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Volumn 4, Issue 3, 1998, Pages 165-178

pH-metric solubility. 1. Solubility-pH profiles from Bjerrum plots. Gibbs buffer and pK(a) in the solid state

Author keywords

[No Author keywords available]

Indexed keywords

BENZYDAMINE; BUPRENORPHINE; DIMETHYL SULFOXIDE; FLURBIPROFEN; WATER;

EID: 0031911963     PISSN: 14608081     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (95)

References (31)
  • 1
    • 0021876419 scopus 로고
    • Predictive relationships in the water solubility of salts of a nonsteroidal antiinflammatory drug
    • Anderson, B. D., Conradi, R. A. (1985) Predictive relationships in the water solubility of salts of a nonsteroidal antiinflammatory drug. J. Pharm. Sci. 74: 815-820
    • (1985) J. Pharm. Sci. , vol.74 , pp. 815-820
    • Anderson, B.D.1    Conradi, R.A.2
  • 2
    • 0001056344 scopus 로고    scopus 로고
    • Preparation of water-soluble compounds through salt formation
    • Wermuth, C. G. (ed) Academic Press, London
    • Anderson, B. D., Flora, K. P. (1996) Preparation of water-soluble compounds through salt formation. In: Wermuth, C. G. (ed) The Practice of Medicinal Chemistry. Academic Press, London, pp 739-754
    • (1996) The Practice of Medicinal Chemistry , pp. 739-754
    • Anderson, B.D.1    Flora, K.P.2
  • 3
    • 0002982195 scopus 로고
    • STBLTY: Methods for construction and refinement of equilibrium models
    • Leggett, D. J. (ed.) Plenum, New York
    • Avdeef, A. (1985) STBLTY: methods for construction and refinement of equilibrium models. In: Leggett, D. J. (ed.) Computational Methods for the Determination of Formation Constants. Plenum, New York, pp 355-473
    • (1985) Computational Methods for the Determination of Formation Constants , pp. 355-473
    • Avdeef, A.1
  • 4
    • 0027071736 scopus 로고
    • pH-metric log P. 1. Difference plots for determining ion-pair octanol-water partition coefficients of multiprotic substances
    • Avdeef, A. (1992) pH-metric log P. 1. Difference plots for determining ion-pair octanol-water partition coefficients of multiprotic substances. Quant. Struct. Act. Relat. 11: 510-517
    • (1992) Quant. Struct. Act. Relat. , vol.11 , pp. 510-517
    • Avdeef, A.1
  • 5
    • 0002854293 scopus 로고    scopus 로고
    • Assessment of distribution- PH profiles
    • Pliska, V., Testa, B., van de Waterbeemd, H. (eds) VCH, Weinheim
    • Avdeef, A. (1996) Assessment of distribution- pH profiles. In Pliska, V., Testa, B., van de Waterbeemd, H. (eds) Methods and Principles in Medicinal Chemistry. Vol. 5, VCH, Weinheim, pp 109-140
    • (1996) Methods and Principles in Medicinal Chemistry , vol.5 , pp. 109-140
    • Avdeef, A.1
  • 6
    • 0000434173 scopus 로고
    • Accurate measurements of the concentration of hydrogen ions with a glass electrode: Calibrations using the Prideaux and other universal buffer solutions and a computer-controlled automatic titrator
    • Avdeef, A., Bucher, J. J. (1978) Accurate measurements of the concentration of hydrogen ions with a glass electrode: calibrations using the Prideaux and other universal buffer solutions and a computer-controlled automatic titrator. Anal. Chem. 50: 2137-2142
    • (1978) Anal. Chem. , vol.50 , pp. 2137-2142
    • Avdeef, A.1    Bucher, J.J.2
  • 7
    • 0020202717 scopus 로고
    • Bjerrum plots for the determination of systematic concentration errors in titration data
    • Avdeef, A., Kearney, D. L., Brown, J. A., Chemotti, A. R., (1982) Bjerrum plots for the determination of systematic concentration errors in titration data. Anal. Chem. 54: 2322-2326
    • (1982) Anal. Chem. , vol.54 , pp. 2322-2326
    • Avdeef, A.1    Kearney, D.L.2    Brown, J.A.3    Chemotti, A.R.4
  • 9
    • 0029911418 scopus 로고    scopus 로고
    • pH-metric log P. 7. Octanol-, chloroform-, and PGDP-water partitioning of morphine-6-glucuronide and other related opiates
    • Avdeef, A., Barrett, D. A., Shaw, P. N., Knaggs, R. D., Davis, S. S. (1996) pH-metric log P. 7. Octanol-, chloroform-, and PGDP-water partitioning of morphine-6-glucuronide and other related opiates. J. Med. Chem. 39: 4377-4381
    • (1996) J. Med. Chem. , vol.39 , pp. 4377-4381
    • Avdeef, A.1    Barrett, D.A.2    Shaw, P.N.3    Knaggs, R.D.4    Davis, S.S.5
  • 10
    • 0031942688 scopus 로고    scopus 로고
    • pH-metric log P. 10. Determination of vescicle membrane-water partition coefficients of ionizable drugs
    • In press
    • Avdeef, A., Box, K. J., Comer, J. E. A., Hibbert, C., Tam, K. Y. (1998). pH-metric log P. 10. Determination of vescicle membrane-water partition coefficients of ionizable drugs. Pharm. Res. 15: In press
    • (1998) Pharm. Res. , vol.15
    • Avdeef, A.1    Box, K.J.2    Comer, J.E.A.3    Hibbert, C.4    Tam, K.Y.5
  • 12
    • 0018412446 scopus 로고
    • Solubility of doxycycline in aqueous solution
    • Bogardus, J. B., Blackwood, R. K. (1979) Solubility of doxycycline in aqueous solution. J. Pharm. Sci. 68: 188-194
    • (1979) J. Pharm. Sci. , vol.68 , pp. 188-194
    • Bogardus, J.B.1    Blackwood, R.K.2
  • 13
    • 0030944059 scopus 로고    scopus 로고
    • Spectral methods for the characterization of polymorphs and solvates
    • Brittain, H. G. (1997) Spectral methods for the characterization of polymorphs and solvates. J. Pharm. Sci. 86: 405-411.
    • (1997) J. Pharm. Sci. , vol.86 , pp. 405-411
    • Brittain, H.G.1
  • 14
    • 0018145767 scopus 로고
    • pH-Solubility profiles of organic carboxylic acids and their salts
    • Chowhan, Z. T. (1978) pH-Solubility profiles of organic carboxylic acids and their salts. J. Pharm. Sci. 67: 1257-1260
    • (1978) J. Pharm. Sci. , vol.67 , pp. 1257-1260
    • Chowhan, Z.T.1
  • 15
    • 0001440104 scopus 로고
    • Studies on the extraction of metal complexes. IV. the dissociation constants and partition coefficients of 8-quinolinol (oxine) and N-nitroso-N-phenylhydroxylamine (cupferron)
    • Dyrssen, D. (1952) Studies on the extraction of metal complexes. IV. The dissociation constants and partition coefficients of 8-quinolinol (oxine) and N-nitroso-N-phenylhydroxylamine (cupferron). Sv. Kem. Tidskr. 64: 213-224
    • (1952) Sv. Kem. Tidskr. , vol.64 , pp. 213-224
    • Dyrssen, D.1
  • 17
    • 0025153729 scopus 로고
    • Aqueous solubility properties of a dibasic peptide-like compound
    • Garren, K. W., Pyter, R. A. (1990) Aqueous solubility properties of a dibasic peptide-like compound. Ant. J. Pharmaceut. 63: 167-172
    • (1990) Ant. J. Pharmaceut. , vol.63 , pp. 167-172
    • Garren, K.W.1    Pyter, R.A.2
  • 18
    • 0030638567 scopus 로고    scopus 로고
    • Characterization and significance of the amorphous state in pharmaceutical systems
    • Hancock, B. C., Zografi, G. (1997) Characterization and significance of the amorphous state in pharmaceutical systems. J. Pharm. Sci. 86: 1-12
    • (1997) J. Pharm. Sci. , vol.86 , pp. 1-12
    • Hancock, B.C.1    Zografi, G.2
  • 19
    • 37049166942 scopus 로고
    • The calculation of formation curves of metal complexes from pH titration curves in mixed solvents
    • Irving, H. M., Rossotti, H. S. (1954) The calculation of formation curves of metal complexes from pH titration curves in mixed solvents. J. Chem. Soc. 2904-2910
    • (1954) J. Chem. Soc. , pp. 2904-2910
    • Irving, H.M.1    Rossotti, H.S.2
  • 20
    • 0016741904 scopus 로고
    • a's and partition and drug distribution coefficients of narcotics and narcotic antagonists and their pH and temperature dependence
    • a's and partition and drug distribution coefficients of narcotics and narcotic antagonists and their pH and temperature dependence. J. Med. Chem. 18: 647-655
    • (1975) J. Med. Chem. , vol.18 , pp. 647-655
    • Kaufman, J.J.1    Semo, N.M.2    Koski, W.S.3
  • 21
    • 0031024171 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski, C. A., Lombardo, F., Dominy, B. W., Feeney, P. J. (1997) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Delivery Rev. 23: 3-25
    • (1997) Adv. Drug Delivery Rev. , vol.23 , pp. 3-25
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 22
    • 0017112754 scopus 로고
    • Direct measurement of octanol-water partition coefficients by high-pressure liquid chromatography
    • Mirrlees, M. S., Moulton, S. J., Murphy, C. T., Taylor, P. J. (1976) Direct measurement of octanol-water partition coefficients by high-pressure liquid chromatography. J. Med. Chem. 19: 615-619
    • (1976) J. Med. Chem. , vol.19 , pp. 615-619
    • Mirrlees, M.S.1    Moulton, S.J.2    Murphy, C.T.3    Taylor, P.J.4
  • 23
    • 0029331707 scopus 로고
    • Thermodynamics of solute partitioning into immobilized artificial membranes
    • Ong, S., Pidgeon, C. (1995) Thermodynamics of solute partitioning into immobilized artificial membranes. Anal. Chem. 67: 2119-2128
    • (1995) Anal. Chem. , vol.67 , pp. 2119-2128
    • Ong, S.1    Pidgeon, C.2
  • 24
    • 0015868160 scopus 로고
    • Physicochemical properties of prostaglandin F2, (tromethamine salt): Solubility behaviour, surface properties, and ionization constants
    • Roseman, T. J., Yalkowsky, S. H. (1973) Physicochemical properties of prostaglandin F2, (tromethamine salt): solubility behaviour, surface properties, and ionization constants. J. Pharm. Sci. 62: 1680-1685
    • (1973) J. Pharm. Sci. , vol.62 , pp. 1680-1685
    • Roseman, T.J.1    Yalkowsky, S.H.2
  • 25
    • 0000785514 scopus 로고
    • Peptide syntheses through rational approaches
    • Magee, P. S., Kohn, G. K., Menn, J. J. (eds) Amer. Chem. Soc., Washington
    • Scherrer, R. A. (1984) Peptide syntheses through rational approaches. In: Magee, P. S., Kohn, G. K., Menn, J. J. (eds) Amer. Chem. Soc. Symposium Ser. 255. Amer. Chem. Soc., Washington, pp 225-246
    • (1984) Amer. Chem. Soc. Symposium Ser. , vol.255 , pp. 225-246
    • Scherrer, R.A.1
  • 26
    • 0016163904 scopus 로고
    • The simultaneous determination of partition coefficients and acidity constant of a substance
    • Seiler, P. (1974) The simultaneous determination of partition coefficients and acidity constant of a substance. Eur. J. Med. Chem. Chim. Therapeut. 9: 665-666
    • (1974) Eur. J. Med. Chem. Chim. Therapeut. , vol.9 , pp. 665-666
    • Seiler, P.1
  • 29
    • 0021702316 scopus 로고
    • General treatment of pH-solubility profiles of weak acids and bases and the effect of different acids on the solubility of a weak base
    • Streng, W. H., Hsi, S. K., Helms, P. E., Tan, H. G. H. (1984) General treatment of pH-solubility profiles of weak acids and bases and the effect of different acids on the solubility of a weak base. J. Pharm. Sci. 73: 1679-1684
    • (1984) J. Pharm. Sci. , vol.73 , pp. 1679-1684
    • Streng, W.H.1    Hsi, S.K.2    Helms, P.E.3    Tan, H.G.H.4
  • 30


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.