Influence of neurotoxoplasmosis characteristics on real-time PCR sensitivity among AIDS patients in Brazil

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 104, Issue 1, 2010, Pages 24-28

  Correia, Carolina C ^a,b   Melo, Heloísa R L ^a   Costa, Vláudia M A ^a  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^b FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

Author keywords

AIDS; Brazil; Cerebral toxoplasmosis; Diagnosis; Polymerase chain reaction; Sensitivity and specificity

Indexed keywords

PROTEIN B1; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; BLOOD ANALYSIS; BRAZIL; CEREBROSPINAL FLUID ANALYSIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENCEPHALITIS; FEMALE; GENE IDENTIFICATION; GENE LOCATION; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; PLEOCYTOSIS; PREDICTION; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; TOXOPLASMA GONDII; TOXOPLASMOSIS; VALIDATION STUDY;

ADULT; AIDS-RELATED OPPORTUNISTIC INFECTIONS; BRAZIL; DNA, PROTOZOAN; FEMALE; HIV-1; HUMANS; MALE; PREDICTIVE VALUE OF TESTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; TOXOPLASMA; TOXOPLASMOSIS, CEREBRAL;

NUCLEOPOLYHEDROVIRUS; TOXOPLASMA GONDII;

EID: 70649098246     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trstmh.2009.06.012     Document Type: Article

References (33)

1. Hill D., and Dubey J.P. Toxoplasma gondii: transmission, diagnosis and prevention. Clin Microbiol Infect 8 (2002) 634-640
2. Antinori A., Larussa D., Cingolani A., Lorenzini P., Bossolasco S., Finazzi M.G., et al. Prevalence, associated factors, and prognostic determinants of AIDS-related toxoplasmic encephalitis in the era of advanced highly active antiretroviral therapy. Clin Infect Dis 39 (2004) 1681-1691
3. Camara V.D., Tavares W., Ribeiro M., and Dumas M. Neurological manifestations of toxoplasmosis in AIDS [in Portuguese]. J Bras Doenças Sex Transm 15 (2003) 46-50
4. Nissapatorn V., Lee C., Quek K.F., Leong C.L., Mahmud R., and Abdullah K.A. Toxoplasmosis in HIV/AIDS patients: a current situation. Jpn J Infect Dis 57 (2004) 160-165
5. Skiest D.J. Focal neurological disease in patients with acquired immunodeficiency syndrome. Clin Infect Dis 34 (2002) 103-115
6. Schoeder P.C., Post M.J.D., Oschatz E., Stadler A., Bruce-Gregorios J., and Thurnher M.M. Analysis of the utility of diffusion-weighted MRI and apparent diffusion coefficient values in distinguishing central nervous system toxoplasmosis from lymphoma. Neuroradiology 48 (2006) 715-720
7. Kompalic-Cristo A., Britto C., and Fernandes O. Molecular diagnosis of toxoplasmosis: review [in Portuguese]. J Bras Patol Med Lab 41 (2005) 222-235
8. Montoya J.G. Laboratory diagnosis of Toxoplasma gondii infection and toxoplasmosis. J Infect Dis 185 Suppl 1 (2002) S73-82
9. Gonçalves-Ferreira A.J., Herculano-Carvalho M., and Pimentel J. Stereotactic biopsies of focal brainstem lesions. Surg Neurol 60 (2003) 311-320
10. Hornef M.W., Iten A., Maeder P., Villemure J.G., and Regli L. Brain biopsy in patients with acquired immunodeficiency syndrome. Arch Intern Med 159 (1999) 2590-2596
11. Hoffmann C. Opportunistic infections. In: Hoffmann C., Rockstroh J.K., and Kamps B.S. (Eds). HIV medicine. 14th ed. (2006), Flying Publisher, Paris 406-411
12. Batra A., Tripathi P., and Gorthi S.P. Magnetic resonance evolution of cerebral toxoplasmosis in patients with acquired immunodeficiency. Acta Radiol 45 (2004) 212-221
13. Colombo F.A., Vidal J.E., Oliveira A.C.P., Hernandez A.V., Bonasser-Filho F., Nogueira R.S., et al. Diagnosis of cerebral toxoplasmosis in AIDS patients in Brazil: importance of molecular and immunological methods using peripheral blood samples. J Clin Microbiol 43 (2005) 5044-5047
14. Chang L., Cornford M.E., Chiang F.L., Ernst T.M., Sun N.C.J., and Miller B.L. Radiologic-pathologic correlation. Cerebral toxoplasmosis and lymphoma in AIDS. AJNR Am J Neuroradiol 15 (1995) 1653-1663
15. Dupon M., Cazenave J., Pellegrin J.L., Ragnaud J.M., Cheyrou A., Fischer I., et al. Detection of Toxoplasma gondii by PCR and tissue culture in cerebrospinal fluid and blood of human immunodeficiency virus-seropositive patients. J Clin Microbiol 33 (1995) 2421-2426
16. Remington J.S., Thulliez P., and Montoya J.G. Recent developments for diagnosis of toxoplasmosis. J Clin Microbiol 42 (2004) 941-945
17. Lin M.H., Chen T.C., Kuo T.T., Tseng C.C., and Tseng C.P. Real-time PCR for quantitative detection of Toxoplasma gondii. J Clin Microbiol 38 (2000) 4121-4125
18. Sackett D.L., and Haynes R.B. Evidence base of clinical diagnosis-the architecture of diagnostic research. BMJ 324 (2002) 539-541
19. Flahault A., Cadilhac M., and Thomas G. Sample size calculation should be performed for design accuracy in diagnostic test studies. J Clin Epidemiol 58 (2005) 859-862
20. Pelloux H., Guy E., Angelici M.C., Aspock H., Bessières M.H., Blatz R., et al. A second European collaborative study on polymerase chain reaction for Toxoplasma gondii, involving 15 teams. FEMS Microbiol Lett 165 (1998) 231
21. Vidal J.E., Colombo A., Oliveira A.C.P., Focaccia R., and Pereira-Chioccola V.L. PCR assay using cerebrospinal fluid for diagnosis of cerebral toxoplasmosis in Brazilian AIDS patients. J Clin Microbiol 42 (2004) 4765-4768
22. Goto M., Takahashi T., and Iwamoto A. Detection of Toxoplasma gondii by polymerase chain reaction in cerebrospinal fluid from human immunodeficiency virus-1-infected Japanese patients with focal neurological signs. J Int Med Res 32 (2004) 665-670
23. Joseph P., Calderón M.M., Gilman R.H., Quispe M.L., Cok J., Ticona E., et al. Optimization and evaluation of a PCR assay for detecting toxoplasmic encephalitis in patients with AIDS. J Clin Microbiol 40 (2002) 4499-4503
24. Reischl U., Bretagne S., Krüger D., Ernault P., and Costa J.M. Comparison of two DNA targets for the diagnosis of toxoplasmosis by real-time PCR using fluorescence resonance energy transfer hybridization probes. BMC Infect Dis 3 (2003) 7
25. Cockerill III F.R. Application of rapid-cycle real-time polymerase chain reaction for diagnostic testing in the clinical microbiology laboratory. Arch Pathol Lab Med 127 (2003) 1112-1120
26. Alfonso Y., Fraga J., Cox R., Bandera F., Pomier O., Fonseca C., et al. Comparison of four DNA extraction methods from cerebrospinal fluid for the detection of Toxoplasma gondii by polymerase chain reaction in AIDS patients. Med Sci Monit 14 (2008) MT1-6
27. Bretagne S. Molecular diagnostics in clinical parasitology and mycology: limits of the current polymerase chain reaction (PCR) assays and interest of the real-time PCR assays. Clin Microbiol Infect 9 (2003) 505-511
28. Bastien P., Procop G.W., and Reischl U. Quantitative real-time PCR is not more sensitive than "conventional" PCR. J Clin Microbiol 46 (2008) 1897-1900
29. Cassaing S., Bessières M.H., Berry A., Berrebi A., Fabre R., and Magnaval J.F. Comparison between two amplification sets for molecular diagnosis of toxoplasmosis by real-time PCR. J Clin Microbiol 44 (2006) 720-724
30. Kupferschimidt O., Kruger D., Held T.K., Ellerbrok H., Siegert W., and Janitschke K. Quantitative detection of Toxoplasma gondii DNA in human body fluids by TaqMan polymerase chain reaction. Clin Microbiol Infect 7 (2001) 120-124
31. Benson C.A., Kaplan J.E., Masur H., Pau A., and Homes K.K. Treating opportunistic infections among HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association/Infectious Diseases Society of America. Clin Infect Dis 40 Suppl 3 (2005) S131-235
32. Franzen C., Altfeld M., Hegener P., Hartmann P., Arendt G., Jablonowski H., et al. Limited value of PCR for detection of Toxoplasma gondii in blood from human immunodeficiency virus-infected patients. J Clin Microbiol 35 (1997) 2639-2641
33. Raffi F., Aboulker J.P., Michelet C., Reliquet V., Pelloux H., Huart A., et al. A prospective study of criteria for the diagnosis of toxoplasmic encephalitis in 186 AIDS patients. The BIOTOXO Study Group. AIDS 11 (1997) 177-184