAGEN; STEROID; STEROID 5ALPHA REDUCTASE; STEROID 5ALPHA REDUCTASE 1; STEROID 5ALPHA REDUCTASE 2; TESTOSTERONE; TETRAHYDROCORTISOL; TRIMETHYLSILYL DERIVATIVE; UNCLASSIFIED DRUG;

ACCURACY; ANDROGEN BLOOD LEVEL; ARTICLE; CLUSTER ANALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; HORMONE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; MALE; MASS FRAGMENTOGRAPHY; NORMAL HUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STEROID BLOOD LEVEL; VALIDATION STUDY;

ADULT; AZASTEROIDS; ENZYME ACTIVATION; ENZYME INHIBITORS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; MALE; PLASMA; SENSITIVITY AND SPECIFICITY; STEROIDS;

EID: 70649100104     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.11.010     Document Type: Article

References (39)

1. Hanukoglu I. J. Steroid Biochem. Mol. Biol. 43 (1992) 779
2. Payne A.H., and Hales D.B. Endocr. Rev. 25 (2004) 947
3. Falkenstein E., Tillmann H.C., Christ M., Feuring M., and Wehling M. Pharmacol. Rev. 52 (2000) 513
4. Bulun S.E., Yang S., Fang Z., Gurates B., Tamura M., Zhou J., and Sebastian S. J. Steroid Biochem. Mol. Biol. 79 (2001) 19
5. Caulfield M.P., Lynn T., Gottschalk M.E., Jones K.L., Taylor N.F., Malunowicz E.M., Shackleton C.H., Reitz R.E., and Fisher D.A. J. Clin. Endocrinol. Metab. 87 (2002) 3682
6. Choi M.H., Hahm J.R., Jung B.H., and Chung B.C. Clin. Chim. Acta 320 (2002) 95
7. Scott R.R., and Miller W.L. Horm. Res. 69 (2008) 266
8. Simard J., Ricketts M.L., Gingras S., Soucy P., Feltus F.A., and Melner M.H. Endocr. Rev. 26 (2005) 525
9. White P.C., and Speiser P.W. Endocr. Rev. 21 (2000) 245
10. Wong S.L., Shu S.G., and Tsai C.R. J. Formos. Med. Assoc. 105 (2006) 177
11. Bartsch G., Rittmaster R.S., and Klocker H. Eur. Urol. 37 (2000) 367
12. Choi M.H., Yoo Y.S., and Chung B.C. J. Invest. Dermatol. 116 (2001) 57
13. Thomas L.N., Douglas R.C., Lazier C.B., Too C.K., Rittmaster R.S., and Tindall D.J. Eur. Urol. 53 (2008) 244
14. Leyden J., Dunlap F., Miller B., Winters P., Lebwohl M., Hecker D., Kraus S., Baldwin H., Shalita A., Draelos Z., Markou M., Thiboutot D., Rapaport M., Kang S., Kelly T., Pariser D., Webster G., Hordinsky M., Rietschel R., Katz H.I., Terranella L., Best S., Round E., and Waldstreicher J. J. Am. Acad. Dermatol. 40 (1999) 930
15. Roehrborn C.G., Marks L.S., Fenter T., Freedman S., Tuttle J., Gittleman M., Morrill B., and Wolford E.T. Urology 63 (2004) 709
16. Hsing A.W., Stanczyk F.Z., Belanger A., Schroeder P., Chang L., Falk R.T., and Fears T.R. Cancer Epidemiol. Biomarkers Prev. 16 (2007) 1004
17. Wong T., Shackleton C.H., Covey T.R., and Ellis G. Clin. Chem. 38 (1992) 1830
18. Wood L., Ducroq D.H., Fraser H.L., Gillingwater S., Evans C., Pickett A.J., Rees D.W., John R., and Turkes A. Ann. Clin. Biochem. 45 (2008) 380
19. Cho H.J., Kim J.D., Lee W.Y., Chung B.C., and Choi M.H. Anal. Chim. Acta 632 (2009) 101
20. Meffre D., Pianos A., Liere P., Eychenne B., Cambourg A., Schumacher M., Stein D.G., and Guennoun R. Endocrinology 148 (2007) 2505
21. Moon J.Y., Jung H.J., Moon M.H., Chung B.C., and Choi M.H. Steroids 73 (2008) 1090
22. Palermo M., Gomez-Sanchez C., Roitman E., and Shackleton C.H. Steroids 61 (1996) 583
23. Semmes O.J. Cancer Epidemiol. Biomarkers Prev. 13 (2004) 1555
24. Ivshina A.V., George J., Senko O., Mow B., Putti T.C., Smeds J., Lindahl T., Pawitan Y., Hall P., Nordgren H., Wong J.E., Liu E.T., Bergh J., Kuznetsov V.A., and Miller L.D. Cancer Res. 66 (2006) 10292
25. Ray S., Britschgi M., Herbert C., Takeda-Uchimura Y., Boxer A., Blennow K., Friedman L.F., Galasko D.R., Jutel M., Karydas A., Kaye J.A., Leszek J., Miller B.L., Minthon L., Quinn J.F., Rabinovici G.D., Robinson W.H., Sabbagh M.N., So Y.T., Sparks D.L., Tabaton M., Tinklenberg J., Yesavage J.A., Tibshirani R., and Wyss-Coray T. Nat. Med. 13 (2007) 1359
26. Rhodes D.R., and Chinnaiyan A.M. Nat. Genet. 37 Suppl. (2005) S31
27. Denkert C., Budczies J., Kind T., Weichert W., Tablack P., Sehouli J., Niesporek S., Konsgen D., Dietel M., and Fiehn O. Cancer Res. 66 (2006) 10795
28. Kaddurah-Daouk R., Kristal B.S., and Weinshilboum R.M. Annu. Rev. Pharmacol. Toxicol. 48 (2008) 653
29. Choi M.H., Kim K.R., Hong J.K., Park S.J., and Chung B.C. Rapid Commun. Mass. Spectrom. 16 (2002) 2221
30. Choi M.H., Kim K.R., Kim D.H., and Chung B.C. Chromatographia 54 (2001) 765
31. Lee S.H., Woo H.M., Jung B.H., Lee J., Kwon O.S., Pyo H.S., Choi M.H., and Chung B.C. Anal. Chem. 79 (2007) 6102
32. Zacharia L.C., Dubey R.K., and Jackson E.K. Steroids 69 (2004) 255
33. Xu X., Veenstra T.D., Fox S.D., Roman J.M., Issaq H.J., Falk R., Saavedra J.E., Keefer L.K., and Ziegler R.G. Anal. Chem. 77 (2005) 6646
34. Gelbke H.P., and Knuppen R. J. Chromatogr. 71 (1972) 465
35. Lonning P.E., Skulstad P., Sunde A., and Thorsen T. J. Steroid Biochem. 32 (1989) 91
36. Bramson H.N., Hermann D., Batchelor K.W., Lee F.W., James M.K., and Frye S.V. J. Pharmacol. Exp. Ther. 282 (1997) 1496
37. Clark R.V., Hermann D.J., Cunningham G.R., Wilson T.H., Morrill B.B., and Hobbs S. J. Clin. Endocrinol. Metab. 89 (2004) 2179
38. Roehrborn C.G., Boyle P., Nickel J.C., Hoefner K., and Andriole G. Urology 60 (2002) 434
39. Rogers N.E., and Avram M.R. J. Am. Acad. Dermatol. 59 (2008) 547