Identification of potent biodegradable adjuvants that efficiently break self-tolerance-A key issue in the development of therapeutic vaccines

Vaccine

Volumn 28, Issue 1, 2009, Pages 48-52

  Ringvall, Maria ^a   Huijbers, Elisabeth J M ^a   Ahooghalandari, Parvin ^a   Alekseeva, Ludmila ^b   Andronova, Tatyana ^b   Olsson, Anna Karin ^a   Hellman, Lars ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

Adjuvant; Anti self response; CpG; Stimulatory DNA; Therapeutic vaccines

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CPG OLIGONUCLEOTIDE 1826; CPG OLIGONUCLEOTIDE B; DNA; DOUBLE STRANDED RNA; FREUND ADJUVANT; IMMUNOGLOBULIN E; IMMUNOLOGICAL ADJUVANT; MN 720; MONTANIDE ISA720; MURAMYL DIPEPTIDE DERIVATIVE; N ACETYLGLUCOSEAMINE 1 4 N ACETYLMURAMYL ALANYL DEXTRO DISOGLUTAMINE; N ACETYLGLUCOSEAMINE 1 4 N ACETYLMURAMYL ALANYL DEXTRO GLUTAMIC ACID; ORO FUSION PROTEIN; PHOSPHOROTHIOIC ACID; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGENICITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; IMMUNOLOGICAL TOLERANCE; NONHUMAN; PRIORITY JOURNAL; RAT; T LYMPHOCYTE; VACCINATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODY FORMATION; AUTOANTIBODIES; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FREUND'S ADJUVANT; IMMUNOGLOBULIN E; IMMUNOGLOBULIN HEAVY CHAINS; MANNITOL; OLEIC ACIDS; RATS; RATS, WISTAR; RNA, DOUBLE-STRANDED; SELF TOLERANCE; VACCINES;

EID: 70649094267     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.09.122     Document Type: Article

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