Apamin reduces neuromuscular transmission by activating inhibitory muscarinic M2 receptors on motor nerve terminals

European Journal of Pharmacology

Volumn 626, Issue 2-3, 2010, Pages 239-243

  Silva, Ledyanne Francielle Casitas de Matos ^a   Ramos, Edivan Rodrigo de Paula ^a   Ambiel, Celia Regina ^a   Correia de Sá, Paulo ^b   Alves Do Prado, Wilson ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Apamin; Choline; Fade; Muscarinic receptors; Skeletal muscle

Indexed keywords

4 AMINOPYRIDINE; ACETYLCHOLINE; APAMIN; HEMICHOLINIUM 3; HEXAMETHONIUM; METHOCTRAMINE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; NICOTINIC RECEPTOR; PIRENZEPINE; TUBOCURARINE CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENTIATION; DRUG SCREENING; MALE; MUSCLE TETANIC CONTRACTION; NERVE ENDING; NERVE POTENTIAL; NERVE STIMULATION; NEUROMUSCULAR FUNCTION; NEUROMUSCULAR TRANSMISSION; NONHUMAN; PHRENIC NERVE; PRIORITY JOURNAL; RAT; TETANY;

ANIMALS; APAMIN; ELECTRIC STIMULATION; MALE; MOTOR NEURONS; PHRENIC NERVE; RATS; RATS, WISTAR; RECEPTOR, MUSCARINIC M2; REFRACTORY PERIOD, ELECTROPHYSIOLOGICAL; SYNAPTIC TRANSMISSION;

EID: 70649090108     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.09.064     Document Type: Article

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